The high-pressure behavior of CaMoO4

We report a high-pressure study of tetragonal scheelite-type CaMoO4 up to 29 GPa. In order to characterize its high-pressure behavior, we have combined Raman and optical-absorption measurements with density-functional theory calculations. We have found evidence of a pressure-induced phase transition near 15 GPa. Experiments and calculations agree in assigning the high-pressure phase to a monoclinic fergusonite-type structure. The reported results are consistent with previous powder x-ray-diffraction experiments, but are in contradiction with the conclusions obtained from earlier Raman measurements, which support the existence of more than one phase transition in the pressure range covered by our studies. The observed scheelite-fergusonite transition induces significant changes in the electronic band gap and phonon spectrum of CaMoO4. We have determined the pressure evolution of the band gap for the low- and high-pressure phases as well as the frequencies and pressure dependences of the Raman-active and infrared-active modes. In addition, based upon calculations of the phonon dispersion of the scheelite phase, carried out at a pressure higher than the transition pressure, we propose a possible mechanism for the reported phase transition. Furthermore, from the calculations we determined the pressure dependence of the unit-cell parameters and atomic positions of the different phases and their room-temperature equations of state. These results are compared with previous experiments showing a very good agreement. Finally, information on bond compressibility is reported and correlated with the macroscopic compressibility of CaMoO4. The reported results are of interest for the many technological applications of this oxide.Comment: 36 pages, 10 figures, 8 table

Mixed-Mode Electro-Optical Operation of Ge2Sb2Te5 Nanoscale Crossbar Devices

This is the author accepted manuscript. The final version is freely available from Wiley via the DOI in this record.The use of phase-change materials for a range of exciting new optoelectronic applications from artificial retinas to ultrahigh-resolution displays requires a thorough understanding of how these materials perform under a combination of optical and electrical stimuli. This study reports for the first time the complex link between the electronic and optical properties in real-world crossbar nanoscale devices constructed by confining a thin layer of Ge2Sb2Te5 between transparent indium tin oxide electrodes, forming an optical nanocavity. A novel proof-of-concept device that can be operated by a combination of optical and electrical stimuli is presented, leading the way for the development of further applications based on mixed-mode electro-optical operation.CONACYT. Grant Number: 215365. EPSRC. Grant Numbers: EP/J018783/1, EP/M015173/1, EP/M015130/1, EP/J018694/

Bacteremic Pneumococcal Pneumonia: a Longitudinal Study in 279 Adult Patients from a Single Center

Background: Bacteremic pneumococcal pneumonia (BPP) is the most common clinical presentation of invasive pneumococcal disease (IPD). Although it has been extensively studied, there is little knowledge in our region in relation to burden of disease, demographic and outcome features. Methods: We conducted a prospective, longitudinal, observational study from 1989 to 2015 in adult patients with BPP, in order to deepen our knowledge of the characteristics of this disease in our community hospital in Tandil, Argentina. Results: 279 patients were included. The mean incidence was 2.8/1000 admissions with a sharp decrease in the last two years, reaching 0.8/1000 admissions. Mean patient age was 60 years. Comorbidities were found in 65% of the cases. Non-respiratory symptoms occurred in 50% of cases. Infiltrates on chest x ray were predominantly unilateral (75%) and lobar (57%). Regarding severity, a low PSI score I-II-II was found in 178 patients (64%), 60 (22%) were admitted to ICU, 40 (14%) required mechanical ventilation, and 21 (8%) developed empyema. Penicillin resistance was not found. Mortality was 18% (49/279), and by a multivariate analysis it was associated with confusion (OR= 5.44), age\u3e80 years (OR =5.72), leukopenia (OR =5.73) and dyspnea (OR=7.87). Conclusions: In this study of 279 bacteremic pneumococcal pneumonia we reinforce previous knowledge on this disease regarding incidence and clinical features and confirm a considerable an early mortality associated to age and severity of disease at onset. Recent changes in incidence of BPP in adults could be secondary to herd effect of PVC 13 a vaccine that is mandatory in children in our community since 2012

A nonvolatile phase-change metamaterial color display

This is the final version. Available from Wiley via the DOI in this record.Chalcogenide phase-change materials, which exhibit a marked difference in their electrical and optical properties when in their amorphous and crystalline phases and can be switched between these phases quickly and repeatedly, are traditionally exploited to deliver nonvolatile data storage in the form of rewritable optical disks and electrical phase-change memories. However, exciting new potential applications are now emerging in areas such as integrated phase-change photonics, phase-change optical metamaterials/metasurfaces, and optoelectronic displays. Here, ideas from these last two fields are fused together to deliver a novel concept, namely a switchable phase-change metamaterial/metasurface resonant absorber having nonvolatile color generating capabilities. With the phase-change layer, here GeTe, in the crystalline phase, the resonant absorber can be tuned to selectively absorb the red, green, and blue spectral bands of the visible spectrum, so generating vivid cyan, magenta, and yellow pixels. When the phase-change layer is switched into the amorphous phase, the resonant absorption is suppressed and a flat, pseudowhite reflectance results. Thus, a route to the potential development is opened-up of nonvolatile, phase-change metamaterial color displays and color electronic signage.Engineering and Physical Sciences Research Council (EPSRC

Response: commentary: an in silico- in vitro pipeline identifying an HLA-A*02:01+KRAS G12V+spliced epitope candidate for a broad tumor-immune response in cancer patients

Chemical Immunolog