Clinical and epidemiological characterization of a lymphogranuloma venereum outbreak in Madrid, Spain: co-circulation of two variants

AbstractThe lymphogranuloma venereum (LGV) outbreak described in the Netherlands in 2003, increased the interest in the genotyping of Chlamydia trachomatis. Although international surveillance programmes were implemented, these studies slowly decreased in the following years. Now data have revealed a new accumulation of LGV cases in those European countries with extended surveillance programmes. Between March 2009 and November 2011, a study was carried out to detect LGV cases in Madrid. The study was based on screening of C. trachomatis using commercial kits, followed by real-time pmpH-PCR discriminating LGV strains, and finally ompA gene was sequenced for phylogenetic reconstruction. Ninety-four LGV infections were identified. The number of cases increased from 10 to 30 and then to 54 during 2009–2011. Incidence of LGV was strongly associated with men who have sex with men; but in 2011, LGV cases were described in women and heterosexual men. Sixty-nine patients were also human immunodeficiency virus (HIV) positive, with detectable viral loads at the moment of LGV diagnosis, suggesting a high-risk of co-transmission. In fact, in four patients the diagnosis of HIV was simultaneous with LGV infection. The conventional treatment with doxycycline was prescribed in 75 patients, although in three patients the treatment failed. The sequencing of the ompA gene permitted identification of two independent transmission nodes. One constituted by 25 sequences identical to the L2b variant, and a second node including 37 sequences identical to L2. This epidemiological situation characterized by the co-circulation of two LGV variants has not been previously described, reinforcing the need for screening and genotyping of LGV strains

Numerical analysis for design of bioinspired ceramic modular armors for ballistic protections

[EN] The exigent requirements for personal protections in terms of energy absorption and ergonomics have led to increasing interest in bioinspired protections. This work focuses on the numerical analysis of ballistic behavior of different bioinspired geometries under impact loadings. Ceramic armors based on ganoid fish scales (the type exhibited by gars, bichirs and reedfishes), placoid fish scales (characterizing sharks and rays) and armadillo natural protection have been considered. Different impact conditions are studied, including perpendicular and oblique impacts to surface protection, different yaw angle, and multiple impacts. Main conclusion is related to the improved efficiency of modular armors against multiple shots exhibiting more localized damage and crack arrest properties. Moreover, its potential ergonomic is a promising characteristic justifying a deeper study.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work has been carried out within the framework of the research program Juan de la Cierva Incorporacion 2015, and research projects DPI2017-88166-R, and RTC-2015-3887-8 of FEDER program financed by the Ministerio de Economia, Industria y Competitividad of Spain. The support of the Generalitat Valenciana, Programme PROMETEO 2016/007 is also acknowledged.González Albuixech, VF.; Rodríguez-Millán, M.; Ito, T.; Loya, JA.; Miguélez, MH. (2019). Numerical analysis for design of bioinspired ceramic modular armors for ballistic protections. International Journal of Damage Mechanics. 28(6):815-837. https://doi.org/10.1177/1056789518795203S815837286Chen, I. H., Kiang, J. H., Correa, V., Lopez, M. I., Chen, P.-Y., McKittrick, J., & Meyers, M. A. (2011). Armadillo armor: Mechanical testing and micro-structural evaluation. Journal of the Mechanical Behavior of Biomedical Materials, 4(5), 713-722. doi:10.1016/j.jmbbm.2010.12.013Chintapalli, R. K., Mirkhalaf, M., Dastjerdi, A. K., & Barthelat, F. (2014). Fabrication, testing and modeling of a new flexible armor inspired from natural fish scales and osteoderms. Bioinspiration & Biomimetics, 9(3), 036005. doi:10.1088/1748-3182/9/3/036005Deka, L. J., Bartus, S. D., & Vaidya, U. K. (2009). Multi-site impact response of S2-glass/epoxy composite laminates. Composites Science and Technology, 69(6), 725-735. doi:10.1016/j.compscitech.2008.03.002Duro-Royo, J., Zolotovsky, K., Mogas-Soldevila, L., Varshney, S., Oxman, N., Boyce, M. C., & Ortiz, C. (2015). MetaMesh: A hierarchical computational model for design and fabrication of biomimetic armored surfaces. Computer-Aided Design, 60, 14-27. doi:10.1016/j.cad.2014.05.005Flores-Johnson, E. A., Shen, L., Guiamatsia, I., & Nguyen, G. D. (2014). Numerical investigation of the impact behaviour of bioinspired nacre-like aluminium composite plates. Composites Science and Technology, 96, 13-22. doi:10.1016/j.compscitech.2014.03.001Grujicic, M., Pandurangan, B., & Coutris, N. (2011). A Computational Investigation of the Multi-Hit Ballistic-Protection Performance of Laminated Transparent-armor Systems. Journal of Materials Engineering and Performance, 21(6), 837-848. doi:10.1007/s11665-011-0004-3Grunenfelder, L. K., Suksangpanya, N., Salinas, C., Milliron, G., Yaraghi, N., Herrera, S., … Kisailus, D. (2014). Bio-inspired impact-resistant composites. Acta Biomaterialia, 10(9), 3997-4008. doi:10.1016/j.actbio.2014.03.022Klasztorny, M., & Świerczewski, M. (2015). NUMERICAL MODELLING AND VALIDATION OF 12.7 MM FSP IMPACT INTO ALFC SHIELD – ARMOX 500T STEEL PLATE SYSTEM. Journal of KONES. Powertrain and Transport, 19(4), 291-299. doi:10.5604/12314005.1138463Liu, P., Zhu, D., Yao, Y., Wang, J., & Bui, T. Q. (2016). Numerical simulation of ballistic impact behavior of bio-inspired scale-like protection system. Materials & Design, 99, 201-210. doi:10.1016/j.matdes.2016.03.040Morka, A., & Nowak, J. (2015). NUMERICAL ANALYSES OF CERAMIC/METAL BALLISTIC PANELS SUBJECTED TO PROJECTILE IMPACT. Journal of KONES. Powertrain and Transport, 19(4), 465-472. doi:10.5604/12314005.1138618Pandya, K., Kumar, C. V. S., Nair, N., Patil, P., & Naik, N. (2014). Analytical and experimental studies on ballistic impact behavior of 2D woven fabric composites. International Journal of Damage Mechanics, 24(4), 471-511. doi:10.1177/1056789514531440Poniżnik, Z., Nowak, Z., & Basista, M. (2015). Numerical modeling of deformation and fracture of reinforcing fibers in ceramic–metal composites. International Journal of Damage Mechanics, 26(5), 711-734. doi:10.1177/1056789515611945Porter, M. M., Ravikumar, N., Barthelat, F., & Martini, R. (2017). 3D-printing and mechanics of bio-inspired articulated and multi-material structures. Journal of the Mechanical Behavior of Biomedical Materials, 73, 114-126. doi:10.1016/j.jmbbm.2016.12.016Reaugh, J. E., Holt, A. C., Welkins, M. L., Cunningham, B. J., Hord, B. L., & Kusubov, A. S. (1999). Impact studies of five ceramic materials and pyrex. International Journal of Impact Engineering, 23(1), 771-782. doi:10.1016/s0734-743x(99)00121-9Rostamiyan, Y., & Ferasat, A. (2016). High-speed impact and mechanical strength of ZrO2/polycarbonate nanocomposite. International Journal of Damage Mechanics, 26(7), 989-1002. doi:10.1177/1056789516644312Russell, B. P. (2014). Multi-hit ballistic damage characterisation of 304 stainless steel plates with finite elements. Materials & Design, 58, 252-264. doi:10.1016/j.matdes.2014.01.074Serjouei, A., Chi, R., Sridhar, I., & Tan, G. E. B. (2015). Empirical Ballistic Limit Velocity Model for Bi-Layer Ceramic–Metal Armor. International Journal of Protective Structures, 6(3), 509-527. doi:10.1260/2041-4196.6.3.509Shaktivesh, Nair, N., & Naik, N. (2014). Ballistic impact behavior of 2D plain weave fabric targets with multiple layers: Analytical formulation. International Journal of Damage Mechanics, 24(1), 116-150. doi:10.1177/1056789514524074Yang, W., Chen, I. H., Gludovatz, B., Zimmermann, E. A., Ritchie, R. O., & Meyers, M. A. (2012). Natural Flexible Dermal Armor. Advanced Materials, 25(1), 31-48. doi:10.1002/adma.20120271

On the families of orthogonal polynomials associated to the Razavy potential

We show that there are two different families of (weakly) orthogonal polynomials associated to the quasi-exactly solvable Razavy potential V(x)=(\z \cosh 2x-M)^2 (\z>0, $M\in\mathbf N$). One of these families encompasses the four sets of orthogonal polynomials recently found by Khare and Mandal, while the other one is new. These results are extended to the related periodic potential U(x)=-(\z \cos 2x -M)^2, for which we also construct two different families of weakly orthogonal polynomials. We prove that either of these two families yields the ground state (when $M$ is odd) and the lowest lying gaps in the energy spectrum of the latter periodic potential up to and including the $(M-1)^{\rm th}$ gap and having the same parity as $M-1$. Moreover, we show that the algebraic eigenfunctions obtained in this way are the well-known finite solutions of the Whittaker--Hill (or Hill's three-term) periodic differential equation. Thus, the foregoing results provide a Lie-algebraic justification of the fact that the Whittaker--Hill equation (unlike, for instance, Mathieu's equation) admits finite solutions.Comment: Typeset in LaTeX2e using amsmath, amssymb, epic, epsfig, float (24 pages, 1 figure

Carcass bone content in wild rabbits hunted in Andalusia (Spain)

Para caracterizar el contenido de hueso de la canal del conejo de monte ( Oryctolagus cuniculus algirus ) procedente de la ca- za, se analizaron 53 canales encorambradas adquiridas en mercados de abastos de Sevilla (España) con un peso medio de 767,8 g. Las canales encorambradas se desollaron y prepararon para obtener las canales de referencia, que tuvieron un peso medio de 551,2 g, Se realizó el despiece tecnológico propuesto por la World Rabbit Science Association, que rindió un 14,3% de patas delanteras, un 38,0% de patas traseras, un 32,1% de pieza lomo y un 11,4% de caja torácica. El contenido de hueso fue del 16,3% en las patas delanteras, 13,4% en las patas traseras, 9,4% en la pieza lomo, 22,5% en la caja torácica y 13,0% en el conjunto de la canal de referencia. El contenido de hueso de la pata trasera fue un predictor fiable del contenido de hueso de la canal de referencia, pues se obtuvo una R 2 =0,737 (p<0,001). No se encontró dimorfismo sexual en el contenido de hue- so ni correlación entre el peso de la canal y el contenido de hueso de la canal del conejo de monte. En comparación con los valores publicados para razas y líneas de aptitud cárnica a la edad de sacrificio habitual en España, el contenido de hueso de la canal del conejo de monte es moderado.With the aim to characterise the carcass bone content of the wild rabbit (Oryctolagus cuniculus algirus) obtained from hunting, 53 specimens (unskinned, eviscerated rabbits) bought in markets of Seville (Spain) were analysed. The specimens weighed 767.8 g. T he reference carcass, obtained by flaying the specimens, weighed 551.2 g, and after carrying out the technological division accord ing the method proposed by the World Rabbit Science Association, 14.3% of fore leg, 38.0% of hind part, 32.1% of loin, and 11.4% of tho ra- cic cage were obtained. Bone percentage was 16.3% in the fore leg, 13.4% in the hind part, 9.4% in the loin, 22.5% in the thora cic ca- ge, and 13.0 in the reference carcass. Bone percentage of the hind leg gave a reliable prediction of the bone percentage of the carcass, because R 2 =0,737 (p<0,001) was achieved. No sexual dimorphism was found for the bone content, nor correlation between carcass weight and bone content of the carcass of the wild rabbit. When compared to figures published for meat breeds and lines at the usual age of slaughtering in Spain, the bone content of the wild rabbit carcass is moderat

A low-pass filter with automatic frequency tuning for a bluetooth receiver

A third-order Gm-C Chebyshev low-pass filter with high linearity and automatic frequency programmability has been designed. The filter is intended to be used as a channel-select filter for a zero-IF Bluetooth receiver. The frequency tuning scheme is simpler and has more relaxed specifications than conventional ones. The filter bandwidth is 0.5 MHz and the overall scheme dissipates 1.1 mA from a 1.8-V supply. The third-order intermodulation (IM3) distortion of the filter for a 1Vpp two-tone signal centered at 350 kHz is -67dB.Ministerio de Ciencia y Tecnología TEC2007-67460-C03-02

Accelerated aging in ultrathin films of a molecular glass former

We report the thermodynamic measurement of the enthalpy released during the aging of supported films of a molecular glass former, toluene, at temperatures well below the glass transition temperature. By using microfabricated devices with very short equilibration times (below 1 s), we evidence a remarkable variation of the relaxation rate on decreasing film thickness from 100 nm down to a 7 nm thick film. Our results demonstrate that surface atoms are more efficient than bulk atoms in attaining low energy configurations within the potential energy landscape

New Algebraic Quantum Many-body Problems

We develop a systematic procedure for constructing quantum many-body problems whose spectrum can be partially or totally computed by purely algebraic means. The exactly-solvable models include rational and hyperbolic potentials related to root systems, in some cases with an additional external field. The quasi-exactly solvable models can be considered as deformations of the previous ones which share their algebraic character.Comment: LaTeX 2e with amstex package, 36 page