Photoproduction of K+ Δ(1405) → K+ π0 Σ0 extending to forward angles and low momentum transfer

K+ Lambda (1405) photoproduction has been studied at the BGOOD experiment via the all neutral decay, Lambda(1405)-> Sigma0 Pi0. The unique BGOOD experimental setup allows both the cross section and invariant mass Lamba(1405) distribution (line shape) to be measured over a broad K+ polar angle range, extending to extreme forward K+ angles unattainable at previous experiments. Evidence is provided for the role of a triangle singularity driven by the N*(2030)⁎ resonance, which appears to contribute significantly to K+Lambda(1405) photoproduction. This is observed in the integrated cross section which was determined with unprecedented energy resolution and supported by the angular distributions. The measured line shape is also in agreement with the previous results of CLAS and ANKE, and is consistent with two poles derived in χPT based models

Erratum to: Strangeness Photoproduction at the BGO-OD Experiment

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Blunted Medial Prefrontal Cortico-Limbic Reward-Related Effective Connectivity and Depression

Stratifying Resilience and Depression Longitudinally (STRADL) was supported by the Wellcome Trust through a Strategic Award (Grant No. 104036/Z/14/Z). Parts of the work were supported by a China Scholarship Council (Grant No. 201506040037 to SX), National Institutes of Health (Grant No. DA027764 to MRD), Lister Institute Prize Fellowship 2016–2021 (to DJS), Dr Mortimer and Theresa Sackler Foundation (AMM, HCW, and SML), Centre for Cognitive Ageing and Cognitive Epidemiology (IJD and AMM), Medical Research Council and Biotechnology and Biological Sciences Research Council (Grant No. MR/K026992/1), Royal College of Physicians of Edinburgh John, Margaret, Alfred and Stewart Sim fellowship (to HCW), and University of Edinburgh, Edinburgh Scientific Academic TmPCk College Fellowship (to HCW). The Chief Scientist Office of the Scottish Government Health Department (Grant No. CZD/16/6) and Scottish Funding Council (Grant No. HR03006) provided core support for Generation Scotland. Data acquisition was additionally supported by the Scottish Mental Health Research Network and Scottish Government’s Support for Science initiative. LR, HCW, and AMM, received financial support from Pfizer (formerly Wyeth) in relation to imaging studies of people with schizophrenia and bipolar disorder. AMM has previously received grant support from Lilly and Janssen. SML has received honoraria for lectures, chairing meetings, and consultancy work from Janssen in connection with brain imaging and therapeutic initiatives for psychosis. JDS has received funding via an honorarium associated with a lecture or Wyeth and funding from Indivior for a study on opioid dependency. No other disclosures were reported. The authors declare no conflict of interest.Peer reviewedPublisher PD

Evidence of a dibaryon spectrum in coherent π0π0d photoproduction at forward deuteron angles

The coherent reaction, was studied with the BGOOD experiment at ELSA from threshold to a centre-of-mass energy of 2850 MeV. A full kinematic reconstruction was made, with final state deuterons identified in the forward spectrometer and decays in the central BGO Rugby Ball. The strength of the differential cross section exceeds what can be described by models of coherent photoproduction and instead supports the three isoscalar dibaryon candidates reported by the ELPH collaboration at 2.38, 2.47 and 2.63 GeV/c2. A low mass enhancement in the invariant mass is also observed at the ⁎ centre-of-mass energy which is consistent with the ABC effect. At higher centre-of-mass energies, a narrow peak in the invariant mass at 2114 MeV/c2 with a width of 20 MeV/c2 supports a sequential two-dibaryon decay mechanism

Quantitative Bias in Illumina TruSeq and a Novel Post Amplification Barcoding Strategy for Multiplexed DNA and Small RNA Deep Sequencing

Here we demonstrate a method for unbiased multiplexed deep sequencing of RNA and DNA libraries using a novel, efficient and adaptable barcoding strategy called Post Amplification Ligation-Mediated (PALM). PALM barcoding is performed as the very last step of library preparation, eliminating a potential barcode-induced bias and allowing the flexibility to synthesize as many barcodes as needed. We sequenced PALM barcoded micro RNA (miRNA) and DNA reference samples and evaluated the quantitative barcode-induced bias in comparison to the same reference samples prepared using the Illumina TruSeq barcoding strategy. The Illumina TruSeq small RNA strategy introduces the barcode during the PCR step using differentially barcoded primers, while the TruSeq DNA strategy introduces the barcode before the PCR step by ligation of differentially barcoded adaptors. Results show virtually no bias between the differentially barcoded miRNA and DNA samples, both for the PALM and the TruSeq sample preparation methods. We also multiplexed miRNA reference samples using a pre-PCR barcode ligation. This barcoding strategy results in significant bias

Observation of a cusp-like structure in the γp → K+Σ0 cross section at forward angles and low momentum transfer

The gamma+p->K+ + Sigma0 differential cross section at extremely forward angles was measured at the BGOOD experiment. A three-quarter drop in strength over a narrow range in energy and a strong dependence on the polar angle of the in the centre-of-mass of the reaction is observed at a centre-of-mass energy of 1900 MeV. Residing close to multiple open and hidden strangeness thresholds, the structure appears consistent with meson-baryon threshold effects which may contribute to the reaction mechanism