Performance of commercial corn hybrids in Illinois, 1975, with 1973 and 1974 listings / 1118

Chiefly tables

Pre-Revolutionary Popular Constitutionalism and Larry Kramer\u27s \u3cem\u3eThe People Themselves\u3c/em\u3e

Larry Kramer\u27s depiction of pre-Revolutionary constitutionalism rests on two dichotomies that are valuable yet exclude middle positions. First, he distinguishes between fundamental law and ordinary law. Second, he argues that pre-Revolutionary judges could play one of two roles—since they were not supreme constitutional interpreters (the first of these roles), they must have possessed no special authority to determine constitutional meanings (the second, and remaining, possibility). Both of these dichotomies obscure middle positions that capture important aspects of the pre-Revolutionary constitutional tradition. My comments briefly identify these middle positions and suggest what is at stake in recovering them

Pre-Revolutionary Popular Constitutionalism and Larry Kramer\u27s \u3cem\u3eThe People Themselves\u3c/em\u3e

Larry Kramer\u27s depiction of pre-Revolutionary constitutionalism rests on two dichotomies that are valuable yet exclude middle positions. First, he distinguishes between fundamental law and ordinary law. Second, he argues that pre-Revolutionary judges could play one of two roles—since they were not supreme constitutional interpreters (the first of these roles), they must have possessed no special authority to determine constitutional meanings (the second, and remaining, possibility). Both of these dichotomies obscure middle positions that capture important aspects of the pre-Revolutionary constitutional tradition. My comments briefly identify these middle positions and suggest what is at stake in recovering them

Mifepristone reduces insulin resistance in patient volunteers with adrenal incidentalomas that secrete low levels of cortisol : a pilot study

Background: Incidental adrenal masses are commonly detected during imaging for other pathologies. 10% of the elderly population has an ‘adrenal incidentaloma’, up to 20% of these show low-grade autonomous cortisol secretion and 60% of patients with autonomous cortisol secretion have insulin resistance. Cortisol excess is known to cause insulin resistance, an independent cardiovascular risk marker, however in patients with adrenal incidentalomas it is unknown whether their insulin resistance is secondary to the excess cortisol and therefore potentially reversible. In a proof of concept study we examined the short-term effects of glucocorticoid receptor (GR) antagonism in patients with an adrenal incidentaloma to determine whether their insulin resistance was reversible. Methodology/Principal Findings: In a prospective open-label pilot study, six individuals with adrenal incidentalomas and autonomous cortisol secretion were treated with mifepristone (a GR antagonist) 200 mg twice daily and studied for 4 weeks on a Clinical Research Facility. Insulin resistance at four weeks was assessed by insulin resistance indices, lnHOMA-IR and lnMatsuda, and AUC insulin during a 2-hour glucose tolerance test. Biochemical evidence of GR blockade was shown in all individuals and across the group there was a significant reduction in insulin resistance: lnHOMA-IR (1.0vs0.6; p = 0.03), lnHOMA-%beta (4.8vs4.3; p = 0.03) and lnMatsuda (1.2vs1.6; p = 0.03). Five out of six individuals showed a reduction in insulin AUC .7237 pmol/l.min, and in two patients this showed a clinically significant cardiovascular benefit (as defined by the Helsinki heart study). Conclusions: Short-term GR antagonism is sufficient to reduce insulin resistance in some individuals with adrenal incidentalomas and mild cortisol excess. Further assessment is required to assess if the responses may be used to stratify therapy as adrenal incidentalomas may be a common remediable cause of increased cardiovascular risk

Supernova enrichment and dynamical histories of solar-type stars in clusters

We use N-body simulations of star cluster evolution to explore the hypothesis that short-lived radioactive isotopes found in meteorites, such as 26-Al, were delivered to the Sun's protoplanetary disc from a supernova at the epoch of Solar System formation. We cover a range of star cluster formation parameter space and model both clusters with primordial substructure, and those with smooth profiles. We also adopt different initial virial ratios - from cool, collapsing clusters to warm, expanding associations. In each cluster we place the same stellar population; the clusters each have 2100 stars, and contain one massive 25M_Sun star which is expected to explode as a supernova at about 6.6Myr. We determine the number of Solar (G)-type stars that are within 0.1 - 0.3pc of the 25M_Sun star at the time of the supernova, which is the distance required to enrich the protoplanetary disc with the 26-Al abundances found in meteorites. We then determine how many of these G-dwarfs are unperturbed `singletons'; stars which are never in close binaries, nor suffer sub-100au encounters, and which also do not suffer strong dynamical perturbations. The evolution of a suite of twenty initially identical clusters is highly stochastic, with the supernova enriching over 10 G-dwarfs in some clusters, and none at all in others. Typically only ~25 per cent of clusters contain enriched, unperturbed singletons, and usually only 1 - 2 per cluster (from a total of 96 G-dwarfs in each cluster). The initial conditions for star formation do not strongly affect the results, although a higher fraction of supervirial (expanding) clusters would contain enriched G-dwarfs if the supernova occurred earlier than 6.6Myr. If we sum together simulations with identical initial conditions, then ~1 per cent of all G-dwarfs in our simulations are enriched, unperturbed singletons.Comment: 14 pages, 5 figures, accepted for publication in MNRA

Instantaneous Pair Theory for High-Frequency Vibrational Energy Relaxation in Fluids

Notwithstanding the long and distinguished history of studies of vibrational energy relaxation, exactly how it is that high frequency vibrations manage to relax in a liquid remains somewhat of a mystery. Both experimental and theoretical approaches seem to say that there is a natural frequency range associated with intermolecular motions in liquids, typically spanning no more than a few hundred cm^{-1}. Landau-Teller-like theories explain how a solvent can absorb any vibrational energy within this "band", but how is it that molecules can rid themselves of superfluous vibrational energies significantly in excess of these values? We develop a theory for such processes based on the idea that the crucial liquid motions are those that most rapidly modulate the force on the vibrating coordinate -- and that by far the most important of these motions are those involving what we have called the mutual nearest neighbors of the vibrating solute. Specifically, we suggest that whenever there is a single solvent molecule sufficiently close to the solute that the solvent and solute are each other's nearest neighbors, then the instantaneous scattering dynamics of the solute-solvent pair alone suffices to explain the high frequency relaxation. The many-body features of the liquid only appear in the guise of a purely equilibrium problem, that of finding the likelihood of particularly effective solvent arrangements around the solute. These results are tested numerically on model diatomic solutes dissolved in atomic fluids (including the experimentally and theoretically interesting case of I_2 in Xe). The instantaneous pair theory leads to results in quantitative agreement with those obtained from far more laborious exact molecular dynamics simulations.Comment: 55 pages, 6 figures Scheduled to appear in J. Chem. Phys., Jan, 199