3,775 research outputs found
Letter from Charles Russell to Frank Linderman, 5 November 1917
Letter from Charles Russell to Frank Linderman, dated 5 November 1917. The letter acknowledges an upcoming visit by Russell to Summers [possibly Somers, Montana] and discusses a missing knife.https://scholarworks.umt.edu/whicker/1014/thumbnail.jp
Critical Perspective: The Unnatural Nature of the Animal Rights/Liberation Philosophy
Author Institution: Department of Integrative Biology and Cancer Research Laboratory, University of California at Berkele
Modeling of fuel-to-steel heat transfer in core disruptive accidents
"June 1980."Also issued as a Ph. D. thesis by the first author, MIT Dept. of Nuclear Engineering, 1980Includes bibliographical references (pages 110-111)A mathematical model for direct-contact boiling heat transfer between immiscible fluids was developed and tested experimentally. The model describes heat transfer from a hot fluid bath to an ensemble of droplets of a cooler fluid that boils as it passes through the hot fluid. The mathematical model is based on single bubble correlations for the heat transfer and a drift-flux model for the fluid dynamics. The model yields a volumetric heat transfer coefficient as a function of the initial diameter, velocity and volume fraction of the dispersed component. An experiment was constructed to boil cyclopentane droplets in water. The mathematical and experimental results agreed reasonably well. The results were applied to investigate the possibility of steel vaporization during a hypothetical core disruptive accident in a liquid metal fast breeder reactor. The model predicts that substantial steel vaporization may occur in core disruptive accidents, if the steel reaches its saturation temperature rapidly enough. The potential importance of steel vaporization is dependent on the accident scenario.Report issued under contract with the U.S. Nuclear Regulatory Commission NRC-04-77-12
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Synaptic connections of hilar basal dendrites of dentate granule cells in a neonatal hypoxia model of epilepsy.
Numerous animal models of epileptogenesis demonstrate neuroplastic changes in the hippocampus. These changes occur not only for the mature neurons and glia, but also for the newly generated granule cells in the dentate gyrus. One of these changes, the sprouting of mossy fiber axons, is derived predominantly from newborn granule cells in adult rats with pilocarpine-induced temporal lobe epilepsy. Newborn granule cells also mainly contribute to another neuroplastic change, hilar basal dendrites (HBDs), which are synaptically targeted by mossy fibers in the hilus. Both sprouted mossy fibers and HBDs contribute to recurrent excitatory circuitry that is hypothesized to be involved in increased seizure susceptibility and the development of spontaneous recurrent seizures (SRS) that occur following the initial pilocarpine-induced status epilepticus. Considering the putative role of these neuroplastic changes in epileptogenesis, a critical question is whether similar anatomic phenomena occur after epileptogenic insults to the immature brain, where the proportion of recently born granule cells is higher due to ongoing maturation. The current study aimed to determine if such neuroplastic changes could be observed in a standardized model of neonatal seizure-inducing hypoxia that results in development of SRS. We used immunoelectron microscopy for the immature neuronal marker doublecortin to label newborn neurons and their HBDs following neonatal hypoxia. Our goal was to determine whether synapses form on HBDs from neurons born after neonatal hypoxia. Our results show a robust synapse formation on HBDs from animals that experienced neonatal hypoxia, regardless of whether the animals experienced tonic-clonic seizures during the hypoxic event. In both cases, the axon terminals that synapse onto HBDs were identified as mossy fiber terminals, based on the appearance of dense core vesicles. No such synapses were observed on HBDs from newborn granule cells obtained from sham animals analyzed at the same time points. This aberrant circuit formation may provide an anatomic substrate for increased seizure susceptibility and the development of epilepsy
Events leading up to the June 2015 outburst of V404 Cyg
On 2015 June 15 the burst alert telescope (BAT) on board {\em Swift} detected
an X-ray outburst from the black hole transient V404 Cyg. We monitored V404 Cyg
for the last 10 years with the 2-m Faulkes Telescope North in three optical
bands (V, R, and i). We found that, one week prior to this outburst, the
optical flux was 0.1--0.3 mag brighter than the quiescent orbital modulation,
implying an optical precursor to the X-ray outburst. There is also a hint of a
gradual optical decay (years) followed by a rise lasting two months prior to
the outburst. We fortuitously obtained an optical spectrum of V404 Cyg 13 hours
before the BAT trigger. This too was brighter () than
quiescence, and showed spectral lines typical of an accretion disk, with
characteristic absorption features of the donor being much weaker. No He II
emission was detected, which would have been expected had the X-ray flux been
substantially brightening. This, combined with the presence of intense
H emission, about 7 times the quiescent level, suggests that the disk
entered the hot, outburst state before the X-ray outburst began. We propose
that the outburst is produced by a viscous-thermal instability triggered close
to the inner edge of a truncated disk. An X-ray delay of a week is consistent
with the time needed to refill the inner region and hence move the inner edge
of the disk inwards, allowing matter to reach the central BH, finally turning
on the X-ray emission.Comment: Accepted by ApJ Letter, 7 pages, 5 figure
The Drosophila genome nexus: a population genomic resource of 623 Drosophila melanogaster genomes, including 197 from a single ancestral range population.
Hundreds of wild-derived Drosophila melanogaster genomes have been published, but rigorous comparisons across data sets are precluded by differences in alignment methodology. The most common approach to reference-based genome assembly is a single round of alignment followed by quality filtering and variant detection. We evaluated variations and extensions of this approach and settled on an assembly strategy that utilizes two alignment programs and incorporates both substitutions and short indels to construct an updated reference for a second round of mapping prior to final variant detection. Utilizing this approach, we reassembled published D. melanogaster population genomic data sets and added unpublished genomes from several sub-Saharan populations. Most notably, we present aligned data from phase 3 of the Drosophila Population Genomics Project (DPGP3), which provides 197 genomes from a single ancestral range population of D. melanogaster (from Zambia). The large sample size, high genetic diversity, and potentially simpler demographic history of the DPGP3 sample will make this a highly valuable resource for fundamental population genetic research. The complete set of assemblies described here, termed the Drosophila Genome Nexus, presently comprises 623 consistently aligned genomes and is publicly available in multiple formats with supporting documentation and bioinformatic tools. This resource will greatly facilitate population genomic analysis in this model species by reducing the methodological differences between data sets
Establishment and Management of Old World Bluestem Grasses for Seed
The Oklahoma Agricultural Experiment Station periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311
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