84 research outputs found
"It doesn't do any harm, but patients feel better": a qualitative exploratory study on gastroenterologists' perspectives on the role of antidepressants in inflammatory bowel disease
Background: Interest in psychological factors in patients with inflammatory bowel disease (IBD) has increased in recent years. It has even been proposed that treating psychological co-morbidities with antidepressants may control disease activity and improve quality of life. Despite this, there is no data on gastroenterologists' attitudes to, and experiences with, antidepressant therapy in patients with IBD. Methods: We conducted semi-structured interviews with 18 gastroenterologists associated with metropolitan teaching hospitals. Qualitative content analysis was used to examine their responses. Results: Seventy-eight percent of gastroenterologists had treated IBD patients with antidepressants for pain, depression and/or anxiety, and insomnia. Antidepressants were reported to be useful in improving psychosocial well-being, quality of life, and self-management of the disease by patients. However, in this group of gastroenterologists, there appears to be skepticism towards psychological disorders themselves or antidepressant therapy having a central role in either the causation of IBD or its clinical course. Nevertheless, these gastroenterologists were receptive to the idea of conducting a trial of the role of antidepressants in IBD. Conclusion: While the majority of specialists have treated IBD patients with antidepressants, there is considerable skepticism with regard to efficacy of antidepressive therapy or the role of psychological factors in the outcome of IBD patients.Antonina A Mikocka-Walus, Deborah A Turnbull, Nicole T Moulding, Ian G Wilson, Jane M Andrews and Gerald J Holtman
Techniques avancées de traitement du signal pour les systÚmes de distribution quantique de clés sur fibre optique basés sur des variables continues.
Quantum key distribution offers the possibility of cryptography whose security is demonstrated by the laws of quantum physics. The first commercial systems of this technology are now available. This thesis focuses on continuous variable protocols, whose practical implementation is close to modern digital transmission techniques over optical fibers. By exploiting these techniques, we realize an experimental system for high speed continuous variable quantum key distribution.La distribution quantique de clĂ©s offre la possibilitĂ© dâune cryptographie dont la sĂ©curitĂ© est dĂ©montrĂ©e par les lois de la physique quantique. De premiers systĂšmes commerciaux de cette technologie sont aujourdâhui disponibles. Cette thĂšse sâintĂ©resse plus particuliĂšrement aux protocoles Ă variables continues, dont lâimplĂ©mentation pratique sâapproche des techniques modernes de transmissions numĂ©riques sur fibre optique. En exploitant ces techniques, on rĂ©alise un systĂšme expĂ©rimental de distribution quantique de clĂ©s Ă variables continues Ă haut dĂ©bit
Techniques avancées de traitement du signal pour les systÚmes de distribution quantique de clés sur fibre optique basés sur des variables continues
Quantum key distribution offers the possibility of cryptography whose security is demonstrated by the laws of quantum physics. The first commercial systems of this technology are now available. This thesis focuses on continuous variable protocols, whose practical implementation is close to modern digital transmission techniques over optical fibers. By exploiting these techniques, we realize an experimental system for high speed continuous variable quantum key distribution.La distribution quantique de clĂ©s offre la possibilitĂ© dâune cryptographie dont la sĂ©curitĂ© est dĂ©montrĂ©e par les lois de la physique quantique. De premiers systĂšmes commerciaux de cette technologie sont aujourdâhui disponibles. Cette thĂšse sâintĂ©resse plus particuliĂšrement aux protocoles Ă variables continues, dont lâimplĂ©mentation pratique sâapproche des techniques modernes de transmissions numĂ©riques sur fibre optique. En exploitant ces techniques, on rĂ©alise un systĂšme expĂ©rimental de distribution quantique de clĂ©s Ă variables continues Ă haut dĂ©bit
Advanced signal processing techniques for continuous variable quantum key distribution over optical fiber
La distribution quantique de clĂ©s offre la possibilitĂ© dâune cryptographie dont la sĂ©curitĂ© est dĂ©montrĂ©e par les lois de la physique quantique. De premiers systĂšmes commerciaux de cette technologie sont aujourdâhui disponibles. Cette thĂšse sâintĂ©resse plus particuliĂšrement aux protocoles Ă variables continues, dont lâimplĂ©mentation pratique sâapproche des techniques modernes de transmissions numĂ©riques sur fibre optique. En exploitant ces techniques, on rĂ©alise un systĂšme expĂ©rimental de distribution quantique de clĂ©s Ă variables continues Ă haut dĂ©bit.Quantum key distribution offers the possibility of cryptography whose security is demonstrated by the laws of quantum physics. The first commercial systems of this technology are now available. This thesis focuses on continuous variable protocols, whose practical implementation is close to modern digital transmission techniques over optical fibers. By exploiting these techniques, we realize an experimental system for high speed continuous variable quantum key distribution
Du récepteur H1 aux facteurs de transcription (le cas mizolastine (petite histoire de l'histamine et des antihistaminiques))
MONTPELLIER-BU Pharmacie (341722105) / SudocSudocFranceF
Mesure des activités transcriptionnelles des glucocorticoïdes et caractérisation des effets anti-inflammatoires des antihistaminiques H1 et des antidépresseurs (implication pour le traitement de l'asthme)
MONTPELLIER-BU MĂ©decine UPM (341722108) / SudocPARIS-BIUP (751062107) / SudocMONTPELLIER-BU MĂ©decine (341722104) / SudocSudocFranceF
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