15 research outputs found
Compliance with current dietary recommendations and geographical variability of diet in women participating in 7 screening programs for breast cancer in Spain
Introducción: Una dieta saludable es especialmente
importante durante la menopausia, periodo en el que
aumenta el riesgo de varios problemas de salud. Analizamos
la dieta de mujeres peri y postmenopáusicas españolas
y el grado de cumplimiento de las recomendaciones
actuales.
Material y métodos: Estudio transversal en 3.574 mujeres
de 45-68 años que acuden al cribado de cáncer de
mama en 7 centros (A Coruña, Barcelona, Burgos, Palma
de Mallorca, Pamplona, Valencia y Zaragoza). Se recogió
la dieta mediante un cuestionario de frecuencia de alimentos
validado para población española. Para la valoración
del cumplimiento de las recomendaciones actuales se
utilizaron los rangos recomendados por la Sociedad
Española de Nutrición Comunitaria para ingesta de grupos
de alimentos y las Ingestas Diarias Recomendadas
(IDR) para energía, vitaminas y minerales de la Federación
Española de Nutrición, Alimentación y Dietética.
Resultados: El 29% de las mujeres eran obesas y un
42% tenía sobrepeso. El aporte calórico medio fue de
2.053 kcal (DE: 480). El perfil calórico general fue de:
43% de la energía aportada por lo carbohidratos, 36%
por las grasas, 20% por las proteínas. Se evidenció una
ingesta deficiente de vitamina D en todos los nodos del
estudio, con una ingesta media general de 2,14 μg/día. Se
detectó a su vez una ingesta deficitaria de vitamina E en A
Coruña y Burgos. Todos los centros presentaron una
ingesta elevada de productos lácteos y de legumbres. El
consumo de frutas y verduras fue muy heterogéneo
siendo especialmente elevada su ingesta en Mallorca y
Valencia mientras que fue baja para ambos grupos de alimentos
en A Coruña. La ingesta de aceite de oliva fue elevada
en todos los centros exceptuando Burgos con un
74,3% de las mujeres estudiadas por debajo de las 3
raciones al día recomendadas.
Conclusiones: Una dieta con menos grasas y proteínas
y más rica en vegetales, frutos secos y alimentos ricos en
hidratos de carbono equilibraría el balance energético y
mejoraría la calidad de la dieta corrigiendo las bajas
ingestas de vitaminas D y E. Estas recomendaciones son
especialmente importantes en las ciudades más alejadas
de la costa mediterránea donde se han detectado mayores
incumplimientos de las recomendaciones vigentes y una
dieta más alejada de la dieta mediterránea.Introduction: A healthy diet is especially important
during menopause, a period which increases the risk of
various health problems. We analyzed the diet of periand
postmenopausal Spanish women and the degree of
compliance with current recommendations.
Material and methods: We studied 3574 women 45-68
years old who attended breast cancer screening programmes
in 7 centres (A Coruña, Barcelona, Burgos,
Palma de Mallorca, Pamplona, Valencia and Zaragoza).
Diet information was collected using a food frequency
questionnaire validated for the Spanish population. For
the assessment of compliance with current guidelines we
used the recommendations by the Spanish Society of
Community Nutrition for food groups intake and by the
Spanish Federation of Nutrition, Food and Dietetics for
energy, vitamins and minerals intake.
Results: The 29% of women were obese and 42% overweight.
The average caloric intake was 2.053 kcal (SD
480). The general energy profile was: 43% of the energy
from the carbohydrates, 36% from fats, and 20% from
proteins. There was a low vitamin D intake in all centres
of the study, with an overall mean intake of 2.14 mg/day.
A deficit of vitamin E intake in A Coruña and Burgos was
also detected. Intake of dairy products and vegetables
was high in all the study centers. The consumption of
fruits and vegetables was very heterogeneous, with high
intakes observed in Mallorca and Valencia and low for
both food groups in A Coruña. The olive oil intake was
high in all centers except Burgos with 74.3% of the
women studied below the recommended 3 servings per
day.
Conclusions: A diet with less fat and protein and a
higher consumption of vegetables, nuts and foods rich in
carbohydrate might balance the energy intake and
improve the quality of the diet correcting the low intakes
of vitamins D and E. These recommendations are especially
important in cities far from the Mediterranean
coast where more breaches have been detected over the
current recommendations with a lower adherence to the
Mediterranean diet.Este estudio ha recibido financiación del Fondo de
Investigación Sanitaria (proyecto PI060386) y de
Astra-Zéneca (convenio de colaboración entre Astra-
Zeneca y el Instituto de salud Carlos III 1306-1306
EPY
Compliance with current dietary recommendations and geographical variability of diet in women participating in 7 screening programs for breast cancer in Spain.
[ES] Introducción:Una dieta saludable es especialmenteimportante durante la menopausia, periodo en el queaumenta el riesgo de varios problemas de salud. Analiza-mos la dieta de mujeres peri y postmenopáusicas españo-las y el grado de cumplimiento de las recomendacionesactuales. Material y métodos:Estudio transversal en 3.574 muje-res de 45-68 años que acuden al cribado de cáncer demama en 7 centros (A Coruña, Barcelona, Burgos, Palmade Mallorca, Pamplona, Valencia y Zaragoza). Se recogióla dieta mediante un cuestionario de frecuencia de ali-mentos validado para población española. Para la valora-ción del cumplimiento de las recomendaciones actuales seutilizaron los rangos recomendados por la SociedadEspañola de Nutrición Comunitaria para ingesta de gru-pos de alimentos y las Ingestas Diarias Recomendadas(IDR) para energía, vitaminas y minerales de la Federa-ción Española de Nutrición, Alimentación y Dietética. Resultados:El 29% de las mujeres eran obesas y un42% tenía sobrepeso. El aporte calórico medio fue de2.053 kcal (DE: 480). El perfil calórico general fue de: 43% de la energía aportada por lo carbohidratos, 36%por las grasas, 20% por las proteínas. Se evidenció unaingesta deficiente de vitamina D en todos los nodos delestudio, con una ingesta media general de 2,14 μg/día. Sedetectó a su vez una ingesta deficitaria de vitamina E en ACoruña y Burgos. Todos los centros presentaron unaingesta elevada de productos lácteos y de legumbres. Elconsumo de frutas y verduras fue muy heterogéneosiendo especialmente elevada su ingesta en Mallorca yValencia mientras que fue baja para ambos grupos de ali-mentos en A Coruña. La ingesta de aceite de oliva fue ele-vada en todos los centros exceptuando Burgos con un74,3% de las mujeres estudiadas por debajo de las 3raciones al día recomendadas. Conclusiones:Una dieta con menos grasas y proteínasy más rica en vegetales, frutos secos y alimentos ricos enhidratos de carbono equilibraría el balance energético ymejoraría la calidad de la dieta corrigiendo las bajasingestas de vitaminas D y E. Estas recomendaciones sonespecialmente importantes en las ciudades más alejadasde la costa mediterránea donde se han detectado mayoresincumplimientos de las recomendaciones vigentes y unadieta más alejada de la dieta mediterránea.
[EN] A healthy diet is especially important during menopause, a period which increases the risk of various health problems. We analyzed the diet of periand postmenopausal Spanish women and the degree of compliance with current recommendations.
We studied 3574 women 45-68 years old who attended breast cancer screening programmes in 7 centres (A Coruña, Barcelona, Burgos, Palma de Mallorca, Pamplona, Valencia and Zaragoza). Diet information was collected using a food frequency questionnaire validated for the Spanish population. For the assessment of compliance with current guidelines we used the recommendations by the Spanish Society of Community Nutrition for food groups intake and by the Spanish Federation of Nutrition, Food and Dietetics for energy, vitamins and minerals intake.
The 29% of women were obese and 42% overweight. The average caloric intake was 2.053 kcal (SD 480). The general energy profile was: 43% of the energy from the carbohydrates, 36% from fats, and 20% from proteins. There was a low vitamin D intake in all centres of the study, with an overall mean intake of 2.14 mg/day. A deficit of vitamin E intake in A Coruña and Burgos was also detected. Intake of dairy products and vegetables was high in all the study centers. The consumption of fruits and vegetables was very heterogeneous, with high intakes observed in Mallorca and Valencia and low for both food groups in A Coruña. The olive oil intake was high in all centers except Burgos with 74.3% of the women studied below the recommended 3 servings per day.
A diet with less fat and protein and a higher consumption of vegetables, nuts and foods rich in carbohydrate might balance the energy intake and improve the quality of the diet correcting the low intakes of vitamins D and E. These recommendations are especially important in cities far from the Mediterranean coast where more breaches have been detected over the current recommendations with a lower adherence to the Mediterranean diet.Este estudio ha recibido financiación del Fondo deInvestigación Ssanitaria (proyecto PI060386) y de Astra-Zéneca (convenio de colaboración entre Astra-Zeneca y el Instituto de salud Carlos III 1306-1306EPY).S
Determinants of non attendance to mammography program in a region with high voluntary health insurance coverage
<p>Abstract</p> <p>Background</p> <p>High participation rates are needed to ensure that breast cancer screening programs effectively reduce mortality. We identified the determinants of non-participation in a public breast cancer screening program.</p> <p>Methods</p> <p>In this case-control study, 274 women aged 50 to 64 years included in a population-based mammography screening program were personally interviewed. Socio-demographic characteristics, health beliefs, health service utilization, insurance coverage, prior mammography and other preventive activities were examined.</p> <p>Results</p> <p>Of the 192 cases and 194 controls contacted, 101 and 173, respectively, were subsequently interviewed. Factors related to non-participation in the breast cancer screening program included higher education (odds ratio [OR] = 5.28; 95% confidence interval [CI95%] = 1.57–17.68), annual dental checks-ups (OR = 1.81; CI95%1.08–3.03), prior mammography at a private health center (OR = 7.27; CI95% 3.97–13.32), gynecologist recommendation of mammography (OR = 2.2; CI95%1.3–3.8), number of visits to a gynecologist (median visits by cases = 1.2, versus controls = 0.92, P = 0.001), and supplemental private insurance (OR = 5.62; CI95% = 3.28–9.6). Among women who had not received a prior mammogram or who had done so at a public center, perceived barriers were the main factors related to non-participation. Among women who had previously received mammograms at a private center, supplemental private health insurance also influenced non-participation. Benign breast symptoms increased the likelihood of participation.</p> <p>Conclusion</p> <p>Our data indicate that factors related to the type of insurance coverage (such as prior mammography at a private health center and supplemental private insurance) influenced non-participation in the screening program.</p
Validity and acceptance of self vs conventional sampling for the analysis of human papillomavirus and Pap smear
Abstract The newest high-risk human papillomavirus (HPV) detection techniques were included for cervical cancer primary screening under the Spanish National Health System in 2019. These analyses allow changing population approaches to foster adherence to screening. Therefore, the validity of self versus conventional sampling for HPV and cytology analyses was appraised. Women's preferences concerning samples and devices were also evaluated. This is a diagnostic accuracy cross-sectional study among 120 women recruited from a colposcopy clinic at a general hospital in Illes Balears, Spain. Participants were given written information and asked for a self-sample. One of two sets containing two devices each were handed. One set was transported dry and the second in liquid medium. Next, clinicians collected vaginal samples that were our gold standards. The agreement between both techniques was examined with the Kappa coefficient (κ). Self-sampling evaluation and preferences for different vaginal devices were also surveyed. The agreement between self and conventional samples concerning HPV positivity was very good (κ 0.86 for Mía by XytoTest® and 0.83 for Viba-Brush®) or reasonable (κ 0.73 for Iune and 0.68 for viscose swab). Pap smears from self-samples exhibited moderate agreement (κ 0.41 for Mía® and 0.51 for Viba-Brush® respectively) for negative versus ASC-US and worse results. Most of the participants considered self-sampling as beneficial (110 or 91.7%) and the advantages were, in decreasing order, scheduling, comfort, intimacy and less fear for pain or disturbance. The priority of choice for the devices was Mía® and viscose swab (chosen in first or second place) in opposition to Iune and Viba-Brush® (chosen in third or fourth place). If Viba-Brush® was to collect the best quality samples, 108 women (94.7%) switched their decisions. Our agreement between self and conventional samples was very good or reasonable for HPV, with the best values for devices in a liquid medium, and moderate for cytology. Even so, reflex cytology on self-samples is a valuable tool in promoting adherence. Self-sampling was widely accepted for smooth and thin devices. However, there is no resistance to change to others if a higher quality of the sample is obtained
Genome wide association study identifies a novel putative mammographic density locus at 1q12-q21.
Mammographic density (MD) is an intermediate phenotype for breast cancer. Previous studies have identified genetic variants associated with MD; however, much of the genetic contribution to MD is unexplained. We conducted a two-stage genome-wide association analysis among the participants in the "Determinants of Density in Mammographies in Spain" study, together with a replication analysis in women from the Australian MD Twins and Sisters Study. Our discovery set covered a total of 3,351 Caucasian women aged 45 to 68 years, recruited from Spanish breast cancer screening centres. MD was blindly assessed by a single reader using Boyd's scale. A two-stage approach was employed, including a feature selection phase exploring 575,374 SNPs in 239 pairs of women with extreme phenotypes and a verification stage for the 183 selected SNPs in the remaining sample (2,873 women). Replication was conducted in 1,786 women aged 40 to 70 years old recruited via the Australian Twin Registry, where MD were measured using Cumulus-3.0, assessing 14 SNPs with a p value <0.10 in stage 2. Finally, two genetic variants in high linkage disequilibrium with our best hit were studied using the whole Spanish sample. Evidence of association with MD was found for variant rs11205277 (OR = 0.74; 95% CI = 0.67-0.81; p = 1.33 × 10(-10) ). In replication analysis, only a marginal association between this SNP and absolute dense area was found. There were also evidence of association between MD and SNPs in high linkage disequilibrium with rs11205277, rs11205303 in gene MTMR11 (OR = 0.73; 95% CI = 0.66-0.80; p = 2.64 × 10(-11) ) and rs67807996 in gene OTUD7B (OR = 0.72; 95% CI = 0.66-0.80; p = 2.03 × 10(-11)). Our findings provide additional evidence on common genetic variations that may contribute to MD.Work was partially supported by project from the Spanish MINECO (BIO2009–12458).S