Patient Education Visuals Communicating the Role of Salpingectomy in the Primary Prevention of Ovarian Cancer

Epithelial ovarian cancer is one of the most lethal gynecologic malignancies, affecting 1 in 80 women, with fewer than 50% surviving five years after diagnosis. Approximately 90% of cases originate in the fallopian tubes (Lheureux et al., 2019). In 2015, the American College of Obstetricians and Gynecologists (ACOG) recommended bilateral salpingectomy as the standard of care for ovarian cancer prevention during surgical sterilization and hysterectomy (Committee on Gynecologic Practice 2015). Despite this, patient awareness of salpingectomy and its preventive benefits remains limited. Existing reproductive health and pregnancy prevention resources fail to distinguish between, or even include, salpingectomy and tubal ligation, contributing to confusion and missed opportunities for cancer prevention. For the first time, salpingectomy-centered education was integrated into a comprehensive suite of multimedia resources, framed through patient perspective and guided by the lens of ovarian cancer prevention rather than pregnancy prevention alone. These materials were designed for patient use, with particular attention to visual clarity, accessible language, and cultural responsiveness. Development was informed by clinical shadowing, IRB-approved workshop participation, and collaboration with OB/GYN providers, legal advisors, and patient education specialists. All resources were translated into Spanish to expand accessibility. The prototypes developed include: 1) a 2D animation (ninety seconds) explaining the link between contraception and ovarian cancer risk; 2) three versions of comprehensive posters about contraception, juxtaposing pregnancy prevention and ovarian cancer risk reduction; 3) a trifold brochure contrasting salpingectomy with tubal ligation; 4) a Unity-based interactive module with manipulable 3D models of female reproductive anatomy; 5) a plain-language glossary with a simplified definition and pronunciation guide for forty relevant terms; and 6) the first procedure-specific surgical consent forms for salpingectomy and tubal ligation, approved for implementation at Johns Hopkins Hospital. Developed with iterative feedback from patients and providers, these educational resources offer a scalable model for improving informed consent and lifelong reproductive health education. Future work will involve formal user feedback to assess impact and to support continued refinement. Together, these resources represent a novel, patient-centered advancement in ovarian cancer education. They offer opportunities to create actionable awareness about the benefits of salpingectomy for ovarian cancer prevention for all

Patient Education Visuals Communicating the Role of Salpingectomy in the Primary Prevention of Ovarian Cancer

Epithelial ovarian cancer is one of the most lethal gynecologic malignancies, affecting 1 in 80 women, with fewer than 50% surviving five years after diagnosis. Approximately 90% of cases originate in the fallopian tubes (Lheureux et al., 2019). In 2015, the American College of Obstetricians and Gynecologists (ACOG) recommended bilateral salpingectomy as the standard of care for ovarian cancer prevention during surgical sterilization and hysterectomy (Committee on Gynecologic Practice 2015). Despite this, patient awareness of salpingectomy and its preventive benefits remains limited. Existing reproductive health and pregnancy prevention resources fail to distinguish between, or even include, salpingectomy and tubal ligation, contributing to confusion and missed opportunities for cancer prevention. For the first time, salpingectomy-centered education was integrated into a comprehensive suite of multimedia resources, framed through patient perspective and guided by the lens of ovarian cancer prevention rather than pregnancy prevention alone. These materials were designed for patient use, with particular attention to visual clarity, accessible language, and cultural responsiveness. Development was informed by clinical shadowing, IRB-approved workshop participation, and collaboration with OB/GYN providers, legal advisors, and patient education specialists. All resources were translated into Spanish to expand accessibility. The prototypes developed include: 1) a 2D animation (ninety seconds) explaining the link between contraception and ovarian cancer risk; 2) three versions of comprehensive posters about contraception, juxtaposing pregnancy prevention and ovarian cancer risk reduction; 3) a trifold brochure contrasting salpingectomy with tubal ligation; 4) a Unity-based interactive module with manipulable 3D models of female reproductive anatomy; 5) a plain-language glossary with a simplified definition and pronunciation guide for forty relevant terms; and 6) the first procedure-specific surgical consent forms for salpingectomy and tubal ligation, approved for implementation at Johns Hopkins Hospital. Developed with iterative feedback from patients and providers, these educational resources offer a scalable model for improving informed consent and lifelong reproductive health education. Future work will involve formal user feedback to assess impact and to support continued refinement. Together, these resources represent a novel, patient-centered advancement in ovarian cancer education. They offer opportunities to create actionable awareness about the benefits of salpingectomy for ovarian cancer prevention for all

Inside

Acrylic paint on a wood panelhttps://trace.tennessee.edu/utk_libsartf13/1009/thumbnail.jp

Clypeaster

Drywall Compound and Acrylic on Canvashttps://trace.tennessee.edu/utk_libsarts15/1001/thumbnail.jp

On the Occurrence of Cicindela fera Chevrolat in the United States (Coleoptera-Cicindelidae)

Volume: 10Start Page: 55End Page: 5

Automatisierte Erstellung von Simulationsmodellen für einen fasergewickelten Drucktank in Creo/Simulate unter Verwendung der VB-Schnittstelle

Für die Simulation eines fasergewickelten Drucktanks werden die Ergebnisdaten einer Wickelsimulation, bestehend aus Geometrieinformationen und lokalen Wickelwinkeln, von denen wiederum die Materialeigenschaften und die erforderliche Messgrößen abhängen, automatisch in ein Creo-Simulationsmodell unter Verwendung der VB-Schnittstelle umgesetzt. Weiter wird auf die Auswertung der Ergebnisse eingegangen

A new species of Cicindela from Idaho (Coleoptera: Cicindelidae)

Volume: 35Start Page: 129End Page: 14

Note On Cicindela longilabris Say (Coleoptera, Cicindelidae)

Volume: 90Start Page: 55End Page: 5

Tiger beetles of the genus Cicindela in the Sulpher Springs Valley, Arizona, with descriptions of three new subspecies (CicindelidaeColeoptera)

Volume: 41Start Page: 169End Page: 18

Chlamydia psittaci elementary body envelopes: ingestion and inhibition of phagolysosome fusion

The cell surface of Chlamydia psittaci seems important for establishing infection since (i) UV-treated elementary bodies (EB) attach to and are ingested by L cells and (ii) heat or antibody treatment decreases attachment to L cells and promotes the fusion of chlamydiae-containing phagosomes with lysosomes in macrophages. In the studies reported here, [3H]uridine-labeled UV-treated EB also persisted in mouse resident peritoneal macrophages and L cells, suggesting that phagosome-lysosome fusion is inhibited. We therefore chose to investigate the ingestion and internal fate of isolated purified EB envelopes in both nonprofessional and professional phagocytic cells. EB envelopes are internalized by target host cells as efficiently as are whole EB. Transmission electron microscopy of macrophages whose lysosomes were marked with ferritin revealed the persistence of individual envelopes in phagosomes devoid of ferritin for the 3-h observation period. In contrast, EB envelopes heated to 56 degrees C for 15 min were consistently found in ferritin-labeled phagolysosomes as early as 30 min. As another index of persistence, isolated EB envelopes were radioisotopically labeled with a Bolton-Hunter analog, [3H]N-succinimidyl propionate, and their fate as trichloroacetic acid-precipitable material was followed. A third probe, employed to detect the persistence of non-biodegradable antigen, was indirect immunofluorescence. Fluorescein-positive antigens were brightly visible for 7 days in both macrophages and L cells when they were inoculated with untreated EB or EB maintained in penicillin. But L cells inoculated with EB envelopes or EB treated with UV or chloramphenicol, all of which prevent the conversion of infectious EB into the metabolically active reticulate bodies, displayed reduced internal fluorescence by 2 days and the appearance of fluorescent material on the cell surface. This release of EB envelope material occurred in the absence of phagolysosome fusion. The data add credence to the belief that the spontaneous breakdown or autolytic enzyme release of EB envelope components must occur preparatory to the conversion of EB to reticulate bodies.</jats:p