36 research outputs found
Диагностика глубокой перипротезной инфекции тазобедренного сустава
Periprosthetic infection (PJI) is one of the most frequent and devastating complications of total hip arthroplasty (THA). Early and accurate diagnosis of PJI allows timely initiation of treatment. Various diagnostic tools and algorithms for hip PJI diagnosis are described. The available serum (ESR, CRP, D-dimer, etc.) and synovial (alpha-defensin, leukocyte esterase, D-lactate) biomarkers are listed, as well as their combinations for the purpose of PJI verification. Combined serum and synovial tests can significantly improve the efficiency of PJI hip diagnosis.Перипротезная инфекция (ППИ) является одним из наиболее частых и разрушительных осложнений эндопротезирования тазобедренного сустава (ТБС). Ранняя и точная диагностика ППИ позволяет своевременно начать лечение. Описаны различные диагностические инструменты и алгоритмы диагностики ППИ ТБС. Перечислены имеющиеся сывороточные (СОЭ, СРБ, D-димер и др.) и синовиальные (альфа-дефенсин, лейкоцитарная эстераза, D-лактат) биомаркеры, а также их комбинации с целью верификации ППИ. Объединение сывороточных и синовиальных тестов позволяет значительно повысить эффективность диагностики ППИ ТБС
Development of a pulsed bremsstrahlung source on a base of a nanosecond and microsecond REB accelerators
In the paper the preliminary results on measuring parameters of a pulsed bremsstrahlung source developed for
investigation of physical-mechanical properties of reactor materials are given. Generation of γ-radiation with
parameters γ ∼ 0.4...1.0 MeV was carried out at microsecond and nanosecond high-current REB accelerators. The
absolute values of an absorbed dose are determined for both nanosecond and microsecond sources of γ-radiation.Приведено попередні результати по вимірюванню параметрів імпульсного джерела гальмованого
випромінювання, якій створюється для дослідження фізико-механічних властивостей матеріалів
реакторобудівництва. Генерація НЖР-випромінювання з параметрами 0,4<γ<1,0 МеВ здійснювалась
мікросекундному і наносекундному сильнострумових прискорювачах РЕП. Визначені абсолютні значення
дози поглинання, як для наносекундного, так і мікросекундного джерел γ-випромінювання.Приведены предварительные результаты по измерениям параметров импульсного источника тормозного
излучения, создаваемого для исследования физико-механических свойств материалов реакторостроения. Генерация СЖР излучения с параметрами 0,4<γ<1,0 МэВ осуществлялась на микросекундном и наносекундном сильноточных ускорителях РЭП. Определены абсолютные значения поглощенной дозы, как для наносекундного так и микросекундного источников γ-излучения
An influence of pretreatment conditions on surface structure and reactivity of Pt(100) towards CO oxidation reaction
On the Stability of ZrO2 + TiO2 Coatings on Titanium Formed by Plasma Electrolytic Oxidation in a Chlorine-Containing Medium
Early Paleozoic magmatism in the Bumbat-Hairhan area of the Lake Zone in western Mongolia (geological, petrochemical, and geochronological data)
Antitumor enzyme L-lyzine-α-oxidase from Trichoderma harzianum Rifai F-180 and investigation of its action on L-lysine oxidation by capillar electrophoresis
Trichoderma harzianum Rifai F-180, an organism producing the antitumor enzyme L-lysine-a-oxidase was cultivated and the enzyme was isolated and purified under the manufacturing conditions. The effect of L-lysine-α-oxidase on oxidation of L-lysine was investigated for the first time by capillary electrophoresis and the procedure conditions were developed. The reaction of L-lysine oxidative deamination is described and location of the reaction components picks on the elecrophoregrams was identified. The average rate of the catalytic reaction of L-lysine oxidation equal to 0.46 RU/min (7.7×103 RU/sec) was determined. The use of the antitumor enzyme L-lysine-a-oxidase is recommended as a drug for the treatment of superficial tumors and tissue relative oxygen excess
Antitumor enzyme L-lyzine-α-oxidase from Trichoderma harzianum Rifai F-180 and investigation of its action on L-lysine oxidation by capillar electrophoresis
Trichoderma harzianum Rifai F-180, an organism producing the antitumor enzyme L-lysine-a-oxidase was cultivated and the enzyme was isolated and purified under the manufacturing conditions. The effect of L-lysine-α-oxidase on oxidation of L-lysine was investigated for the first time by capillary electrophoresis and the procedure conditions were developed. The reaction of L-lysine oxidative deamination is described and location of the reaction components picks on the elecrophoregrams was identified. The average rate of the catalytic reaction of L-lysine oxidation equal to 0.46 RU/min (7.7×103 RU/sec) was determined. The use of the antitumor enzyme L-lysine-a-oxidase is recommended as a drug for the treatment of superficial tumors and tissue relative oxygen excess