СУЧАСНІ ВІТЧИЗНЯНІ ЗАСАДИ НАДАННЯ МЕДИЧНОЇ ДОПОМОГИ ДІТЯМ ПЕРШИХ РОКІВ ЖИТТЯ ІЗ ПОРУШЕННЯМ ЗОРОВИХ ФУНКЦІЙ

In the publication the scientific analysis of the researches of the organization of delivery of health care to children of the first years of life described in domestic and foreign literature with violation of visual functions, its staging, changes and innovations in connection with the increasing tendencies of quantity of cases of developing of a blindness and a decrease in visual functions is provided in early children's age, as in the world and in the countries of the European region, and in Ukraine, in particular.Features of the organization of rendering the treatment-and-prophylactic help to children with violations of visual functions at early age (from first years of life) as primary medical care in out-patient and polyclinic conditions, and in hospitals with rendering secondary medical and tertiary highly specialized medical care are analyzed. It is proved feasibility of complex intersectoral approach with involvement of parents in which families the child with violation of visual functions at early age, a medical personnel, specialists of education, visual impairment specialists in the solution of a complex medico-social problem of the organization of process of treatment, rehabilitation, education and development of children with violation of visual functions is brought up.В публикации приведен научный анализ описанных в отечественной и зарубежной литературе исследований организации оказания медицинской помощи детям первых лет жизни с нарушением зрительных функций. А также этапы, изменения и нововведения в связи с возрастающими тенденциями количества случаев возникновения слепоты и слабовидения в раннем детском возрасте как в мире и в странах Европейского региона, так и в Украине в частности. Проанализированы особенности организации оказания лечебно-профилактической помощи детям с нарушениями зрительных функций в раннем возрасте (с первых лет жизни) как первичной медицинской помощи в амбулаторно-поликлинических условиях, так и в стационарах с оказанием вторичной медицинской и третичной высокоспециализированной медицинской помощи. Обосновано целесообразность межсекторального подхода с вовлечением родителей, семьи в которой воспитывается ребенок с нарушением зрительных функций в раннем возрасте, медицинского персонала, специалистов образования, тифлопедагогов в решении сложной медико-социальной проблемы организации процесса лечения, реабилитации, воспитания и развития детей с нарушением зрительных функций.У публікації проведено науковий аналіз описаних у вітчизняній та зарубіжній літературі досліджень щодо організації надання медичної допомоги дітям перших років життя з порушенням зорових функційю.  А також етапи, зміни та нововведення у зв’язку із зростаючими тенденціями кількості випадків виникнення сліпоти й слабобачення в ранньому дитячому віці як у світі та у країнах Європейського регіону, так і в Україні зокрема. Проаналізовано особливості організації надання лікувально-профілактичної допомоги дітям із порушеннями зорових функцій у ранньому віці (з перших років життя) як первинної медичної допомоги в амбулаторно-поліклінічних умовах, так і в стаціонарах з наданням вторинної медичної та третинної високоспеціалізованої медичної допомоги. Обґрунтовано доцільність міжсекторального підходу із залученням батьків, родини, в якій виховується дитина з порушенням зорових функцій в ранньому віці, медичного персоналу, фахівців освіти, тифлопедагогів у вирішенні складної медико-соціальної проблеми організації процесу лікування, реабілітації, виховання та розвитку дітей із порушеннями зорових функцій

ЗНАЧЕННЯ ІНТРА- ТА ПІСЛЯОПЕРАЦІЙНИХ УСКЛАДНЕНЬ У ПРОГНОЗУВАННІ ВИХОДУ ХІРУРГІЧНОГО ЛІКУВАННЯ ПРОЛІФЕРАТИВНОЇ ДІАБЕТИЧНОЇ РЕТИНОПАТІЇ

The article describes  the results  in detection some factors that may predict visual outcome after vitrectomy for proliferative diabetic retinopathyВ статье представлены результаты определения прогностической ценности влияния факторов риска (интраоперационных и послеоперационных осложнений) на результат хирургического лечения пациентов с диабетической пролиферативной ретинопатией.У статті представлені результати визначення прогностичної цінності впливу інтраопераційних та післяопераційних ускладнень як факторів ризику на результат хірургічного втручання у хворих з проліферативною  діабетичною ретинопатією

Angiopoietins and prediction of vitreous hemorrhage in type 2 diabetes patients with diabetic retinopathy

Background: Various types of vitreoretinal surgery are used for the treatment of severe diabetic retinopathy (DR), with vitreous hemorrhage being a common postoperative complication. Impaired angiopoietin system function in type 2 diabetes mellitus (T2DM) patients with DR plays a role in retinal vascular damage and may determine the development of vitreous hemorrhage, e.g., after vitrectomy. Purpose: To identify the effects of angiopoietins on and their prognostic value in the development of vitreous hemorrhage after advanced vitreoretinal surgery in T2DM patients with DR. Material and Methods: The study included 118 T2DM patients (118 eyes) with DR. These included patients with mild nonproliferative DR (NPDR; Group 1; n = 28), moderate or severe NPDR (Group 2; n = 49), and proliferative DR (PDR; Group 3; n = 41). They underwent a 25-G closed subtotal vitrectomy (CSTV) with panretinal laser photocoagulation. Either a mixture of perfluoropropane (18% C3F8) and air was used to perform tamponade of the vitreous cavity or balance salt solution (BSS plus) was left in the vitreous cavity. Vitreous samples were obtained during vitrectomy, and Ang1 and Ang2 concentrations and their ratio for these samples were measured by enzyme-linked immunosorbent assay. Models were developed using the EZR version 1.54 software (Saitama Medical Center, Jichi Medical University, Saitama, Japan), which is a graphical user interface for R (The R Foundation for Statistical Computing; Vienna, Austria). Results: Vitreous hemorrhage developed in 33.1% of patients with T2DM by three months after vitrectomy for DR, and was directly associated with increased levels of Ang1 and Ang2 in the vitreous (p < 0.005). After adjustment for DR severity stage, the risk of postoperative vitreous hemorrhage in patients with mild NPDR was associated with an increased level of Ang2 in the vitreous (OR, 1.95; 95% CI, 1.06-3.59 per 100 pg/ml), with an optimal cut-off point of 1246 pg/ml (р = 0.003). The risk of postoperative vitreous hemorrhage in patients with severe NPDR and PDR was associated with the level of Ang2 as well as the Ang2/ Ang1 ratio in the vitreous. The study identified cut-off vitreous levels of Ang2 of (a) 2806 pg/mL for moderate or severe NPDR (AUC=0.84; 95% CI, 0.71-0.93; p < 0.001) and (b) 4610 pg/mL for PDR (AUC=0.71; 95% CI, 0.55-0.84; p = 0.013). Conclusion: The results obtained demonstrated that Ang2 accumulation in the vitreous resulted in an increased risk of postoperative vitreous hemorrhage, and was of high prognostic significance

Anomalously large oxygen-ordering contribution to the thermal expansion of untwinned YBa2Cu3O6.95 single crystals: a glass-like transition near room temperature

We present high-resolution capacitance dilatometry studies from 5 - 500 K of untwinned YBa2Cu3Ox (Y123) single crystals for x ~ 6.95 and x = 7.0. Large contributions to the thermal expansivities due to O-ordering are found for x ~ 6.95, which disappear below a kinetic glass-like transition near room temperature. The kinetics at this glass transition is governed by an energy barrier of 0.98 +- 0.07 eV, in very good agreement with other O-ordering studies. Using thermodynamic arguments, we show that O-ordering in the Y123 system is particularly sensitive to uniaxial pressure (stress) along the chain axis and that the lack of well-ordered chains in Nd123 and La123 is most likely a consequence of a chemical-pressure effect.Comment: 4 pages, 3 figures, submitted to PR

Superconducting Gap and Strong In-Plane Anisotropy in Untwinned YBa2Cu3O7-d

With significantly improved sample quality and instrumental resolution, we clearly identify in the (pi,0) ARPES spectra from YBa2Cu3O6.993, in the superconducting state, the long-sought `peak-dip-hump' structure. This advance allows us to investigate the large a-b anisotropy of the in-plane electronic structure including, in particular, a 50% difference in the magnitude of the superconducting gap that scales with the energy position of the hump feature. This anisotropy, likely induced by the presence of the CuO chains, raises serious questions about attempts to quantitatively explain the YBa2Cu3O7-d data from various experiments using models based on a perfectly square lattice.Comment: Phys. Rev. Lett., in press. Revtex, 4 pages, 4 postscript figures embedded in the tex

Angle-resolved photoemission study of untwinned PrBa2_2Cu3_3O7_7: undoped CuO2_2 plane and doped CuO3_3 chain

We have performed an angle-resolved photoemission study on untwinned PrBa$_2$Cu$_3$O$_7$, which has low resistivity but does not show superconductivity. We have observed a dispersive feature with a band maximum around ($\pi$/2,$\pi$/2), indicating that this band is derived from the undoped CuO$_2$ plane. We have observed another dispersive band exhibiting one-dimensional character, which we attribute to signals from the doped CuO$_3$ chain. The overall band dispersion of the one-dimensional band agrees with the prediction of $t-J$ model calculation with parameters relevant to cuprates except that the intensity near the Fermi level is considerably suppressed in the experiment.Comment: 6 pages, 10 figure

Commensurate dynamic magnetic correlations in La2(Cu,Li)O4

When sufficient numbers of holes are introduced into the two-dimensional CuO2 square lattice, dynamic magnetic correlations become incommensurate with underlying lattice in all previously investigated La_{2-x}A_xCu_{1-z}B_zO_{4+y} (A=Sr or Nd, B=Zn) including high T_C superconductors and insulators, and in bilayered superconducting YBa_2Cu_3O_{6.6} and Bi_2Sr_2CaCu_2O_8. Magnetic correlations also become incommensurate in structurally related La_2NiO_4 when doped with Sr or O. We report an exception to this so-far well established experimental "rule" in La_2Cu_{1-z}Li_{z}O_4 in which magnetic correlations remain commensurate.Comment: 4 pages, 3 figures, revised version as for publicatio

Azimuthal anisotropy and correlations in the hard scattering regime at RHIC

Azimuthal anisotropy ($v_2$) and two-particle angular correlations of high $p_T$ charged hadrons have been measured in Au+Au collisions at $\sqrt{s_{NN}}$=130 GeV for transverse momenta up to 6 GeV/c, where hard processes are expected to contribute significantly. The two-particle angular correlations exhibit elliptic flow and a structure suggestive of fragmentation of high $p_T$ partons. The monotonic rise of $v_2(p_T)$ for $p_T<2$ GeV/c is consistent with collective hydrodynamical flow calculations. At \pT>3 GeV/c a saturation of $v_2$ is observed which persists up to $p_T=6$ GeV/c.Comment: As publishe

High-pT pi^zero Production with Respect to the Reaction Plane in Au + Au Collisions at sqrt(s_NN) = 200 GeV

Measurements of the azimuthal anisotropy of high-\pT neutral pion neutral pion production in Au+Au collisions at sqrt(s_NN) = 200 GeV by the PHENIX experiment are presented. The data included in this paper were collected during the 2004 RHIC running period and represent approximately an order of magnitude increase in the number of analyzed events relative to previously published results. Azimuthal angle distributions of pi^0s detected in the PHENIX electromagnetic calorimeters are measured relative to the reaction plane determined event-by-event using the forward and backward beam-beam counters. Amplitudes of the second Fourier component (v_2) of the angular distributions are presented as a function of pi^0 transverse momentum p_T for different bins in collision centrality. Measured reaction plane dependent pi^0 yields are used to determine the azimuthal dependence of the pi^0 suppression as a function of p_T, R_AA (Delta phi,p_T). A jet-quenching motivated geometric analysis is presented that attempts to simultaneously describe the centrality dependence and reaction plane angle dependence of the pi^0 suppression in terms of the path lengths of hypothetical parent partons in the medium. This set of results allows for a detailed examination of the influence of geometry in the collision region, and of the interplay between collective flow and jet-quenching effects along the azimuthal axis.Comment: 344 authors, 35 pages text, RevTeX-4, 24 figures, 8 tables. Submitted to Physical Review

Azimuthal anisotropy of K0S and Lambda + Lambda -bar production at midrapidity from Au+Au collisions at sqrt[sNN]=130 GeV

We report STAR results on the azimuthal anisotropy parameter v2 for strange particles K0S, Lambda , and Lambda -bar at midrapidity in Au+Au collisions at sqrt[sNN]=130 GeV at the Relativistic Heavy Ion Collider. The value of v2 as a function of transverse momentum, pt, of the produced particle and collision centrality is presented for both particles up to pt~3.0 GeV/c. A strong pt dependence in v2 is observed up to 2.0 GeV/c. The v2 measurement is compared with hydrodynamic model calculations. The physics implications of the pt integrated v2 magnitude as a function of particle mass are also discussed.Alle Autoren: C. Adler, Z. Ahammed, C. Allgower, J. Amonett, B. D. Anderson, M. Anderson, G. S. Averichev, J. Balewski, O. Barannikova, L. S. Barnby, J. Baudot, S. Bekele, V. V. Belaga, R. Bellwied, J. Berger, H. Bichsel, A. Billmeier, L. C. Bland, C. O. Blyth, B. E. Bonner, A. Boucham, A. Brandin, A. Bravar, R. V. Cadman, H. Caines, M. Calderón de la Barca Sánchez, A. Cardenas, J. Carroll, J. Castillo, M. Castro, D. Cebra, P. Chaloupka, S. Chattopadhyay, Y. Chen, S. P. Chernenko, M. Cherney, A. Chikanian, B. Choi, W. Christie, J. P. Coffin, T. M. Cormier, J. G. Cramer, H. J. Crawford, W. S. Deng, A. A. Derevschikov, L. Didenko, T. Dietel, J. E. Draper, V. B. Dunin, J. C. Dunlop, V. Eckardt, L. G. Efimov, V. Emelianov, J. Engelage, G. Eppley, B. Erazmus, P. Fachini, V. Faine, K. Filimonov, E. Finch, Y. Fisyak, D. Flierl, K. J. Foley, J. Fu, C. A. Gagliardi, N. Gagunashvili, J. Gans, L. Gaudichet, M. Germain, F. Geurts, V. Ghazikhanian, O. Grachov, V. Grigoriev, M. Guedon, E. Gushin, T. J. Hallman, D. Hardtke, J. W. Harris, T. W. Henry, S. Heppelmann, T. Herston, B. Hippolyte, A. Hirsch, E. Hjort, G. W. Hoffmann, M. Horsley, H. Z. Huang, T. J. Humanic, G. Igo, A. Ishihara, Yu. I. Ivanshin, P. Jacobs, W. W. Jacobs, M. Janik, I. Johnson, P. G. Jones, E. G. Judd, M. Kaneta, M. Kaplan, D. Keane, J. Kiryluk, A. Kisiel, J. Klay, S. R. Klein, A. Klyachko, A. S. Konstantinov, M. Kopytine, L. Kotchenda, A. D. Kovalenko, M. Kramer, P. Kravtsov, K. Krueger, C. Kuhn, A. I. Kulikov, G. J. Kunde, C. L. Kunz, R. Kh. Kutuev, A. A. Kuznetsov, L. Lakehal-Ayat, M. A. C. Lamont, J. M. Landgraf, S. Lange, C. P. Lansdell, B. Lasiuk, F. Laue, A. Lebedev, R. Lednický, V. M. Leontiev, M. J. LeVine, Q. Li, S. J. Lindenbaum, M. A. Lisa, F. Liu, L. Liu, Z. Liu, Q. J. Liu, T. Ljubicic, W. J. Llope, G. LoCurto, H. Long, R. S. Longacre, M. Lopez-Noriega, W. A. Love, T. Ludlam, D. Lynn, J. Ma, R. Majka, S. Margetis, C. Markert, L. Martin, J. Marx, H. S. Matis, Yu. A. Matulenko, T. S. McShane, F. Meissner, Yu. Melnick, A. Meschanin, M. Messer, M. L. Miller, Z. Milosevich, N. G. Minaev, J. Mitchell, V. A. Moiseenko, C. F. Moore, V. Morozov, M. M. de Moura, M. G. Munhoz, J. M. Nelson, P. Nevski, V. A. Nikitin, L. V. Nogach, B. Norman, S. B. Nurushev, G. Odyniec, A. Ogawa, V. Okorokov, M. Oldenburg, D. Olson, G. Paic, S. U. Pandey, Y. Panebratsev, S. Y. Panitkin, A. I. Pavlinov, T. Pawlak, V. Perevoztchikov, W. Peryt, V. A Petrov, M. Planinic, J. Pluta, N. Porile, J. Porter, A. M. Poskanzer, E. Potrebenikova, D. Prindle, C. Pruneau, J. Putschke, G. Rai, G. Rakness, O. Ravel, R. L. Ray, S. V. Razin, D. Reichhold, J. G. Reid, F. Retiere, A. Ridiger, H. G. Ritter, J. B. Roberts, O. V. Rogachevski, J. L. Romero, A. Rose, C. Roy, V. Rykov, I. Sakrejda, S. Salur, J. Sandweiss, A. C. Saulys, I. Savin, J. Schambach, R. P. Scharenberg, N. Schmitz, L. S. Schroeder, A. Schüttauf, K. Schweda, J. Seger, D. Seliverstov, P. Seyboth, E. Shahaliev, K. E. Shestermanov, S. S. Shimanskii, V. S. Shvetcov, G. Skoro, N. Smirnov, R. Snellings, P. Sorensen, J. Sowinski, H. M. Spinka, B. Srivastava, E. J. Stephenson, R. Stock, A. Stolpovsky, M. Strikhanov, B. Stringfellow, C. Struck, A. A. P. Suaide, E. Sugarbaker, C. Suire, M. Šumbera, B. Surrow, T. J. M. Symons, A. Szanto de Toledo, P. Szarwas, A. Tai, J. Takahashi, A. H. Tang, J. H. Thomas, M. Thompson, V. Tikhomirov, M. Tokarev, M. B. Tonjes, T. A. Trainor, S. Trentalange, R. E. Tribble, V. Trofimov, O. Tsai, T. Ullrich, D. G. Underwood, G. Van Buren, A. M. VanderMolen, I. M. Vasilevski, A. N. Vasiliev, S. E. Vigdor, S. A. Voloshin, F. Wang, H. Ward, J. W. Watson, R. Wells, G. D. Westfall, C. Whitten, Jr., H. Wieman, R. Willson, S. W. Wissink, R. Witt, J. Wood, N. Xu, Z. Xu, A. E. Yakutin, E. Yamamoto, J. Yang, P. Yepes, V. I. Yurevich, Y. V. Zanevski, I. Zborovský, H. Zhang, W. M. Zhang, R. Zoulkarneev, and A. N. Zubarev (STAR Collaboration