2,971 research outputs found
A pilot search for mm-wavelength recombination lines from emerging ionized winds in pre-planetary nebulae candidates
We report the results from a pilot search for radio recombination line (RRL)
emission at millimeter wavelengths in a small sample of pre-planetary nebulae
(pPNe) and young PNe (yPNe) with emerging central ionized regions. Observations
of the H30\alpha, H31a, H39a, H41a, H48b, H49b, H51b, and H55g lines at 1 and
3mm have been performed with the IRAM 30 m radio telescope. These lines are
excellent probes of the dense inner (<~150 au) and heavily obscured regions of
these objects, where the yet unknown agents for PN-shaping originate. We
detected mm-RRLs in three objects: CRL 618, MWC 922, and M 2-9. For CRL 618,
the only pPN with previous published detections of H41a, H35a, and H30a
emission, we find significant changes in the line profiles indicating that
current observations are probing regions of the ionized wind with larger
expansion velocities and mass-loss rate than ~29 years ago. In the case of MWC
922, we observe a drastic transition from single-peaked profiles at 3mm to
double-peaked profiles at 1mm, which is consistent with maser amplification of
the highest frequency lines; the observed line profiles are compatible with
rotation and expansion of the ionized gas, probably arranged in a disk+wind
system around a ~5-10 Msun central mass. In M 2-9, the mm-RRL emission appears
to be tracing a recent mass outburst by one of the stars of the central binary
system. We present the results from non-LTE line and continuum radiative
transfer models, which enables us to constrain the structure, kinematics, and
physical conditions (electron temperature and density) of the ionized cores of
our sample. (abridged). We deduce mass-loss rates of ~1e-6-1e-7 Msun/yr, which
are significantly higher than the values adopted by stellar evolution models
currently in use and would result in a transition from the asymptotic giant
branch to the PN phase faster than hitherto assumed.Comment: Accepted by Astronomy and Astrophysics. 28 pages, including figure
High Excitation Molecular Gas in the Magellanic Clouds
We present the first survey of submillimeter CO 4-3 emission in the
Magellanic Clouds. The survey is comprised of 15 6'x6' maps obtained using the
AST/RO telescope toward the molecular peaks of the Large and Small Magellanic
Clouds. We have used these data to constrain the physical conditions in these
objects, in particular their molecular gas density and temperature. We find
that there are significant amounts of molecular gas associated with most of
these molecular peaks, and that high molecular gas temperatures are pervasive
throughout our sample. We discuss whether this may be due to the low
metallicities and the associated dearth of gas coolants in the Clouds, and
conclude that the present sample is insufficient to assert this effect.Comment: 18 pages, 3 figures, 5 tables. To appear in Ap
Evaluation of Fluorescent Confocal Microscopy for Intraoperative Analysis of Prostate Biopsy Cores
The use of fluorescent confocal microscopy allows fast and easy preparation of biopsy cores for intraoperative analysis. We observed strong concordance with traditional analysis in our study. The role of this technique is yet to be established
Optical excitations in organic molecules, clusters and defects studied by first-principles Green's function methods
Spectroscopic and optical properties of nanosystems and point defects are
discussed within the framework of Green's function methods. We use an approach
based on evaluating the self-energy in the so-called GW approximation and
solving the Bethe-Salpeter equation in the space of single-particle
transitions. Plasmon-pole models or numerical energy integration, which have
been used in most of the previous GW calculations, are not used. Fourier
transforms of the dielectric function are also avoided. This approach is
applied to benzene, naphthalene, passivated silicon clusters (containing more
than one hundred atoms), and the F center in LiCl. In the latter, excitonic
effects and the defect line are identified in the energy-resolved
dielectric function. We also compare optical spectra obtained by solving the
Bethe-Salpeter equation and by using time-dependent density functional theory
in the local, adiabatic approximation. From this comparison, we conclude that
both methods give similar predictions for optical excitations in benzene and
naphthalene, but they differ in the spectra of small silicon clusters. As
cluster size increases, both methods predict very low cross section for
photoabsorption in the optical and near ultra-violet ranges. For the larger
clusters, the computed cross section shows a slow increase as function of
photon frequency. Ionization potentials and electron affinities of molecules
and clusters are also calculated.Comment: 9 figures, 5 tables, to appear in Phys. Rev. B, 200
SEOM clinical guideline in ovarian cancer (2020)
Despite remarkable advances in the knowledge of molecular biology and treatment, ovarian cancer remains the leading cause of death from gynecologic cancer. In the last decade, there have been important advances both in systemic and surgical treatment. However, there is no doubt that the incorporation of PARP inhibitors as maintenance after the response to platinum-based chemotherapy, first in recurrent disease and recently also in first line, will change the natural history of the disease. The objective of this guide is to summarize the current evidence for the diagnosis, treatment, and follow-up of ovarian cancer, and to provide evidence-based recommendations for clinical practice
From favorable atomic configurations to supershell structures: a new interpretation of conductance histograms
Title: From favorable atomic configurations to supershell structures: a new
interpretation of conductance histograms Authors: A. Hasmy (IVIC), E. Medina
(IVIC), P.A. Serena (CSIC,IVIC) Comments: 7 pages, 3 figures,
cond-mat.anwar.10825 Subj-class: Soft Condensed MatterComment: 7 pages, 3 figuresSubject: fput HMS.tex HMS-FIG1.ps HMS-FIG2.ps
HMS-FIG3.p
On the Stability and Structural Dynamics of Metal Nanowires
This article presents a brief review of the nanoscale free-electron model,
which provides a continuum description of metal nanostructures. It is argued
that surface and quantum-size effects are the two dominant factors in the
energetics of metal nanowires, and that much of the phenomenology of nanowire
stability and structural dynamics can be understood based on the interplay of
these two competing factors. A linear stability analysis reveals that metal
nanocylinders with certain magic conductance values G=1, 3, 6, 12, 17, 23, 34,
42, 51, 67, 78, 96, ... times the conductance quantum are exceptionally stable.
A nonlinear dynamical simulation of nanowire structural evolution reveals a
universal equilibrium shape consisting of a magic cylinder suspended between
unduloidal contacts. The lifetimes of these metastable structures are also
computed.Comment: 8 pages, 6 figure
pNaKtide Attenuates Steatohepatitis and Atherosclerosis by Blocking Na/K-ATPase/ROS Amplification in C57BI6 and ApoE Knockout Mice Fed a Western Diet
We have previously reported that the alpha1 subunit of sodium potassium adenosine triphosphatase (Na/K-ATPase), acts as a receptor and an amplifier for reactive oxygen species, in addition to its distinct pumping function. On this background, we speculated that blockade of Na/K-ATPase-induced ROS amplification with a specific peptide, pNaKtide, might attenuate the development of steatohepatitis. To test this hypothesis, pNaKtide was administered to a murine model of NASH: the C57Bl6 mouse fed a western diet containing high amounts of fat and fructose. The administration of pNaKtide reduced obesity as well as hepatic steatosis, inflammation and fibrosis. Of interest, we also noted marked improvement in mitochondrial fatty acid oxidation, insulin sensitivity, dyslipidemia and aortic streaking in this mouse model. To further elucidate the effects of pNaKtide on atherosclerosis, similar studies were performed in ApoE knockout mice also exposed to the western diet. In these mice, pNaKtide not only improved steatohepatitis, dyslipidemia, and insulin sensitivity, but also ameliorated significant aortic atherosclerosis. Collectively, this study demonstrates that the Na/K-ATPase/ROS amplification loop contributes significantly to the development and progression of steatohepatitis and atherosclerosis. And furthermore, this study presents a potential treatment, the pNaKtide, for the metabolic syndrome phenotype
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