9 research outputs found
Correlaci贸n cito-histol贸gica del tumor papilar de la gl谩ndula pineal. Presentaci贸n de un caso
En la 煤ltima revisi贸n de la Organizaci贸n Mundial de la Salud (OMS) en relaci贸n a los tumores del sistema nervioso central (SNC), se describieron nuevas entidades, como el Tumor Papilar de la Gl谩ndula Pineal. Esta lesi贸n de rara aparici贸n, se ha identificado en adultos j贸venes. El diagn贸stico de estos tumores es complejo ya que depende de su ubicaci贸n, edad de aparici贸n y el aspecto histol贸gico; 茅ste 煤ltimo tiene similitudes con otras lesiones como el ependimoma papilar o el papiloma/carcinoma de plexos coroides. Citol贸gicamente presentan caracter铆sticas claras que pueden ayudar al diagn贸stico a trav茅s de la impronta en el estudio intraoperatorio; reconocer ciertos criterios con 茅ste importante y sencillo m茅todo diagn贸stico ha sido la motivaci贸n principal para el estudio de entidades poco frecuentes del SNC, adem谩s de corroborar el necesario trabajo de un equipo multidisciplinar
Correlaci贸n cito-histol贸gica del tumor papilar de la gl谩ndula pineal. Presentaci贸n de un caso
En la 煤ltima revisi贸n de la Organizaci贸n Mundial de la Salud (OMS) en relaci贸n a los tumores del sistema nervioso central (SNC), se describieron nuevas entidades, como el Tumor Papilar de la Gl谩ndula Pineal. Esta lesi贸n de rara aparici贸n, se ha identificado en adultos j贸venes. El diagn贸stico de estos tumores es complejo ya que depende de su ubicaci贸n, edad de aparici贸n y el aspecto histol贸gico; 茅ste 煤ltimo tiene similitudes con otras lesiones como el ependimoma papilar o el papiloma/carcinoma de plexos coroides. Citol贸gicamente presentan caracter铆sticas claras que pueden ayudar al diagn贸stico a trav茅s de la impronta en el estudio intraoperatorio; reconocer ciertos criterios con 茅ste importante y sencillo m茅todo diagn贸stico ha sido la motivaci贸n principal para el estudio de entidades poco frecuentes del SNC, adem谩s de corroborar el necesario trabajo de un equipo multidisciplinar
Correlaci贸n cito-histol贸gica del tumor papilar de la gl谩ndula pineal. Presentaci贸n de un caso
En la 煤ltima revisi贸n de la Organizaci贸n Mundial de la Salud (OMS) en relaci贸n a los tumores del sistema nervioso central (SNC), se describieron nuevas entidades, como el Tumor Papilar de la Gl谩ndula Pineal. Esta lesi贸n de rara aparici贸n, se ha identificado en adultos j贸venes. El diagn贸stico de estos tumores es complejo ya que depende de su ubicaci贸n, edad de aparici贸n y el aspecto histol贸gico; 茅ste 煤ltimo tiene similitudes con otras lesiones como el ependimoma papilar o el papiloma/carcinoma de plexos coroides. Citol贸gicamente presentan caracter铆sticas claras que pueden ayudar al diagn贸stico a trav茅s de la impronta en el estudio intraoperatorio; reconocer ciertos criterios con 茅ste importante y sencillo m茅todo diagn贸stico ha sido la motivaci贸n principal para el estudio de entidades poco frecuentes del SNC, adem谩s de corroborar el necesario trabajo de un equipo multidisciplinar
Clinical and pathological features of Merkel cell carcinoma: A 4-year follow-up observational retrospective study in Spain
Background: Merkel cell carcinoma (MCC) is a malignant skin cancer with a 5-year survival rate of approximately
50%. Knowledge of MCC has increased in recent years mostly due to improved diagnosis techniques. In Spain
there is lack of information regarding the incidence and tumour characteristics, and the treatment approaches are not standardised. The objective of this study was to provide information of the clinical and epidemiological
characteristics of MCC patients in Spain.
Methods: Retrospective, observational study involving 192 patients from 25 Spanish hospitals. Evaluated vari ables included overall survival and incidence rate of Merkel cell polyomavirus, in patients diagnosed from 2012
to 2016.
Results: The Spanish incidence rate was estimated 0.32/100,000 inhabitants/year, with variations according to
geographical regions, being slightly higher in areas with greater sunlight exposure. In total, 61.5% of tumours
showed expansive growth (progressive growth of the tumour), 78.6% showed localisation in UV-exposed skin.
97.4% of patients were diagnosed by excisional biopsy. Surgery was the first line treatment in 96.6% of patients,
radiotherapy in 24.6%, and chemotherapy in 6.3%. These treatments were not mutually exclusive. Median
overall survival was 38.3 months (78.4% at 12 months and 60% at 24 months). MCPyV was present in 33.8% of
patients.
Conclusion: The incidence of MCC in Spain is one of the highest in Europe, with a slight predominance in men.
The sample has shown that a biopsy is available for diagnosis in most cases. Moreover, the treatment is surgical
when the tumour is localized and is associated with lymphadenectomy, and/or it is radiotherapy if widespread
Correlaci贸n cito-histol贸gica del tumor papilar de la gl谩ndula pineal. Presentaci贸n de un caso
En la 煤ltima revisi贸n de la Organizaci贸n Mundial de la Salud (OMS) en relaci贸n a los tumores del sistema nervioso central (SNC), se describieron nuevas entidades, como el Tumor Papilar de la Gl谩ndula Pineal. Esta lesi贸n de rara aparici贸n, se ha identificado en adultos j贸venes. El diagn贸stico de estos tumores es complejo ya que depende de su ubicaci贸n, edad de aparici贸n y el aspecto histol贸gico; 茅ste 煤ltimo tiene similitudes con otras lesiones como el ependimoma papilar o el papiloma/carcinoma de plexos coroides. Citol贸gicamente presentan caracter铆sticas claras que pueden ayudar al diagn贸stico a trav茅s de la impronta en el estudio intraoperatorio; reconocer ciertos criterios con 茅ste importante y sencillo m茅todo diagn贸stico ha sido la motivaci贸n principal para el estudio de entidades poco frecuentes del SNC, adem谩s de corroborar el necesario trabajo de un equipo multidisciplinar
Advanced type 1 hyperoxaluria presenting as livedo racemosa in a patient with end-stage renal disease
LEA 10. Experimental Model to Assess the Safety of Energy Sealing Devices in Saphenous Vein Graft in Bypass Surgery
Clinical and pathological features of Merkel cell carcinoma: A 4-year follow-up observational retrospective study in Spain.
Merkel cell carcinoma (MCC) is a malignant skin cancer with a 5-year survival rate of approximately 50%. Knowledge of MCC has increased in recent years mostly due to improved diagnosis techniques. In Spain there is lack of information regarding the incidence and tumour characteristics, and the treatment approaches are not standardised. The objective of this study was to provide information of the clinical and epidemiological characteristics of MCC patients in Spain. Retrospective, observational study involving 192 patients from 25 Spanish hospitals. Evaluated variables included overall survival and incidence rate of Merkel cell polyomavirus, in patients diagnosed from 2012 to 2016. The Spanish incidence rate was estimated 0.32/100,000 inhabitants/year, with variations according to geographical regions, being slightly higher in areas with greater sunlight exposure. In total, 61.5% of tumours showed expansive growth (progressive growth of the tumour), 78.6% showed localisation in UV-exposed skin. 97.4% of patients were diagnosed by excisional biopsy. Surgery was the first line treatment in 96.6% of patients, radiotherapy in 24.6%, and chemotherapy in 6.3%. These treatments were not mutually exclusive. Median overall survival was 38.3 months (78.4% at 12 months and 60% at 24 months). MCPyV was present in 33.8% of patients. The incidence of MCC in Spain is one of the highest in Europe, with a slight predominance in men. The sample has shown that a biopsy is available for diagnosis in most cases. Moreover, the treatment is surgical when the tumour is localized and is associated with lymphadenectomy, and/or it is radiotherapy if widespread