Evaluation of chondroprotective effect of glucosamine and chondroitin sulfate by a proteomic approach

Comunicaciones a congreso

Hypoxia conditions differentially modulate normal and osteoarthritic chondrocyte proteomes

Comunicaciones a congreso

Rotavirus VP6 nanotubes show an antigen form-dependent adjuvant activity: Zika virus envelope protein monomer vs Zika virus-like particles

The structural protein of rotavirus (RV) VP6 can self-assemble into tubular polymeric structures under specific conditions of pH and ionic strength when expressed in recombinant systems. Previous studies have shown that RV VP6 nanotubes (VP6NT) have an adjuvant effect on the immunogenicity of norovirus virus-like particles (VLPs) in mice (Blazevic et al., 2011; Malm et al., 2016). The present study focused on the determination of adjuvant activity of VP6NT on the immunogenicity of monomers of the viral envelope (E) protein or of Zika virus (ZikV) VLPs. ZikV infection can cause congenital malformations in fetuses and the Guillain-Barré syndrome in adults, as the most severe consequences. To date, there is no treatment or vaccine available against ZikV. Several vaccine candidates against this virus have been reported and E protein has been selected as the primary antigenic determinant. Please click Download on the upper right corner to see the full abstract

Use of Phragmites australis for controlling phospohrus contamination in anthropogenic wetland ecosystems

This is an Author's Accepted Manuscript of an article published in J. M. Carricondo, J. V. Oliver-Villanueva, J. V. Turégano, J. A. González & J. Mengual (2021) Use of Phragmites australis for controlling phosphorus contamination in anthropogenic wetland ecosystems, Environmental Technology, 42:19, 3055-3064, DOI: 10.1080/09593330.2020.1720311 [copyright Taylor & Francis], available online at: http://www.tandfonline.com/10.1080/09593330.2020.1720311[EN] Continuous phosphorus discharges in bodies of water, generated by human activities, such as agriculture, domestic effluences or wastewater from industrial processes, produce contaminated water and eutrophication. For this reason, efficient and low-cost systems that can remove phosphorus from contaminated water are necessary. In addition, it is important to generate renewable energy such as the energy produced in biomass power plants, taking advantage of the available biomass waste in each place. When producing this renewable energy, the resulting ash is a residue that can be used for phosphorus removal by adsorption processes. Moreover, according to the concept of the circular economy, the ash waste generated in this bio energy process should be reduced as much as possible. One of the advantages of this research being that surplus phosphorus-laden ash can be reused as fertilizer in agricultural fields. Considering this, the efficiency of reed ash (RA) (Phragmites australis) has been analysed in batch experiments, as well as the effect of several parameters on the removal of phosphate, such as contact time, phosphate-ash ratio, ash dose and temperature. Significant results obtained show that RA can be used to improve water quality.Carricondo, JM.; Oliver Villanueva, JV.; Turegano Pastor, JV.; González Romero, JA.; Mengual Cuquerella, J. (2021). Use of Phragmites australis for controlling phospohrus contamination in anthropogenic wetland ecosystems. 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The supplementation with Resveratrol and α-Tocopherol could reduce the risk of sarcopenia in dogs by counteracting the oxidative stress

Several scienti\ufb01c evidences show that oxidative stress is associated with the origin, progression and severity of chronic noncommunicable diseases. Due to the longer duration of life, sarcopenia, osteopenia, osteoporosis and cachexia are considered emerging syndromes for dogs and cats. The objective was to investigate the impact of a supplementation with resveratrol and -tocopherol (JUVENIA \uae ) on the harmful effects of oxidative stress in adult dogs. The study was able to demonstrate this supplementation was able to positively modulate creatine phosphokinase and alkaline phosphatase, which are considered useful biomarkers for sarcopenia, bone formation and speed in bone remodeling. As a result of the longer life of domestic animals and, in particular dogs, the use of food supplements with antioxidant activity could play a critical role in reducing/delaying the onset of chronic-degenerative diseases. On the basis of the present study, the use of products containing resveratrol and -tocopherol acetate seems to be a promising approach for improving the health of dogs