New silver complexes with ligands based on 4-substituted-3,6-dipyridin-2-ylpyridazines

Chapter I gives a brief introduction to supramolecular chemistry, silver chemistry, pyridazine chemistry. Chapter II discusses the general procedure used for this work. It introduces the Sonogashira reaction used to prepare the ethynyl precursors, and the inverse electron demand Diels Alder reaction used to synthesise all the ligands presented in this work. Chapter III describes the synthesis and the characterisation of phenyl substituted pyridazines and their silver complexes. This chapter presents the crystal structure of ligand 8. Chapter IV discusses the synthesis and characterisation of the halogenated pyridazine and their silver complexes. It also discusses the crystal structure of ligand 15 and complexes 15sc, 18sc and 20sc. Chapter V describes the synthesis of diverse pyridazines. These ligands have methoxy, cyano, tert-butyl phenyl substituents. It also shows the crystal structure of ligand 34 and complexes 30sc, 39sc, 42sc, 43sc and 49sc. Chapter VI discusses the synthesis and characterisation of pyridazine substituted with alkyl chains. The crystal structure of complex 53sc is presented. Chapter VII gives the conclusion to this work and a general overview of the ligands and complexes synthesised in this thesis

4-Substituted 3,6-bis(2-pyridyl) pyridazines: Silver(I) complexes of 4-cyano- and 4-(4-bromophenyl)-3,6-bis(2-pyridyl) pyridazine and pseudopolymorphs of 1,3,5-tris3,6-bis(2-pyridyl)pyridazin-4-ylbenzene

Metal: ligand complexes are crystallized from reaction mixtures of equimolar amounts of 4-cyano-3,6-bis(2-pyridyl)pyridazine 2 or 4-(4-bromophenyl)-3,6-bis(2-pyridyl)pyridazine 3 and silver(i) triflate. In [Ag2(2)(2)](2+), the two ligands adopt a head-to-tail arrangement, while a head-to-head motif is confirmed for the solid state structure of [Ag2(3)(2)](2+). In solution, one ligand environment is observed in each case. Silver(i) reacts with 1,3,5-tris3,6-bis(2pyridyl) pyridazin-4-yl benzene 4 to give highly insoluble powders. The single crystal structures of the pseudopolymorphs (4)center dot Et2O and 2(4)center dot 2MeCN center dot H2O are reported; in each structure, the ligand adopts the same conformation, derived from a C-s rather than C-3v model structure