Does having siblings affect caretaking responses to infants?

Infant facial cues affect a variety of caretaking-related responses in adults. These effects have primarily been explored as they relate to parental care, however infants receive care from others who are not their parents and it would be important for any caregiver, regardless of parental status, to respond to infant cues effectively. Because siblings often fulfill a caregiver role in the home, this study investigated whether having siblings, younger siblings in particular, influences the way in which adults respond to infant cues. Contrary to my predictions, the findings in this study indicate that having siblings does not influence how rewarding infant cuteness is nor how sensitive participants are to infant cuteness. Additional analyses exploring the potential impact of experience with younger siblings also failed to show that responses to infant cues were sensitive to this type of alloparental care. Future research should consider investigating if the age difference between siblings affects responses to infant cues

CONCENTRATION AND COMPOSITION OF NANOPARTICLES AND COLLOIDAL PARTICLES IN A MINE-WASTE CONTAMINATED RIVER

Metals and metalloids (metal(loid)s) in aquatic ecosystems are often described through measures of their concentrations in whole and filtered waters. The filtered fraction is operationally defined as “dissolved,” and assumed to be primarily composed of free metal(loid) ions or of ions bound by low molecular weight organic matter. This definition ignores that the dissolved fraction also likely contains colloidal particles (1 to 1000 nm) that can pass through commonly used filters. This colloidal fraction can also be preferentially removed from the water column by algae and other aquatic organisms compared to free metal(loid) ions and organic bound metal(loid)s. Though they may be important in describing the bioavailability and toxicity of contaminants, the abundance and composition of colloidal particles is not well described. To better understand the abundance and elemental composition of colloidal particles in aquatic ecosystems, we used single particle inductively coupled plasma time-of-flight mass spectrometry (spICP-TOFMS) to simultaneously characterize and quantify a range of elements in individual colloidal particles. We collected samples from eight mainstem sites and two tributaries to the Clark Fork River, Montana, which has a legacy of metal(loid) contamination in its sediments and surface waters from past mining and ore processing. Colloidal particles were abundant in all samples, with 144 different particle types detected. The most common particle types contained Fe and Mn. Single-element particles were more abundant than multi-element particles, however our estimate of multi-element particles is likely conservative due to the small size of the single-element particles (median 83 nm) which may limit detection for minor components. Multi-element colloidal particles mostly consisted of Fe and Mn in combination with other metal(loid)s, indicating Fe and Mn may serve as vectors for more toxic metal(loid)s. Our data suggest biogeochemistry drove the presence of the abundant Fe and Mn containing particles, which contrast with the Al and Si rich sediment. The small size of the colloidal metal(loid) particles suggests that that contaminant exposure to organisms occurs as complex assemblages of colloidal particles. Loads of elements in colloidal particles increased for many elements from upstream to downstream, though the exact mechanisms behind this increase are unknown. The abundance of colloidal particles in this study suggests that they may be important to the fate and transport of metal(loid) contaminants, and that they may be important to consider when examining exposure, accumulation, and toxicity of metal(loid) contaminants in aquatic ecosystems

Read in or check out: A four-year analysis of circulation and in-house use of print books

As libraries offer more multi-dimensional study areas and online resources, it is important to understand how print books are being used. The reported decline in print book circulation has largely been based on books checked out of the library without recording in-house use (books used in the library but not checked out). Including in-house use gives a more accurate representation of book circulation, helping to demonstrate the value of the physical library and print collections, and informing collection development. To better understand how our print collections are being used, we analyze holdings, checkout data, and in-house use data by subject, as well as circulation in regard to patron group, library gate count and student enrollment. Our findings show declining use of all print collections with the steepest decline in reference books. The majority of books used in house were not checked out, affirming the need to include in-house use data to provide an accurate picture of print book use and inform collection development. We use our findings to inform the redesign of our reference collection and suggest ways to integrate print and digital formats and promote the value of books and reading

Teaching Dog Safety Skills to Children via Remote Technology

Behavior analysts have been effective in teaching various safety skills (e.g., Dancho et al., 2008; Himle et al., 2004; Miltenberger et al., 2009); however, few studies have evaluated dog safety skills. Over 4.5 million people are bitten by dogs each year and more than half are children (American Humane, 2019). Additionally, children often engage in behaviors that may increase the likelihood of dog bites and injuries (Patronek et al., 2013). Therefore, it is important to develop effective dog safety skills trainings. In Study 1, we conducted a survey to identify the prevalence of dog bites, common behavior of children around known and unknown dogs, and the importance of teaching dog safety skills to children as reported by their caregivers. Results of the survey suggest that children are more likely to sustain bites and injuries from known dogs, engage in behaviors that increase the likelihood of bites and injuries, and caregivers find dog safety skills important. In Study 2, we evaluated the effects of remote behavioral skills training in teaching three children to engage in safe behavior in the presence of unknown, off-leash dog videos. Remote behavioral skills training was effective for all three participants, and generalization occurred for two of the three participants to novel videos of unknown, off-leash dog videos

Bi-Directional Learning: Identifying Contaminants on the Yurok Indian Reservation.

The Yurok Tribe partnered with the University of California Davis (UC Davis) Superfund Research Program to identify and address contaminants in the Klamath watershed that may be impairing human and ecosystem health. We draw on a community-based participatory research approach that begins with community concerns, includes shared duties across the research process, and collaborative interpretation of results. A primary challenge facing University and Tribal researchers on this project is the complexity of the relationship(s) between the identity and concentrations of contaminants and the diversity of illnesses plaguing community members. The framework of bi-directional learning includes Yurok-led river sampling, Yurok traditional ecological knowledge, University lab analysis, and collaborative interpretation of results. Yurok staff and community members share their unique exposure pathways, their knowledge of the landscape, their past scientific studies, and the history of landscape management, and University researchers use both specific and broad scope chemical screening techniques to attempt to identify contaminants and their sources. Both university and tribal knowledge are crucial to understanding the relationship between human and environmental health. This paper examines University and Tribal researchers' shared learning, progress, and challenges at the end of the second year of a five-year Superfund Research Program (SRP) grant to identify and remediate toxins in the lower Klamath River watershed. Our water quality research is framed within a larger question of how to best build university-Tribal collaboration to address contamination and associated human health impacts

Engineering Education Guilds: Understanding Their Vision for Innovation

Engineering education guilds, such as the Consortium to Promote Reflection in Engineering Education (CPREE) and the Kern Entrepreneurial Engineering Network (KEEN), seek to work at the forefront of educational innovation by creating networks of instructor change agents who design and implement a particular innovation in their own context to further the professional formation of engineers (PFE). While many of the innovations facilitated by CPREE and KEEN have been published extensively, it is unclear how successful the propagation of reflection and entrepreneurial mindset has been in the engineering education community. The major aim of this project is to characterize these two engineering education guilds with respect to their dissemination/propagation plans and, in the future, quantify the propagation of the innovations championed by CPREE and KEEN. The research questions we seek to answer in this paper are: (1) What are the planned dissemination/propagation approaches of well-established engineering education guilds? and (2) To what extent do their characteristics align with the Designing for Sustained Adoption Assessment Instrument (DSAAI)? The DSAAI was developed in 2016 to provide education developers, grant writing consultants, and funding agencies with a tool for assessing the propagation plans of researchers developing educational change strategies. To answer these questions, we conducted semi-structured interviews with the leaders of CPREE and KEEN. The transcriptions of the interviews will be used to create within-case reports for each guild. The within-case reports will consist of a rich description of the pedagogical innovation as well as the history of the guild and its goals. Using the DSAAI, we will qualitatively code the techniques that each guild is using to facilitate widespread adoption as well as the extent to which they are following a dissemination or propagation paradigm. Lastly, thematic analysis will be used to capture emerging themes that arise from the interviews

Living Mercy: Reflecting on the Vocation and Values of Salve Regina University

With this collection of essays, we honor the vocation and spirit of mercy that has enlivened and guided Salve Regina University for the last 75 years. Inspired by the accomplishments of the past and looking forward to the call of the future, these essays provide a starting point for University-wide conversations to support Salve Regina in discerning how it will move into the increasingly complex challenges of the future. Salve\u27s tradition of mercy is rooted in the example of Catherine McAuley, who founded the Sisters of Mercy in 19th-century Dublin, Ireland. It is a model of faith expressed through action and maintains that each person is called to and capable of contributing to the common good by responding to the needs of the day, to respond to the suffering and injustice of each era.Attending to this spirit of mercy that continues to guide our University, this project considers how the six core values of Salve’s Strategic Compass – purpose-driven education, respect and dignity for all, mercy community, integrity, faith and spirituality, and compassionate service and solidarity – relate to our shared mercy, Catholic heritage, and the mercy vocational paradigm. Exploring how to re-root and re-frame these values, we approached the project as a vocationally oriented narrative. This type of narrative focuses on the call and vocation, as well as the patterns of meaning that shape the unique identity of an institution in its founding and how the institution has evolved and changed in response to the claims and context of social and historic dynamics. Thus, these six essays are harmonized by a three-fold critical-creative structure that attends to the dynamic experience of the call and spirit of mercy modeled in the founding of the University, how we presently live this call, and envision the challenges and possibilities that lie on the horizon. We employed the perspectives of Foundations, Living Presence, and Horizons to frame an analogical exploration of the unique character, actions and ideals that have inspired and sustained the vocation and mission of Salve Regina University, and may be creatively transferred to shaping the horizon for future generations of students.Celebrating the 75th anniversary of the founding of Salve Regina University, we invite readers to reflect on this collection of essays and then to join the conversations that are to follow as we continue to discern the path forward as Salve takes its next steps into the future.https://digitalcommons.salve.edu/fac_staff_ebooks/1006/thumbnail.jp

Proliferation of Ty3/gypsy-like retrotransposons in hybrid sunflower taxa inferred from phylogenetic data

<p>Abstract</p> <p>Background</p> <p>Long terminal repeat (LTR) retrotransposons are a class of mobile genetic element capable of autonomous transposition via an RNA intermediate. Their large size and proliferative ability make them important contributors to genome size evolution, especially in plants, where they can reach exceptionally high copy numbers and contribute substantially to variation in genome size even among closely related taxa. Using a phylogenetic approach, we characterize dynamics of proliferation events of <it>Ty3/gypsy</it>-like LTR retrotransposons that led to massive genomic expansion in three <it>Helianthus </it>(sunflower) species of ancient hybrid origin. The three hybrid species are independently derived from the same two parental species, offering a unique opportunity to explore patterns of retrotransposon proliferation in light of reticulate evolutionary events in this species group.</p> <p>Results</p> <p>We demonstrate that <it>Ty3/gypsy</it>-like retrotransposons exist as multiple well supported sublineages in both the parental and hybrid derivative species and that the same element sublineage served as the source lineage of proliferation in each hybrid species' genome. This inference is based on patterns of species-specific element numerical abundance within different phylogenetic sublineages as well as through signals of proliferation events present in the distributions of element divergence values. Employing methods to date paralogous sequences within a genome, proliferation events in the hybrid species' genomes are estimated to have occurred approximately 0.5 to 1 million years ago.</p> <p>Conclusion</p> <p>Proliferation of the same retrotransposon major sublineage in each hybrid species indicates that similar dynamics of element derepression and amplification likely occurred in each hybrid taxon during their formation. Temporal estimates of these proliferation events suggest an earlier origin for these hybrid species than previously supposed.</p

Analysis of protein-coding genetic variation in 60,706 humans

Large-scale reference data sets of human genetic variation are critical for the medical and functional interpretation of DNA sequence changes. We describe the aggregation and analysis of high-quality exome (protein-coding region) sequence data for 60,706 individuals of diverse ethnicities generated as part of the Exome Aggregation Consortium (ExAC). This catalogue of human genetic diversity contains an average of one variant every eight bases of the exome, and provides direct evidence for the presence of widespread mutational recurrence. We have used this catalogue to calculate objective metrics of pathogenicity for sequence variants, and to identify genes subject to strong selection against various classes of mutation; identifying 3,230 genes with near-complete depletion of truncating variants with 72% having no currently established human disease phenotype. Finally, we demonstrate that these data can be used for the efficient filtering of candidate disease-causing variants, and for the discovery of human “knockout” variants in protein-coding genes

Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution.

Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are dsDNA tailed phages, and have either siphoviral or myoviral morphotypes. However, their genetic diversity is considerable, and although sixty-two genomes have been sequenced and comparatively analyzed, these likely represent only a small portion of the diversity of the mycobacteriophage population at large. Here we report the isolation, sequencing and comparative genomic analysis of 18 new mycobacteriophages isolated from geographically distinct locations within the United States. Although no clear correlation between location and genome type can be discerned, these genomes expand our knowledge of mycobacteriophage diversity and enhance our understanding of the roles of mobile elements in viral evolution. Expansion of the number of mycobacteriophages grouped within Cluster A provides insights into the basis of immune specificity in these temperate phages, and we also describe a novel example of apparent immunity theft. The isolation and genomic analysis of bacteriophages by freshman college students provides an example of an authentic research experience for novice scientists