6 research outputs found
Patterns of HIV prevalence among injecting drug users in the cross-border area of Lang Son Province, Vietnam, and Ning Ming County, Guangxi Province, China
- Author
- C Beyrer
- DC Des Jarlais
- Doan Ngu
- Don C Des Jarlais
- G Stimson
- GV Stimson
- GV Stimson
- J Holland
- JH Elliott
- JP Grund
- Kieu T Binh
- KJP Craib
- Ly K Van
- Meng Donghua
- NAIDSC Organization
- Nguyen D Tung
- Patricia Friedmann
- Patrick Johnston
- RT D'Aquila
- Ryan Kling
- SH Weiss
- Theodore M Hammett
- TM Hammet
- TM Hammett
- Tran V Hoang
- TV Hoang
- Wei Liu
- Yi Chen
- Publication venue
- BioMed Central
- Publication date
- 24/08/2005
- Field of study
BACKGROUND: To assess patterns of injecting drug use and HIV prevalence among injecting drug users (IDUs) in an international border area along a major heroin trans-shipment route. METHODS: Cross-sectional surveys of IDUs in 5 sites in Lang Son Province, Vietnam (n = 348) and 3 sites in Ning Ming County, Guangxi Province, China (n = 308). Respondents were recruited through peer referral ("snowball") methods in both countries, and also from officially recorded lists of IDUs in Vietnam. A risk behavior questionnaire was administered and HIV counseling and testing conducted. RESULTS: Participants in both countries were largely male, in their 20s, and unmarried. A majority of subjects in both countries were members of ethnic minority groups. There were strong geographic gradients for length of drug injecting and for HIV seroprevalence. Both mean years injecting and HIV seroprevalence declined from the Vietnamese site farthest from the border to the Chinese site farthest from the border. 10.6% of participants in China and 24.5% of participants in Vietnam reported crossing the international border in the 6 months prior to interview. Crossing the border by IDUs was associated with (1) distance from the border, (2) being a member of an ethnic minority group, and (3) being HIV seropositive among Chinese participants. CONCLUSION: Reducing the international spread of HIV among IDUs will require programs at the global, regional, national, and "local cross border" levels. At the local cross border level, the programs should be coordinated on both sides of the border and on a sufficient scale that IDUs will be able to readily obtain clean injection equipment on the other side of the border as well as in their country of residence
Exposure of neonatal rats to maternal cafeteria feeding during suckling alters hepatic gene expression and DNA methylation in the insulin signalling pathway
- Author
- A Akyol
- A Akyol
- A Foryst-Ludwig
- A Kahn
- A Swali
- A Swali
- AK Kant
- AM Samuelsson
- Asli Akyol
- B Schwanhäusser
- BP Sampey
- BR Carone
- C Torrens
- C Vogel
- DS Fernandez-Twinn
- GC Burdge
- I Bogdarina
- J Carlin
- K Kadowaki
- K Shankar
- KA Lillycrop
- KA Lillycrop
- KD Sinclair
- KJP Ryan
- L Gambling
- M Szyf
- M Viana Abranches
- MH Vickers
- MP Menendez-Gutierrez
- NJ Rothwell
- OH Lowry
- R Buettner
- RM Austin
- S McMullen
- SA Bayol
- SA Bayol
- SA Langie
- Sarah McMullen
- SC Jacobsen
- SC Langley
- SC Langley-Evans
- Simon C. Langley-Evans
- SR Crozier
- SZ Duan
- T Masaki
- Y Seki
- Z Yates
- Z Zhou
- ZE Floyd
- Zoe C. Daniel
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 20/12/2013
- Field of study
Nutrition in early life is a determinant of lifelong physiological and metabolic function. Diseases that are associated with ageing may, therefore, have their antecedents in maternal nutrition during pregnancy and lactation. Rat mothers were fed either a standard laboratory chow diet (C) or a cafeteria diet (O) based upon a varied panel of highly palatable human foods, during lactation. Their offspring were then weaned onto chow or cafeteria diet giving four groups of animals (CC, CO, OC, OO n=9-10). Livers were harvested 10 weeks post-weaning for assessment of gene and protein expression, and DNA methylation. Cafeteria feeding post-weaning impaired glucose tolerance and was associated with sex-specific altered mRNA expression of peroxisome proliferator activated receptor gamma (PPARg) and components of the insulin-signalling pathway (Irs2, Akt1 and IrB). Exposure to the cafeteria diet during the suckling period modified the later response to the dietary challenge. Post-weaning cafeteria feeding only down-regulated IrB when associated with cafeteria feeding during suckling (group OO, interaction of diet in weaning and lactation P=0.041). Responses to cafeteria diet during both phases of the experiment varied between males and females. Global DNA methylation was altered in the liver following cafeteria feeding in the post-weaning period, in males but not females. Methylation of the IrB promoter was increased in group OC, but not OO (P=0.036). The findings of this study add to a growing evidence base that suggests tissue function across the lifespan a product of cumulative modifications to the epigenome and transcriptome, which may be both tissue and sex-specific
Dose-dependent effects of Vitamin D on transdifferentiation of skeletal muscle cells to adipose cells
- Publication venue
- 'Society for Endocrinology'
- Publication date
- Field of study
A familial tendency for developing inguinal hernias: study of a single family
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Housing Instability among People Who Inject Drugs: Results from the Australian Needle and Syringe Program Survey
- Author
- A Palepu
- B White
- BB Benda
- BDL Marshall
- BE Molnar
- C Chamberlain
- C Grigsby
- C Kim
- C Zlotnick
- CA Latkin
- CL Miller
- Commonwealth of Australia
- D Padgett
- DB Herman
- DB Herman
- DE McNiel
- DM Patrick
- E Baldry
- E Baldry
- E Wood
- Eileen Baldry
- G Johnson
- GA Greenberg
- H Klee
- H Klee
- HA Siegal
- HG Prigerson
- J Fountain
- J Iversen
- J Minnery
- J Mitchell
- J Neale
- J Spauwen
- J Ward
- JB Vangeest
- JC Reyes
- JD Wright
- Jenny Iversen
- JF Andia
- JM Greene
- JY Song
- KD Ryan
- KH Shelton
- KJP Craib
- L Topp
- L Topp
- Libby Topp
- Lisa Maher
- M Hickman
- M MacDonald
- M Reardon
- M Teesson
- M Teesson
- MA MacDonald
- MH Coady
- MJ Robertson
- N Craine
- NC Babidge
- NG Shah
- NM Wright
- P Koegel
- P Reid
- PA Kemp
- PE Bebbington
- PM Spittal
- RG Smart
- RW Parks
- S Allgood
- S Amesty
- S Darke
- S Darke
- S Fazel
- S Green
- S Metraux
- SA Strathdee
- SM Barrow
- SW Hwang
- T Rhodes
- T Rhodes
- TA Corneil
- TP Johnson
- TP Johnson
- TP O’Toole
- W Martens
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A second update on mapping the human genetic architecture of COVID-19
- Author
- Abd Elghafar MS
- Abdel-Aziz M
- Abdelrazik M
- Abdullah MS
- Abe R
- Abe S
- Abel L
- Abel L
- Abernathy C
- Abraham R
- Abraheem A
- Abu Alragheb BO
- Abulail JA
- Acklery A
- Acosta-Herrera M
- Adachi T
- Adachi Y
- Adam R
- Adams C
- Adams K
- Adams N
- Adanini O
- Afifi N
- Afilalo J
- Afilalo M
- Afolabi D
- Afrasiabi Z
- Afset JE
- Agasou A
- Aghemo A
- Agravante K
- Agrawal A
- Agrawal S
- Aguado JM
- Aguilar C
- Aguilar SEV
- Aguilar-Salinas CA
- Aguilera-Albesa S
- Agüero D
- Ahmad HF
- Ahmad N
- Ahmadhaider N
- Ahmed A
- Ahmed C
- Ahram M
- Ai M
- Ain Q
- Aitkin E
- Akeroyd L
- Akhtar MN
- Akinkugbe O
- Al-Ani A
- Al-Ja’afreh MM
- Al-Kadash A
- Al-Kasasbeh MM
- Al-Moasseb H
- Al-Muftah W
- Al-Sarraj Y
- Alamer LM
- Alasdair F
- Alawneh FM
- Alawneh LM
- Albaiceta GM
- Albano G
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- Ward K
- Ward L
- Ward M
- Ward S
- Warden S
- Warren D
- Warrington J
- Washington NL
- Wassall H
- Wasson C
- Watanabe H
- Watanabe K
- Waters A
- Waters E
- Watkins C
- Watson E
- Watson G
- Watson J
- Watters M
- Watts S
- Waugh V
- Weaver J
- Webb N
- Webster A
- Webster D
- Webster K
- Wei S
- Wei Z
- Weiss ST
- Weldon CH
- Welford A
- Wells C
- Welters I
- Wendorff M
- Wendtner CM
- Werge T
- Wesse T
- West J
- Westergaard D
- Weston H
- Whileman A
- Whitaker E
- Whitbread J
- White D
- White I
- White K
- White M
- White N
- White N
- White S
- Whitehead V
- Whitelaw L
- Whiteley S
- Whiteside J
- Whitney J
- Whitton C
- Whyte C
- Wicks SJ
- Wiegrebe S
- Wienbrandt L
- Wignall A
- Wilby L
- Wilcox L
- Wild H
- Wild L
- Wilding L
- Wiles M
- Wilfling S
- Wiliams A
- Wilkin F
- Wilkins J
- Wilkinson A
- Wilkinson B
- Williams A
- Williams A
- Williams C
- Williams D
- Williams E
- Williams E
- Williams G
- Williams H
- Williams J
- Williams K
- Williams M
- Williams P
- Williams S
- Williams T
- Willis C
- Willis H
- Wills M
- Willson J
- Wilson A
- Wilson DJ
- Wilson J
- Wilson JF
- Wiltfang J
- Winchester J
- Winkler TW
- Winmill H
- Winnard S
- Winter C
- Winter K
- Winter-Goodwin B
- Wittig M
- Witzke O
- Wolf-Roberts R
- Wolford BN
- Wong I
- Wong J
- Wong J
- Wood D
- Wood H
- Wood S
- Wood S
- Wood T
- Woodford C
- Woodruff M
- Woods L
- Woodward E
- Woodward J
- Woolcock M
- Woolley AE
- Worner R
- Worsley L
- Wray G
- Wren L
- Wreybrown C
- Wright C
- Wright DJ
- Wright J
- Wright M
- Wright S
- Wrobel N
- Wu Y
- Wulandari R
- Wylie K
- Wyllie DH
- Wynter I
- Xavier K
- Xue X
- Yagi K
- Yamada M
- Yamada Y
- Yamagata K
- Yamasaki M
- Yang J
- Yaspan B
- Yassen AM
- Yasui Y
- Yates B
- Yatomi M
- Ye C
- Yermakovich D
- Yeung RSM
- Yi X
- Yonekawa A
- Yoo S
- Yoon K
- Yoshida K
- Yoshida S
- Yoshida S
- Yoshida T
- Yoshihara T
- Yoshiya K
- Yoshiyama T
- Young M
- Yue F
- Yun N
- Yáñez CE
- Yáñez Z
- Zainulabid UA
- Zainy T
- Zak A
- Zaki A
- Zamikula J
- Zamudio IPM
- Zanella A
- Zapata-Contreras D
- Zapatamartinez M
- Zarate R
- Zarei N
- Zavaleta DAF
- Zawadzki P
- Zawati MH
- Zborowski AC
- Zeberg H
- Zechner M
- Zhang Q
- Zhao X
- Zheng C
- Zheng T
- Zhlawi HJ
- Zhlawi MWJ
- Zholdybayeva E
- Zhou W
- Zhu W
- Zitter L
- Zoller H
- Zongo O
- Zorloni C
- Zuñiga-Pacheco P
- Zárate RN
- Zúñiga-Ramos J
- Álvarez BG
- Ávila-Arcos MA
- Ávila-Arcos MC
- Özer O
- Überla K
- Þorsteinsdóttir U
- Publication venue
- Nature Research
- Publication date
- 21/06/2023
- Field of study