New brazing alloy eliminates metal-stress cracking

Silver 15 zinc brazing alloy avoids the liquid- metal stress cracking of base metals when applied to 347, 316, and 410 stainless steels and certain other alloys

Extracting the depolarization coefficient D_NN from data measured with a full acceptance detector

The spin transfer from vertically polarized beam protons to Lambda or Sigma hyperons of the associated strangeness production pp -> pK Lambda (Sigma) is described with the depolarization coefficient D_NN. As the polarization of the hyperons is determined by their weak decays, detectors, which have a large acceptance for the decay particles, are needed. In this paper a formula is derived, which describes the depolarization coefficient D_NN by count rates of a 4 pi detector. It is shown, that formulas, which are given in publications for detectors with restricted acceptance, are specific cases of this formula for a 4 pi detector.Comment: Accepted for publication by Nuclear Instruments and Methods in Physics Research Section

Nuclear structure beyond the neutron drip line: the lowest energy states in 9^9He via their T=5/2 isobaric analogs in 9^9Li

The level structure of the very neutron rich and unbound $^9$He nucleus has been the subject of significant experimental and theoretical study. Many recent works have claimed that the two lowest energy $^9$He states exist with spins $J^\pi=1/2^+$ and $J^\pi=1/2^-$ and widths on the order of hundreds of keV. These findings cannot be reconciled with our contemporary understanding of nuclear structure. The present work is the first high-resolution study with low statistical uncertainty of the relevant excitation energy range in the $^8$He$+n$ system, performed via a search for the T=5/2 isobaric analog states in $^9$Li populated through $^8$He+p elastic scattering. The present data show no indication of any narrow structures. Instead, we find evidence for a broad $J^{\pi}=1/2^+$ state in $^9$He located approximately 3 MeV above the neutron decay threshold

Testing of a Microwave Blade Tip Clearance Sensor at the NASA Glenn Research Center

The development of new active tip clearance control and structural health monitoring schemes in turbine engines and other types of rotating machinery requires sensors that are highly accurate and can operate in a high temperature environment. The use of a microwave sensor to acquire blade tip clearance and tip timing measurements is being explored at the NASA Glenn Research Center. The microwave blade tip clearance sensor works on principles that are very similar to a short range radar system. The sensor sends a continuous microwave signal towards a target and measures the reflected signal. The phase difference of the reflected signal is directly proportional to the distance between the sensor and the target being measured. This type of sensor is beneficial in that it has the ability to operate at extremely high temperatures and is unaffected by contaminants that may be present in turbine engines. The use of microwave sensors for this application is a new concept. Techniques on calibrating the sensors along with installation effects are not well quantified as they are for other sensor technologies. Developing calibration techniques and evaluating installation effects are essential in using these sensors to make tip clearance and tip timing measurements. As a means of better understanding these issues, the microwave sensors were used on a bench top calibration rig, a large axial vane fan, and a turbofan. Background on the microwave tip clearance sensor, an overview of their calibration, and the results from their use on the axial vane fan and the turbofan will be presented in this paper

Ectopic models for endochondral ossification: comparing pellet and alginate bead culture methods

Key aspects of native endochondral bone development and fracture healing can be mimicked in mesenchymal stem cells (MSCs) through standard in vitro chondrogenic induction. Exploiting this phenomenon has recently emerged as an attractive technique to engineer bone tissue, however, relatively little is known about the best conditions for doing so. The objective of the present study was to compare the bone-forming capacity and angiogenic induction of hypertrophic cell constructs containing human adipose-derived stem cells (hASCs) primed for chondrogenesis in two different culture systems: high-density pellets and alginate bead hydrogels. The hASC constructs were subjected to 4 weeks of identical chondrogenic induction in vitro, encapsulated in an agarose carrier, and then implanted subcutaneously in immune-compromised mice for 8 weeks to evaluate their endochondral potential. At the time of implantation, both pellets and beads expressed aggrecan and type II collagen, as well as alkaline phosphatase (ALP) and type X collagen. Interestingly, ASCs in pellets formed a matrix containing higher glycosaminoglycan and collagen contents than that in beads, and ALP activity per cell was higher in pellets. However, after 8 weeks in vivo, pellets and beads induced an equivalent volume of mineralized tissue and a comparable level of vascularization. Although osteocalcin and osteopontin-positive osteogenic tissue and new vascular growth was found within both types of constructs, all appeared to be better distributed throughout the hydrogel beads. The results of this ectopic model indicate that hydrogel culture may be an attractive alternative to cell pellets for bone tissue engineering via the endochondral pathway

Extreme alpha-clustering in the 18O nucleus

The structure of the 18O nucleus at excitation energies above the alpha decay threshold was studied using 14C+alpha resonance elastic scattering. A number of states with large alpha reduced widths have been observed, indicating that the alpha-cluster degree of freedom plays an important role in this N not equal Z nucleus. However, the alpha-cluster structure of this nucleus is very different from the relatively simple pattern of strong alpha-cluster quasi-rotational bands in the neighboring 16O and 20Ne nuclei. A 0+ state with an alpha reduced width exceeding the single particle limit was identified at an excitation energy of 9.9+/-0.3 MeV. We discuss evidence that states of this kind are common in light nuclei and give possible explanations of this feature.Comment: 4 pages, 2 figures, 1 table. Resubmission with minor changes for clarity, including removal of one figur

Cost-effectiveness analysis of recombinant human follicle-stimulating hormone alfa(r-hFSH) and urinary highly purified menopausal gonadotropin (hMG) based on data from a large German registry

This was a retrospective real-world evidence analysis of the costs per live birth for reference recombinant human follicle-stimulating hormone alfa (r-hFSH-alfa) versus highly purified urinary human menopausal gonadotropin (hMG-HP), based on data from a German in vitro fertilization registry (RecDate). Pregnancy and live birth rates from the RecDate real-world evidence study over three complete assisted reproductive technology (ART) cycles using the same gonadotropin drug were used as clinical inputs. Costs related to ART treatment and to drugs were obtained from public sources. Treatment with r-hFSH-alfa resulted in higher adjusted cumulative live birth rates versus hMG-HP after one (25.3% vs. 22.3%), two (30.9% vs. 27.5%), and three (31.9% vs. 28.6%) ART cycles. Costs per live birth were lower with r-hFSH-alfa versus hMG-HP after one (\u20ac17,938 vs. \u20ac20,054), two (\u20ac18,251 vs. \u20ac20,437), and three (\u20ac18,473 vs. \u20ac20,680) ART cycles. r-hFSH-alfa was found to be a cost-effective strategy compared with hMG-HP over three cycles