77 research outputs found

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    Tese de mestrado integrado. Engenharia Electrotécnica e de Computadores (Major Telecomunicações). Faculdade de Engenharia. Universidade do Porto. 201

    Dynamic network tariffs: are they the most efficient way to match peak consumption and network incremental costs?

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    The purpose of this paper is to present the main results of the ongoing analysis of applying dynamic network access tariffs in Portugal. For the 2015-2017 regulatory period, the Portuguese National Regulatory Authority, ERSE, required the three main Portuguese DSOs to submit, until the end of June 2016, plans for the implementation of network dynamic tariff schemes targeting Medium, High and Extra High Voltage customers, as well as the respective cost-benefit analysis. EDP Distribuição, the main Portuguese DSO, is preparing a report regarding the implementation of pilot projects on a sample of these segments of customers, which are due to be on the field during 2017. These pilots should help electrical energy stakeholders understand how the Electric System can benefit from the use of dynamic tariffs focused on networks, allowing for the quantification of benefits in a more accurate way. The level of demand response that results from price signals is a key issue that both the regulator and EDP Distribuição will quantify. Other important issue to assess in this study is the efficiency of cost recovery under a dynamic tariff scheme. In conclusion, this paper will present some results obtained from the cost-benefit analysis regarding the implementation of a Critical Peak Pricing scheme, as well as the key learnings supporting the introduction of dynamic schemes in the future, not only for EHV, HV and MV customers but also eventually extending it to LV ones

    CO053. O IMPACTO DOS ANDROGÉNIOS NA RESISTÊNCIA ÓSSEA DE HOMENS NORMAIS.

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    Innovative reactor prototype for Hydrogen production in a stationary application using sodium borohydride

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    Hydrogen storage has proved to be the greatest obstacle preventing hydrogen from replacing fossil fuels. Hence, a safe, efficient and economical method of storing hydrogen must be available to turn viable a hydrogen economy based on renewable resources [1]. Hydrogen can be stored in chemical hydrides such as sodium borohydride (NaBH4), with large theoretical H2 content of 10,9 wt%. With the aid of catalysts, and at room temperatures, the alkaline hydrolysis of NaBH4 can be enhanced [2]. In this work, a 100 L innovative reactor for hydrogen production was designed, based on the optimized layout of a laboratorial scale reactor [3], as part of a project financed by the Portuguese financial support program NSRF. The developed system has the capability to feed a 5 kW PEM fuel cell with a maximum hydrogen consumption of 75 slpm. The NaBH4 solution is stored in a 50 L reservoir from where seven consecutive 7,0 L injections to the reactor are possible. The Ni-Ru based catalyst applied can be re-used several times without losing its performance [1] and because of this capacity its replacement will be done, manually, every seven NaBH4 solution injections (simultaneously with the residual solution removal and the reactor cleaning). The catalyst should then be recovered for further utilization. Additionally to the reactor, a 400 to 500 L reservoir was also designed to be used as the system buffer since the reactor works in batch mode and it is desired that the PEMFC operates continuously. The system was conceived for stationary applications and eventually to be installed in remote areas, reason why the systemś monitoring and control are fully automatized. Its hydropneumatic circuit layout is characterized by four parts: injection system, reactor, valves bloc and buffer. It is assumed that the designed system can operate continuously throughout 15 hours with a medium hydrogen consumption of 10 slpm, which can supply a daily household energy power demand

    REVISÃO SISTEMATIZADA SOBRE TRANSPORTE PÚBLICO NO BRASIL E NO MUNDO UTILIZANDO A BASE SCOPUS

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    O objetivo deste trabalho é realizar uma revisão sistematizada, que possibilite gerar debates e identificar o estado da arte sobre o tema “transporte público” utilizando a base Scopus para verificar as tendências e a evolução das publicações. Na pesquisa, foi observado que o primeiro artigo data de 1945 e que, a partir do ano 2000, o número de artigos cresceu exponencialmente, chegando a 740, em 2016. Os países que mais publicaram sobre o tema foram Reino Unido (13,9%) e Estados Unidos (9,3%). O Brasil ocupa atualmente a 17ª lugar no ranking, com 1,5% dos artigos publicados no mundo. A instituição “The University of Sydney” foi a que mais publicou artigos (152), seguida da “Delft University os Technology” (102). No Brasil, o destaque é para a Universidade de São Paulo, com 18 artigos publicados. Foi realizado também o levantamento dos principais autores, periódicos e áreas de publicação

    Combining inflammatory miRNA molecules as diagnostic biomarkers for depression: a clinical study

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    BackgroundInflammation has been implicated in core features of depression pathophysiology and treatment resistance. Therefore, new challenges in the discovery of inflammatory mediators implicated in depression have emerged. MicroRNAs (miRNAs) have been found aberrantly expressed in several pathologies, increasing their potential as biomarkers and therapeutical targets. In this study, the aim was to assess the changes and biomarker potential of inflammation-related miRNAs in depression patients.MethodsDepression diagnosis was performed according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). 40 healthy controls and 32 depression patients were included in the study. The levels of inflammatory cytokines were measured in plasma, and expression levels of cytokines and inflammation-related miRNAs were evaluated in peripheral blood mononuclear cells (PBMCs).ResultsDepression patients were found to have a pro-inflammatory profile in plasma, with significantly higher levels of TNF-α and CCL2 compared with controls. In PBMCs of depression patients, TNF-α and IL-6 expression levels were significantly up and downregulated, respectively. Moreover, miR-342 levels were found upregulated, while miR-146a and miR-155 were significantly downregulated. miR-342 expression levels were positively correlated with TNF-α. Importantly, when analyzed as a diagnostic panel, receiver operating characteristics (ROC) analysis of miR-342, miR-146a, miR-155 in combination, showed to be highly specific and sensitive in distinguishing between depression patients and healthy controls.ConclusionIn summary, these findings suggest that inflammation-related miRNAs are aberrantly expressed in depression patients. Moreover, we show evidences on the potential of the combination of dysregulated miRNAs as a powerful diagnostic tool for depression
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