307 research outputs found

    Datos para el estudio de la región hullera de la provincia de Burgos

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    Separata de: Boletín del Instituto Geológico de EspañaTít. del mapa: Bosquejo geológico de la región hullera de la provincia de BurgosCopia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 201

    El alumbramiento de aguas, practicado en el término de Nebreda para el abastecimiento de la villa de Lerma en la provincia de Burgos

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    Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-2010Separat

    Sondeo en el extremo oriental de la cuenca carbonífera de Guardo (Palencia)

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    Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-2010Separata de: Boletín del Instituto Geológico de España, t. 33 (1912

    Francesc Xavier Balmis: ciutadà del món

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    L'alacantí Francesc Xavier Balmis i Berenguer i el barceloní Josep Salvany Lleopart van ser els protagonistes, el 1803, d'una expedició a Amèrica i Filipines per portar la vacuna de la verola a territoris on aquesta epidèmia provocava alts índexs de mortalitat. Dos-cents anys després, tres professors de la Universitat d'Alacant analitzen la importància d'aquella expedició

    Ejemplo de la utilidad de Internet para la enseñanza especializada universitaria

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    Se analizan en este artículo distintas posibilidades de la red Internet para completar la formación de los estudiantes universitarios en nuestros centros. En concreto se muestran una serie de informaciones relativas a la Administración de Sistemas Informáticos que habrían sido imposible recoger de otro modo, ante la escasez de bibliografía sobre el tema. Si a esto añadimos que dicha información afecta a la seguridad de los sistemas informáticos, que es justo la tarea prioritaria de los diplomados en este módulo, se comprende la importancia transcendental de la incorporación de estas nueva tecnología de comunicación a nuestra formación.This item analyses the different ways in which the Internet network can be used to complete the education of University students at our centres. It specifically divulges information related to Computer Systems Management that would not have been possible to collect through any other means due to the lack of bibliography concerning this issue. If we also add that this information affects computer system security which is exactly the main task of the graduate students included in this module , one understands the transcendental importance of incorporating this new media technology to our training

    Artichoke By-Products as Natural Source of Phenolic Food Ingredient

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    Nowadays, the transformation activity of the food industry results in the generation of a huge amount of daily discarded vegetables wastes. One of those undervalued by-products are produced during the post-harvesting and processing process of artichokes. In the present research, the potential of artichokes’ bracts and stalks have been evaluated as a natural source of phenolic compounds which could be used as bioactive food ingredients, among others. In this study, the bioactive composition of those wastes has been evaluated using recent advances in extraction and analytical technologies, concretely, pressurized liquid extraction (PLE) followed by high-performance liquid chromatography (HPLC) coupled to electrospray time-of flight mass spectrometry (ESI-TOF/MS) analysis. To achieve this goal, first, the extraction process was evaluated by a comparative study using GRAS (Generally Recognized As Safe) solvents (mixtures of ethanol and water) at different temperatures (40–200 ◦C). The second step was to deeply characterize the composition of individual polyphenols by HPLC-ESI-TOF/MS in order to establish a comparison among the different PLE conditions applied to extract the phenolic fraction. The analysis revealed a wide variety of phenolic-composition, mainly phenolic acids and flavonoids. The results also highlighted that high percentages of ethanol and medium-high temperatures pointed out to be useful PLE conditions for recovering this kind of phytochemicals, which could be used in different applications, such as functional food ingredients, cosmetics, or nutraceuticals

    Dead-time optimization to increase secure distance range in prepare and measure quantum key distribution protocols

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    Afterpulsing is a factor limiting the distance over which discrete-variable quantum key distribution systems are secure, and a common feature in single-photon detectors. The relevance of this phenomenon stems from its stochastic, self-interacting nature and the fact that its rate rises with the number of avalanche events, which increases the quantum bit error rate. Here we introduce an effective analytic model, including dead-time and afterpulsing corrections, where afterpulsing correction depends on dead-time value. This model is useful to evaluate the performance of prepare and measure quantum key distribution protocols (standard and decoy versions) that use gated single photon detectors. The model provides an expression to numerically optimize the secret key rate over the full distance range for secure communication, enabling in this way the calculation of quantum bit error rate and secure key rate. In the conventional procedure, the dead-time value is fixed regardless of distance, limiting the distance range of the channel due to remaining afterpulsing effects, which are more relevant at higher operating frequencies. Here we demonstrate that optimizing the dead-time values increases the distance range of the channel to share secret keys.Comment: 13 pages, 9 figure

    Strain Relief Analysis of InN Quantum Dots Grown on GaN

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    We present a study by transmission electron microscopy (TEM) of the strain state of individual InN quantum dots (QDs) grown on GaN substrates. Moiré fringe and high resolution TEM analyses showed that the QDs are almost fully relaxed due to the generation of a 60° misfit dislocation network at the InN/GaN interface. By applying the Geometric Phase Algorithm to plan-view high-resolution micrographs, we show that this network consists of three essentially non-interacting sets of misfit dislocations lying along the directions. Close to the edge of the QD, the dislocations curve to meet the surface and form a network of threading dislocations surrounding the system

    Increased neurotransmitter release at the neuromuscular junction in a mouse model of polyglutamine disease

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    In Huntington’s disease (HD), the expansion of polyglutamine (polyQ) repeats at the N terminus of the ubiquitous protein huntingtin (htt) leads to neurodegeneration in specific brain areas. Neurons degenerating in HD develop synaptic dysfunctions. However, it is unknown whether mutant htt impacts synaptic function in general. To investigate that, we have focused on the nerve terminals of motor neurons that typically do not degenerate in HD. Here, we have studied synaptic transmission at the neuromuscular junction of transgenic mice expressing a mutant form of htt (R6/1 mice).Wehave found that the size and frequency of miniature endplate potentials are similar in R6/1 and control mice. In contrast, the amplitude of evoked endplate potentials in R6/1 mice is increased compared to controls. Consistent with a presynaptic increase of release probability, synaptic depression under high-frequency stimulation is higher in R6/1 mice. In addition, no changes were detected in the size and dynamics of the recycling synaptic vesicle pool. Moreover, we have found increased amounts of the synaptic vesicle proteins synaptobrevin 1,2/VAMP 1,2 and cysteine string protein-_, and the SNARE protein SNAP-25, concomitant with normal levels of other synaptic vesicle markers. Our results reveal that the transgenic expression of a mutant form of htt leads to an unexpected gain of synaptic function. That phenotype is likely not secondary to neurodegeneration and might be due to a primary deregulation in synaptic protein levels. Our findings could be relevant to understand synaptic toxic effects of proteins with abnormal polyQ repeats

    La convivencia escolar basada en la inteligencia emocional, desarrolla habilidades

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    This research establishes a school coexistence program, based on emotional intelligence, to develop soft skills in students of basic secondary education. Supported by a synchronous and asynchronous virtual tool, with parameters proposed by Goleman. Optimizing self-regulation skills, social skills and conflict resolution, to consolidate socially stable environments. Applied or practical research, with an experimental quantitative approach, from a quasiexperimental design, with two intact groups (experimental - control), a Likert scale instrument, subject to content validity and internal reliability. Population made up of 29898 students and an intentional sample, with similarity criteria of 534 students, from four educational institutions. The descriptive statistical analysis, show dynamics of significant changes, the behavior of its variables was estimated with the Shapiro-Willk test, with non-parametric distribution. The hypotheses were contrasted, using the Mann Whitney U test, with effective results: Self-control, Resilience, Leadership, Assertiveness, Teamwork, Empathy, Mediation, Conciliation, checking the alternative hypothesis, after the intervention, all the variables present differences and higher magnitudes, proving that there was significant progress. It is concluded that significant relationships were found between variables and dimensions,confirming that the teaching of soft skills has an impact on school coexistence.Keywords: School coexistence, emotional intelligence, soft skills.Esta investigación establece, un programa de convivencia escolar, basado en inteligencia emocional, para desarrollar las habilidades blandas, en estudiantes de educación básica secundaria. Apoyados en una herramienta virtual sincrónica y asincrónicamente, con parámetros propuestos por Goleman. Optimizando aptitudes de autorregulación, habilidades sociales y resolución de conflictos, para consolidar entornos socialmente estables. Investigación de tipo aplicada o práctica, con enfoque cuantitativo de tipo experimental, a partir de un diseño cuasi-experimental, con dos grupos intactos (experimental - control), un instrumento tipo escala de Likert, sometido a validez de contenido y confiabilidad interna. Población conformada por 29898 estudiantes y una muestra de tipo intencionada, con criterios de similitud de 534 estudiantes, de cuatros instituciones educativas. El análisis estadístico descriptivo, manifiestan dinámicas de cambios significativos, se estimó con test de Shapiro-Willk el comportamiento de sus variables, con distribución No Paramétrica. Se contrastó las hipótesis, mediante la prueba U. de Mann Whitney, con resultados efectivos: Autocontrol Resiliencia, Liderazgo Asertividad Trabajo en equipo Empatía, Mediación Conciliación, comprobando la hipótesis alterna, posterior a la intervención, todas las variables presentan diferencias y  magnitudes superiores, comprobando que hubo un progreso significativo. Se concluye que se encontraron relaciones significativas entre variables y dimensiones, confirmando que la enseñanza de las habilidades blandas, tiene incidencia en laconvivencia escolar.Palabras clave: Convivencia escolar, inteligencia emocional, habilidades blandas
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