10 research outputs found

    Implicaciones identitarias en la divulgación del patrimonio cultural a través de Internet: un estudio desde la Teoría del Framing

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    Esta investigación, centrada en el patrimonio de los municipios, procura señalar aquellos elementos culturales que, de manera latente, son reflejo de la identidad colectiva de las localidades a través de la red. Por tanto, se plantea que un sitio web municipal es un dispositivo identitario, construido sobre la base de objetos patrimoniales y sucesos históricos, que categorizan a un grupo social y, al mismo tiempo, lo diferencian de los demás colectivos. El objetivo de este trabajo radica, entonces, en identificar los componentes del patrimonio que acaparan mayor cobertura informativa en los portales de los municipios de España, para luego señalar el enfoque que predomina en cuanto a su caracterización; un encuadre basado en la dialéctica entre lo local y lo global. Para ello, se implementó un análisis de contenido sobre una muestra de 500 sedes web de todo el país. A la vista de los resultados, se puede postular que la identidad patrimonial de España está marcada por un cariz religioso, ya que las manifestaciones que mayor presencia suelen tener son las construcciones eclesiásticas (en el plano de lo tangible), así como los eventos litúrgicos (a nivel intangible).This research study focuses on the heritage of municipalities in an attempt to point out the cultural elements that are, in a latent way, a reflection of a town’s collective identity on the Internet. It is thus posited that a municipal website is a mechanism related to identity, constructed on the foundation of heritage objects and historical events that categorize a social group and, at the same time, differentiate it from other groups. The aim of this study was therefore to locate the heritage components that receive the greatest coverage on Spanish municipal websites, to then point out the approach that predominates in their characterization, a frame based on the dialectics between the local and the global. With this goal in mind, we performed a content analysis of a sample of 500 websites throughout Spain. In light of the results, it can be postulated that heritage identity in Spain has a religious tenor, as the manifestations most presented are usually ecclesiastical constructions (on the tangible plane) and liturgical events (on an intangible level)

    Simple Sequence Repeat Identification and Endocarp Characterization of Olive Tree Accessions in a Tunisian Germplasm Collection

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    8 páginas, 2 figuras, 3 tabvas.Most traditional olive-producing countries possess a diversified genetic patrimony in Olea europaea L. Since the emergence of modern olive growing system, the identification, classification, and conservation of autochthonous olive cultivars is a priority for these countries. In this work, a total of 84 accessions belonging to the "Boughrara"-Sfax olive germplasm collection located in Tunisia have been screened using a powerful set of eight simple sequence repeat markers (SSRs). The study revealed a high genetic variability among the collection and detected a total of 64 alleles. For better management of the mentioned germplasm bank, an improved classification of the entries, including new denominations, has been proposed. In addition, several cases of mislabeling, synonymy, and homonymy have been clarified. Genetic relationships among cultivars have been analyzed showing four major clusters. Finally, a correspondence factor analysis demonstrated that cultivars tend to cluster depending on their main use as oil or table olives. No clear clustering tendencies were observed when the geographical origin of cultivars was used as the criteria for the analysis. All results obtained by SSR screening and classification were in accordance with classification based on morphological traits of fruit endocarps.This research has been supported by FEDER cofunded Projects BFU 2004-00601/BFI, BFU2008- 00629, and Junta de Andalucı´a P06-AGR-01791. Research carried out by M. Fendri was funded by AECID.Peer reviewe

    Use of microsatellite markers for the characterization of Tunisian olive cultivars

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    Resumen del trabajo presentado al Olivebioteq, S2-P9, celebrado en Sfax (Túnez) del 15 al 19 de Diciembre de 2009.Peer reviewe

    Uso de marcadores microsatélites para la identificación varietal y el estudio de las relaciones genéticas en una colección de variedades de olivo de Túnez

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    Trabajo presentado a las II Jornadas Nacionales del Grupo de Olivicultura de la SECH, Sesión I-Material vegetal, celebradas en Tarragona (España) del 2 al 3 de MArzo de 2009.Este trabajo ha sido financiado por los Proyectos BFU 2004-00601/BFI (MEC), BFU2008-00629 (MCI), y P06-AGR-01791 (J. Andalucía).Peer reviewe

    Utilisation de marqueurs microsatellites pour la caractérisation de variétés d'olives tunisiennes

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    Trabajo presentado al Olivebioteq 2009: For a renovated, profitable and competitive Mediterranean olive growing sector, celebrado en Sfax (Túnez) del 15 al 19 de diciembre de 2009.[FR] Dans cette étude, un ensemble de 8 marqueurs microsatellites (SSRs) a été utilisé pour l´analyse de 84 individus appartenant à la banque de germoplasme de “Boughrara”- Sfax. De plus une observation morphologique des endocarpes des fruits a été réalisée afin de confirmer toutes les conclusions obtenues par l´analyse moléculaire. Le contenu en information polymorphique des marqueurs utilisés démontrent leur utilité dans l´identification et la classification des variétés d´olives tunisiennes. Les moyennes d´hétérozigoties et le nombre total d´allèles détectés attestent de la grande variabilité présente dans la collection en question. Cependant, de nombreuses duplications ont été détectées dans cette collection. L´analyse factorielle a permit d´indiquer les tendances d´agroupement entre les génotypes identifiés suivant leurs origines géographiques et l´usage de leurs fruits.[EN] In this work, 84 accessions belonging to “Boughrara”- Sfax germoplasm bank have been screened using a set of 8 selected microsatellite markers (SSRs). Moreover, morphological observation of fruit endocarps has been also performed in order to confirm all conclusions made by the molecular screening. Averages of the polymorphic information content demonstrated that the majority of the utilised markers are very useful for identification and classification of Tunisian olive cultivars. A high variability within the collection was shown by the elevated averages of heterozygosity indexes and the total number of alleles. However, several duplications were detected within the collection. Factorial analysis displayed the cluster tendencies among the identified genotypes using geographical origin and fruit uses as the criteria.Peer reviewe

    Comparación entre Andalucía y Cataluña de la frecuencia de incapacidad laboral durante la gripe (H1N1) 2009

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    Fundamentos: La gripe estacional es una causa frecuente de episodios de incapacidad temporal por contingencia común (ITcc). En este estudio se valora el impacto laboral de la gripe pandémica (H1N1) 2009 en Andalucía y Cataluña durante el periodo 2007- 2009. Métodos: Estudio de series temporales de los casos de ITcc por gripe, según edad y sexo. Se compararon los nuevos casos de ITcc por gripe en un primer periodo epidémico (de 01/01/2007 hasta 30/09/2009) y un segundo periodo pandémico (tres últimos meses de 2009). Se calculó el número semanal de nuevos casos de ITcc por gripe, representándose gráficamente los valores mínimo, mediano y máximo de los casos notificados durante el periodo epidémico y el pandémico. Resultados:Al contrario de lo esperado, las mujeres presentaron 52,2% en Cataluña y 49,7% en Andalucía de nuevos casos de ITcc por gripe durante el periodo pandémico. Durante ambos periodos, el grupo de edad de 25 a 34 años presentó mayor número de casos tanto en Cataluña (37.439 en el periodo epidémico y 15.379 en el pandémico) como en Andalucía (periodo epidémico 20.465 y periodo pandémico 9.630). La llegada de la pandemia se situó alrededor del mes de noviembre (aproximadamente 10.000 casos en Cataluña y 5.000 casos en Andalucía), produciéndose un importante aumento de casos respecto a la mediana del periodo epidémico. Conclusiones: La aparición de la pandemia de gripe produjo un incremento importante de casos de ITcc, algo superior en Cataluña que en Andalucía, adelantándose su acmé a noviembre, especialmente en las mujeres de las dos Comunidades Autónomas

    Efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate in ten countries in Europe and Latin America (HERALD): a randomised, observer-blinded, placebo-controlled, phase 2b/3 trial

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    Background: Additional safe and efficacious vaccines are needed to control the COVID-19 pandemic. We aimed to analyse the efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate. Methods: HERALD is a randomised, observer-blinded, placebo-controlled, phase 2b/3 clinical trial conducted in 47 centres in ten countries in Europe and Latin America. By use of an interactive web response system and stratification by country and age group (18–60 years and ≥61 years), adults with no history of virologically confirmed COVID-19 were randomly assigned (1:1) to receive intramuscularly either two 0·6 mL doses of CVnCoV containing 12 μg of mRNA or two 0·6 mL doses of 0·9% NaCl (placebo) on days 1 and 29. The primary efficacy endpoint was the occurrence of a first episode of virologically confirmed symptomatic COVID-19 of any severity and caused by any strain from 15 days after the second dose. For the primary endpoint, the trial was considered successful if the lower limit of the CI was greater than 30%. Key secondary endpoints were the occurrence of a first episode of virologically confirmed moderate-to-severe COVID-19, severe COVID-19, and COVID-19 of any severity by age group. Primary safety outcomes were solicited local and systemic adverse events within 7 days after each dose and unsolicited adverse events within 28 days after each dose in phase 2b participants, and serious adverse events and adverse events of special interest up to 1 year after the second dose in phase 2b and phase 3 participants. Here, we report data up to June 18, 2021. The study is registered at ClinicalTrials.gov, NCT04652102, and EudraCT, 2020–003998–22, and is ongoing. Findings: Between Dec 11, 2020, and April 12, 2021, 39 680 participants were enrolled and randomly assigned to receive either CVnCoV (n=19 846) or placebo (n=19 834), of whom 19 783 received at least one dose of CVnCoV and 19 746 received at least one dose of placebo. After a mean observation period of 48·2 days (SE 0·2), 83 cases of COVID-19 occurred in the CVnCoV group (n=12 851) in 1735·29 person-years and 145 cases occurred in the placebo group (n=12 211) in 1569·87 person-years, resulting in an overall vaccine efficacy against symptomatic COVID-19 of 48·2% (95·826% CI 31·0–61·4; p=0·016). Vaccine efficacy against moderate-to-severe COVID-19 was 70·7% (95% CI 42·5–86·1; CVnCoV 12 cases in 1735·29 person-years, placebo 37 cases in 1569·87 person-years). In participants aged 18–60 years, vaccine efficacy against symptomatic disease was 52·5% (95% CI 36·2–64·8; CVnCoV 71 cases in 1591·47 person-years, placebo, 136 cases in 1449·23 person-years). Too few cases occurred in participants aged 61 years or older (CVnCoV 12, placebo nine) to allow meaningful assessment of vaccine efficacy. Solicited adverse events, which were mostly systemic, were more common in CVnCoV recipients (1933 [96·5%] of 2003) than in placebo recipients (1344 [67·9%] of 1978), with 542 (27·1%) CVnCoV recipients and 61 (3·1%) placebo recipients reporting grade 3 solicited adverse events. The most frequently reported local reaction after any dose in the CVnCoV group was injection-site pain (1678 [83·6%] of 2007), with 22 grade 3 reactions, and the most frequently reported systematic reactions were fatigue (1603 [80·0%] of 2003) and headache (1541 [76·9%] of 2003). 82 (0·4%) of 19 783 CVnCoV recipients reported 100 serious adverse events and 66 (0·3%) of 19 746 placebo recipients reported 76 serious adverse events. Eight serious adverse events in five CVnCoV recipients and two serious adverse events in two placebo recipients were considered vaccination-related. None of the fatal serious adverse events reported (eight in the CVnCoV group and six in the placebo group) were considered to be related to study vaccination. Adverse events of special interest were reported for 38 (0·2%) participants in the CVnCoV group and 31 (0·2%) participants in the placebo group. These events were considered to be related to the trial vaccine for 14 (<0·1%) participants in the CVnCoV group and for five (<0·1%) participants in the placebo group. Interpretation: CVnCoV was efficacious in the prevention of COVID-19 of any severity and had an acceptable safety profile. Taking into account the changing environment, including the emergence of SARS-CoV-2 variants, and timelines for further development, the decision has been made to cease activities on the CVnCoV candidate and to focus efforts on the development of next-generation vaccine candidates. Funding: German Federal Ministry of Education and Research and CureVac

    Long-term effect of a practice-based intervention (HAPPY AUDIT) aimed at reducing antibiotic prescribing in patients with respiratory tract infections

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