Biodiversity modelling in practice - predicting bird and woody plant species richness on farmlands

In light of decreasing species richness on farmland and an increasing awareness of biodiversity issues among customers and food companies, concepts and models to evaluate and enhance farmland biodiversity are greatly needed. It is important that the models are easy to apply as they have to be utilized by practitioners such as farmers and their consultants. In this study, simple but valid predictors were identified to rapidly assess the species richness of birds and woody plants in hedgerows, an important farmland landscape element. Hedgerows were sampled in seven agricultural landscapes throughout Germany. By means of automatic model selection procedures, linear regression models were estimated to predict bird and woody plant species richness. Cross validation procedures were carried out in order to visualize model selection uncertainty and estimate the prediction error. Due to a rather high prediction error, the model for plants can only be recommended for use when field work is not feasible. The model for birds, however, explained 70.8% of the variance in species numbers. It may help farmers, food companies and nature conservation agencies to rapidly evaluate bird species richness in hedgerows on farmland and to identify potentials and appropriate measures for enhancing it

Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors

SRY and other Sox-type transcription factors are important developmental regulators with various implications in human disease. In this study, we identified Exp4 (exportin 4) as an interaction partner of Sox2 in mouse embryonic stem cells and neural progenitors. We show that, besides its established function in nuclear export, Exp4 acts as a bona fide nuclear import receptor for Sox2 and SRY. Thus, Exp4 is an example of a nuclear transport receptor carrying distinct cargoes into different directions. In contrast to a published study, we observed that the import activity of Imp-α (importin-a) isoforms toward Sox2 is negligible. Instead, we found that Imp9 and the Imp-β/7 heterodimer mediate nuclear import of Sox2 in parallel to Exp4. Import signals for the three pathways overlap and include conserved residues in the Sox2 high-mobility group (HMG) box domain that are also critical for DNA binding. This suggests that nuclear import of Sox proteins is facilitated by several parallel import pathways