645 research outputs found
Isochromosome 13 in a patient with childhood-onset schizophrenia, ADHD, and motor tic disorder
A Three three-brane Universe:New Phenomenology for the New Millennium?
We consider an extension of the Randall-Sundrum model with three parallel
3-branes in a 5-dimensional spacetime. This new construction, apart from
providing a solution to the Planck hierarchy problem, has the advantage that
the SM fields are confined on a positive tension brane. The study of the
phenomenology of this model reveals an anomalous first KK state which is
generally much lighter than the remaining tower and also much more strongly
coupled to matter. Bounds on the parameter space of the model can be placed by
comparison of specific processes with the SM background as well as by the
latest Cavendish experiments. The model suggests a further exotic possibility
if one drops the requirement of solving the hierarchy problem. In this case
gravity may result from the exchange of the ordinary graviton plus an
ultralight KK state and modifications of gravity may occur at both small and
extremely large scales.Comment: 17 pages, 5 Postscript figures, uses axodraw.sty, corrected some
typo
LHC Searches for Non-Chiral Weakly Charged Multiplets
Because the TeV-scale to be probed at the Large Hadron Collider should shed
light on the naturalness, hierarchy, and dark matter problems, most searches to
date have focused on new physics signatures motivated by possible solutions to
these puzzles. In this paper, we consider some candidates for new states that
although not well-motivated from this standpoint are obvious possibilities that
current search strategies would miss. In particular we consider vector
representations of fermions in multiplets of with a lightest neutral
state. Standard search strategies would fail to find such particles because of
the expected small one-loop-level splitting between charged and neutral states.Comment: 16 pages, 9 figure
The stransverse mass, MT2, in special cases
This document describes some special cases in which the stransverse mass,
MT2, may be calculated by non-iterative algorithms. The most notable special
case is that in which the visible particles and the hypothesised invisible
particles are massless -- a situation relevant to its current usage in the
Large Hadron Collider as a discovery variable, and a situation for which no
analytic answer was previously known. We also derive an expression for MT2 in
another set of new (though arguably less interesting) special cases in which
the missing transverse momentum must point parallel or anti parallel to the
visible momentum sum. In addition, we find new derivations for already known
MT2 solutions in a manner that maintains manifest contralinear boost invariance
throughout, providing new insights into old results. Along the way, we stumble
across some unexpected results and make conjectures relating to geometric forms
of M_eff and H_T and their relationship to MT2.Comment: 11 pages, no figures. v2 corrects minor typos. v3 corrects an
incorrect statement in footnote 8 and inserts a missing term in eq (3.9). v4
and v5 correct minor typos spotted by reader
Multi-Localization in Multi-Brane Worlds
We study bulk fields in various multi-brane models with localized gravity. In
the case of spin 0, 1/2 and 3/2 fields, the non-trivial background geometry
itself can induce (multi-) localization of the zero modes along the extra
dimension. The addition of appropriate mass terms controls the strength or/and
the position of this localization and can induce (multi-) localization of spin
1 fields as well. We show that multi-brane models may also give rise to
anomalously light KK modes which are also localized. The possibility of
multi-localization in the context of supersymmetric brane world models in AdS_5
spacetime is also discussed.Comment: 34 pages, 5 figure
Vaccination with DNA plasmids expressing Gn coupled to C3d or alphavirus replicons expressing Gn protects mice against rift valley fever virus
Background: Rift Valley fever (RVF) is an arthropod-borne viral zoonosis. Rift Valley fever virus (RVFV) is an important biological threat with the potential to spread to new susceptible areas. In addition, it is a potential biowarfare agent. Methodology/Principal Findings: We developed two potential vaccines, DNA plasmids and alphavirus replicons, expressing the Gn glycoprotein of RVFV alone or fused to three copies of complement protein, C3d. Each vaccine was administered to mice in an all DNA, all replicon, or a DNA prime/replicon boost strategy and both the humoral and cellular responses were assessed. DNA plasmids expressing Gn-C3d and alphavirus replicons expressing Gn elicited high titer neutralizing antibodies that were similar to titers elicited by the live-attenuated MP12 virus. Mice vaccinated with an inactivated form of MP12 did elicit high titer antibodies, but these antibodies were unable to neutralize RVFV infection. However, only vaccine strategies incorporating alphavirus replicons elicited cellular responses to Gn. Both vaccines strategies completely prevented weight loss and morbidity and protected against lethal RVFV challenge. Passive transfer of antisera from vaccinated mice into naïve mice showed that both DNA plasmids expressing Gn-C3d and alphavirus replicons expressing Gn elicited antibodies that protected mice as well as sera from mice immunized with MP12. Conclusion/Significance: These results show that both DNA plasmids expressing Gn-C3d and alphavirus replicons expressing Gn administered alone or in a DNA prime/replicon boost strategy are effective RVFV vaccines. These vaccine strategies provide safer alternatives to using live-attenuated RVFV vaccines for human use. © 2010 Bhardwaj et al
Flavor Symmetries and The Problem of Squark Degeneracy
If supersymmetry exists at low energies, it is necessary to understand why
the squark spectrum exhibits sufficient degeneracy to suppress flavor changing
neutral currents. In this note, we point out that gauged horizontal symmetries
can yield realistic quark mass matrices, while at the same time giving just
barely enough squark degeneracy to account for neutral -meson phenomenology.
This approach suggests likely patterns for squark masses, and indicates that
there could be significant supersymmetric contributions to and
mixing and CP violation in the and systems.Comment: preprint SCIPP 93/04,SLAC-PUB-6147, 14 pages, 4 tables included; uses
macro package TABLES.TEX and phyzzx forma
Supersymmetry and primordial black hole abundance constraints
We study the consequences of supersymmetry for primordial black hole (PBH)
abundance constraints. PBHs with mass less than about 10^{11}g will emit
supersymmetric particles when they evaporate. In most models of supersymmetry
the lightest of these particles, the lightest supersymmetric particle (LSP), is
stable and will hence survive to the present day. We calculate the limit on the
initial abundance of PBHs from the requirement that the present day LSP density
is less than the critical density. We apply this limit, along with those
previously obtained from the effects of PBH evaporation on nucleosynthesis and
the present day density of PBHs, to PBHs formed from the collpase of
inflationary density perturbations, in the context of supersymmetric inflation
models. If the reheat temperature after inflation is low, so as to avoid the
overproduction of gravitinos and moduli, then the lightest PBHs which are
produced in significant numbers will be evaporating around the present day and
there are therefore no constraints from the effects of the evaporation products
on nucleosynthesis or from the production of LSPs. We then examine models with
a high reheat temperature and a subsequent period of thermal inflation. In
these models avoiding the overproduction of LSPs limits the abundance of low
mass PBHs which were previously unconstrained. Throughout we incorporate the
production, at fixed time, of PBHs with a range of masses, which occurs when
critical collapse is taken into account.Comment: 8 pages RevTeX file with 3 figures incorporated (uses RevTeX and
epsf). Version to appear in Phys. Rev. D: minor change to calculation and
added discussio
Single-Scale Natural SUSY
We consider the prospects for natural SUSY models consistent with current
data. Recent constraints make the standard paradigm unnatural so we consider
what could be a minimal extension consistent with what we now know. The most
promising such scenarios extend the MSSM with new tree-level Higgs interactions
that can lift its mass to at least 125 GeV and also allow for flavor-dependent
soft terms so that the third generation squarks are lighter than current bounds
on the first and second generation squarks. We argue that a common feature of
almost all such models is the need for a new scale near 10 TeV, such as a scale
of Higgsing or confinement of a new gauge group. We consider the question
whether such a model can naturally derive from a single mass scale associated
with supersymmetry breaking. Most such models simply postulate new scales,
leaving their proximity to the scale of MSSM soft terms a mystery. This
coincidence problem may be thought of as a mild tuning, analogous to the usual
mu problem. We find that a single mass scale origin is challenging, but suggest
that a more natural origin for such a new dynamical scale is the gravitino
mass, m_{3/2}, in theories where the MSSM soft terms are a loop factor below
m_{3/2}. As an example, we build a variant of the NMSSM where the singlet S is
composite, and the strong dynamics leading to compositeness is triggered by
masses of order m_{3/2} for some fields. Our focus is the Higgs sector, but our
model is compatible with a light stop (with the other generation squarks heavy,
or with R-parity violation or another mechanism to hide them from current
searches). All the interesting low-energy mass scales, including linear terms
for S playing a key role in EWSB, arise dynamically from the single scale
m_{3/2}. However, numerical coefficients from RG effects and wavefunction
factors in an extra dimension complicate the otherwise simple story.Comment: 32 pages, 3 figures; version accepted by JHE
High-Input Management Systems Effect on Soybean Seed Yield, Yield Components, and Economic Break-Even Probabilities
Elevated soybean [Glycine max (L.) Merr.] prices have spurred interest in maximizing soybean seed yield and has led growers to increase the number of inputs in their production systems. However, little information exists about the effects of high-input management on soybean yield and profitability. The purpose of this study was to investigate the effects of individual inputs, as well as combinations of inputs marketed to protect or increase soybean seed yield, yield components, and economic break-even probabilities. Studies were established in nine states and three soybean growing regions (North, Central, and South) between 2012 and 2014. In each site-year both individual inputs and combination high-input (SOYA) management systems were tested. When averaged between 2012 and 2014, regional results showed no seed yield responses in the South region, but multiple inputs affected seed yield in the North region. In general, the combination SOYA inputs resulted in the greatest yield increases (up to 12%) compared to standard management, but Bayesian economic analysis indicated SOYA had low break-even probabilities. Foliar insecticide had the greatest break-even probabilities across all environments, although insect pressure was generally low across all site-years. Soybean producers in North region are likely to realize a greater response from increased inputs, but producers across all regions should carefully evaluate adding inputs to their soybean management systems and ensure that they continue to follow the principles of integrated pest management
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