Trace-class operators on Hilbert modules and Haagerup tensor products

We show that the space of trace-class operators on a Hilbert module over a commutative C*-algebra, as defined and studied in earlier work of Stern and van Suijlekom (Journal of Functional Analysis, 2021), is completely isometrically isomorphic to a Haagerup tensor product of the module with its operator-theoretic adjoint. This generalises a well-known property of Hilbert spaces. In the course of proving this, we also obtain a new proof of a result of Stern-van Suijlekom concerning the equivalence between two definitions of trace-class operators on Hilbert modules.Comment: 13 page

Higher Vitamin D2 and 25(OH)D2, but Not Vitamin D3 Metabolites, in Bovine Plasma and Muscle from Grass-Based Finishing System, Compared to Concentrate

Meat and meat products are one of the largest contributors to vitamin D dietary intakes. Little is known, however, about how different animal husbandry practices and/or finishing diets might affect the vitamin D content of the animal. Therefore, this study aimed to investigate the effect of bovine finishing diet (grass vs. concentrate) on the 25(OH)D plasma concentrations of cattle and subsequent vitamin D content in beef. Cattle were fed grass (n = 7) or concentrate (n = 9) finishing diets for 15 weeks prior to slaughter. Bovine blood samples were collected at slaughter and plasma aliquots were stored (−80 °C) until analysis. Beef top rump from each animal was chilled for an ageing period of 21 days, then homogenised and frozen (−80 °C) until analysis. Bovine plasma samples were analysed for circulating 25(OH)D3, and 25(OH)D2 (nmol/L), and raw beef muscle (top rump) samples were analysed for vitamin D metabolites; vitamin D3, vitamin D2, 25(OH)D3 and 25(OH)D2 (µg/kg), all by LC-MS/MS. Total vitamin D activity was defined: [vitamin D3 + (25(OH)D3 × 5) + vitamin D2 + (25(OH)D2 × 5)]. Statistical analysis was conducted by SPSS with independent t tests used to compare groups; significance level p < 0.05. Data were presented as mean ± SD. A significantly higher plasma 25(OH)D2 concentration was observed in the grass finished cattle compared to the concentrate group (43.18 ± 11.75 vs. 16.56 ± 1.58 nmol/L, p < 0.002). No difference in plasma 25(OH)D3 concentrations was observed between groups. In beef top rump, the grass finishing diet resulted in a significantly higher mean ± SD vitamin D2 [0.07 ± 0.05 vs. 0.01 ± 0.01 µg/kg] and 25(OH)D2 [0.70 ± 0.16 vs. 0.25 ± 0.07 µg/kg] compared to concentrate finishing diet (both p < 0.001). Moreover, beef from grass finished cattle demonstrated a significantly higher total vitamin D activity compared to those in the concentrate group [9.52 ± 2.43 vs. 6.78 ± 2.00 µg/kg, p < 0.05]. No difference was observed for muscle vitamin D3 or 25(OH)D3 between groups. In conclusion, a more favourable bovine vitamin D profile, driven by vitamin D2 metabolites specifically (not vitamin D3), is reported from a grass-based finished system, compared to concentrate finishing. Further research is required to understand the impact of these findings for both agriculture practices and human nutrition

Mastocytosis: a Rare Case of Anaphylaxis in Paediatric Age and Literature Review

The term “mastocytosis” denotes a heterogeneous group of disorders characterised by abnormal growth and accumulation of mast cells (MC) in one or more organ systems. Symptoms result from MC chemical mediator’s release, pathologic infiltration of neoplastic MC in tissues or both. Multiple molecular, genetic and chromosomal defects seem to contribute to an autonomous growth, but somatic c-kit D816V mutation is more frequently encountered, especially in systemic disease. We present a literature review of mastocytosis and a rare case report of an 18 month-old-girl with a bullous dermatosis, respiratory distress and anaphylaxis, as clinical manifestations of mastocytosis. The developments of accepted classification systems and novel useful markers allowed a re-evaluation and updating of the classification of mastocytosis. In paediatric age cutaneous forms of disease prevail and may regress spontaneously. SM is more frequently diagnosed in adults and is a persistent(clonal) disease of bone marrow. The clinical course in these patients is variable.Today diagnostic criteria for each disease variant are reasonably well defined. There are, however, peculiarities, namely in paediatric age, that makes the diagnostic approach difficult. Systemic disease may pose differential diagnostic problems resulting from multiple organ systems involvement. Coversly, the “unexplained” appearance of those symptoms with no skin lesions should raise the suspicion of MC disease. This case is reported in order to stress the clinical severity and difficult diagnostic approach that paediatric mastocytosis may assume

Improving vitamin D content in pork meat by UVB biofortification

Publication history: Accepted - 11 January 2023; Published online - 14 January 2023Vitamin D deficiency is prevalent worldwide and identification of alternative food-based strategies are urgently warranted. In two studies, 12-week old crossbred pigs (Duroc x (Large White x Landrace)) were exposed daily to narrowband UVB radiation for ∼10 weeks or control (no UVB exposure) until slaughter. In Study 1 (n = 48), pigs were exposed to UVB for 2 min and in Study 2 (n = 20), this duration was tripled to 6 min. All pigs were fed the maximum permitted 2000 IU vitamin D3/kg feed. Loin meat was cooked prior to vitamin D LC-MS/MS analysis. In Study 1, pork loin vitamin D3 did not differ between groups. Study 2 provided longer UVB exposure time and resulted in significantly higher loin vitamin D3 (11.97 vs. 6.03 μg/kg), 25(OH)D3 (2.09 vs. 1.65 μg/kg) and total vitamin D activity (22.88 vs. 14.50 μg/kg) concentrations, compared to control (P < 0.05). Pigs remained healthy during both studies and developed no signs of erythema. Biofortification by UVB radiation provides an effective strategy to further safely increase the naturally occurring vitamin D content of pork loin, alongside feed supplementationThis work was funded as part of a Department for the Economy (DfE) Co-operative Awards in Science and Technology (CAST) PhD studentship, supported by Devenish Nutrition Limited and Agri-Food Quest Competence Centre (AFQCC)

La diversidad y la densidad de las epífitas vasculares en la Reserva Cerro Candelaria: La diferencia entre las alturas y dos tipos de bosque nublado en Ecuador

En el bosque nublado, las epífitas son muy comunes por la neblina, o la “lluvia horizontal,” que permite el crecimiento de plantas sobre otras plantas. También, las epífitas son contribuidoras importantes para el crecimiento y mantenimiento de un bosque nublado saludable. Las epífitas pueden estar afectadas por la deforestación, y este ensayo investiga las diferencias entre la distribución, la densidad, y la biodiversidad de las epífitas en el bosque nublado primario y secundario. El estudio consiste en cuadrantes realizados en cuatro niveles de altura, y en el bosque primario y secundario adentro y cerca de la Reserva Cerro Candelaria, todo en el corredor ecológico entre los parques nacionales ecuatorianos los Llanganates y El Sangay. Elegí estudiar solo epífitas vasculares. En los cuadrantes que estudié, no encontré una relación fuerte entre la riqueza de epífitas y el diámetro del árbol hospedero, pero hay diferencias de la distribución de los géneros entre el bosque primario y el bosque secundario. Hay más densidad en el número de epífitas con relación al diámetro del árbol en el bosque secundario que en el bosque primario. La diversidad es distintivamente más grande en el bosque primario que en el bosque secundario, y la composición de los géneros entre los dos tipos de bosque es muy distinta. También la dispersión de los individuos en sus géneros respectivos es más uniforme en el bosque primario que en el bosque secundario. La diversidad y la densidad de las epífitas en el bosque primario aumentaba en una relación directa con la altura, pero no había una correlación entre la densidad y la altura, ni entre la diversidad y la altura en el bosque secundario