6,128 research outputs found
Two-dimensional hydrodynamic lattice-gas simulations of binary immiscible and ternary amphiphilic fluid flow through porous media
The behaviour of two dimensional binary and ternary amphiphilic fluids under
flow conditions is investigated using a hydrodynamic lattice gas model. After
the validation of the model in simple cases (Poiseuille flow, Darcy's law for
single component fluids), attention is focussed on the properties of binary
immiscible fluids in porous media. An extension of Darcy's law which explicitly
admits a viscous coupling between the fluids is verified, and evidence of
capillary effects are described. The influence of a third component, namely
surfactant, is studied in the same context. Invasion simulations have also been
performed. The effect of the applied force on the invasion process is reported.
As the forcing level increases, the invasion process becomes faster and the
residual oil saturation decreases. The introduction of surfactant in the
invading phase during imbibition produces new phenomena, including
emulsification and micellisation. At very low fluid forcing levels, this leads
to the production of a low-resistance gel, which then slows down the progress
of the invading fluid. At long times (beyond the water percolation threshold),
the concentration of remaining oil within the porous medium is lowered by the
action of surfactant, thus enhancing oil recovery. On the other hand, the
introduction of surfactant in the invading phase during drainage simulations
slows down the invasion process -- the invading fluid takes a more tortuous
path to invade the porous medium -- and reduces the oil recovery (the residual
oil saturation increases).Comment: 48 pages, 26 figures. Phys. Rev. E (in press
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Effects of contaminants of emerging concern on Megaselia scalaris (Lowe, Diptera: Phoridae) and its microbial community.
Drought, rising temperatures, and expanding human populations are increasing water demands. Many countries are extending potable water supplies by irrigating crops with wastewater. Unfortunately, wastewater contains biologically active, long-lived pharmaceuticals, even after treatment. Run-off from farms and wastewater treatment plant overflows contribute high concentrations of pharmaceuticals to the environment. This study assessed the effects of common pharmaceuticals on a cosmopolitan saprophagous insect, Megaselia scalaris (Diptera: Phoridae). Larvae were reared on artificial diets spiked with contaminants of emerging concern (CECs) at environmentally relevant concentrations. Female flies showed no oviposition preference for treated or untreated diets. Larvae exposed to caffeine in diets showed increased mortality, and larvae fed antibiotics and hormones showed signs of slowed development, especially in females. The normal sex ratio observed in M. scalaris from control diets was affected by exposure to caffeine and pharmaceutical mixture treatments. There was an overall effect of treatment on the flies' microbial communities; notably, caffeine fed insects displayed higher microbial variability. Eight bacterial families accounted for approximately 95% of the total microbes in diet and insects. Our results suggest that CECs at environmentally relevant concentrations can affect the biology and microbial communities of an insect of ecological and medical importance
Three dimensional hysdrodynamic lattice-gas simulations of binary immiscible and ternary amphiphilic flow through porous media
We report the results of a study of multiphase flow in porous media. A
Darcy's law for steady multiphase flow was investigated for both binary and
ternary amphiphilic flow. Linear flux-forcing relationships satisfying Onsager
reciprocity were shown to be a good approximation of the simulation data. The
dependence of the relative permeability coefficients on water saturation was
investigated and showed good qualitative agreement with experimental data.
Non-steady state invasion flows were investigated, with particular interest in
the asymptotic residual oil saturation. The addition of surfactant to the
invasive fluid was shown to significantly reduce the residual oil saturation.Comment: To appear in Phys. Rev.
Fisher's arrow of `time' in cosmological coherent phase space
Fisher's arrow of `time' in a cosmological phase space defined as in quantum
optics (i.e., whose points are coherent states) is introduced as follows.
Assuming that the phase space evolution of the universe starts from an initial
squeezed cosmological state towards a final thermal one, a Fokker-Planck
equation for the time-dependent, cosmological Q phase space probability
distribution can be written down. Next, using some recent results in the
literature, we derive an information arrow of time for the Fisher phase space
cosmological entropy based on the Q function. We also mention the application
of Fisher's arrow of time to stochastic inflation modelsComment: 10 pages, LaTex, Honorable Mention at GRF-199
Simulating Three-Dimensional Hydrodynamics on a Cellular-Automata Machine
We demonstrate how three-dimensional fluid flow simulations can be carried
out on the Cellular Automata Machine 8 (CAM-8), a special-purpose computer for
cellular-automata computations. The principal algorithmic innovation is the use
of a lattice-gas model with a 16-bit collision operator that is specially
adapted to the machine architecture. It is shown how the collision rules can be
optimized to obtain a low viscosity of the fluid. Predictions of the viscosity
based on a Boltzmann approximation agree well with measurements of the
viscosity made on CAM-8. Several test simulations of flows in simple geometries
-- channels, pipes, and a cubic array of spheres -- are carried out.
Measurements of average flux in these geometries compare well with theoretical
predictions.Comment: 19 pages, REVTeX and epsf macros require
Computer simulations of domain growth and phase separation in two-dimensional binary immiscible fluids using dissipative particle dynamics
We investigate the dynamical behavior of binary fluid systems in two
dimensions using dissipative particle dynamics. We find that following a
symmetric quench the domain size R(t) grows with time t according to two
distinct algebraic laws R(t) = t^n: at early times n = 1/2, while for later
times n = 2/3. Following an asymmetric quench we observe only n = 1/2, and if
momentum conservation is violated we see n = 1/3 at early times. Bubble
simulations confirm the existence of a finite surface tension and the validity
of Laplace's law. Our results are compared with similar simulations which have
been performed previously using molecular dynamics, lattice-gas and
lattice-Boltzmann automata, and Langevin dynamics. We conclude that dissipative
particle dynamics is a promising method for simulating fluid properties in such
systems.Comment: RevTeX; 22 pages, 5 low-resolution figures. For full-resolution
figures, connect to http://www.tcm.phy.cam.ac.uk/~ken21/tension/tension.htm
Interface Roughening in a Hydrodynamic Lattice-Gas Model with Surfactant
Using a hydrodynamic lattice-gas model, we study interface growth in a binary
fluid with various concentrations of surfactant. We find that the interface is
smoothed by small concentrations of surfactant, while microemulsion droplets
form for large surfactant concentrations. To assist in determining the
stability limits of the interface, we calculate the change in the roughness and
growth exponents and as a function of surfactant concentration
along the interface.Comment: 4 pages with 4 embedded ps figures. Requires psfig.tex. Will appear
in PRL 14 Oct 199
One in four die from acute infectious illness in an emergency department in Eastern Cape Province, South Africa
Background. Despite the breadth of data supporting evidence-based practice for sepsis care in high-resource settings, there are relatively few data to guide the management of sepsis in low-resource settings, particularly in areas where HIV and tuberculosis (TB) are prevalent. Furthermore, few studies had broadened sepsis parameters to include all patients with acute infectious illness or followed patients up after hospital discharge. Understanding the epidemiology and outcomes of acute infections in a local context is the critical first step to developing locally informed targeted management strategies.Objectives. To quantify and describe the incidence of and risk factors for mortality in a cohort of patients with undifferentiated acute infectious illnesses who presented to an emergency department (ED) in the Eastern Cape region of South Africa (SA).Methods. In this prospective cohort study, patients with suspected acute infectious illness were enrolled at a district casualty ward in Mthatha, SA, between 1 July and 1 September 2017. Demographic data, interventions, diagnostic studies and disposition were prospectively collected during the initial encounter and during the hospital stay. Follow-up was conducted both in hospital and via phone interviews 30Â days after the index visit.Results. A total of 301 patients presented to the ED with acute infectious illness during the study period, of whom 54.8% had complete 30-day follow-up. Of the study population, only 5.7% had a complete set of vital signs (heart rate, respiratory rate, blood pressure and temperature) documented. Of the cohort, 51.8% had HIV and 32.9% active or treated TB; 25.2% of patients died within 30 days. Accounting for medical history, diagnosis and ED interventions, risk of mortality was independently associated with age (odds ratio (OR) 1.03; 95% confidence interval (CI) 1.00 - 1.06), HIV-positive status (OR 4.10; 95% CI 1.44 - 11.67) and Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) score (OR 1.90; 95% CI 1.14 - 3.19) in an adjusted model. No ED interventions were protective for mortality, with intravenous fluid administration associated with increased 30-day mortality in this cohort (OR 3.65; 95% CI 1.38 - 9.62).Conclusions. Among adults with suspected acute infectious illness in Mthatha, SA, 30-day mortality was concerningly high. Mortality was highest in patients with concomitant HIV infection. In particular, vital sign assessment to identify possible sepsis in this cohort is crucial, as it affects mortality to a meaningful extent, yet is often unavailable. Future research is needed on the management of sepsis in low-resource settings, particularly in HIV-positive individuals
A consideration of the chi-square test of Hardy-Weinberg equilibrium in a non-multinomial situation
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65698/1/j.1469-1809.1975.tb00116.x.pd
Comment on 'The latency period of mesothelioma among a cohort of British asbestos workers (1978-2005)': methodological problems with case-only survival analysis.
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