Comparison of data on Mutation Frequencies of Mice Caused by Radiation - Low Dose Model -

We propose LD(Low Dose) model, the extension of LDM model which was proposed in the previous paper [Y. Manabe et al.: J. Phys. Soc. Jpn. 81 (2012) 104004] to estimate biological damage caused by irradiation. LD model takes account of all the considerable effects including cell death effect as well as proliferation, apoptosis, repair. As a typical example of estimation, we apply LD model to the experiment of mutation frequency on the responses induced by the exposure to low levels of ionizing radiation. The most famous and extensive experiments are those summarized by Russell and Kelly [Russell, W. L. & Kelly, E. M: Proc. Natl Acad. Sci. USA 79 (1982) 539-541], which are known as 'Mega-mouse project'. This provides us with important information of the frequencies of transmitted specific-locus mutations induced in mouse spermatogonia stem-cells. It is found that the numerical results of the mutation frequency of mice are in reasonable agreement with the experimental data: the LD model reproduces the total dose and dose rate dependence of data reasonably. In order to see such dose-rate dependence more explicitly, we introduce the dose-rate effectiveness factor (DREF). This represents a sort of preventable effects such as repair, apoptosis and death of broken cells, which are to be competitive with proliferation effect of broken cells induced by irradiation.Comment: subimitting to J. Phys. Soc. Jpn, 32 pages, 8 figure

A range expanding signal conditioner

Telemetry system modifications to improve signal resolution are described. Process uses zero suppression technique which consists of subtracting known voltage from input and amplifying remainder. Schematic diagram of circuit is provided and details of operation are presented

Perceptions of Blame in Intimate Partner Violence: The Role of the Perpetrator\u27s Ability to Arouse Fear of Injury in the Victim

Men are more likely to be blamed more for intimate partner violence (IPV) than are women who commit the same offense. However, because men are typically stronger and perceived as more physically aggressive than women are, perpetrator sex is confounded with masculinity and the ability to arouse fear in the victim. This study disentangled the construct of gender in understanding bystanders’ attributions of blame in IPV. Participants (N = 639) read a scenario in which the perpetrator’s sex (male/female) and gender identity (masculine/feminine), and the victim’s sex (male/female) were manipulated and rated how much they blamed the perpetrator and the perpetrator’s ability to arouse fear of injury in the victim. Results showed that male perpetrators (regardless of gender identity) who assaulted a female victim were attributed the most blame and were perceived as having the greatest ability to arouse victim fear. In contrast, feminine female perpetrators were attributed the least blame and perceived as arousing the least victim fear regardless of the victim’s gender. Furthermore, controlling for the perpetrator’s ability to arouse fear in the victim resulted in the elimination of the interaction effects for blame. This finding suggests that perpetrators’ ability to arouse fear is an underlying factor in bystanders’ attributions of blame

Hydrogen film cooling of a small hydrogen-oxygen thrust chamber and its effect on erosion rates of various ablative materials

An experimental investigation was conducted to determine what arrangement of film-coolant-injection orifices should be used to decrease the erosion rates of small, high temperature, high pressure ablative thrust chambers without incurring a large penalty in combustion performance. All of the film cooling was supplied through holes in a ring between the outer row of injector elements and the chamber wall. The best arrangement, which had twice the number of holes as there were outer row injection elements, was also the simplest. The performance penalties, presented as a reduction in characteristic exhaust velocity efficiency, were 0.8 and 2.8 percentage points for the 10 and 20 percent cooling flows, respectively, The best film-coolant injector was then used to obtain erosion rates for 19 ablative materials. The throat erosion rate was reduced by a factor of 2.5 with a 10 percent coolant flow. Only the more expensive silica phenolic materials had low enough erosion rates to be considered for use in the nozzle throat. However, some of the cheaper materials might qualify for use in other areas of small nozzles with large throat diameters where the higher erosion rates are more acceptable

UA3/3/1 Founders Day, November 11, 1964: A Brief Tribute

Founders Day speech written and presented by M.W. Russell. Original found in President Kelly Thompson\u27s papers

Fiber optic control system integration

A total fiber optic, integrated propulsion/flight control system concept for advanced fighter aircraft is presented. Fiber optic technology pertaining to this system is identified and evaluated for application readiness. A fiber optic sensor vendor survey was completed, and the results are reported. The advantages of centralized/direct architecture are reviewed, and the concept of the protocol branch is explained. Preliminary protocol branch selections are made based on the F-18/F404 application. Concepts for new optical tools are described. Development plans for the optical technology and the described system are included

Impact of Ranch and Market Factors on an Index of Agricultural Holding Period Returns

This study develops nominal and real holding period return indices for operating ranches. The indices contain two components, monthly ranch operating profit and capital appreciation. A regression model that determines the effect of various attributes on total market value is used to estimate capital appreciation, and a second model determines operating profit. The two different ranch data series are compared with United States Long Term Government Bonds, the S&P 500 Index and Small Capitalization Stocks. Both ranch indices show very low correlation with the S&P 500 Index and very low or negative betas. Further, both ranch series have excess actual nominal and real returns when compared to expected returns determined from the Capital Asset Pricing Model.

Dynamics of trusses having nonlinear joints

The transient analysis of trusses having nonlinear joints can be accomplished using the residual force technique. The technique was applied a two degree of freedom spring mass system, a four bay planar truss, and an actual ten bay deployable truss. Joints chosen for analysis were the nonlinear gap joints and the linear Voigt joints. Results from the nonlinear gap analyses generally indicate that coupling between the modes can display some interesting effects during free vibration. One particularly interesting effect was that the damping of the structure appeared to be higher than could be accounted for from modal damping alone. Energy transferral from the lower to the higher modes was found to exist as a result of the modal coupling. The apparently increased damping was due to the fact that the energy transferred to the higher modes is inherently dissipated more quickly. Another interesting phenomenon was that the lower modes could drive the higher modes even during free vibration and that these modes could display a rather large quasi-steady state behavior even when modal damping was present. Gaps were also found to increase the amplitude and period of the free vibration response as expected

Genetic Locus and Structural Characterization of the Biochemical Defect in the O-Antigenic Polysaccharide of the Symbiotically Deficient \u3cem\u3eRhizobium etli\u3c/em\u3e Mutant, CE166

The O-antigen polysaccharide (OPS) of Rhizobium etli CE3 lipopolysaccharide (LPS) is linked to the core oligosaccharide via an N-acetylquinovosaminosyl (QuiNAc) residue. A mutant of CE3, CE166, produces LPS with reduced amounts of OPS, and a suppressed mutant, CE166α, produces LPS with nearly normal OPS levels. Both mutants are deficient in QuiNAc production. Characterization of OPS from CE166 and CE166α showed that QuiNAc was replaced by its 4-keto derivative, 2-acetamido-2,6-dideoxyhexosyl-4-ulose. The identity of this residue was determined by NMR and mass spectrometry, and by gas chromatography-mass spectrometry analysis of its 2-acetamido-4-deutero-2,6-dideoxyhexosyl derivatives produced by reduction of the 4-keto group using borodeuteride. Mass spectrometric and methylation analyses showed that the 2-acetamido-2,6-dideoxyhexosyl-4-ulosyl residue was 3-linked and attached to the core-region external Kdo III residue of the LPS, the same position as that of QuiNAc in the CE3 LPS. DNA sequencing revealed that the transposon insertion in strain CE166 was located in an open reading frame whose predicted translation product, LpsQ, falls within a large family of predicted open reading frames, which includes biochemically characterized members that are sugar epimerases and/or reductases. A hypothesis to be tested in future work is that lpsQ encodes UDP-2-acetamido-2,6-dideoxyhexosyl-4-ulose reductase, the second step in the synthesis of UDP-QuiNAc from UDP-GlcNAc