12 research outputs found

    Electrolysers Powered with Solar Energy

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    The vast fossil fuel consumption and decreasing oil reserves and natural resources, enforce much more need of finding decision for renewable energies and development of constructions for using the so called green resources. One solution of this problem is combination ofalready established solar based sources and brown gas cell construction. Brown gas cell production is based on electrolysis of pure water and as a result generating a real gas fuel. This production can find large utility in different usages

    High-fidelity superadiabatic population transfer of a two-level system with a linearly chirped Gaussian pulse

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    We investigate high-fidelity superadiabatic quantum driving in a chirped Gaussian two-level model with a Gaussian temporal envelope and a linear detuning. We show that the nonadiabatic losses can be canceled to any desired order by constructing and adjusting an auxiliary Hamiltonian (counter-diabatic field) and a symmetry in the fidelity arises on the counter-diabatic field ratio. A high-fidelity, robust, and accelerated (in a shorter time) transitionless superadiabatic population transfer is achieved that ensures a perfect following of the instantaneous adiabatic ground state even in the nonadiabatic regime. The features make the superadiabatic protocol a potentially important tool for quantum information. Copyright (C) EPLA, 2016National Basic Research Program of China (973 Program) [2013CBA01502, 2013CB834100]; National Natural Science Foundation of China [11665020, 11547046, 11374040, 11475027, 11575027, 11274051]; China Postdoctoral Science Foundation [2015M580068]; Natural Science Foundation of Gansu Province, China [1606RJZA081]SCI(E)ARTICLE611

    III. ABTEILUNG. BIBLIOGRAPHISCHE NOTIZEN UND MITTEILUNGEN

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    Edoxaban versus warfarin in patients with atrial fibrillation

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    Contains fulltext : 125374.pdf (publisher's version ) (Open Access)BACKGROUND: Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. METHODS: We conducted a randomized, double-blind, double-dummy trial comparing two once-daily regimens of edoxaban with warfarin in 21,105 patients with moderate-to-high-risk atrial fibrillation (median follow-up, 2.8 years). The primary efficacy end point was stroke or systemic embolism. Each edoxaban regimen was tested for noninferiority to warfarin during the treatment period. The principal safety end point was major bleeding. RESULTS: The annualized rate of the primary end point during treatment was 1.50% with warfarin (median time in the therapeutic range, 68.4%), as compared with 1.18% with high-dose edoxaban (hazard ratio, 0.79; 97.5% confidence interval [CI], 0.63 to 0.99; P<0.001 for noninferiority) and 1.61% with low-dose edoxaban (hazard ratio, 1.07; 97.5% CI, 0.87 to 1.31; P=0.005 for noninferiority). In the intention-to-treat analysis, there was a trend favoring high-dose edoxaban versus warfarin (hazard ratio, 0.87; 97.5% CI, 0.73 to 1.04; P=0.08) and an unfavorable trend with low-dose edoxaban versus warfarin (hazard ratio, 1.13; 97.5% CI, 0.96 to 1.34; P=0.10). The annualized rate of major bleeding was 3.43% with warfarin versus 2.75% with high-dose edoxaban (hazard ratio, 0.80; 95% CI, 0.71 to 0.91; P<0.001) and 1.61% with low-dose edoxaban (hazard ratio, 0.47; 95% CI, 0.41 to 0.55; P<0.001). The corresponding annualized rates of death from cardiovascular causes were 3.17% versus 2.74% (hazard ratio, 0.86; 95% CI, 0.77 to 0.97; P=0.01), and 2.71% (hazard ratio, 0.85; 95% CI, 0.76 to 0.96; P=0.008), and the corresponding rates of the key secondary end point (a composite of stroke, systemic embolism, or death from cardiovascular causes) were 4.43% versus 3.85% (hazard ratio, 0.87; 95% CI, 0.78 to 0.96; P=0.005), and 4.23% (hazard ratio, 0.95; 95% CI, 0.86 to 1.05; P=0.32). CONCLUSIONS: Both once-daily regimens of edoxaban were noninferior to warfarin with respect to the prevention of stroke or systemic embolism and were associated with significantly lower rates of bleeding and death from cardiovascular causes. (Funded by Daiichi Sankyo Pharma Development; ENGAGE AF-TIMI 48 ClinicalTrials.gov number, NCT00781391.)

    Coherent manipulations of atoms using laser light

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