The detection and classification of blast cell in Leukaemia Acute Promyelocytic Leukaemia (AML M3) blood using simulated annealing and neural networks

This paper was delivered at AIME 2011: 13th Conference on Artifical Intelligence in Medicine.This paper presents a method for the detection and classification of blast cells in M3 with others sub-types using simulated annealing and neural networks. In this paper, we increased our test result from 10 images to 20 images. We performed Hill Climbing, Simulated Annealing and Genetic Algorithms for detecting the blast cells. As a result, simulated annealing is the “best” heuristic search for detecting the leukaemia cells. From the detection, we performed features extraction on the blast cells and we classifying based on M3 and other sub-types using neural networks. We received convincing result which has targeting around 97% in classifying of M3 with other sub-types. Our results are based on real world image data from a Haematology Department.Universiti Sains Islam Malaysia and the Ministry of Higher Education, Malaysi

Anomalous Chiral Fermi Surface

We provide a geometrical argument for the emergence of a Wess-Zumino-Witten (WZW) term for a Fermi surface threaded by a Berry curvature. In the presence of external fields, the gauged WZW term yields a chiral (triangle) anomaly for the fermionic current at the edge of the Fermi surface. Fermion number is conserved though since the Berry curvatures occur always in pairs with opposite (monopole) charge. The anomalous vector and axial currents for a a fermionic fluid at low temperature threaded by pairs of Berry curvatures are discussed. The leading temperature correction to the chiral vortical effect in a slowly rotating Fermi surface threaded by a Berry curvature maybe tied to the gravitational anomaly.Comment: 4 pages; version to appear in PR

Frontiers of ovarian carcinosarcoma

Ovarian carcinosarcoma (OCS), also known as a malignant mixed Müllerian tumour (MMMT), is a rare and aggressive form of cancer that accounts for less than 5% of ovarian cancers. It is characterized by high morbidity and mortality rates, with a median overall survival (OS) of less than 2 years. Several factors, including advancing age, nulliparity, reduced lactation rates, decreased use of oral contraceptive pills, genetic mutations in BRCA (breast cancer) genes, and the use of assisted reproductive technology, may increase the risk of OCS. Poor prognostic factors include an advanced stage at diagnosis, older age, lymph node metastasis, suboptimal surgical cytoreduction, the presence of heterologous features on histopathology, and increased expression of vascular endothelial growth factor (VEGF), tumour protein p53, and p53 alongside Wilms tumour 1 (WT1). The main treatment approach for OCS is cytoreductive surgery followed by platinum-based chemotherapy, although immunotherapy is showing promise. Homologous recombination deficiency (HRD) testing may enhance outcomes by enabling personalized immunotherapy and targeted therapies for specific patient groups, thereby reducing unnecessary side effects and healthcare costs. However, there is currently a lack of standardised treatment regimens for OCS patients, with most studies consisting of case reports and a shortage of suitable comparator groups. This article aims to provide clinicians with information on the epidemiology, risk factors, prognostic factors, and latest therapeutic advancements in OCS

The Impact of Supervisory Inputs on Postgraduate Students

Pengawasan telah menjadi isu utama dalam studi di sekolah pascasarjana. Pengawasan dapat didefinisikan sebagai hubungan orang per orang secara intensif dan interpersonal. Pengawas dirancang untuk dapat memfasilitasi perkembangan akademik mahasiswa baik terkait dengan tugas maupun penelitian mereka. Paper ini menunjukkan betapa kompleksnya bidang pengawasan terhadap mahasiswa, yang dipengaruhi oleh banyak faktor, di antaranya latar belakang sosial, kepribadian pengawas dan mahasiswa, hubungan yang berkembang di antara mereka, keahlian pengawas, dan masalah-masalah yang dihadapi oleh para mahasiswa. Paper ini mendiskusikan pentingnya input-input kepengawasan dalam proses pengawasan, dan juga meneropong hakikat interaksi sosial antara pengawas dengan mahasiswa. Sasaran yang dituju dalam paper ini adalah untuk mengembangkan pengawasan yang efektif terhadap mahasiswa sekolah pascasarjana guna menghasilkan modal sumber daya manusia yang unggul. Kata kunci : pengawasan, mahasiswa pascasarjana, input kepengawasan, dan pengawasan efekti

Adaptive spatial mode of space-time and spacefrequency OFDM system over fading channels

In this paper we present a 2 transmit 1 receive (1 Tx : 1 Rx) adaptive spatial mode (ASM) of space-time (ST) and space-frequency (SF) orthogonal frequency division multiplexing (OFDM). At low signal to noise ratio (SNR) we employ ST-OFDM and switch to SF-OFDM at a certain SNR threshold. We determine this threshold from the intersection of individual performance curves. Results show a gain of 9 dB (at a bit error rate of 10-3) is achieved by employing adaptive spatial mode compared to a fixed ST-OFDM, almost 6 dB to fixed SF-OFDM, 4 dB to Coded ST-OFDM and 2 dB to a fixed coded SF-OFDM, at a delay spread of 700 ns