148 research outputs found

    Inclusión digital de las mujeres en las políticas españolas de la sociedad de la información

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    Proyecto I+D "Las mujeres como tejedoras de las redes sociales: estrategias relacionales e inclusión digital" (referencia: EDU2013-45134-P)Nuestro objetivo es desvelar los diferentes tratamientos de la "inclusión digital de las mujeres" en los Planes Estratégicos relacionados con la Sociedad de la Información en España. El lenguaje narrativo de dichos Planes encuadra la realidad en "marcos" que configuran un determinado contenido mediante la selección y preponderancia de ciertos atributos y argumentos concretos. Nuestro análisis se sustenta en el análisis de contenido de tipo cuantitativo y enfoque fenomenográfico interpretando las diversas concepciones de inclusión digital. El estudio analiza un total de nueve Planes Estratégicos: cuatro de ámbito nacional y cinco de carácter autonómico. Los resultados muestran la necesidad de plantear políticas específicas orientadas a la inclusión digital de las mujeres, ya que el contenido de los planes analizados no las visibiliza de forma explícita. Términos como "igualdad" o "mujeres" son escasamente empleados. Los resultados instan también a una revisión de discursos estereotipados en la redacción de los Planes genéricos.Our aim is to reveal the different treatments of "digital inclusion of women" present in the Strategic Plans documents related to the Information Society in Spain. The narrative language of these Plans encloses the reality in "frameworks" that configure a concrete content through the selection and preponderance of certain attributes and specific arguments. Our analysis is based on a mixed methodology: a quantitative content analysis and a phenomenographic focus for the interpretation of the different conceptions of digital inclusion. The study analyzes a total of nine Strategic Plans: four of national scope and five of autonomic character. The results show the need to propose specific policies aimed at the digital inclusion of women, since the content of the analyzed plans does not explicitly make them visible being. Terms like "equality" or "women" are sparsely used. The results also urge a review of stereotyped speeches in the drafting of generic plans

    El boletín de verificación del modelo de área limitada del INM

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    Ponencia presentada en: III Simposio Nacional de Predicción del Instituto Nacional de Meteorología, celebrado en 1996 en MadridSe presenta el boletín de verificación del modelo de área limitada del INM, describiendo en detalle cada una de sus partes así como los índices utilizados. Se incluyen los planes de ampliación para evaluar el LAM frente a las observaciones y para evaluar otros modelos (singularmente el del ECMWF) siguiendo las mismas pautas

    Effect of Azospirillum brasilense coinoculated with Rhizobium on Phaseolus vulgaris flavonoids and Nod factor production under salt stress

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    The effects of salt upon Azospirillum brasilense strain Cd on plant growth, nodulation, flavonoid and lipochitooligosaccharide (LCOs-Nod factor) production, were sequentially followed after 4, 7 and 14 days during a Rhizobium-Phaseolus vulgaris cv. Negro Jamapa interaction, in a hydroponics growth system. Azospirillum brasilense promoted root branching in bean seedling roots and increased secretion of nodgene-inducing flavonoid species, as detected by high-performance liquid chromatography (HPLC). The results also support that A. brasilense allows a longer, more persistent exudation of flavonoids by bean roots. A general positive effect of Azospirillum-Rhizobium coinoculation on the expression of nod-genes by Rhizobium tropici CIAT899 and Rhizobium etli ISP42, and on nodulation factor patterns, was observed in the presence of root exudates. The negative effects obtained under salt stress on nod-gene expression and on Nod factors’ appearance were relieved in coinoculated plants.Fil: Dardanelli, Marta Susana. Universidad de Sevilla; España. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Biología Molecular; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Fernández de Córdoba, Francisco J.. Universidad de Sevilla; EspañaFil: Espuny, M. Rosario. Universidad de Sevilla; EspañaFil: Rodríguez Carvajal, Miguel A.. Universidad de Sevilla; EspañaFil: Soria Díaz, María E.. Universidad de Sevilla; EspañaFil: Gil Serrano, Antonio M.. Universidad de Sevilla; EspañaFil: Okon, Yaacov. The Hebrew University of Jerusalem; IsraelFil: Megías, Manuel. Universidad de Sevilla; Españ

    Macronutrient chloride nutrition modulates psii biochemistry of plants

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    Resumen del póster 0043-A presentado en Plant Biology Europe 2023 (PBE 2023), Jul 2023, Marseille, FranceChloride (Cl–) to typical macronutrient levels to optimize cell elongation and the plant-use efficiency of water, nitrogen and CO2/energy (Colmenero-Flores et al., 2019; Cakmak et al., 2023). Maximal Cl– demand occurs during early vegetative growth, when Cl– limitation determines a strong biomass reduction, a deficiency that could not be compensated by additional NO3– supply. This phenotype was associated with changes in PSII biochemistry, including a reduction of the Electron Transport Rate (ETR). This work aims to determine how Cl– affects chloroplast anatomy and photosynthetic parameters such as ETR, thylakoid proton gradient and non-photochemical quenching (NPQ) during early and late plant growth

    Chemical-proteomics Identify Peroxiredoxin-1 as an Actionable Target in Triple-negative Breast Cancer

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    Triple-negative breast cancer (TNBC) is difficult to treat; therefore, the development of drugs directed against its oncogenic vulnerabilities is a desirable goal. Herein, we report the antitumor effects of CM728, a novel quinone-fused oxazepine, against this malignancy. CM728 potently inhibited TNBC cell viability and decreased the growth of MDA-MB-231-induced orthotopic tumors. Furthermore, CM728 exerted a strong synergistic antiproliferative effect with docetaxel in vitro and this combination was more effective than the individual treatments in vivo. Chemical proteomic approaches revealed that CM728 bound to peroxiredoxin-1 (Prdx1), thereby inducing its oxidation. Molecular docking corroborated these findings. CM728 induced oxidative stress and a multi-signal response, including JNK/p38 MAPK activation and STAT3 inhibition. Interestingly, Prdx1 downregulation mimicked these effects. Finally, CM728 led to DNA damage, cell cycle blockage at the S and G2/M phases, and the activation of caspase-dependent apoptosis. Taken together, our results identify a novel compound with antitumoral properties against TNBC. In addition, we describe the mechanism of action of this drug and provide a rationale for the use of Prdx1 inhibitors, such as CM728, alone or in combination with other drugs, for the treatment of TNBC.This project was supported by Centro Atlántico del Medicamento S.A. (CEAMED), CDTI [IDI-20111517], ACIISI [EATIC2017010006], Universidad de Las Palmas de Gran Canaria, Cabildo Insular de Gran Canaria, Fundación del Instituto Canario de Investigación del Cáncer (FICIC), and Miguel Ángel Rodríguez Cardenes. E. Spínola-Lasso is the recipient of a predoctoral fellowship from the Agencia Canaria de Investigación, Innovación y Sociedad de la Información de la Consejería de Economía, Conocimiento y Empleo y por el Fondo Social Europeo (FSE) Programa Operativo Integrado de Canarias 2014-2020, Eje 3 Tema Prioritario 74 (85%) [TESIS2020010081]. J.C. Montero was funded by the Instituto de Salud Carlos III through the Miguel Servet Program [CP12/03073 and CPII17/00015] and received research support from the same institution [PI15/00684 and PI18/00796]. A. Pandiella received funding from the Ministry of Economy and Competitiveness of Spain [BFU2015-71371-R and PID2020-115605RB-I00], Instituto de Salud Carlos III through CIBERONC, Junta de Castilla y León [CSI146P20], CRIS Cancer Foundation, ACMUMA, UCCTA, ALMOM, and the European Community through the Regional Development Funding Program (FEDER)

    Analysis of tourism in Campania as a tool for the development of high-quality cultural services for sightseers: The “Reale Osservatorio Vesuviano” case history

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    The purpose of this work is to identify the guidelines for the development and diversification of the cultural touristic offer achievable at the Reale Osservatorio Vesuviano (ROV). Founded in 1841, it is the oldest volcano observatory in the world and it has always had the vocation for scientific-naturalistic and formative tourism. The present study investigates the connections between the sociology of tourism and the ROV’s sustainability and competitiveness as a tourist destination. Here it is performed a study of the tourist flow, based on the sociology of tourism and on the correct processing of data sets, distinguishing the ''statistical information on tourism" from "tourism statistics", as such a study is the basis of a proper market strategy in different sectors. Tourism remains, in fact, an important phenomenon in world economy: despite the economic crisis of recent years, international tourist arrivals show a positive development of the trend in all the major sub-areas into which the large international areas are traditionally divided. The principles for a future marketing plan were outlined after collecting all the relevant information. The plan was designed to enhance the overall touristic offer of the ROV, never ceasing to consider the integration of natural- scientific aspects and cultural events to be offered within the observatory itself.Published64-872TM. Divulgazione Scientifica6TM. Poli Museali1VV. AltroN/A or not JC

    Age determination procedures on small and medium pelagic species in Spanish Institute of Oceanography (IEO)

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    This handbook presents a summary of the age estimation procedures used in Spanish Institute of Oceanography (IEO) for some of the main commercial small and medium pelagic species of the Spanish fleet: anchovy (Engraulis encrasicolus), sardine (Sardina pichardus), mackerel (Scomber scombrus), chuck mackerel (Scomber colias), horse mackerel (Trachurus trachurus), Mediterranean horse mackerel (Trachurus mediterraneus) and blue whiting (Micromesistius poutassou). It provides information about the sampling program, otolith extraction and preparation, and the age estimation criteria. A summary of the information related to the age accuracy, validation and corroboration of each species is also presented, as well as that related to the age precision, quality control and verification

    Preliminary results from the ECOCADIZ 2020-07 Spanish acoustic survey (01 – 14 August 2020)

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    The present working document summarises a part of the main results obtained from the Spanish (pelagic ecosystem-) acoustic survey conducted by IEO between 01st and 14th August 2020 in the Portuguese and Spanish shelf waters (20-200 m isobaths) off the Gulf of Cadiz (GoC) onboard the R/V Miguel Oliver. The 21 foreseen acoustic transects were sampled. A total of 26 valid fishing hauls were carried out for echo-trace ground-truthing purposes. Four additional night trawls were conducted to collect anchovy hydrated females (DEPM). This working document only provides abundance and biomass estimates for anchovy, sardine and chub mackerel, which are presented without age structure. The distribution of all the mid-sized and small pelagic fish species susceptible of being acoustically assessed is also shown from the mapping of their back-scattering energies. GoC anchovy acoustic estimates in summer 2020 were of 5153 million fish and 44 877 tones, with the bulk of the population occurring in the Spanish waters. The current biomass estimate becomes in the second historical maximum within the time-series. The estimates of sardine abundance and biomass in summer 2020 were 1923 million fish and 50 721 t, estimates close to the historical average, but lower than the values estimated last year and the most recent maxima reached in 2018. A total of 32 854 t and 448 million fish were estimated for Chub mackerel, estimates similar to the most recent ones and very close to the time-series average
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