6 Is there a legitimation crisis of the nation-state?

It is widely accepted that internationalization and the increasing loss of parliamentary control over political power challenge the legitimacy of national democratic systems and their core institutions. We first present results from a study of public communication, which, when examined in the context of theories of legitimation, indicate that these processes do not necessarily lead to the erosion or breakdown of popular support for the nation state. The idea that there is a linear cause-and-effect relationship is overly simple, and a more detailed analysis is called for. Legitimation of a political system through public communication is a back-and-forth process which is determined by the system s specific institutional arrangements and by the fortuitous twists and turns of public debate. Nation states have more extensive, diverse and deeply rooted sources of legitimation than is often assumed.

The democratic nationa state: Erosion, or transformation, of legitimacy: 6 Is there a legitimation crisis of the nation-state?

It is widely accepted that internationalization and the increasing loss of parliamentary control over political power challenge the legitimacy of national democratic systems and their core institutions. We first present results from a study of public communication, which, when examined in the context of theories of legitimation, indicate that these processes do not necessarily lead to the erosion or breakdown of popular support for the nation state. The idea that there is a linear cause-and-effect relationship is overly simple, and a more detailed analysis is called for. Legitimation of a political system through public communication is a back-and-forth process which is determined by the system's specific institutional arrangements and by the fortuitous twists and turns of public debate. Nation states have more extensive, diverse and deeply rooted sources of legitimation than is often assumed

Is there a legitimation crisis of the nation state?

It is widely accepted that internationalization and the increasing loss of parliamentary control over political power challenge the legitimacy of national democratic systems and their core institutions. We first present results from a study of public communication, which, when examined in the context of theories of legitimation, indicate that these processes do not necessarily lead to the erosion or breakdown of popular support for the nation state. The idea that there is a linear cause-and-effect relationship is overly simple, and a more detailed analysis is called for. Legitimation of a political system through public communication is a back-and-forth process which is determined by the system’s specific institutional arrangements and by the fortuitous twists and turns of public debate. Nation states have more extensive, diverse and deeply rooted sources of legitimation than is often assumed. Legitimacy in the nation-state: what do we know? The idea of democracy is at the heart of the modern western state, whose institutions reflect what Robert A. Dahl called the ‘second democratic transformation’, i.e. the transfer of democratic self-government from the city-state to nations and large-scale societies. For a long time, this transfer was remarkably successful. Institutions of representative democracy at the national level secured effective citizen participation in political decision-making and they themselves became a central source of popular support for the nation state’s political arrangements

Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases.

Many autoimmune diseases (ADs) share similar underlying pathology and have a tendency to cluster within families, supporting the involvement of shared susceptibility genes. To date, most of the genetic variants associated with systemic lupus erythematosus (SLE) susceptibility also show association with others ADs. ITGAM and its associated 'predisposing' variant (rs1143679, Arg77His), predicted to alter the tertiary structures of the ligand-binding domain of ITGAM, may play a key role for SLE pathogenesis. The aim of this study is to examine whether the ITGAM variant is also associated with other ADs. We evaluated case-control association between rs1143679 and ADs (N=18,457) including primary Sjögren's syndrome, systemic sclerosis, multiple sclerosis, rheumatoid arthritis, juvenile idiopathic arthritis, celiac disease, and type-1 diabetes. We also performed meta-analyses using our data in addition to available published data. Although the risk allele 'A' is relatively more frequent among cases for each disease, it was not significantly associated with any other ADs tested in this study. However, the meta-analysis for systemic sclerosis was associated with rs1143679 (p(meta)=0.008). In summary, this study explored the role of ITGAM in general autoimmunity in seven non-lupus ADs, and only found association for systemic sclerosis when our results were combined with published results. Thus ITGAM may not be a general autoimmunity gene but this variant may be specifically associated with SLE and systemic sclerosis