Improving the accessibility and re-use of environmental models through provision of model metadata : a scoping study

This poster presents the results of a scoping study funded under a recent Natural Environment Research Council (NERC) Environmental Data Call. The work was undertaken by the British Geological Survey (Nottinghamshire, UK) in collaboration with HR Wallingford (Oxfordshire, UK). This investigation was designed to better understand the problem that whilst the input data used for modelling frequently has metadata data available, and metadata is often routinely created for the datasets created by modelling, there was perceived to be a lack of schemes and systems to record metadata about the modelling process itself. From this analysis gaps in metadata provision were identified, and recommendations for further work to address these were identified

How strong are salt marshes? Geotechnical properties of coastal wetland soils

Funder: British Geological Survey; Id: http://dx.doi.org/10.13039/501100002760This paper compares two marshes of contrasting sedimentology at Tillingham marsh, eastern England, and Warton marsh, North West England. Soil shear strength and compressibility are determined by applying geotechnical methods to determine marsh resistance to shear- and vertical effective- stresses. This research was able to isolate the influence of roots on substrate shear strength in a three-dimensional sample. In response to vertical effective stress, both the expected displacement magnitude and the vertical recovery potential of a marsh substrate are affected by past stress conditions on the marsh, particularly those resulting from desiccation. The substrate response to vertical effective stress also influences substrate shear strength through the effect of consolidation on the void ratio (or bulk density)

The association between protease inhibitors and anal cancer outcomes in veterans living with HIV treated with definitive chemoradiation: a retrospective study

Background: The incidence of anal squamous cell carcinoma has been increasing, particularly in people living with HIV (PLWH). There is concern that radiosensitizing drugs, such as protease inhibitors, commonly used in the management of HIV, may increase toxicities in patients undergoing chemoradiation. This study examines treatment outcomes and toxicities in PLWH managed with and without protease inhibitors who are receiving chemoradiation for anal cancer. Methods: Patient demographic, HIV management, and cancer treatment information were extracted from multiple Veterans Affairs databases. Patients were also manually chart reviewed. Among PLWH undergoing chemoradiation for anal carcinoma, therapy outcomes and toxicities were compared between those treated with and without protease inhibitors at time of cancer treatment. Statistical analysis was performed using chi-square, Cox regression analysis, and logistic regression. Results: A total of 219 PLWH taking anti-retroviral therapy undergoing chemoradiation for anal cancer were identified and included in the final analysis. The use of protease inhibitors was not associated with any survival outcome including colostomy-free survival, progression-free survival, or overall survival (all adjusted hazard ratio p-values\u3e 0.05). Regarding toxicity, protease inhibitor use was not associated with an increased odds of hospitalizations or non-hematologic toxicities; however, protease inhibitor use was associated with increased hospitalizations for hematologic toxicities, including febrile neutropenia (p \u3c 0.01). Conclusion: The use of protease inhibitors during chemoradiation for anal carcinoma was not associated with any clinical outcome or increase in non-hematologic toxicity. Their use was associated with increased hospitalizations for hematologic toxicities. Further prospective research is needed to evaluate the safety and efficacy of protease inhibitors for patients undergoing chemoradiation

Training in critical care echocardiography

Echocardiography is useful for the diagnosis and management of hemodynamic failure in the intensive care unit so that competence in some elements of echocardiography is a core skill of the critical care specialist. An important issue is how to provide training to intensivists so that they are competent in the field. This article will review issues related to training in critical care echocardiography

Anomalous buried hollows in London: development of a hazard susceptibility map

Engineering works carried out in central London over many decades have revealed a number of buried hollows that exhibit curious characteristics. Some extend deep into the bedrock geology and are in-filled with disturbed superficial deposits and reworked bedrock. Others are contained within the superficial deposits. They can be up to 500 m wide and more than 60 m in depth. As the infill material often has different behavioural characteristics from the surrounding deposits failure to identify them during an initial site investigation can prove costly. This paper considers their common characteristics and describes the method used to develop a buried hollow hazard susceptibility map. This map provides planners with a broader awareness of the potential location of difficult ground conditions associated with them, thereby reducing the potential for unforeseen ground conditions through effective site investigation design. The paper continues with a discussion of some of the likely processes associated with their formation, which are attributed to cryogenic processes, and concludes with potential future research directions

Short term outcomes of total arterial coronary revascularization in patients above 65 years: a propensity score analysis

<p>Abstract</p> <p>Background</p> <p>Despite the advantages of bilateral mammary coronary revascularization, many surgeons are still restricting this technique to the young patients. The objective of this study is to demonstrate the safety and potential advantages of bilateral mammary coronary revascularization in patients older than 65 years.</p> <p>Methods</p> <p>Group I included 415 patients older than 65 years with exclusively bilateral mammary revascularization. Using a propensity score we selected 389 patients (group II) in whom coronary bypass operations were performed using the left internal mammary artery and the great saphenous vein.</p> <p>Results</p> <p>The incidence of postoperative stroke was higher in group II (1.5% vs. 0%, P = 0.0111). The amount of postoperative blood loss was higher in group I (908 ± 757 ml vs. 800 ± 713 ml, P = 0.0405). There were no other postoperative differences between both groups.</p> <p>Conclusion</p> <p>Bilateral internal mammary artery revascularization can be safely performed in patients older than 65 years. T-graft configuration without aortic anastomosis is particularly beneficial in this age group since it avoids aortic manipulation, which is an important risk factor for postoperative stroke.</p

Keeping it Real : An Evaluation Audit of Five Years of Youth-led Program Evaluation

Youth are increasingly seen as competent in participating in research and program evaluation, two activities previously reserved for adults. This paper is a report of the findings from an evaluation audit of Stand Up! Help Out!, a participatory action after-school youth leadership development program for disadvantaged urban youth that utilized youth evaluations to develop a best practices service model. The youths’ feedback assisted providers in improving services so that youth engagement in the program was 99% (by comparison with national highs of 79%). Here, we describe an important aspect of the process of youth-led program evaluation leading to such high youth engagement: How youth interviewed each other so as to optimize the authenticity of their program evaluations and contributions to program design. Drawing from over five years of program evaluation data collected by youth, the authors report on the youths’ experiences as informants and co-researchers, consider strategies used to help youth best describe their experiences in the program, and describe implications for other settings looking to incorporate youth-led program evaluation. Youth-led program evaluation has considerable promise for helping service providers make programs more meaningful for disadvantaged youth

Unofficial policy: access to housing, housing information and social services among homeless drug users in Hartford, Connecticut

BACKGROUND: Much research has shown that the homeless have higher rates of substance abuse problems than housed populations and that substance abuse increases individuals' vulnerability to homelessness. However, the effects of housing policies on drug users' access to housing have been understudied to date. This paper will look at the "unofficial" housing policies that affect drug users' access to housing. METHODS: Qualitative interviews were conducted with 65 active users of heroin and cocaine at baseline, 3 and 6 months. Participants were purposively sampled to reflect a variety of housing statuses including homeless on the streets, in shelters, "doubled-up" with family or friends, or permanently housed in subsidized, unsubsidized or supportive housing. Key informant interviews and two focus group interviews were conducted with 15 housing caseworkers. Data were analyzed to explore the processes by which drug users receive information about different housing subsidies and welfare benefits, and their experiences in applying for these. RESULTS: A number of unofficial policy mechanisms limit drug users' access to housing, information and services, including limited outreach to non-shelter using homeless regarding housing programs, service provider priorities, and service provider discretion in processing applications and providing services. CONCLUSION: Unofficial policy, i.e. the mechanisms used by caseworkers to ration scarce housing resources, is as important as official housing policies in limiting drug users' access to housing. Drug users' descriptions of their experiences working with caseworkers to obtain permanent, affordable housing, provide insights as to how access to supportive and subsidized housing can be improved for this population