Contribuţiile asistenţei morfopatologice în evaluarea letalităţii la copii

Prezentul articol refl ectă evaluarea letalităţii în perioadele de dezvoltare a copilului pe parcursul anilor 2006-2008 în cadrul Asistenţei Morfopatologice în Secţia Anatomie Patologică Centralizată (SAPC) a IMSP ICŞDOSMşiC în baza analizei retrospective a 787 de procese-verbale ale investigaţiilor morfopatologice. Rezultatele obţinute au refl ectat structura, patologiile predominante şi dinamismul acestora, precum şi ponderea divergenţelor de diagnostic

H0LiCOW III. Quantifying the effect of mass along the line of sight to the gravitational lens HE 0435-1223 through weighted galaxy counts

Based on spectroscopy and multiband wide-field observations of the gravitationally lensed quasar HE 0435-1223, we determine the probability distribution function of the external convergence $\kappa_\mathrm{ext}$ for this system. We measure the under/overdensity of the line of sight towards the lens system and compare it to the average line of sight throughout the universe, determined by using the CFHTLenS as a control field. Aiming to constrain $\kappa_\mathrm{ext}$ as tightly as possible, we determine under/overdensities using various combinations of relevant informative weighing schemes for the galaxy counts, such as projected distance to the lens, redshift, and stellar mass. We then convert the measured under/overdensities into a $\kappa_\mathrm{ext}$ distribution, using ray-tracing through the Millennium Simulation. We explore several limiting magnitudes and apertures, and account for systematic and statistical uncertainties relevant to the quality of the observational data, which we further test through simulations. Our most robust estimate of $\kappa_\mathrm{ext}$ has a median value $\kappa^\mathrm{med}_\mathrm{ext} = 0.004$ and a standard deviation of $\sigma_\kappa = 0.025$. The measured $\sigma_\kappa$ corresponds to $2.5\%$ uncertainty on the time delay distance, and hence the Hubble constant $H_0$ inference from this system. The median $\kappa^\mathrm{med}_\mathrm{ext}$ value is robust to $\sim0.005$ (i.e. $\sim0.5\%$ on $H_0$) regardless of the adopted aperture radius, limiting magnitude and weighting scheme, as long as the latter incorporates galaxy number counts, the projected distance to the main lens, and a prior on the external shear obtained from mass modeling. The availability of a well-constrained $\kappa_\mathrm{ext}$ makes \hequad\ a valuable system for measuring cosmological parameters using strong gravitational lens time delays.Comment: 24 pages, 17 figures, 6 tables. Submitted to MNRA

Melanoma’s sentinel node biopsy: comparison between two clinical hospitals over 5 years

University of Medicine and Pharmacy of Targu Mures, Romania, University Hospital of Parma, ItalyIntroduction. Sentinel lymph node (SLN) is defined as the first lymph node localized on the direct lymphatic drainage pathway from a primary tumor. The sentinel lymph node biopsy (SLNB) is largely used in breast cancer and melanoma but it may also be useful in other epithelial skin cancers as well as in tumors located in the upper or lower gastrointestinal tract, lungs, thyroid, cervix and vulva. SLNB in melanoma is essential for an accurate staging, to estimate the risk of extension to other lymph nodes or organs and to evaluate the prognosis. Melanoma, even if it is not as common as the basal cell carcinoma or squamous cell carcinoma among the skin tumors, presents an increasing incidence and a higher mortality

Nematodele parazite la cartofii de diferite soiuri și interrelațiile cu unele artropode

Institute of Zoology, MECR, Chisinau, Republic of Moldova, Institute of Genetics Physiology and Plants Protection, MECR, Chisinau, Republic of MoldovaIntroduction. Potato (Solanum tuberosum L.) is susceptible to infestation with an associated complex of different species of parasitic and saprophytic nematodes, bacteria, fungi, and arthropods, which diminish the quality of the product. Material and methods. 10 varieties of potatoes were investigated (Agata, Albastriu-mov, Bella rosa, Concorde, Desiree, Irga, Iagodca, Roko, Romano, Sprinter), cultivated on the territory of the Republic of Moldova. The extraction of nematodes and mites was performed using the Baermann funnels, modified by Nesterov. Results. Multiannual researches on the degree of potato infestation have shown that tubers are preferred by various arthropods (Acaridae), Agriothes spp. (Elateridae), Gryllotalpa gryllotalpa, (Grillotalpidae) and Sciaridae spp. (Sciaridae), which form different interactions with the parasitic nematodes of tubers (Ditylenchus destructor, D. dipsaci). Conclusions. Solanum tuberosum infested by parasitic nematodes D. destructor in association with saprophytic nematodes and dry rot are colonized by nematophagous (mites – 80%) and phytophagous arthropods (wireworms – 40%; mole cricket – 50%; flies – 40%). Among the researched arthropods, Rhizoglyphus echinopus were more frequently found, which together with other species actively consume the primary and secondary parasitic nematodes, their mortality constituting up to 90%. In the traumatized by some arthropods potatoes, with the soil, secondary parasitic nematodes, also penetrate, carrying bacterial and fungal infections, subsequently stimulating the total rot of potato tubers.Introducere. Cartoful (Solanum tuberosum L) este susceptibil la infestare cu un complex asociat de diferite specii de nematode parazite, saprofite, bacterii, ciuperci și artropode, ceea ce îi diminuează din calitatea lui ca produs. Material și metode. Au fost cercetate 10 soiuri de cartofi (Agata, Albăstriu-mov, Bella rosa, Concorde, Desiree, Irga, Iagodka, Rocko, Romano, Sprinter) cultivate în Republica Moldova. Extragerea nematodelor și a acarienilor s-a efectuat cu utilizarea pâlniilor Baermann, modificate de Nesterov. Rezultate. Cercetările multianuale, privind gradul de infestare a cartofilor, au demonstrat că tuberculii sunt preferați de diferite artropode: Agriotes spp. (Elateridae), Gryllotalpa gryllotalpa, (Grillotalpidae) și Sciaridae spp. (Sciaridae), care stabilesc interrelații diverse cu nematodele parazite (Ditylenchus destructor, D. dipsaci) ale culturii. Concluzii. Solanum tuberosum, infestat de nematodul parazit Ditylenchus destructor, în asociere cu nematodele saprofite și cu putregaiul uscat, este colonizat de artropodele nematofage (acarieni – 80%) și fitofage (viermii-sârmă – 40%; coropișnițe – 50%; musculițe – 40%). Printre artropodele cercetate, mai frecvent a fost atestat Rhizoglyphus echinopus(Fumouze & Robin, 1868), care, împreună cu alte specii, consumă activ nematodele parazite primare și pe cele secundare, mortalitatea acestora constituind până la 90%. În cartofii traumați de unele artropode, odată cu solul, pătrund și nematodele parazite secundare, purtătoare ale infecțiilor bacteriene și fungice, stimulând ulterior putrefacția totală a tuberculilor

Parasitic nematodes in potatoes of different varieties and their interrelations with some arthropods

Introduction. Potato (Solanum tuberosum L.) is susceptible to infestation with an associated complex of different species of parasitic and saprophytic nematodes, bacteria, fungi, and arthropods, which diminish the quality of the product. Material and methods. 10 varieties of potatoes were investigated (Agata, Albastriu-mov, Bella rosa, Concorde, Desiree, Irga, Iagodca, Roko, Romano, Sprinter), cultivated on the territory of the Republic of Moldova. The extraction of nematodes and mites was performed using the Baermann funnels, modified by Nesterov. Results. Multiannual researches on the degree of potato infestation have shown that tubers are preferred by various arthropods (Acaridae), Agriothes spp. (Elateridae), Gryllotalpa gryllotalpa, (Grillotalpidae) and Sciaridae spp . (Sciaridae), which form different interactions with the parasitic nematodes of tubers (Ditylenchus destructor, D. dipsaci). Conclusions. Solanum tuberosum infested by parasitic nematodes D. destructor in association with saprophytic nematodes and dry rot are colonized by nematophag ous (mites – 80%) and phytophagous arthropods (wireworms – 40%; mole cricket – 50%; flies – 40%). Among the researched arthropods, Rhizoglyphus echinopus were more frequently found, which together with other species actively consume the primary and secondary parasitic nematodes, their mortality constituting up to 90%. In the traumatized by some arthropods potatoes, with the soil, secondary parasitic nematodes, also penetrate, carrying bacterial and fungal infections, subsequently stimulating the total rot of potato tubers

H0LiCOW XII. Lens mass model of WFI2033-4723 and blind measurement of its time-delay distance and H0H_0

We present the lens mass model of the quadruply-imaged gravitationally lensed quasar WFI2033-4723, and perform a blind cosmographical analysis based on this system. Our analysis combines (1) time-delay measurements from 14 years of data obtained by the COSmological MOnitoring of GRAvItational Lenses (COSMOGRAIL) collaboration, (2) high-resolution $\textit{Hubble Space Telescope}$ imaging, (3) a measurement of the velocity dispersion of the lens galaxy based on ESO-MUSE data, and (4) multi-band, wide-field imaging and spectroscopy characterizing the lens environment. We account for all known sources of systematics, including the influence of nearby perturbers and complex line-of-sight structure, as well as the parametrization of the light and mass profiles of the lensing galaxy. After unblinding, we determine the effective time-delay distance to be $4784_{-248}^{+399}~\mathrm{Mpc}$, an average precision of $6.6\%$. This translates to a Hubble constant $H_{0} = 71.6_{-4.9}^{+3.8}~\mathrm{km~s^{-1}~Mpc^{-1}}$, assuming a flat $\Lambda$CDM cosmology with a uniform prior on $\Omega_\mathrm{m}$ in the range [0.05, 0.5]. This work is part of the $H_0$ Lenses in COSMOGRAIL's Wellspring (H0LiCOW) collaboration, and the full time-delay cosmography results from a total of six strongly lensed systems are presented in a companion paper (H0LiCOW XIII).Comment: Version accepted by MNRAS. 29 pages including appendix, 17 figures, 6 tables. arXiv admin note: text overlap with arXiv:1607.0140

Epidemiology of echinococcosis and changes in some chimical indicies of muscular tissue and liver of cattle in the Republic of Moldova

The study of the parasitological invasions with Echinococcus granulosus in about 8000 cattle have been carried out in different time periods (1986-1987, 2014-2015) in private farms, family household and specialized in milk and beef production farming sectors from the Republic of Moldova. The results of the parasitological research carried out in 1986-1987 have revealed the 33.6% incidence of echinococcosis in adult cattle from farming sectors, 60.6% incidence in farms and 76.5% in cattle from family household (mean 56.9%); the incidence related to bull-calves population (of 23-25 months old) were 8.3%, 17.7% and 21.1% correspondingly (mean 15.7%). In the period 2014-2015, after the restructuring carried out in the livestock, the results show that adult cattle from farms were infested at 74.6%, in individual sector - in 83.7% of cases (mean 79.2%) and young cattle (23-25 months old) - in 31.2% and 37.4% cases correspondingly (mean 34.3%). Compared to 1986-1987 the level of infestation of adult bovines increased, in average, with 22.3% and of young cattle with 18.6% which prove the existence of various outbreaks of parasitic agents (definitive hosts) and lack or irregular conducting of dehelmentization. It was determined that the infested with echinococcosis cattle produce less meat and eatable by-products. Moreover, the content of some vitamins (A, E, B1, B2, C), micro-, macroelements (Ca, Mg, Na, K, Fe, P), chemical indicies (humidity, dry solid matter, proteins, fat, mineral saults) in muscular and liver tussues proved to be considerably changed influencing considerably the animal products’ nutrition value