3-dimensional electrode patterning within a microfluidic channel using metal ion implantation

The application of electrical fields within a microfluidic channel enables many forms of manipulation necessary for lab-on-a-chip devices. Patterning electrodes inside the microfluidic channel generally requires multi-step optical lithography. Here, we utilize an ion-implantation process to pattern 3D electrodes within a fluidic channel made of polydimethylsiloxane (PDMS). Electrode structuring within the channel is achieved by ion implantation at a 40° angle with a metal shadow mask. The advantages of three-dimensional structuring of electrodes within a fluidic channel over traditional planar electrode designs are discussed. Two possible applications are presented: asymmetric particles can be aligned in any of the three axial dimensions with electro-orientation; colloidal focusing and concentration within a fluidic channel can be achieved through dielectrophoresis. Demonstrations are shown with E. coli, a rod shaped bacteria, and indicate the potential that ion-implanted microfluidic channels have for manipulations in the context of lab-on-a-chip devices

Follow-up question handling in the IMIX and Ritel systems: A comparative study

One of the basic topics of question answering (QA) dialogue systems is how follow-up questions should be interpreted by a QA system. In this paper, we shall discuss our experience with the IMIX and Ritel systems, for both of which a follow-up question handling scheme has been developed, and corpora have been collected. These two systems are each other's opposites in many respects: IMIX is multimodal, non-factoid, black-box QA, while Ritel is speech, factoid, keyword-based QA. Nevertheless, we will show that they are quite comparable, and that it is fruitful to examine the similarities and differences. We shall look at how the systems are composed, and how real, non-expert, users interact with the systems. We shall also provide comparisons with systems from the literature where possible, and indicate where open issues lie and in what areas existing systems may be improved. We conclude that most systems have a common architecture with a set of common subtasks, in particular detecting follow-up questions and finding referents for them. We characterise these tasks using the typical techniques used for performing them, and data from our corpora. We also identify a special type of follow-up question, the discourse question, which is asked when the user is trying to understand an answer, and propose some basic methods for handling it

Sensitivity of a Bolometric Interferometer to the CMB power spectrum

Context. The search for B-mode polarization fluctuations in the Cosmic Microwave Background is one of the main challenges of modern cosmology. The expected level of the B-mode signal is very low and therefore requires the development of highly sensitive instruments with low systematic errors. An appealing possibility is bolometric interferometry. Aims. We compare in this article the sensitivity on the CMB angular power spectrum achieved with direct imaging, heterodyne and bolometric interferometry. Methods. Using a simple power spectrum estimator, we calculate its variance leading to the counterpart for bolometric interferometry of the well known Knox formula for direct imaging. Results. We find that bolometric interferometry is less sensitive than direct imaging. However, as expected, it is finally more sensitive than heterodyne interferometry due to the low noise of the bolometers. It therefore appears as an alternative to direct imagers with different and possibly lower systematic errors, mainly due to the absence of an optical setup in front of the horns.Comment: 5 pages, 3 figures. This last version matches the published version (Astronomy and Astrophysics 491 3 (2008) 923-927). Sensitivity of Heterodyne Interferometers modified by a factor of tw

L'inhibition de l'entartrage par les eaux géothermales du sud tunisien. Étude sur site

Une nappe d'eaux fossiles à grande profondeur (800 à 2 700 mètres) a été mise en exploitation dans le Sud-Tunisien pour alimenter une usine d'osmose inverse située à Gabès ayant une production de 15 000 m3 /jour, afin de lutter contre la désertification par irrigation et d'assurer le chauffage de serres pour la production de primeurs. La grande dureté (TH de l'ordre de 100 à 140 °F) de ces eaux géothermales a pour conséquence le colmatage rapide des conduites de distribution : 40 à 50 tonnes de tartre par forage, constitué essentiellement de carbonate de calcium, précipitent chaque année. Ce tartre est constitué d'aragonite comme le montrent la microscopie électronique à balayage et la diffraction des rayons X. Une technique électrochimique, la chronoélectrogravimétrie, permet d'étudier l'inhibition de l'entartrage par des composés de la famille des phosphates inorganiques, des phosphonates organiques et des polycarboxylates. La concentration efficace de chacun de ces inhibiteurs agissant par effet de seuil a été déterminée : elle est de l'ordre de 1,1 à 1,5 mg.l-1 pour l'eau du forage de EL HAMMA. Un essai sur le site de EL MANSOURA a été effectué en privilégiant un inhibiteur produit industriellement dans le Sud-Tunisien, le triphosphate de sodium. A la concentration de 1 mg.l-1 il évite l'entartrage du système de refroidissement de type cascade - piscines et des conduites de distribution.Deep fossil waters are used in Southern Tunisia (Gabès, Kébili, Tozeur) for the Gabès reverse osmosis plant, which delivers a flow rate of 15 000 m3 /day for irrigation and for heating greenhouses used for the production of early fruits and vegetables. Drilling depths vary between 800 and 2 700 meters. Water emerges under a pressure of ca. 20 bars and has a temperature between 50 and 73 °C. Mean flow rate is 7 800 m3 /day.Intake water at the Gabès plant has a salinity of 3.3 g.l-1 ; after reverse osmosis the salinity is less than 0.1 g.l-1. Water used for irrigation has to be cooled. Geothermal waters are characterized by high concentrations of calcium, magnesium, sulphate and chloride. Bicarbonate anions are present at limited concentrations (approx. 2.10-3 mol.l-1) that are, however, sufficient for the formation of large quantities of scale - 40 to 50 tons per year for each drilling. At the outlet of the drill hole, pressure decreases strongly, liberating carbon dioxide to the atmosphere. Water pH increases and the following equilibrium is displaced to the right, with scale precipitation : Ca2+ + 2HCO3-CO2 (g) + CaCO3(s) + H2OScale precipitation has two consequences :- the plugging of distribution pipes: a 85% reduction of the pipe has been observed, after four years, for an initial diameter of 15 cm; - water cooling installations such as cooling towers or pool systems are blocked by large quantities of scale, which have to be removed regularly. Scales have been analysed through inductively coupled plasma spectroscopy and thermogravimetry: calcium carbonate may represent, depending on the origin of the drilling water, 60 to 95% by weight of the solid. Iron oxides, silica, calcium phosphate and aluminum are present. Scanning electron microscopy and X-ray diffraction show that calcium carbonate precipitates in the form of aragonite. This is due to two reasons: the temperature at the drilling outlet is greater than 60 °C and the high magnesium concentration favours aragonite formation. Scale inhibition is possible through the use of certain chemicals such as phosphates, organic phosphonates and polycarboxylates.Chronoelectrogravimetry was used as the experimental method to determine the inhibitor concentration able to suppress scale precipitation. Dissolved oxygen is electrochemically reduced on a gold electrode; hydroxide anions are produced in the vicinity of the electrode and calcium carbonate precipitates according to:4Ca2+ + 4HCO3- + O2 + 4e -> 4CaCO3(s) + 2H2OThe gold electrode is deposited on the quartz disk of a recording microbalance. The electrode is polarized at - 1 V/SCE with a three-electrode potentiostatic device and the weight of CaCO3 deposited is recorded versus time.Four inhibitors have been studied :- PERMATREAT 191, which is the sodium salt of aminotris(methylenephosphonic) acid N(CH2COONa)3; - a proprietary organic phosphonate with high resistance to chlorine oxidation (DEQUEST 6004) ; - phosphonobutanetricarboxylic acid (DEQUEST 7000, BAYHIBIT-AM) ; - a copolymer of acrylic acid and acrylamidopropanesulfonic acid (FERROPHOS 5248). Breakthrough effects are obtained in the case of EL HAMMA water for the following concentrations: PERMATREAT 191: 1.1 mg.l-1 ; DEQUEST 6004: 1.5 mg.l-1 ; DEQUEST 7000: 1.3 mg.l-1 ; FERROPHOS 5248: 1.4 mg.l-1. These concentrations are low and, as a consequence, these inhibitors can be used for antiscale action even with high water flow rates.A field experiment was carried out on the EL MANSOURA drilling where water is cooled in three pools (input water: 5 184 m3 /day, temperature: 60 °C). For economical reasons the chosen inhibitor was sodium triphosphate Na5 P3 O10, which is produced industrially in Southern Tunisia. By chronoelectrogravimetry it has been shown that, with EL MANSOURA water, a breakthrough effect is obtained with a sodium triphosphate concentration of 0.75 mg.l-1.A dosing pump was used to inject sodium triphosphate in such a way that the inhibitor concentration would be 1 mg.l-1 in one of three pools, the two others not being treated. After four months a scale deposit of 23 cm was obtained in the untreated pools and the pipe diameter was reduced by 39%. In the treated pool scale deposit was not observed and the pipe diameter remained unchanged. In the untreated basins, examination of scale with electron scanning microscopy revealed that it was aragonite; in the treated basin, the precipitate was amorphous and an X-ray diffraction pattern with no characteristic bands was obtained.Some algal development was observed in the pool due to phosphate addition but this development was not a nuisance after the four month period. However, it could be suppressed by the use of an organic phosphonate or polycarboxylate as scale inhibitor

A simple modeling approach to study the regional impact of a Mediterranean forest isoprene emission on anthropogenic plumes

Research during the past decades has outlined the importance of biogenic isoprene emission in tropospheric chemistry and regional ozone photo-oxidant pollution. The first part of this article focuses on the development and validation of a simple biogenic emission scheme designed for regional studies. Experimental data sets relative to Boreal, Tropical, Temperate and Mediterranean ecosystems are used to estimate the robustness of the scheme at the canopy scale, and over contrasted climatic and ecological conditions. A good agreement is generally found when comparing field measurements and simulated emission fluxes, encouraging us to consider the model suitable for regional application. Limitations of the scheme are nevertheless outlined as well as further on-going improvements. In the second part of the article, the emission scheme is used on line in the broader context of a meso-scale atmospheric chemistry model. Dynamically idealized simulations are carried out to study the chemical interactions of pollutant plumes with realistic isoprene emissions coming from a Mediterranean oak forest. Two types of anthropogenic sources, respectively representative of the Marseille (urban) and Martigues (industrial) French Mediterranean sites, and both characterized by different VOC/NOx are considered. For the Marseille scenario, the impact of biogenic emission on ozone production is larger when the forest is situated in a sub-urban configuration (i.e.&nbsp;downwind distance TOWN-FOREST <30km, considering an advection velocity of 4.2 m.s^-1). In this case the enhancement of ozone production due to isoprene can reach +37% in term of maximum surface concentrations and +11% in term of total ozone production. The impact of biogenic emission decreases quite rapidly when the TOWN-FOREST distance increases. For the Martigues scenario, the biogenic impact on the plume is significant up to TOWN-FOREST distance of 90km where the ozone maximum surface concentration enhancement can still reach +30%. For both cases, the importance of the VOC/NO_x ratio in the anthropogenic plume and its evolution when interacting with the forest emission are outlined. In complement to real case studies, this idealized approach can be particularly useful for process and sensitivity studies and constitutes a valuable tool to build regional ozone control strategies

Le Hamburger surgelé conditionné. Préparation-contrôle

Lecompte M., Rosset Roland. Le hamburger surgelé conditionné. Préparation - contrôle. In: Bulletin de l'Académie Vétérinaire de France tome 118 n°7, 1965. pp. 291-296

Technique nouvelle d’inspection Bactériologique des viandes : principes directeurs, protocole de recherche

Pantaléon Jean, Rosset Roland. Technique nouvelle d’inspection Bactériologique des viandes : principes directeurs, protocole de recherche. In: Bulletin de l'Académie Vétérinaire de France tome 115 n°9, 1962. pp. 365-370

Tuning parameters of metal ion implantation within a microfluidic channel

Applying electrical fields is a simple and versatile method to manipulate and reconfigure optofluidic devices. Several methods to apply electric fields using electrodes on polymers or in the context of lab-on-a-chip devices exist. In this paper, we utilize an ion-implanted process to pattern electrodes within a fluidic channel made of polydimethylsiloxane (PDMS). Electrode structuring within the channel is achieved by ion implantation at a 40° angle with a metal shadow mask. In previous work using the ion-implantation process, we demonstrated two possible applications in the context of lab-on-a-chip applications. Asymmetric particles were aligned through electro-orientation. Colloidal focusing and concentration was possible with negative dielectrophoresis. In this paper, we discuss the different electrode structures that are possible by changing the channel dimensions. A second parameter of ion implantation dosage prevents the shorting of electrodes on the side wall or top wall of the fluidic channel to the bottom. This allows for floating electrodes on the side wall or top wall. These type of electrodes help prevent electrolysis as the liquid is not in direct contact with the voltage source. Possible applications of the different electrode structures that are possible are discussed