Unsteady aerodynamic effects in small-amplitude pitch oscillations of an airfoil

High-fidelity wall-resolved large-eddy simulations (LES) are utilized to investigate the flow-physics of small-amplitude pitch oscillations of an airfoil at Re = 100,000. The investigation of the unsteady phenomenon is done in the context of natural laminar flow airfoils, which can display sensitive dependence of the aerodynamic forces on the angle of attack in certain "off-design" conditions. The dynamic range of the pitch oscillations is chosen to be in this sensitive region. Large variations of the transition point on the suction-side of the airfoil are observed throughout the pitch cycle resulting in a dynamically rich flow response. Changes in the stability characteristics of a leading-edge laminar separation bubble has a dominating influence on the boundary layer dynamics and causes an abrupt change in the transition location over the airfoil. The LES procedure is based on a relaxation-term which models the dissipation of the smallest unresolved scales. The validation of the procedure is provided for channel flows and for a stationary wing at Re = 400,000.Comment: 37 pages. 19 figure

On the role of actuation for the control of streaky structures in boundary layers

This work deals with the closed-loop control of streaky structures induced by free-stream turbulence in a zero-pressure gradient, transitional boundary layer, by means of localized sensors and actuators. A linear quadratic gaussian regulator is considered along with a system identification technique to build reduced-order models for control. Three actuators are developed with different spatial supports, corresponding to a baseline shape with only vertical forcing, and to two other shapes obtained by different optimization procedures. A computationally efficient method is derived to obtain an actuator which aims to induce the exact structures which are inside the boundary layer, given in terms of their first spectral proper orthogonal decomposition mode, and an actuator that maximizes the energy of induced downstream structures. Two free-stream turbulence levels were evaluated, corresponding to 3.0% and 3.5%, and closed-loop control is applied in large-eddy simulations of transitional boundary layers. All three actuators lead to significant delays in the transition to turbulence and were shown to be robust to mild variations in the free-stream turbulence levels. Differences are understood in terms of the SPOD of actuation and FST-induced fields along with the causality of the control scheme. The actuator optimized to generate the leading downstream SPOD mode, representing the streaks in the open-loop flow, leads to the highest transition delay, which can be understood due to its capability of closely cancelling structures in the boundary layer. However, it is shown that even with the actuator located downstream of the input measurement it may become impossible to cancel incoming disturbances in a causal way, depending on the wall-normal position of the output and on the actuator considered, which limits sensor and actuator placement capable of good closed-loop performance.Comment: 33 pages, 19 figure

Self-force on a scalar charge in radial infall from rest using the Hadamard-WKB expansion

We present an analytic method based on the Hadamard-WKB expansion to calculate the self-force for a particle with scalar charge that undergoes radial infall in a Schwarzschild spacetime after being held at rest until a time t = 0. Our result is valid in the case of short duration from the start. It is possible to use the Hadamard-WKB expansion in this case because the value of the integral of the retarded Green's function over the particle's entire past trajectory can be expressed in terms of two integrals over the time period that the particle has been falling. This analytic result is expected to be useful as a check for numerical prescriptions including those involving mode sum regularization and for any other analytical approximations to self-force calculations.Comment: 22 pages, 2 figures, Physical Review D version along with the corrections given in the erratu

Automated equivalence checking of concurrent quantum systems

The novel field of quantum computation and quantum information has gathered significant momentum in the last few years. It has the potential to radically impact the future of information technology and in influence the development of modern society. The construction of practical, general purpose quantum computers has been challenging, but quantum cryptographic and communication devices have been available in the commercial marketplace for several years. Quantum networks have been built in various cities around the world and a dedicated satellite has been launched by China to provide secure quantum communication. Such new technologies demand rigorous analysis and verification before they can be trusted in safety- and security- critical applications. Experience with classical hardware and software systems has shown the difficulty of achieving robust and reliable implementations. We present CCSq, a concurrent language for describing quantum systems, and develop verification techniques for checking equivalence between CCSq processes. CCSq has well-defined operational and superoperator semantics for protocols that are functional, in the sense of computing a deterministic input-output relation for all interleavings arising from concurrency in the system. We have implemented QEC (Quantum Equivalence Checker), a tool which takes the specification and implementation of quantum protocols, described in CCSq, and automatically checks their equivalence. For efficiency purposes, we restrict ourselves to Clifford operators in the stabilizer formalism, but we are able to verify protocols over all input states. We have specified and verified a collection of interesting and practical quantum protocols ranging from quantum communication and quantum cryptography to quantum error correction

Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates.

Zika virus (ZIKV) infection is associated with congenital defects and pregnancy loss. Here, we found that 26% of nonhuman primates infected with Asian/American ZIKV in early gestation experienced fetal demise later in pregnancy despite showing few clinical signs of infection. Pregnancy loss due to asymptomatic ZIKV infection may therefore be a common but under-recognized adverse outcome related to maternal ZIKV infection

Non-iterative vortex-based smearing correction for the actuator line method

The actuator line method (ALM) is extensively used in wind turbine and rotor simulations. However, its original uncorrected formulation overestimates the forces near the tip of the blades and does not reproduce well forces on translating wings. The recently proposed vortex-based smearing correction for the ALM is a correction based on physical and mathematical properties of the simulation that allows for a more accurate and general ALM. So far, to correct the forces on the blades, the smearing correction depended on an iterative process at every time step, which is usually slower, less stable and less deterministic than direct methods. In this work, a non-iterative process is proposed and validated. First, we propose a formulation of the non-linear lifting line that is equivalent to the ALM with smearing correction, showing that their results are practically identical for a translating wing. Then, by linearizing the lifting line method, the iterative process of the correction is substituted by the direct solution of a small linear system. No significant difference is observed in the results of the iterative and non-iterative corrections, both in wing and rotor simulations. Additional contributions of the present work include the use of a more accurate approximation for the velocity induced by a smeared vortex segment and the implementation of a free-vortex wake model to define the vortex sheet, that contribute to the accuracy and generality of the method. The results present here may motivate the adoption of the ALM by other communities, for example, in fixed-wing applications.Comment: 30 pages, 9 figure

Uniparental Genetic Heritage of Belarusians: Encounter of Rare Middle Eastern Matrilineages with a Central European Mitochondrial DNA Pool

Ethnic Belarusians make up more than 80% of the nine and half million people inhabiting the Republic of Belarus. Belarusians together with Ukrainians and Russians represent the East Slavic linguistic group, largest both in numbers and territory, inhabiting East Europe alongside Baltic-, Finno-Permic- and Turkic-speaking people. Till date, only a limited number of low resolution genetic studies have been performed on this population. Therefore, with the phylogeographic analysis of 565 Y-chromosomes and 267 mitochondrial DNAs from six well covered geographic sub-regions of Belarus we strove to complement the existing genetic profile of eastern Europeans. Our results reveal that around 80% of the paternal Belarusian gene pool is composed of R1a, I2a and N1c Y-chromosome haplogroups – a profile which is very similar to the two other eastern European populations – Ukrainians and Russians. The maternal Belarusian gene pool encompasses a full range of West Eurasian haplogroups and agrees well with the genetic structure of central-east European populations. Our data attest that latitudinal gradients characterize the variation of the uniparentally transmitted gene pools of modern Belarusians. In particular, the Y-chromosome reflects movements of people in central-east Europe, starting probably as early as the beginning of the Holocene. Furthermore, the matrilineal legacy of Belarusians retains two rare mitochondrial DNA haplogroups, N1a3 and N3, whose phylogeographies were explored in detail after de novo sequencing of 20 and 13 complete mitogenomes, respectively, from all over Eurasia. Our phylogeographic analyses reveal that two mitochondrial DNA lineages, N3 and N1a3, both of Middle Eastern origin, might mark distinct events of matrilineal gene flow to Europe: during the mid-Holocene period and around the Pleistocene-Holocene transition, respectively

Disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE) in Iran and its neighboring countries, 1990–2015

BACKGROUND: Summary measures of health are essential in making estimates of health status that are comparable across time and place. They can be used for assessing the performance of health systems, informing effective policy making, and monitoring the progress of nations toward achievement of sustainable development goals. The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) provides disability-adjusted life-years (DALYs) and healthy life expectancy (HALE) as main summary measures of health. We assessed the trends of health status in Iran and 15 neighboring countries using these summary measures. METHODS: We used the results of GBD 2015 to present the levels and trends of DALYs, life expectancy (LE), and HALE in Iran and its 15 neighboring countries from 1990 to 2015. For each country, we assessed the ratio of observed levels of DALYs and HALE to those expected based on socio-demographic index (SDI), an indicator composed of measures of total fertility rate, income per capita, and average years of schooling. RESULTS: All-age numbers of DALYs reached over 19 million years in Iran in 2015. The all-age number of DALYs has remained stable during the past two decades in Iran, despite the decreasing trends in all-age and age-standardized rates. The all-cause DALY rates decreased from 47,200 in 1990 to 28,400 per 100,000 in 2015. The share of non-communicable diseases in DALYs increased in Iran (from 42% to 74%) and all of its neighbors between 1990 and 2015; the pattern of change is similar in almost all 16 countries. The DALY rates for NCDs and injuries in Iran were higher than global rates and the average rate in High Middle SDI countries, while those for communicable, maternal, neonatal, and nutritional disorders were much lower in Iran. Among men, cardiovascular diseases ranked first in all countries of the region except for Bahrain. Among women, they ranked first in 13 countries. Life expectancy and HALE show a consistent increase in all countries. Still, there are dissimilarities indicating a generally low LE and HALE in Afghanistan and Pakistan and high expectancy in Qatar, Kuwait, and Saudi Arabia. Iran ranked 11th in terms of LE at birth and 12th in terms of HALE at birth in 1990 which improved to 9th for both metrics in 2015. Turkey and Iran had the highest increase in LE and HALE from 1990 to 2015 while the lowest increase was observed in Armenia, Pakistan, Kuwait, Kazakhstan, Russia, and Iraq. CONCLUSIONS: The levels and trends in causes of DALYs, life expectancy, and HALE generally show similarities between the 16 countries, although differences exist. The differences observed between countries can be attributed to a myriad of determinants, including social, cultural, ethnic, religious, political, economic, and environmental factors as well as the performance of the health system. Investigating the differences between countries can inform more effective health policy and resource allocation. Concerted efforts at national and regional levels are required to tackle the emerging burden of non-communicable diseases and injuries in Iran and its neighbors

Direct numerical simulation of transition under free-stream turbulence and the influence of large integral length scales

Under action of free-stream turbulence (FST), elongated streamwise streaky structures are generated inside the boundary layer, and their amplitude and wavelength are crucial for the transition onset. While turbulence intensity is strongly correlated with the transitional Reynolds number, characteristic length scales of the FST are often considered to have a slight impact on the transition location. However, a recent experiment by Fransson & Shahinfar (2020} shows significant effects of FST scales. They found that, for higher free-stream turbulence levels and larger integral length scales, an increase in the length scale postpones transition, contrary to established literature. Here, we aim at understanding these results by performing a series of high-fidelity simulations. These results provide understanding why the FST integral length scale affects the transition location differently. These integral length scales are so large that the wide streaks introduced in the boundary layer have substantially lower growth in the laminar region upstream of the transition to turbulence, than streaks induced by smaller integral length scales. The energy in the boundary layer subsequently propagate to smaller spanwise scales as a result of the non-linear interaction. When the energy has reached smaller spanwise scales larger amplitude streaks results in regions where the streak growth are larger. It takes longer for the energy from the wider streaks to propagate to the spanwise scales associated with the breakdown to turbulence, than for the those with smaller spanwise scales. Thus there is a faster transition for FST with lower integral length scales in this case