Rocket study of the X-ray background

The X-ray optical detection system flown on Aerobee 17.08 is described in detail, and the preliminary results of the 24 June 1971 flight are discussed. The optical design, fabrication and parabolic nature of the mirrors, effective aperture of mirror array, and X-ray detectors are considered. Preliminary analysis of data from the flight confirms the extended nature and complex structure of the X-ray source in Virgo. A core of X-ray emission is indicated which is approximately 0.5 deg in diameter and surrounded by an emitting region at least 2 deg across. The Virgo source spectrum is observed to have few low energy photons

The Lockheed OSO-8 program. Analysis of data from the mapping X-ray heliometer experiment

The final report describes the extent of the analysis effort, and other activities associated with the preservation and documentation of the data set are described. The main scientific results, which are related to the behavior of individual solar activity regions in the energy band 1.5 - 15 keV, are summarized, and a complete bibliography of publications and presentations is given. Copies of key articles are also provided

Fourteen days of smoking cessation improves muscle fatigue resistance and reverses markers of systemic inflammation

Cigarette smoking has a negative effect on respiratory and skeletal muscle function and is a risk factor for various chronic diseases. To assess the effects of 14 days of smoking cessation on respiratory and skeletal muscle function, markers of inflammation and oxidative stress in humans. Spirometry, skeletal muscle function, circulating carboxyhaemoglobin levels, advanced glycation end products (AGEs), markers of oxidative stress and serum cytokines were measured in 38 non-smokers, and in 48 cigarette smokers at baseline and after 14 days of smoking cessation. Peak expiratory flow (p = 0.004) and forced expiratory volume in 1 s/forced vital capacity (p = 0.037) were lower in smokers compared to non-smokers but did not change significantly after smoking cessation. Smoking cessation increased skeletal muscle fatigue resistance (p < 0.001). Haemoglobin content, haematocrit, carboxyhaemoglobin, total AGEs, malondialdehyde, TNF-α, IL-2, IL-4, IL-6 and IL-10 (p < 0.05) levels were higher, and total antioxidant status (TAS), IL-12p70 and eosinophil numbers were lower (p < 0.05) in smokers. IL-4, IL-6, IL-10 and IL-12p70 had returned towards levels seen in non-smokers after 14 days smoking cessation (p < 0.05), and IL-2 and TNF-α showed a similar pattern but had not yet fully returned to levels seen in non-smokers. Haemoglobin, haematocrit, eosinophil count, AGEs, MDA and TAS did not significantly change with smoking cessation. Two weeks of smoking cessation was accompanied with an improved muscle fatigue resistance and a reduction in low-grade systemic inflammation in smokers

Predation increases multiple components of microbial diversity in activated sludge communities

We thank Severn Trent Waters for providing an access to the Derby waste-water treatment plant, and Peter Vale for his help in facilitating waste-water sampling at the site. Further, many thanks go to Richard Duff for his essential support during media preparation and laboratory assistance. We also thank two anonymous reviewers for their constructive feedback. This project was funded by internal support from Derby University to AB and from Queen Mary University of London to PK.Protozoan predators form an essential component of activated sludge communities that is tightly linked to wastewater treatment efficiency. Nonetheless, very little is known how protozoan predation is channelled via bacterial communities to affect ecosystem functioning. Therefore, we experimentally manipulated protozoan predation pressure in activated-sludge communities to determine its impacts on microbial diversity, composition and putative functionality. Different components of bacterial diversity such as taxa richness, evenness, genetic diversity and beta diversity all responded strongly and positively to high protozoan predation pressure. These responses were non-linear and levelled off at higher levels of predation pressure, supporting predictions of hump-shaped relationships between predation pressure and prey diversity. In contrast to predation intensity, the impact of predator diversity had both positive (taxa richness) and negative (evenness and phylogenetic distinctiveness) effects on bacterial diversity. Furthermore, predation shaped the structure of bacterial communities. Reduction in top-down control negatively affected the majority of taxa that are generally associated with increased treatment efficiency, compromising particularly the potential for nitrogen removal. Consequently, our findings highlight responses of bacterial diversity and community composition as two distinct mechanisms linking protozoan predation with ecosystem functioning in activated sludge communities.Derby UniversityQueen Mary University of Londo