Водоотведение на ООО "Пивоварня Кожевниково" (Томская область)

Объектом исследования является очистные сооружения. Цель работы – изучение эколого-экономического состояния очистных сооружений на ООО «Пивоварня Кожевниково» г. Томска. В процессе исследования проводились следующие виды работ: отбор проб и их транспортировка в гидрогеохимическую и микробиологическую лабораторию СНИИГГиМС г. Томска; анализ и интерпретация полученных результатов химического составов вод; проведение эколого-экономической оценки очистных сооружений; В результате исследования получены новые данные о содержании веществ в подземных водах, проанализировано воздействие природных и антропогенных факторов на экологическое состояние подземных вод и прилегающей территории, оценено качество сточных вод. Основные конструктивные, технологические и технико-эксплуатационные характеристики: комплексное использование очистных сооружений и станции водоподготовки. Степень внедрения: научно-исследовательские работы.The CWA (Clean Water Act) established a control program for ensuring that communities have clean water by regulating the release of contaminants into our country’s waterways

Zum Begriff der wissenschaftlichen Arbeit im "Kapital"

Im "Kapital" taucht der Begriff der wissenschaftlichen Arbeit nur am Rande auf, obwohl die wissenschaftliche Arbeit für die Produktion des relativen Mehrwerts entscheidend ist. Welche Implikationen dieser Begriff hat und warum die wissenschaftliche Arbeit wesentlich gebrauchswertbildend aber nicht wertbildend ist, kann anhand der Marxschen Bestimmungen im "Kapital" deutlich gemacht werden

An ancient pathway combining carbon dioxide fixation with the generation and utilization of a sodium ion gradient for ATP synthesis

Synthesis of acetate from carbon dioxide and molecular hydrogen is considered to be the first carbon assimilation pathway on earth. It combines carbon dioxide fixation into acetyl-CoA with the production of ATP via an energized cell membrane. How the pathway is coupled with the net synthesis of ATP has been an enigma. The anaerobic, acetogenic bacterium Acetobacterium woodii uses an ancient version of this pathway without cytochromes and quinones. It generates a sodium ion potential across the cell membrane by the sodium-motive ferredoxin:NAD oxidoreductase (Rnf). The genome sequence of A. woodii solves the enigma: it uncovers Rnf as the only ion-motive enzyme coupled to the pathway and unravels a metabolism designed to produce reduced ferredoxin and overcome energetic barriers by virtue of electron-bifurcating, soluble enzymes

The effect of CpG-ODN on antigen presenting cells of the foal

BACKGROUND: Cytosine-phosphate-guanosine oligodeoxynucleotide (CpG-ODN) has been used successfully to induce immune responses against viral and intracellular organisms in mammals. The main objective of this study was to test the effect of CpG-ODN on antigen presenting cells of young foals. METHODS: Peripheral blood monocytes of foals (n = 7) were isolated in the first day of life and monthly thereafter up to 3 months of life. Adult horse (n = 7) monocytes were isolated and tested once for comparison. Isolated monocytes were stimulated with IL-4 and GM-CSF (to obtain dendritic cells, DC) or not stimulated (to obtain macrophages). Macrophages and DCs were stimulated for 14-16 hours with either CpG-ODN, LPS or not stimulated. The stimulated and non-stimulated cells were tested for cell surface markers (CD86 and MHC class II) using flow cytometry, mRNA expression of cytokines (IL-12, IFNalpha, IL-10) and TLR-9 using real time quantitative RT-PCR, and for the activation of the transcription factor NF-kappaB p65 using a chemiluminescence assay. RESULTS: The median fluorescence of the MHC class II molecule in non-stimulated foal macrophages and DCs at birth were 12.5 times and 11.2 times inferior, respectively, than adult horse cells (p = 0.009). That difference subsided at 3 months of life (p = 0.3). The expression of the CD86 co-stimulatory molecule was comparable in adult horse and foal macrophages and DCs, independent of treatment. CpG-ODN stimulation induced IL-12p40 (53 times) and IFNalpha (23 times) mRNA expression in CpG-ODN-treated adult horse DCs (p = 0.078), but not macrophages, in comparison to non-stimulated cells. In contrast, foal APCs did not respond to CpG-ODN stimulation with increased cytokine mRNA expression up to 3 months of age. TLR-9 mRNA expression and NF-kB activation (NF-kB p65) in foal DCs and macrophages were comparable (p \u3e 0.05) to adult horse cells. CONCLUSION: CpG-ODN treatment did not induce specific maturation and cytokine expression in foal macrophages and DCs. Nevertheless, adult horse DCs, but not macrophages, increased their expression of IL-12 and IFNalpha cytokines upon CpG-ODN stimulation. Importantly, foals presented an age-dependent limitation in the expression of MHC class II in macrophages and DCs, independent of treatment

Complete genome sequence of Staphylococcus aureus 6850, a highly cytotoxic and clinically virulent Methicillin-sensitive strain with distant relatedness to prototype strains

Staphylococcus aureus is a frequent human commensal bacterium and pathogen. Here we report the complete genome sequence of strain 6850 (spa type t185; sequence type 50 [ST50]), a highly cytotoxic and clinically virulent methicillin-sensitive strain from a patient with complicated S. aureus bacteremia associated with osteomyelitis and septic arthritis

Внедрение концепции бережливого производства на электротехническом предприятии

Выпускная квалификационная работа содержит 86 страниц, 6 рисунков, 32 таблицы, 20 использованных источников, 4 приложения. Цель работы – разработать практические предложения для оптимизации и совершенствования производственного процесса «Наложение изоляции на кабель» в ООО «ТомскКабель». В результате исследования были предложены мероприятия по совершенствованию производственного процесса «Наложение изоляции на кабель», а также проведена оценка эффективности реализации данных мероприятий.Graduate qualification work consists of 86 pages, 6 figures, 32 tables, 20 sources used, 4 attachments. The purpose is to create a practice suggestion for increasing production line efficiency by using Lean Manufacturing tools. As a result of research several measures on the operating process of the line of application of cable insulation LTD «TomskCable» development were elaborated and offered to the company, measures efficiency was evaluated