Reconfigurable phase-change optical metasurfaces: novel design concepts to practicable devices

Optical metasurfaces have been proven to be capable of controlling amplitude, phase and polarization of optical beams without the need of bulky geometries, making them really attractive for the development of compact photonic devices. Recently, their combination with chalcogenide phase-change materials (traditionally employed in non-volatile optical and electrical memories), whose refractive index can be reversibly and repeatedly controlled, has been proposed to yield low power consumption tunable metasurfaces having several functionalities in a single device. However, despite phase-change memories are commercially available since various decades now, the unification of phase-change materials with metasurfaces towards real life applications is becoming a formidable task, mainly due to the several engineering branches involved in this technology, which sometimes compromise each other in a non-trivial way. This includes thermo/optical, thermo/electric, and chemical incompatibilities which are typically not taken into account by researchers working in the field, resulting in devices having exciting reconfigurable properties, but at the same time, lack of practicability. This thesis is therefore dedicated to the development of novel phase-change metasurface architectures which could partially or totally address such engineering problems. Particular emphasis has been put in the realization of reconfigurable metasurfaces for active wavefront control, as such a functionality remains relatively unexplored. The first part of this thesis focuses in the first experimental demonstration of active, reconfigurable non-mechanical beam steering devices working the near-infrared. This was achieved via integration of ultra-thin films of chalcogenide phase-change materials (in this case, the widely employed alloy Ge2Sb2Te5) within the body of a dielectric spacer in a plasmonic metal/insulator/metal metasurface architecture. Active, and optically reversible beam steering between two different angles with efficiencies up to 40% were demonstrated. The second part of this work shows the work carried out in metal-free metasurfaces as a way to manipulate optical beams with high efficiency in both transmission and/or reflection. This was achieved via combination of all-dielectric silicon nanocylinders with deeply-subwavelenght sized Ge2Sb2Te5 inclusions. By strategic placement of the phase-change inclusions in the regions of high electric field density, independent and active control of the metasuface resonances is demonstrated, with modulations depths as high as 70% and 65% in reflection and transmission respectively. Multilevel, and fully reversible optically-induced switching of the phasechange layer is also reported, with up to 11 levels of tunability over 8 switching cycles. Finally, the last section of this thesis introduces the concept of hybrid dielectric/plasmonic phase-change metasurfaces having key functional benefits when compared to both purely dielectric and plasmonic approaches. The proposed architectures showed great versatility in terms of both active amplitude and phase control, offering the possibility of designing devices for different purposes (i.e. such as active absorbers/modulators or beam steerers with enhanced efficiency) employing the same unit-cell configuration with minor geometry re-optimizations. Initial device experimental demonstrations of such an approach are discussed, as well as their potential in terms of delivering in-situ electrical switching capabilities using a metallic ground plane as a resistive heater.Engineering and Physical Sciences Research Council (EPSRC

Phase-change metasurfaces for dyamic beam steering and beam shaping in the infrared

This is the author accepted manuscript. The final version is available from the publisher via the DOI in this recordWe present novel phase-change material based metasurfaces for dynamic, recnofigurable and efficient wavefront shaping in the infrared spectrum. Dynamic control and reconfigurability was obtained by incorporating an ultra-thin layer of the widely-used phase change material Ge2Sb2Te5. Our approach exploits hybrid dielectic/plasmonic resonances to achieve local (subwavelength) phase control of light with low losses. A full 2π optical phase coverage was achieved with this approach, which allows for a wide flexibility in terms of realizable designs. To illustrate this concept, dynamic beam steering devices and reconfigurable planar focusing mirrors (both operating at optical telecommunications wavelengths) and their performance investigated. Absolute efficiencies up to 65% are achieved, significantly higher than the efficiencies of more commonly reported plasmonic-based phase-change metasurfaces.CDW acknowledges funding via the US Naval Research Laboratories ONRG programme (#N62909-16-1-2174) and the EPSRC ChAMP and WAFT grants (EP/M015130/1 and EP/M015173/1). CRdeG acknowledges funding via the EPSRC CDT in Metamaterials (EP/L015331/1). CRdeG Acknowledges Joaquin Faneca-Ruedas and Dr Anna Baldycheva

Infrared Phase-Change Meta-Devices with In-Situ Switching

This is the author accepted manuscript. The final version is available from the European Phase Change and Ovonics Symposium via the link in this recordWe describe a possible device design approach and an experimental test platform suitable for the realization and characterization of phase-change based meta-devices incorporating in-situ switching and operating at infrared wavelengths. Measurements on such a prototype device working at 1.55 µm are presented.US Naval Research LaboratoriesEngineering and Physical Sciences Research Council (EPSRC

All-dielectric hybrid silicon/Ge2Sb2Te5 optical metasurfaces for tunable and switchable light control in the near infrared

This is the final version.We report a novel reconfigurable metasurface based on the combination of all-dielectric arrays of silicon meta-atoms, with deeply subwavelength (< λ0/150) Ge2Sb2Te5 layers. Our approach allows to selectively and individually control electric and magnetic resonances.Engineering and Physical Sciences Research Council (EPSRC

Lithography-free fabrication of extraordinary transmission plasmonic metasurfaces over large areas employing ultrafast lasers

This is the author accepted manuscript. The final version is available from IEEE via the DOI in this recordPlasmonic metasurfaces based on the extraordinary optical transmission effect (EOT) can be deliberately designed to efficiently transmit specific spectral bands from the visible to the long-infrared regimes, but can also provide high electric field confinement in regions much smaller than the operation wavelength [1] . Such nano/microphotonic devices (which, as shown in Fig. 1(a) , consist of subwavelength periodically or randomly arranged apertures on ultrathin metallic films) could therefore find applications in important technological fields such as compact multispectral imaging, biosensing, transmissive colour displays, non-linear optics or enhancement of the Raman signal. However, due to their subwavelength nature, fabrication of EOT metasurfaces operating in the visible and infrared spectral regimes is typically conducted through expensive, micro- and nanofabrication techniques carried out in strict cleanroom environments. Therefore, patterning of large areas required for applications currently dominated by conventional optical elements are translated into several fabrication steps and long lithography writing times: procedures that significantly increase the operation cost and energy consumption to a non-acceptable level for most industrial entities.Engineering and Physical Sciences Research Council (EPSRC

Plasmonically-enhanced all-optical integrated phase-change memory

This is the final version. Available on open access from the Optical Society of America via the DOI in this record.Integrated phase-change photonic memory devices offer a novel route to non-volatile storage and computing that can be carried out entirely in the optical domain, obviating the necessity for time and energy consuming opto-electrical conversions. Such memory devices generally consist of integrated waveguide structures onto which are fabricated small phase-change memory cells. Switching these cells between their amorphous and crystalline states modifies significantly the optical transmission through the waveguide, so providing memory, and computing, functionality. To carry out such switching, optical pulses are sent down the waveguide, coupling to the phase-change cell, heating it up, and so switching it between states. While great strides have been made in the development of integrated phase-change photonic devices in recent years, there is always a pressing need for faster switching times, lower energy consumption and a smaller device footprint. In this work, therefore, we propose the use of plasmonic enhancement of the light-matter interaction between the propagating waveguide mode and the phase-change cell as a means to faster, smaller and more energy-efficient devices. In particular, we propose a form of plasmonic dimer nanoantenna of significantly sub-micron size that, in simulations, offers significant improvements in switching speeds and energies. Write/erase speeds in the range 2 to 20 ns and write/erase energies in the range 2 to 15 pJ were predicted, representing improvements of one to two orders of magnitude when compared to conventional device architectures.Engineering and Physical Sciences Research Council (EPSRC

Choice of the initial antiretroviral treatment for HIV-positive individuals in the era of integrase inhibitors

BACKGROUND: We aimed to describe the most frequently prescribed initial antiretroviral therapy (ART) regimens in recent years in HIV-positive persons in the Cohort of the Spanish HIV/AIDS Research Network (CoRIS) and to investigate factors associated with the choice of each regimen. METHODS: We analyzed initial ART regimens prescribed in adults participating in CoRIS from 2014 to 2017. Only regimens prescribed in >5% of patients were considered. We used multivariable multinomial regression to estimate Relative Risk Ratios (RRRs) for the association between sociodemographic and clinical characteristics and the choice of the initial regimen. RESULTS: Among 2874 participants, abacavir(ABC)/lamivudine(3TC)/dolutegavir(DTG) was the most frequently prescribed regimen (32.1%), followed by tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC)/elvitegravir(EVG)/cobicistat(COBI) (14.9%), TDF/FTC/rilpivirine (RPV) (14.0%), tenofovir alafenamide (TAF)/FTC/EVG/COBI (13.7%), TDF/FTC+DTG (10.0%), TDF/FTC+darunavir/ritonavir or darunavir/cobicistat (bDRV) (9.8%) and TDF/FTC+raltegravir (RAL) (5.6%). Compared with ABC/3TC/DTG, starting TDF/FTC/RPV was less likely in patients with CD4100.000 copies/mL. TDF/FTC+DTG was more frequent in those with CD4100.000 copies/mL. TDF/FTC+RAL and TDF/FTC+bDRV were also more frequent among patients with CD4<200 cells//muL and with transmission categories other than men who have sex with men. Compared with ABC/3TC/DTG, the prescription of other initial ART regimens decreased from 2014-2015 to 2016-2017 with the exception of TDF/FTC+DTG. Differences in the choice of the initial ART regimen were observed by hospitals' location. CONCLUSIONS: The choice of initial ART regimens is consistent with Spanish guidelines' recommendations, but is also clearly influenced by physician's perception based on patient's clinical and sociodemographic variables and by the prescribing hospital location

Phase-Change Meta-Optics with Enhanced Efficiency

This is the author accepted manuscript.The use of thin Ge2Sb2Te5 layers in combination with hybrid dielectric/plasmonic metasurfaces is discussed as a way to create reconfigurable flat optics in the optical telecommunication regime. Our approach shows good potential in the development of high efficiency, compact and ultra-fast optical components for current free-space optical telecommunication systems.Engineering and Physical Sciences Research Council (EPSRC

Effectiveness of the combination elvitegravir/cobicistat/tenofovir/emtricitabine (EVG/COB/TFV/FTC) plus darunavir among treatment-experienced patients in clinical practice : A multicentre cohort study

Background: The aim of this study was to investigate the effectiveness and tolerability of the combination elvitegravir/cobicistat/tenofovir/emtricitabine plus darunavir (EVG/COB/TFV/FTC + DRV) in treatment-experienced patients from the cohort of the Spanish HIV/AIDS Research Network (CoRIS). Methods: Treatment-experienced patients starting treatment with EVG/COB/TFV/FTC + DRV during the years 2014-2018 and with more than 24 weeks of follow-up were included. TFV could be administered either as tenofovir disoproxil fumarate or tenofovir alafenamide. We evaluated virological response, defined as viral load (VL) < 50 copies/ml and < 200 copies/ml at 24 and 48 weeks after starting this regimen, stratified by baseline VL (< 50 or ≥ 50 copies/ml at the start of the regimen). Results: We included 39 patients (12.8% women). At baseline, 10 (25.6%) patients had VL < 50 copies/ml and 29 (74.4%) had ≥ 50 copies/ml. Among patients with baseline VL < 50 copies/ml, 85.7% and 80.0% had VL < 50 copies/ml at 24 and 48 weeks, respectively, and 100% had VL < 200 copies/ml at 24 and 48 weeks. Among patients with baseline VL ≥ 50 copies/ml, 42.3% and 40.9% had VL < 50 copies/ml and 69.2% and 68.2% had VL < 200 copies/ml at 24 and 48 weeks. During the first 48 weeks, no patients changed their treatment due to toxicity, and 4 patients (all with baseline VL ≥ 50 copies/ml) changed due to virological failure. Conclusions: EVG/COB/TFV/FTC + DRV was well tolerated and effective in treatment-experienced patients with undetectable viral load as a simplification strategy, allowing once-daily, two-pill regimen with three antiretroviral drug classes. Effectiveness was low in patients with detectable viral loads