Severa complicación neurológica tras vertebroplastia percutánea

La vertebroplastia percutánea como tratamiento de las fracturas acuñamientos vertebrales osteoporóticos tras fracaso del tratamiento sintomático y ortopédico así como para el tratamiento de lesiones tumorales del caquis ha tomado un auge importante debido a los buenos resultados publicados y la baja tasa de complicaciones. Este hecho ha llevado a las casas comerciales a desarrollar productos específicos para esta técnica que simplifican su utilización y disminuyen en lo posible las dificultades técnicas del procedimiento así como sus complicaciones. A pesar de ello, en nuestra opinión es una técnica que requiere una alta demanda de entrenamiento y que puede dar lugar a graves complicaciones a pesar de que no existan prácticamente en la literatura complicaciones severas con la utilización de esta técnica. Presentamos un caso ocurrido en nuestra serie de una paraplejia completa no resuelta tras una vertebroplastia percutanea torácica para una fractura osteoporótica.The technique of percutaneous vertebroplasty for osteoporotic fractures and spine tumors was develop an important increase because there were a lot of publications with good results and low rate of complications. This fact was done a fast developing of instruments and new PMMA cements to simplify this technique and decreased the rate of complications. In our opinion the percutaneous vertebroplasty is a high demand technique and have a high potential of major neurological complications if it is not performed with use of appropriate safeguards, but the purpose of this article is not to condemn the technique because we have had a good results using it in this pathologies and the majority of publications have shown a high rate of excellent results

Optimized sound diffusers based on sonic crystals using a multiobjective evolutionary algorithm

Sonic crystals have been demonstrated to be good candidates to substitute for conventional diffusers in order to overcome the need for extremely thick structures when low frequencies have to be scattered, however, their performance is limited to a narrow band. In this work, multiobjective evolutionary algorithms are used to extend the bandwidth to the whole low frequency range. The results show that diffusion can be significantly increased. Several cost functions are considered in the paper, on the one hand to illustrate the flexibility of the optimization and on the other hand to demonstrate the problems associated with the use of certain cost functions. A study of the robustness of the optimized diffusers is also presented, introducing a parameter that can help to choose among the best candidates. Finally, the advantages of the use of multiobjective optimization in comparison with conventional optimizations are discussed.This work was partially supported by the Spanish "Ministerio de Economia y Competitividad" under the projects TEC2015-68076-R and DPI2015-71443-R.Redondo, J.; Sánchez Pérez, JV.; Blasco, X.; Herrero Durá, JM.; Vorlander, M. (2016). Optimized sound diffusers based on sonic crystals using a multiobjective evolutionary algorithm. Journal of the Acoustical Society of America. 139(5):2807-2814. doi:10.1121/1.4948580S28072814139

Acoustic behavior of the VEGA launch pad environment

[EN] The acoustic pressure levels experienced by the spacecraft and launchers during the lift-off is due among other factor by the reflection of the sound waves on the launch pad. The acoustic load distribution in the area of the launcher depends on the geometric, mechanical and acoustic characteristics of the ground facilities. This work is intended to study the acoustic environment of the launch pad. A numerical and experimental investigation is developed in order to study in the linear regime the acoustic behaviour of a subscale model of the VEGA's launch pad. The acoustic measurements are performed in an anechoic chamber using an electroacoustic source that emits incoherent noise, mimicking the real acoustic source. The acoustic pressure field is measured at different positions in front of the launch pad mock-up, in the area where the acoustic waves are reflected. Among the future perspectives of this work is to study and develop new methods for the mitigation of the sound pressure levels.Authors acknowledge the support of the European Space Agency under contract ¿Sonic Crystals For Noise Reduction At The Launch Pad¿ ESA ITT 1-7094 (ITI) and the 441-2015 Co-Sponsered PhD ¿Acoustic Reduction Methods for the Launch Pad¿. The work was supported by Spanish Ministry of Economy and Innovation (MINECO) and European Union FEDER through project FIS2015-65998-C2-2. Authors aknowledge Dhéric Mutel, Cyril Bernard and Clément Jost for their contribution to this workPicó Vila, R.; Herrero-Durá, I.; Sánchez Morcillo, VJ.; Salmerón-Contreras, LJ.; García-Raffi, LM. (2016). Acoustic behavior of the VEGA launch pad environment. Universidade do Porto. 1-6. http://hdl.handle.net/10251/181097S1

Coupling carbon nanotube mechanics to a superconducting circuit

The quantum behaviour of mechanical resonators is a new and emerging field driven by recent experiments reaching the quantum ground state. The high frequency, small mass, and large quality-factor of carbon nanotube resonators make them attractive for quantum nanomechanical applications. A common element in experiments achieving the resonator ground state is a second quantum system, such as coherent photons or superconducting device, coupled to the resonators motion. For nanotubes, however, this is a challenge due to their small size. Here, we couple a carbon nanoelectromechanical (NEMS) device to a superconducting circuit. Suspended carbon nanotubes act as both superconducting junctions and moving elements in a Superconducting Quantum Interference Device (SQUID). We observe a strong modulation of the flux through the SQUID from displacements of the nanotube. Incorporating this SQUID into superconducting resonators and qubits should enable the detection and manipulation of nanotube mechanical quantum states at the single-phonon level

Simultaneous detection of the three ilarviruses affecting stone fruit trees by nonisotopic molecular hybridization and multiplex reverse-transcription polymerase chain reaction

[EN] The three most economically damaging ilarviruses affecting stone fruit trees on a worldwide scale are the related Prunus necrotic ringspot virus (PNRSV), Prune dwarf virus (PDV), and Apple mosaic virus (ApMV). Nonisotopic molecular hybridization and multiplex reverse-transcription polymerase chain reaction (RT-PCR) methodologies were developed that could detect all these viruses simultaneously. The latter technique was advantageous because it was discriminatory. For RT-PCR, a degenerate antisense primer was designed which was used in conjunction with three virus-specific sense primers. The amplification efficiencies for the detection of the three viruses in the multiplex RT-PCR reaction were identical to those obtained in the single RT-PCR reactions for individual viruses. This cocktail of primers was able to amplify sequences from all of the PNRSV, ApMV, and PDV isolates tested in five Prunus spp. hosts (almond, apricot, cherry, peach, and plum) occurring naturally in single or multiple infections. For ApMV isolates, differences in the electrophoretic mobilities of the PCR products were observed. The nucleotide sequence of the amplified products of two representative ApMV isolates was determined, and comparative analysis revealed the existence of a 28-nucleotide deletion in the sequence of isolates showing the faster electrophoretic mobility. To our knowledge, this is the first report on the simultaneous detection of three plant viruses by multiplex RT-PCR in woody hosts. This multiplex RT-PCR could be a useful time and cost saving method for indexing these three ilarviruses, which damage stone fruit tree yields, and for the analysis of mother plants in certification programs.We thank Drs. P.H. Berger and P.J. Shield for providing the ApMV clone and Dr. S. Scott for the PDV clone. We also thank P. Thomas and M.W. van der Heidjen for help with the English version of the manuscript. This work was supported by grant BIO99-0854 from the Spanish granting agency DGICYT. F.A. and J.A. S-N. were the recipients of fellowships from the Ministerio de Educacion y Cultura of Spain. M. S. was supported by the Italian Ministry of Foreign Affairs and CIHEAM/IAMB.Saade, M.; Aparicio Herrero, F.; Sánchez-Navarro, JA.; Herranz Gordo, MC.; Myrta, A.; Di Terlizzi, B.; Pallás Benet, V. (2000). Simultaneous detection of the three ilarviruses affecting stone fruit trees by nonisotopic molecular hybridization and multiplex reverse-transcription polymerase chain reaction. Phytopathology. 90(12):1330-1336. https://doi.org/10.1094/PHYTO.2000.90.12.133013301336901

The nuclear and extended infrared emission of the Seyfert galaxy NGC 2992 and the interacting system Arp 245

We present subarcsecond resolution infrared (IR) imaging and mid-IR spectroscopic observations of the Seyfert 1.9 galaxy NGC 2992, obtained with the Gemini North Telescope and the Gran Telescopio CANARIAS (GTC). The N-band image reveals faint extended emission out to ~3 kpc, and the PAH features detected in the GTC/CanariCam 7.5-13 micron spectrum indicate that the bulk of this extended emission is dust heated by star formation. We also report arcsecond resolution MIR and far-IR imaging of the interacting system Arp 245, taken with the Spitzer Space Telescope and the Herschel Space Observatory. Using these data, we obtain nuclear fluxes using different methods and find that we can only recover the nuclear fluxes obtained from the subarcsecond data at 20-25 micron, where the AGN emission dominates. We fitted the nuclear IR spectral energy distribution of NGC 2992, including the GTC/CanariCam nuclear spectrum (~50 pc), with clumpy torus models. We then used the best-fitting torus model to decompose the Spitzer/IRS 5-30 spectrum (~630 pc) in AGN and starburst components, using different starburst templates. We find that, whereas at shorter mid-IR wavelengths the starburst component dominates (64% at 6 micron), the AGN component reaches 90% at 20 micron. We finally obtained dust masses, temperatures and star formation rates for the different components of the Arp 245 system and find similar values for NGC 2992 and NGC 2993. These measurements are within those reported for other interacting systems in the first stages of the interaction.Comment: 20 pages, 12 figures, accepted by MNRA

Thioredoxin Domain Containing 5 Suppression Elicits Serum Amyloid A-Containing High-Density Lipoproteins

Thioredoxin domain containing 5 (TXNDC5) is a protein disulfide isomerase involved in several diseases related to oxidative stress, energy metabolism and cellular inflammation. In a previous manuscript, a negative association between fatty liver development and hepatic Txndc5 expression was observed. To study the role of TXNDC5 in the liver, we generated Txndc5-deficient mice. The absence of the protein caused an increased metabolic need to gain weight along with a bigger and fatter liver. RNAseq was performed to elucidate the putative mechanisms, showing a substantial liver overexpression of serum amyloid genes (Saa1, Saa2) with no changes in hepatic protein, but discrete plasma augmentation by the gene inactivation. Higher levels of malonyldialdehyde, apolipoprotein A1 and platelet activating factor-aryl esterase activity were also found in serum from Txndc5-deficient mice. However, no difference in the distribution of high-density lipoproteins (HDL)-mayor components and SAA was found between groups, and even the reactive oxygen species decreased in HDL coming from Txndc5-deficient mice. These results confirm the relation of this gene with hepatic steatosis and with a fasting metabolic derive remedying an acute phase response. Likewise, they pose a new role in modulating the nature of HDL particles, and SAA-containing HDL particles are not particularly oxidized. © 2022 by the authors. Licensee MDPI, Basel, Switzerland

Experimental Feeding and Growth of Turbot (Scophthalmus maximus L.) from 0.5 To 2.7 Kg in Galicia (NW Spain)

Two groups of turbot, Scophthalmus maximus L., of 0.5 and 1.2 kg initial mean weight were fed a semimoist diet containing fish, fish meal and vitamin-mineral complex. The trial was carried out in tanks of 16 cubic meters, for aperiod of a year. Resul ts on feed conversion index and growth in weight are give