4 research outputs found
Perception of emotional relationship with parents as the main factor that influence on teen pregnancy in Veracruz
- Author
- Publication venue
- 'Universitat Politecnica de Valencia'
- Publication date
- 01/04/2015
- Field of study
[EN] A qualitative study was conducted in the VIFAC house at Veracruz, Mexico; pregnant
teenagers who attended this institution where interviewed. Based on the data obtained
from the investigation, we observed risk factors that exponentially increased that teenage
girls between 12 and 19 years of age get pregnant, viewed from the perspective of own
teenager. This study was conducted on a sample of 16 participants divided in two
groups, one of pregnant teenagers and one with parent and / or guardian of these, so get
a broader situation of each scenario and to evaluate how each of the factors were
influencing their environment so that pregnancy is arrived at such young age, for which
we apply two types of semi-structured interview depending on the group to which they
belonged.[ES] Se realizó un estudio de carácter cualitativo donde, con base a los datos obtenidos en la investigación, analizamos a fondo los factores de riesgo que elevaron de manera exponencial que adolescentes de entre 12 a 19 años queden embarazadas, vistos desde la perspectiva de la propia adolescente y, de esta manera, obtener un panorama más amplio de la situación de cada adolescente y evaluar cómo cada uno de los factores en su entorno fueron influyendo para que se llegara a un embarazo a tan temprana edad, para lo cual aplicamos una entrevista semiestructurada tanto a adolescentes embarazadas como a sus familiares.Trinidad-Noguera, KI.; Chávez-Montes De Oca, VG.; Carrasco-Ponce, B.; Sánchez-Valdivieso, EA. (2015). Percepción de la relación afectiva con los padres como principal factor que influye sobre el embarazo en adolescentes en Veracruz, México. Revista sobre la infancia y la adolescencia. (8):75-83. doi:10.4995/reinad.2015.3420.SWORD7583
Percepción de la relación afectiva con los padres como principal factor que influye sobre el embarazo en adolescentes en Veracruz, México
- Author
- Publication venue
- Publication date
- 01/01/2015
- Field of study
A qualitative study was conducted in the VIFAC house at Veracruz, Mexico; pregnant teenagers who attended this institution where interviewed. Based on the data obtained from the investigation, we observed risk factors that exponentially increased that teenage girls between 12 and 19 years of age get pregnant, viewed from the perspective of own teenager. This study was conducted on a sample of 16 participants divided in two groups, one of pregnant teenagers and one with parent and / or guardian of these, so get a broader situation of each scenario and to evaluate how each of the factors were influencing their environment so that pregnancy is arrived at such young age, for which we apply two types of semi-structured interview depending on the group to which they belonged.Se realizó un estudio de carácter cualitativo donde, con base a los datos obtenidos en la investigación, analizamos a fondo los factores de riesgo que elevaron de manera exponencial que adolescentes de entre 12 a 19 años queden embarazadas, vistos desde la perspectiva de la propia adolescente y, de esta manera, obtener un panorama más amplio de la situación de cada adolescente y evaluar cómo cada uno de los factores en su entorno fueron influyendo para que se llegara a un embarazo a tan temprana edad, para lo cual aplicamos una entrevista semiestructurada tanto a adolescentes embarazadas como a sus familiares
Reproducibility of fluorescent expression from engineered biological constructs in E. coli
- Author
- Abdirakhmanova Altynay
- Abtahi Kimia
- Acar Muradýye
- Adams David
- Adrian Julia Anna
- Afzal Remsha
- Agarwal Yash
- Ahsan Fasih M.
- Ainsworth Catherine
- Akan Madina
- Aktas Muhammed Fatih
- Al Azhar Muhammad
- Altintas Ali
- Ananda Cindy Suci
- Ananos Mathilde
- Ang Timothy
- Anlind Nils
- Appletion Evan
- Appleton Evan
- Arkhipenko Alexander
- Arroyo María Fernanda Sánchez
- Aruanno Marion
- Asthana Ruchi
- Athale Chaitanya A.
- Aubert Pauline
- Auty Joss
- Ayukawa Shotaro
- Badge Richard
- Bailly Valentin
- Bajorinaite Barbora
- Bali Anne Pihl
- Barrick Jeffrey
- Basier Clovis
- Bastuzel Irem
- Bauerl Christine
- Baumgartner Lisa
- Beal Jacob
- Bech Rasmus
- Bejvl Jan
- Belkhelfa Sophia
- Bender Julian
- Bendorius Mykolas
- Berenger Noemie
- Bermúdez José Alberto Cristerna
- Bestepe Furkan
- Bird Jasmine
- Birk Marlène Sophie
- Birkholz Nils
- Black Lucas
- Bodinier Romain
- Bodkhe Swapnil
- Boralli Camila Maria S
- Bourdarias Johan
- Bramorski Camila Barbosa
- Brasino Michael
- Braun Stefanie
- Brown Bradley
- Bruchez Marcel
- Buchser William
- Bugaud Olivier
- Burlington Todd
- Busche Rudiger Frederik
- Buss Marjorie
- Cadenas Cinthya
- Calendini Daniel
- Calvet Charles
- Canabal Eduardo J Zardain
- Canas-Duarte Silvia
- Cancino-Bernardi Juliana
- Canedo Eduardo Cepeda
- Cantu Claudia Nallely Alonso
- Cantu Mercedes Alejandra Vazquez
- Cao Longzhi
- Caput Jules
- Carrigan Matthew
- Castañeda José Ernesto Hernández
- Castillo Javier
- Ceja Jesus Gilberto Rodriguez
- Ceney Aidan
- Ceyhan Yasemin
- Ceylan Furkan Sacit
- Chabert Yoann
- Chahibi Youssef
- Chambonnier Gael
- Chapet-Batlle Alma
- Chapman Elliott
- Chen An
- Chen Jeffrey
- Chen Jielin
- Chen Yahong
- Chen Yintong
- Chen Zehua
- Chen Zhiqin
- Cherrier Floriane
- Chizzolini Fabio
- Choi Peter
- Choukour Myriam
- Christensen Dallin
- Chu Pan
- Ciesla Anthony
- Cigdem Sadik
- Cigdem Sadýk
- Claassens Nico
- Colloms Sean
- Colls Joshua
- Cook Alexander
- Cordova Cesar Miguel Valdez
- Cottignie Ines
- Craig Sean Ross
- Crawford Liam
- Cruz Ángel Farid Rojas
- Cryan Elli
- Cuillery Emilie
- Czerwinska Urszula
- Dalgleish Raymond
- Davies Sian
- De Bruin Yeshi
- De Ferrante Hans
- De Gaulejac Ella
- De Koster Walter
- De La Paz Espinosa Jose Alberto
- De Lima Ana Laura
- De Mora Kim
- De Vries Andries
- De Wijs Freek
- Del Bianco Cristina
- Demarta-Gatsi Claudia
- Demling Philipp
- Demon-Chaine Coralie
- Deng Changyuan
- Densmore Douglas
- Deprez Eline
- Deryckere Astrid
- DeSanty Kayla
- Devlin Tyler Dae
- Dohan Mikail
- Donauer Julia
- Donovan Michael
- Dowell Robin
- Egholm Anne
- Elbert Rick
- Elitok Mustafa
- Elschot Elles
- Elviantari Adelia
- Emig Ramona
- Esmurria Ariela
- Evans Amy
- Fan Zhao
- Fang Baishan
- Fang Beibei
- Fang Yuxing
- Farny Natalie
- Figueroa María Fernanda Salazar
- Fitriana Maya
- Flynn Charlotte
- Fomitcheva Anna
- Franz Matthias
- Friberg Martin
- Fu Xiaotong
- Fujishima Kosuke
- Gabryelczyk Bartosz
- Gakhare Harsh
- Gamez Eddie Cano
- Gangan Manasi
- Garcia Carlos Enrique Alavez
- Georgiev Daniel
- Gerngross Daniel
- Gershater Markus
- Gertsch Sara
- Giraldo-Perez Daniel
- Glaister Graeme
- Godino Elisa
- Golino Caroline
- Gomez-Garzon Camilo
- Gopaul Deshmukh
- Goss Dan
- Greenberg Danny
- Grundy Cameron
- Gugger Muriel
- Gullberg Erik
- Gunadhi Vivienne
- Gunduz Esra
- Gunduz Mehmet
- Guo Xifeng
- Gursel Mayda
- Gutierrez Alejandro
- Gutierrez Alex
- Gutiérrez Carlos Ramos
- Gómez Daniela Flores
- Haddock-Angelli Traci
- Hakstol Rhys
- Halleran Andrew
- Han Ju Yeon
- Hand Robert
- Hanke Rene
- Hansen Anders Chr
- Hansen Anne Sofie Laerke
- Hanzel Martin
- Hasegawa Takema
- Hatin Isabelle
- Hatipoglu Omer Faruk
- Hawthorne Dakota
- Heng Joseph
- Heredia Ana Laura Navarro
- Herman Stephanie
- Hernandez Adriana
- Hernandez Jesus Eduardo Martinez
- Hernandez Mario Alberto Pena
- Herring Daniel
- Hielkema Lisa
- Ho Jack
- Hollenhorst Jim
- Hoover Benjamin
- Hou Qingfeng
- Houy Camille
- Hua Shuyu
- Huang Tianyi
- Huerta Ana Laura Torres
- Huet-Trujillo Estefania
- Hull Raphaella
- Ikonen Martina
- Iniesta Jorge Sebastián Rodríguez
- Isaacs Farren
- Jackowski Marta Eva
- Jacobs Laura
- Jacobs Taylor
- Jacquot Vincent
- Jacry Cecile
- Jagadeesan Chandhuru
- Jagger Verena
- Janssens Jasper
- Jauregui Sebastian Valdivieso
- Jawale Yash
- Jayawardhana Bayu
- Jensen Kristian
- Jesser Rabea
- Jiang Yue
- Jianguo He
- Jin Yuji
- Jing Zhang
- Jonnaert Frederik
- Ju Tina
- Kadam Snehal
- Kaid-Slimane Ibtissam
- Kang Seong Koo
- Karia Payal
- Karlsen Kristian Barreth
- Kashiwagi Takahiro
- Kasl Hynek
- Kaya Turan
- Kelly Ciaran
- Kent Ryan
- Kerns Timothy
- Khetan Neha
- Kiga Daisuke
- Kizil Burak
- Knoerlein Anna
- Kong Wei Chung
- Konzock Oliver
- Koutsoubelis Nicolas
- Kozakai Tomoya
- Krauss Lucas
- Kronborg Tina
- Kruczko Charlie
- Kuipers Oscar
- Kumru Ilkem
- Kunin Daniel
- Kuvvet Yasemin
- Kyriakakis Phillip
- Lai Dengwen
- LaJeunesse Chloe
- Lale Rahmi
- Lambert Caroline
- Lau Effie
- Lau Kenneth
- Lauxen Anna
- Le Doujet Typhaine
- Lee Donna
- Lee Jenny
- Lee Stephen
- LeFew Michael
- Lei Yiying
- Lentini Roberta
- Levier Axel
- Lewis Kathleen
- Leyva-Hernandez Ariel
- Li Cheng
- Li Jianqiao
- Li Jun
- Li Pai
- Li Xiangkai
- Li Yumeng
- Li Zhe
- Lian Sharon
- Liang Jinyang
- Lieberman Erica
- Lins Paula Maria Pincela
- Lippold Steffen
- Liu Chang
- Liu Jianheng
- Liu Weibing
- Liu Yang
- Lizarazo Meagan
- Loechner Anne C.
- Logger Loreen
- Loke Chun Mun
- Lomeikaite Vilija
- Lona Alonso Pérez
- Lopez Lucia T Estelles
- Lu Li Chieh
- Ludwig Carsten
- Lv Yizhu
- Ma Natalie
- Ma Yu
- Madrid-Wolff Jorge
- Malczewska Katarzyna
- Malone Brandon
- Malsot Paola
- Maniaci Joe
- Mansy Sheref S.
- Mao Stephanie
- Marin-Medina Nathaly
- Marken John
- Marles-Wright Jon
- Marsden Stefan
- Martin Noel Yeh
- Maruyama Haruka
- Matabishi-Bibi Laura
- Mate Seme
- Maxfield Cody
- Mazza Julie
- Mazzanti Valentina
- McCutcheon Griffin
- Meier Michael
- Meijer Thomas
- Meli Rocco
- Mellentine Sam
- Melo Cristiane Casonato
- Mendonca Deborah Cezar
- Meng Xinyu
- Michel Anja
- Miinalainen Tuukka
- Miller Charles
- Miller Dylan
- Minegishi Misa
- Mirzarafie-Ahi Ariana
- Mishler Dennis
- Mishra Yash
- Moatti Audrey
- Moghe Prachiti
- Mohand-Said Sarah
- Monk Jordan
- Montesinos Oliva Angélica Sánchez
- Montiel Eduardo Ramirez
- Morales Eduardo Serna
- Morales Yamile Minerva Castellanos
- Moran Barry
- Moreira Barbara Castro
- Mortensen Kate
- Mosbech Caroline
- Mosqueiro Thiago
- Mous Sandra
- Moynihan Vicky
- Mucha Marlena
- Muller Jan Willem
- Mundhe Gayatri
- Mundt Max
- Naidu Yamini
- Navarro Diana Clarisse Montaño
- Ndiaye Cheikh Fall
- Neumann Julika
- Nguyen Thai
- Ni Chunyang
- Nielsen Chad
- Nin Sebastien
- Ning Kang
- Niyazmetova Luiza
- Nooijens Sjoerd
- O'Hara Samantha
- Olivares Fernanda Sotomayor
- Ono Bruno
- Orakov Askarbek
- Orozco Edgar Alberto Alcalá
- Ospovat Ophir
- Osthege Michael
- Otero Karin
- Owen Liusaidh
- Pacheco Alan
- Paino Ieda Maria Martinez
- Pak Thomas
- Parris Elliott
- Parutto Pierre
- Paskett Michael
- Patil Abha
- Pechotova Katerina
- Peebles Christie
- Pegorar Claudio Oss
- Pei Wan
- Pelisek Vaclav
- Pena Omar Alonso Cantu
- Perez Enrique Amaya
- Peters Danielle
- Petrauskas Arnas
- Pettersen Jens S.
- Phadke Ira
- Philippi Melanie
- Platz Lukas
- Pogoda Cloe Simone
- Poondla Revanth
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- Post Michelle
- Prima Valerie
- Priracha Shaheer
- Prout Luba
- Provan James
- Pulver Cyril
- Putman Ryan
- Pérezávila Juana Yessica
- Qin Qikai
- Quinton Duke
- Radeck Jara
- Ramirez Carlos Alejandro Meza
- Ramirez Rebeca Paola Torres
- Ramirez-Rodríguez Eduardo A.
- Rauluseviciute Ieva
- Raza Sikandar
- Reddy Sanjana
- Rettberg Randy
- Ribovski Lais
- Richter Alexandra
- Richter Felix
- Rifei Chen
- Robben Johan
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- Rocha Tyler
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- Sayin Orhan
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- Schepers Otto
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- Sebastian Mariola
- Shattuck Kendra
- Shaykevich Daniel
- Shi Yuanjie
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- Shilts Jarrod
- Shin Nathan
- Shinohara Riku
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- Silva Juan Carlos Rueda
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- Slack Joseph
- Smith Dustin
- Smith Olivia
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- Song Xinhao
- Sosnova Anna
- Spencer-Milnes Xenia
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- Steijl Barbara
- Steiner Loic
- Steininger Victor
- Stuhn Lara
- Sturgis James N.
- Su Yetian
- Su Yue
- Sudarsan Suresh
- Sun Libo
- Takahashi Jack
- Tang Chun
- Tang Shuyan
- Tangirala Sivateja
- Tapan Safa
- Teague Brian
- Telmer Cheryl
- Tercan Helin
- Tereci Osman Faruk
- Thavarajah Walter
- Thirukkumaran Ovia Margaret
- Thompson Kirsten
- Thouvenin Gregoire
- Timmons Joshua
- Tingley Jeff
- Tokuma Hiraku
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- Tran Forrest
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- Turland Alex
- Tye Chelsey
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- Uniyal Prashant
- Uran Axel
- Urick David
- Uçar Abdullah
- Vaassen Femke
- Van Der Does Marit
- Van Der Putten Cas
- Van Deuren Vincent
- Van Hese Laura
- Van Leeuwen Esther
- Van Raaphorst Renske
- Van Rijn Erwin
- Van Rosmalen Rik
- Van Smeden Laura
- Van Tiel Nina
- Van Wonterghem Laetitia
- Van't Hof Max
- Vandebroek Laurens
- Vandendaele Amelie
- Vasconcelos Graziele
- Vazquez Claudia Melissa Guerra
- Veening Jan Willem
- Verschooten Leen
- Vij Panya
- Vilar Marta Vazquez
- Viola John
- Von Chamier Lucas
- Von Kügelgen Nicolai
- Wadhams George
- Wahab Adam
- Walsh Kevin
- Wang Boxiang
- Wang Haotian
- Wang Lena
- Wang Weiyi
- Wang Xuan
- Wang Yingqi
- Wang Yushen
- Watkins Ella
- Weber Susanne
- Wehle Devin
- Wehrs Maren
- Wei Huang
- Wei Yang
- Wei Yibing
- Wellinger Lisa
- Wellman Rachel
- Weme Ruud Detert Oude
- Werchau Niels
- Westwood Georgina
- Wieden Hans Joachim
- Wieske Lianne
- Witarto Arief Budi
- Wojcik Emilia
- Wolter Moritz
- Wronska Anna
- Wu Fan
- Wu Guozhao
- Wu Qi
- Wu Wen Ying
- Xiang Daniel
- Xiangyue Hu
- Xiaojing Li
- Xiaomei Lin
- Xiaoran Yang
- Xu Zixuan
- Xunxun Luo
- Yamazaki Yuta
- Yan Jieyu
- Yan Keji
- Yan Ming
- Yan Xiaoshan
- Yang Kang
- Yang Yang
- Yang Yunjun
- Yao Ningning
- Yasunishi Shuhei
- Yen Zen Zen
- Yilmaz Mustafa
- Ying Oscar
- Young Hannah
- Young Paul
- Yousaf Waqar
- Yu Michelle
- Yuanzhan Yang
- Yuksel Seniz
- Yulianti
- Yushan Zhang
- Zach Pavel
- Zadey Siddhesh
- Zampronio Danilo Keiji
- Zaworski Julie
- Zeng Zhi
- Zhailauova Azhar
- Zhan Yi
- Zhang Haoqian Myelin
- Zhang Qianbin
- Zhang Ruihua
- Zhang Tangduo
- Zhang Zhaoran
- Zhao Hongxia
- Zhao Ruixue
- Zhaosen Wen
- Zhou Yineng
- Zhu Iowis
- Zhu Kwan Kwan
- Zimmermann Arne
- Zimont Allison
- Zixuan Erinn Sim
- Ávila Alejandro Gómez
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/03/2016
- Field of study
We present results of the first large-scale interlaboratory study carried out in synthetic biology, as part of the 2014 and 2015 International Genetically Engineered Machine (iGEM) competitions. Participants at 88 institutions around the world measured fluorescence from three engineered constitutive constructs in E. coli. Few participants were able to measure absolute fluorescence, so data was analyzed in terms of ratios. Precision was strongly related to fluorescent strength, ranging from 1.54-fold standard deviation for the ratio between strong promoters to 5.75-fold for the ratio between the strongest and weakest promoter, and while host strain did not affect expression ratios, choice of instrument did. This result shows that high quantitative precision and reproducibility of results is possible, while at the same time indicating areas needing improved laboratory practices.Peer reviewe
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- Abellán Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Akçay Özlem
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia González
- Aleem Muhammad
- Alegre Inês
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz Amorós
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-Díez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
- Amado Fabíola
- Amador Cristina García
- Amanullah Nazli
- Amaral Hélida Aline Tomacheski
- Amaral Luis
- Amin-Tai Hizami
- Aminu Bashiru
- Amir Ahmad Suhaimi
- Ammar Ahmed Siddique
- Ammar Mona Ahmed
- Ammendola Michele
- Ammerata Giorgio
- Amorim Edgar
- Ancans Guntis
- Anderson Tom
- Andrade Diogo
- Andrejevic Predrag
- Andrés Beatriz Díaz San
- Anestiadou Elissavet
- Ang Chin Wee
- Angelo Franceschi
- Anokhin Evgeny
- Anoldo Pietro
- Antakia Ramez
- Anton Majd
- Antonelli Serena
- Antropoli Carmine
- Anula Rocio
- Anwar Jamal
- Anyadike Florence
- Apostolakidou Magda
- Apostolidi Eirini
- Aprea Giovanni
- Arabadzhiev Angel
- Arakawa Satoshi
- Arauz Jazmin
- Aravindan U
- Aremu Abdurrahman
- Aremu Isiaka
- Argawy Osama
- Arican Can
- Arida Zahed Abu
- Armellin Claudia
- Arnaoutoglou Eleni
- Arreguy-Borges Kanthya
- Artigot Mariano
- Arturi Alessandro
- Arulappan Nirupama
- Arya Shobhit
- Arynov Ardak
- Asaad Peter
- Asano Yukio
- Ascari Francesca
- Asgarov Mohsum
- Ashmawy Soad
- Aslam Muhammad Imran
- Assimakopoulou Elena
- Assis Ana
- Astilleta Romina
- Atanasov Boyko
- Atendido Tiffany
- Athanasakis Elias
- Atici Semra Demirli
- Avellaneda Nicholas
- Avellaneda Nicolas
- Avseren Goksu
- Awead Marwa
- Ayandipo Omobolaji
- Aybar Engin
- Aydin Funda
- Aydin Gaye
- Ayoub Kusay
- Aytac Erman
- Aytaç Erman
- Azevedo Jose
- Azevedo Patricia
- Azhar Najia
- Aziz Gowhar
- Azman Zairul Azwan Mohd
- Aşkar Ahmet
- Babatunde Olanrewaju
- Badawi Marwa
- Baek Jeong-Heum
- Baez Noelia Fernández
- Baeza-Murcia Melody
- Bagnardi Francesco
- Baharom Salahudin
- Baik Seung Hyuk
- Baimakhanov Abylai
- Bains Lovenish
- Baker Aleksandra
- Bakmaz Bernarda
- Bala Abubakar Muhammad
- Balaban Vladimir
- Balalis Dimitrios
- Balasubramaniam Dinesh
- Balathayalan Yathev
- Baldi Claudio
- Balestri Riccardo
- Balfour James
- Ballah Abubakar
- Ballian Nikiforos
- Balooshi Iman Al
- Baloyiannis Ioannis
- Bamford Richard
- Bandar Mahdi Al
- Banham Gail
- Bannoud Mohammad Hassan
- Baptista Victor
- Baral Jörg
- Barbalace Nicolas
- Barbato Giuseppe
- Barbosa Anderson
- Bareka Metaxia
- Baris Baver
- Barradas Renato
- Barreda Sara Castillo
- Barrena-Blazquez Silvestra
- Barton Jess
- Bartosiak Katarzyna
- Bashilkina Olga
- Bashir Mohammed
- Basile Raffaele
- Basnyat Pradeep
- Batool Sana
- Bautista Wilson Manuel Sánchez
- Bayhan Zülfü
- Bayo José Manuel Muros
- Bayón Raquel Álvaro
- Baños Pedro Antonio Parra
- Beard David
- Bedzhanyan Arkady
- Behilil Chakib
- Bekele Kebebe
- Belarmino Armin
- Belay Million
- Belev Nikolay
- Bellato Vittoria
- Beltrán de Heredia Juan
- Belvedere Angela
- Benetti Emilio
- Benetti Sara
- Bengueddach Aicha
- Benjelloun El Bachir
- Benkabbou Amine
- Bennett James
- Bensafir Salim
- Bergamini Carlo
- Bernotaite Vlada
- Beron Reinaldo Isaacs
- Bethune Robert
- Bezede Cosmin
- Beznosenko Andriy
- Bhangu Aneel
- Bhargava Aman
- Bhat Rama Rani Krishna
- Bianchi Romina
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- Zaari Fatimazahraa
- Zabiyaka Mikhail
- Zadrożna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
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- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
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- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah Kağan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Álvarez-Llano Laura
- Ângelo Miguel Duarte
- ÓSullivan Sara Nuñez
- Özçelik Mehmet Faik
- Ćoza Ivo
- Şanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)