Theoretical shape of the magnetosphere boundary taking into account the geomagnetic dipole inclination to the geographic axis and the non-dipole part of the geomagnetic field

Theoretical shape of magnetosphere boundary considering inclination of geomagnetic dipole and nondipole part of geomagnetic fiel

Public survey instruments for business administration using social network analysis and big data

Purpose: The subject matter of this research is closely intertwined with the scientific discussion about the necessity of developing and implementing practice-oriented means of measuring social well-being taking into account the intensity of contacts between individuals. The aim of the research is to test the toolkit for analyzing social networks and to develop a research algorithm to identify sources of consolidation of public opinion and key agents of influence. The research methodology is based on postulates of sociology, graph theory, social network analysis and cluster analysis. Design/Methodology/Approach: The basis for the empirical research was provided by the data representing the reflection of social media users on the existing image of Russia and its activities in the Arctic, chosen as a model case. Findings: The algorithm allows to estimate the density and intensity of connections between actors, to trace the main channels of formation of public opinion and key agents of influence, to identify implicit patterns and trends, to relate information flows and events with current information causes and news stories for the subsequent formation of a "cleansed" image of the object under study and the key actors with whom this object is associated. Practical Implications: The work contributes to filling the existing gap in the scientific literature, caused by insufficient elaboration of the issues of applying the social network analysis to solve sociological problems. Originality/Value: The work contributes to filling the existing gap in the scientific literature formed as a result of insufficient development of practical issues of using analysis of social networks to solve sociological problems.peer-reviewe

Intimate Partner Violence, Perception of Safety, and Faith Among Female College Students Attending Faith-Based Institutions

Many women experience intimate partner violence (IPV), and research shows this violence significantly impacts their mental health, physical health, and substance abuse. The experience of IPV may also impact other areas of life. This study aims to explore the relationship between the experiences of IPV, perception of safety, and perception of faith, among female college students attending Christian universities. Archival data from the National College Health Assessment (NCHA) was used to explore this relationship among female students who experienced physical, sexual, or psychological IPV in the past twelve months. Results indicate students who experienced IPV endorsed lower perceptions of safety than their counterparts who did not experience IPV. In addition, results failed to find that faith moderated the perception of safety among students who have experienced IPV

State Youth Policy as Factor of Youth Welfare

This study demonstrates an attempt to build up the system of criteria for assessing the effectiveness of the youth policy implementation in education institutions and special organs. The assessing is underpinned by several criteria. These criteria are: criterion of matching priorities of youth policy expectations and the young people needs, criterion of consistency of priorities in forming and implementing national and regional youth policy, criterion of consistency work of various regional and local organizations and social institutions, criterion for mental and physical health of young people, criterion of the general level of development of social activity of youth, the level of youth`s crime

Titanium Carbide: Nanotechnology, Properties, Application

The paper develops scientific and technological bases for fabrication of titanium carbide which is a nanocomponent of composite materials. The authors determine optimum technology specifications and the main titanium carbide properties: fineness of titaniferous raw materials, carbide-forming agent quantity, set temperature of plasma flow, tempering temperature, titanium carbide yield, productivity, specific surface, size and shape of particles. The paper includes equations to describe how the major specifications of the fabrication technique influence the content of titanium carbide and free carbon in the end product

Computational approaches for identifying somatic intergenic mutations of relevance in cancer

Cancer is a complex genomic disease characterized by accumulation of somatic mutations over the lifetime of a patient. Identification of somatic driver mutations that contribute to tumorigenesis is a major goal of cancer genomics. With the recent advances in the sequencing technologies it became possible to study somatic mutations on the whole-genome scale in multiple cancers. While most of the cancer genomics studies were previously focused on identification of driver mutations affecting exons, several examples of driver events within the non-protein-coding regions of the genome were identified, including the recurrent TERT promoter mutations. Such findings have spurred searches for similar examples of recurrent non-coding mutations using computational cancer genomics. In my PhD thesis, I present several computational approaches aimedto identify somatic driver mutations with a specific focus on intergenic regions of the genome. The first part of this thesis focuses on the somatic mutational patterns along the cancer genome and addresses a fundamental problem of computational identification of recurrently mutated regions – regional mutational heterogeneity. Here I studied the correlation of specific genomic features with background somatic mutation rates and devised a background model that accounts for regional mutational heterogeneity. The second part of this thesis describes three different computational approaches designed to identify somatic driver events of functional relevance in cancer. The first approach integrates somatic mutation calls with gene expression data to identify variants associated with altered mRNA levels. The second approach is designed to predict changes in transcription factor binding sites in presence of recurrent somatic mutations. The third approach uses cross-validation scheme to enable parameter tuning in screens for recurrently somatically mutated regions in cancer genomes in an unbiased genome-wide manner. Using this approach, we identify several known cancer-relevant targets, both exonic (e.g., the TP53, MYC, and SMARCA4 genes) as well as non-coding regulatory regions (e.g., the TERT promoter) and uncover novel candidate regulatory driver regions. Among those, a cluster of recurrent intergenic mutations, occurring in an enhancer element near the FADS2 gene, which encodes a critical enzyme in the biosynthesis of long chain polyunsaturated fatty acids and has been previously implicated in cancer. Collectively, the computational approaches presented here helped in uncovering novel somatic candidate events of relevance in cancer and can be further used for various applications in cancer genomics

Синдром Блоха — Сульцбергера

The author describes a rare case of dermatosis in children — incontinentia pigmenti. The author also describes manifestations characteristic of the Bloch — Sulzberger syndrome. All stages of the disease are presented in detail.Приведены случаи редкого дерматоза у детей — синдром недержания пигмента. Описаны характерные проявления синдрома Блоха — Сульцбергера. Подробно представлены все стадии заболевания

FEATURES OF PARTICIPATION OF RUSSIA IN THE WORLD MARKET OF OIL DURING THE PERIOD FROM 1992 TO 2013 IN THE CONTEXT OF THE FAVORABLE PRICE ENVIRONMENT

In the article influence of the favorable price environment is analyzed in the world market of oil on production and export of oil in Russia during the pre-sanctions period with use of the retrospective analysis on the basis of the statistical data from 1992 to 2013. The particular emphasis is placed on the stimulating function of the price in the conditions of its growth inducing to speeding up of production and export of power raw materials. The author refers loss of sensitivity to price signals at the present stage to aspect of strategy of repartition of the world market of oil, for preservation of positions on which Russia should be overcome