565 research outputs found
IR Thermography for Non-Destructive Monitoring of Moisture in Cultural Heritage
One of the main sources of damage to historical buildings is the presence of humidity. It is fundamental to develop a diagnosis protocol to identify the presence of water, evaluate the damage in a building (the whole structure, part of it or individual materials), assess its vulnerability and, finally, carry out a restoration plan. IR thermography is a sustainable method to guarantee structure analysis and preservation. Here, an application is presented, permitting us to identify the wet and dry areas and transition zone related to evaporation on the surface of the investigated materials. Thanks to temperature maps, it is possible to observe saturated regions, qualitatively at first and then quantitatively, processing the images by plotting reference lines/points and correlating surface temperatures with moisture
Systematic evaluation of sequential geostatistical resampling within MCMC for posterior sampling of near-surface geophysical inverse problems
We critically examine the performance of sequential geostatistical resampling (SGR) as a model proposal mechanism for Bayesian Markov-chain-Monte-Carlo (MCMC) solutions to near-surface geophysical inverse problems. Focusing on a series of simple yet realistic synthetic crosshole georadar tomographic examples characterized by different numbers of data, levels of data error and degrees of model parameter spatial correlation, we investigate the efficiency of three different resampling strategies with regard to their ability to generate statistically independent realizations from the Bayesian posterior distribution. Quite importantly, our results show that, no matter what resampling strategy is employed, many of the examined test cases require an unreasonably high number of forward model runs to produce independent posterior samples, meaning that the SGR approach as currently implemented will not be computationally feasible for a wide range of problems. Although use of a novel gradual-deformation-based proposal method can help to alleviate these issues, it does not offer a full solution. Further, we find that the nature of the SGR is found to strongly influence MCMC performance; however no clear rule exists as to what set of inversion parameters and/or overall proposal acceptance rate will allow for the most efficient implementation. We conclude that although the SGR methodology is highly attractive as it allows for the consideration of complex geostatistical priors as well as conditioning to hard and soft data, further developments are necessary in the context of novel or hybrid MCMC approaches for it to be considered generally suitable for near-surface geophysical inversion
Effector-Specific Characterization of Brain Dynamics in Manual vs. Oculomotor Go/NoGo Tasks.
Motor inhibitory control (IC), the ability to suppress unwanted actions, has been previously shown to rely on domain-general IC processes that are involved in a wide range of IC tasks. Nevertheless, the existence of effector-specific regions and activation patterns that would differentiate manual vs. oculomotor response inhibition remains unknown. In this study, we investigated the brain dynamics supporting these two response effectors with the same IC task paradigm. We examined the behavioral performance and electrophysiological activity in a group of healthy young people (n = 25) with a Go/NoGo task using the index finger for the manual modality and the eyes for the oculomotor modality. By computing topographic analysis of variance, we found significant differences between topographies of scalp recorded potentials of the two response effectors between 250 and 325 ms post-stimulus onset. The source estimations localized this effect within the left precuneus, a part of the superior parietal lobule, showing stronger activity in the oculomotor modality than in the manual modality. Behaviorally, we found a significant positive correlation in response time between the two modalities. Our collective results revealed that while domain-general IC processes would be engaged across different response effectors in the same IC task, effector-specific activation patterns exist. In this case, the stronger activation of the left precuneus likely accounts for the increased demand for visual attentional processes in the oculomotor Go/NoGo task
Regional-scale integration of multiresolution hydrological and geophysical data using a two-step Bayesian sequential simulation approach
Significant progress has been made with regard to the quantitative integration of geophysical and hydrological data at the local scale for the purpose of improving predictions of groundwater flow and solute transport. However, extending corresponding approaches to the regional scale still represents one of the major challenges in the domain of hydrogeophysics. To address this problem, we have developed a regional-scale data integration methodology based on a two-step Bayesian sequential simulation approach. Our objective is to generate high-resolution stochastic realizations of the regional-scale hydraulic conductivity field in the common case where there exist spatially exhaustive but poorly resolved measurements of a related geophysical parameter, as well as highly resolved but spatially sparse collocated measurements of this geophysical parameter and the hydraulic conductivity. To integrate this multi-scale, multi-parameter database, we first link the low- and high-resolution geophysical data via a stochastic downscaling procedure. This is followed by relating the downscaled geophysical data to the high-resolution hydraulic conductivity distribution. After outlining the general methodology of the approach, we demonstrate its application to a realistic synthetic example where we consider as data high-resolution measurements of the hydraulic and electrical conductivities at a small number of borehole locations, as well as spatially exhaustive, low-resolution estimates of the electrical conductivity obtained from surface-based electrical resistivity tomography. The different stochastic realizations of the hydraulic conductivity field obtained using our procedure are validated by comparing their solute transport behaviour with that of the underlying "true” hydraulic conductivity field. We find that, even in the presence of strong subsurface heterogeneity, our proposed procedure allows for the generation of faithful representations of the regional-scale hydraulic conductivity structure and reliable predictions of solute transport over long, regional-scale distance
Multimodal Argument Mining: A Case Study in Political Debates
We propose a study on multimodal argument mining in the domain of political debates. We collate and extend existing corpora and provide an initial empirical study on multimodal architectures, with a special emphasis on input encoding methods. Our results provide interesting indications about future directions in this important domain
ADAM10 Localization in Temporomandibular Joint Disk with Internal Derangement: An Ex Vivo Immunohistochemical Study
The purpose of this study was to determine the presence of ADAM10 in temporomandibular joint disk with internal derangement. Twenty-five paraffin blocks of displaced temporomandibular joint (TMJ) disk specimens from earlier investigations were retrieved from the archives of the University of Catania. Of these 16 had been removed from females and 9 from males; 11 with anterior disk displacement with reduction (ADDwR) and 14 with anterior disk displacement without reduction (ADDwoR). The sections were dehydrated, embedded in paraffin and cut. Then they were incubated in 0.3% H2O2/methanol and half of sections from each sample were incubated in diluted rabbit polyclonal anti-ADAM10 antibody. Then biotinylated anti-mouse/anti-rabbit IgG was applied to the sections, followed by avidin–biotin–perioxidase complex. The results were analyzed and the results were that ADAM10 was overexpressed in the posterior band of sections from patients with ADDwR compared to the other bands of both ADDwR and ADDwoR sections. Overexpression correlated with severe histopathological degeneration. We believe these results have the potential to provide insights into the pathogenesis of TMJ disk degeneration and to help design new therapeutic approaches targeting the proteolytic events that lead to tissue degeneration. Early therapeutic block of ADAM10 activity could succeed in limiting aggrecan-rich matrix breakdown without affecting normal physiology
Pattern of antibiotic consumption in two Italian production chains differing by the endemic status for Porcine Reproductive and Respiratory Syndrome
The aim of this case study was to quantify antibiotic (AB) use in Italian weaning (W) and fattening (F) units differentiated for porcine reproductive and respiratory syndrome (PRRS) occurrence. Farms were classified as either PRRS negative (–) or PRRS positive (+) based on the circulation of the virus among the animals. In all the farms, the modified live PRRS virus (PRRSV) vaccine was provided to all the animals. In the PRRS– farms, the level of circulating antibodies was low, and the disease, in its clinical form, did not occur. In the PRRS+ farms, the level of circulating antibodies against the virus was high, and the disease was recurrent. Data regarding AB consumption were collected from 2017 to 2020, and the active compounds (ACs) were expressed as milligrams of AC/total kilogram of body weight (BW) produced. Each AC was classified into one of four categories according to the EuropeanMedicines Agency classification of ABs for prudent and responsible use in animals: Avoid, Restrict, Caution, and Prudence. Data regarding the ACs in each category were analyzed using a linear model that included production phase, PRRS status, and their interaction as factors. Performance parameters, average age of the pigs at the end of each phase, daily live weight gain, feed-to-gain ratio, total losses, cost index, and medication costs were significantly influenced by the PRRS chain. The use of class B ABs was not affected by production phase or PRRS status. Conversely, for class C ABs, interaction between the two factors (p = 0.02) was observed; W/PRRS+ and F/PRRS+ showed the greatest AB use for this class
(p = 0.003). For class D ABs, the interaction was significant (p = 0.01); class C and D ABs were used more in the weaning (p = 0.07) than in the fattening phase (p = 0.003). For the weaning phase, the use of class C and D ABs was greater in the PRRS+ than in the PRRS– chain (p < 0.01). In conclusion, PRRS status affected the growth of pigs and economic performance. Moreover, PRRS status significantly influenced the use of ABs during all the growing periods with the greatest impact being on the weaning phase
Building renovation : Which kind of guidelines could be proposed for policy makers and professional owners?
IEA IBC Annex 56 methodology provides the basis for the assessment and evaluation of energy related renovation options of residential building stock, first and foremost with respect to cost, energy use and carbon emissions. Furthermore, it allows also for a broader approach going beyond cost effective reduction of carbon emissions and energy use by taking into account co-benefits achieved in a renovation process. Besides impact indicators for primary energy use, carbon emissions and costs it also provides a methodological framework for integrating at least embodied energy use for renovation measures as part of a lifecycle impact assessment. The methodology and resulting fundamentals for renovation standards have to be applicable to different climatic and country specific situations. The Guideline for policy makers proposed by the Annex 56 gives useful information and suggestions to the drafting of legislative and administrative measures, at the national or local level, for reducing the amount of energy consumption and greenhouse gas emissions in renovation of residential buildings. The reachable saving targets must be defined in agreement with the actors in the energy market, as the owners and / or the managers of buildings, but policy makers must be aware of their responsibility in defining cost effective levels for nearly zero energy or emissions building renovation, using a life cycle perspective, and the relevance of preparing adequate financial packages to support ambitious levels for building renovation. Furthermore, the
Guideline for professional owners shall report outlines key drivers for building retrofit and use and the resulting impacts on energy consumption. This Guideline shall describe building and energy efficiency trends specific to the residential building sectors
Design and verification of a micro wells turbine for Mediterranean operations
In the framework of the Poseidone Project we have designed a Wells turbine for Mediterranean
operations. Here we present RANS computations carried out with OpenFOAM at different
operating conditions. Rotor-stator interaction was synthetized with MRF approach and RANS
closure relied on the cubic eddy viscosity closure of Lien et al. The virtual test rig reproduced
the ISO conditions of the laboratory and was able to correctly predict torque and efficiency at
different operations. Computations moreover allowed to acquire information on the threedimensional
velocity and pressure field that develops inside the Wells turbine. The aim was to
have an insight on the secondary motions and on the possible stall mechanism that characterize
the device at low flow rates. Results were successfully validated against experimental measures
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