Explorando la Implementación de un Laboratorio Remoto de Impresión 3D para la Enseñanza de las TIC

El uso de las Tecnologías de la Información y la Comunicación, incluida la impresión 3D, es esencial en la vida moderna, pero su implementación en escuelas se enfrenta a limitaciones como el tiempo, el desperdicio de material y la accesibilidad. Los laboratorios remotos ofrecen una solución al brindar acceso a diversos recursos, mejorando la experiencia de aprendizaje para estudiantes. Se evaluó un laboratorio de impresión 3D proporcionado por LabsLand en centros de secundaria, utilizando un diseño pre/post test. Los resultados demostraron que el laboratorio remoto ayuda a los alumnos a comprender esta tecnología, especialmente en términos de orientación de impresión. La experiencia de usuario también fue medida y los estudiantes mostraron una gran satisfacción, lo que les ayudó a aprender mejor la tecnología. La integración de estos laboratorios remotos puede potenciar la educación en TIC en las escuelas y superar las limitaciones tradicionales

The Progress Test of the European Hematology Association: A New Tool for Continuous Learning

The European Hematology Curriculum, first launched in 2006, was created by the European Hematology Association (EHA) with the aim of harmonizing hema tology training in Europe. Its goals were to define the different areas hematologists are expected to cover during their training, and to establish the minimum recommended levels of competence that a hematology trainee should attain. EHA's education platform (EHA Campus) offers opportu nities for continuous learning for both trainees and specialists. Content is guided by the European Hematology Curriculum, which provides a structure for individual study and self-assess ment. To complete this organized learning environment, a tool for objective assessment of knowledge during and after specialist training was needed. In the spring of 2020, EHA started offering a progress test: a longitudinal test based on equivalent evalua tions given at fixed intervals, assessing developments in knowl edge. The EHA Progress Test was inspired by an earlier version developed by the Swedish Hematology Association in 2013, which has become widely used by specialist trainees and spe cialists in Sweden. Noticeable pedagogical effects, like targeted study efforts in weak knowledge areas, changes in clinical rota tions, and more have been reported in personal questionnaires

A deep look at the nuclear region of UGC 5101 through high angular resolution mid-IR data with GTC/CanariCam

et al.We present an analysis of the nuclear infrared (IR, 1.6-18 μm) emission of the ultraluminous IR galaxy UGC5101 to derive the properties of its active galactic nucleus (AGN) and its obscuring material. We use new mid-IR high angular resolution (0.3-0.5 arcsec) imaging using the Si-2 filter (λ = 8.7 μm) and 7.5-13 μm spectroscopy taken with CanariCam (CC) on the 10.4 m Gran Telescopio CANARIAS. We also use archival Hubble Space Telescope/NICMOS and Subaru/COMICS imaging and Spitzer/IRS spectroscopy. We estimate the near- and mid-IR unresolved nuclear emission by modelling the imaging data with GALFIT. We decompose the Spitzer/IRS and CC spectra using a power-law component, which represents the emission due to dust heated by the AGN, and a starburst component, both affected by foreground extinction. We model the resulting unresolved near- and mid-IR, and the starburst subtracted CC spectrum with the CLUMPY torus models of Nenkova et al. The derived geometrical properties of the torus, including the large covering factor and the high foreground extinction needed to reproduce the deep 9.7 μm silicate feature, are consistent with the lack of strong AGN signatures in the optical.We derive an AGN bolometric luminosity L ~ 1.9 × 10 erg s that is in good agreement with other estimates in the literature.This work has been partly supported by Mexican CONACyT under research grant CB-2011-01-167291. MMP acknowledges support by the CONACyT PhD fellowship programme. AA-H and AH-C acknowledge financial support from the Spanish Plan Nacional de Astronomía y Astrofísica under grant AYA2012-31447, which is partly funded by the FEDER programme, and the Universidad de Cantabria through the Augusto G. Linares programme. CRA is supported by a Marie Curie Intra European Fellowship within the 7th European Community Framework Programme (PIEF-GA-2012-327934). IG-B ackowledges financial support from the Instituto de Astrofísica de Canarias through Fundacion La Caixa and from the Spanish Ministry of Science and Innovation (MICINN) through project PN AYA2013-47742-c4-2-P (Estallidos).Peer Reviewe

Nuclear 11.3μm PAH emission in local active galactic nuclei

A. Alonso-Herrero et al.We present Gran Telescopio CANARIAS CanariCam 8.7 μm imaging and 7.5-13 μm spectroscopy of six local systems known to host an active galactic nucleus (AGN) and have nuclear star formation. Our main goal is to investigate whether the molecules responsible for the 11.3 μm polycyclic aromatic hydrocarbon (PAH) feature are destroyed in the close vicinity of an AGN. We detect 11.3 μm PAH feature emission in the nuclear regions of the galaxies as well as extended PAH emission over a few hundred parsecs. The equivalent width (EW) of the feature shows a minimum at the nucleus but increases with increasing radial distances, reaching typical star-forming values a few hundred parsecs away from the nucleus. The reduced nuclear EWs are interpreted as due to increased dilution from the AGN continuum rather than destruction of the PAH molecules. We conclude that at least those molecules responsible for the 11.3 μm PAH feature survive in the nuclear environments as close as 10 pc from the AGN and for Seyfert-like AGN luminosities. We propose that material in the dusty tori, nuclear gas discs, and/or host galaxies of AGN is likely to provide the column densities necessary to protect the PAH molecules from the AGN radiation field. © 2014 The Authors Published by Oxford University Press on behalf of the Royal Astronomical Society.AA-H and AH-C are partly funded by the Universidad de Cantabria through the Augusto G. Linares programme. AA-H and AH-C acknowledge financial support from the Spanish Plan Nacional grant AYA2012-31447, AA-H and PE from grant AYA2009-05705-E, CRA from grant AYA2010-21887-C04.4 (Estallidos), PE from grant AYA2012-31277, and LC from grant AYA2012-32295. CRA acknowledges financial support from the Marie Curie Intra European Fellowship within the 7th European Community Framework Programme (PIEF-GA-2012-327934) and SFH from the Marie Curie International Incoming Fellowship within the 7th European Community Framework Programme (PIIFGA-2013-623804).Peer Reviewe

Prognostic stratification of adult primary glioblastoma multiforme patients based on their tumor gene amplification profiles

[EN]everal classification systems have been proposed to address genomic heterogeneity of glioblastoma multiforme, but they either showed limited prognostic value and/or are difficult to implement in routine diagnostics. Here we propose a prognostic stratification model for these primary tumors based on tumor gene amplification profiles, that might be easily implemented in routine diagnostics, and potentially improve the patients management. Gene amplification profiles were prospectively evaluated in 80 primary glioblastoma multiforme tumors using singlenucleotide polymorphism arrays and the results obtained validated in publicly available data from 267/347 cases. Gene amplification was detected in 45% of patients, and chromosome 7p11.2 including the EGFR gene, was the most frequently amplified chromosomal region - either alone (18%) or in combination with amplification of DNA sequences in other chromosomal regions (10% of cases). Other frequently amplified DNA sequences included regions in chromosomes 12q(10%), 4q12(7%) and 1q32.1(4%). Based on their gene amplification profiles, glioblastomas were subdivided into: i) tumors with no gene amplification (55%); ii) tumors with chromosome 7p/EGFR gene amplification (with or without amplification of other chromosomal regions) (38%); and iii) glioblastoma multiforme with a single (11%) or multiple (6%) amplified DNA sequences in chromosomal regions other than chromosome 7p

Black list and Alert list of the Aquatic Invasive Alien Species in the Iberian Peninsula: an action of the LIFE INVASAQUA

Resumen del trabajo presentado en VI Congreso Nacional sobre Especies Exóticas Invasoras y I Congreso Ibérico sobre EEI (EEI 2022) celebrado en Navarra del 20 al 23 de abril de 2022.One of the objectives of LIFE INVASQUA project is to develop tools that will be more efficient the Early Warning and Rapid Response (EWRR) framework for Invasive Alien Species in the Iberian Peninsula. Horizon scanning for high-risk IAS is basic in implementing measures to reduce new invasions, developing Alert lists, and to focus effort in the species already established, for instance making a Black list. We developed a trans national horizon scanning exercise focused on inland waters of Spain and Portugal in order to provide a prioritized lists (Black list and Alert list) of aquatic IAS that may pose a threat to aquatic ecosystems and socio economic sectors in the future. We followed a step approach of existing information about IAS (Plants, Freshwater Invertebrates, Estuarine Invertebrates and Vertebrates; 127 established taxa in Black list; 90 non established taxa in Alert list) combining with an expert scoring of prioritized taxa. IAS established in the Iberian aquatic system consistently highlighted as the worst included vertebrates (e.g. Cyprinus carpio, Gambusia holbrooki, Silurus glanis), freshwater and estuarine invertebrates (e.g. Procambarus clarkii, Dreissena polymorpha, Pacifastacus leniusculus, Ficopomatus enigmaticus, Callinectes sapidus, Corbicula fluminea) and plants (e.g. Eichhornia crassipes, Azolla filiculoides, Ludwigia grandiflora). Amongst taxa not yet established (Alert list), expert pointed to Perna viridis, Hydroides dirampha, Dreissena bugensis, Procambarus fallax f. virginallis, Perccottus glenii with higher risk of invasion, ecological and socioeconomic impacts. Over 20.6% of the taxa in the preliminary black list received no votes (no prioritization) by experts, 17.8% in the innitial alert list. Our horizon scanning approach is inclusive of all-taxa, prioritizes both established and emerging biological threats across trans-national scales, and considers not only the ecological impact, but also potential direct economic consequences as well as the manageability of invasive species.This work received funds from the LIFE Programme (LIFE17 GIE/ES/000515)

Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

A measurement of the cosmic-ray spectrum for energies exceeding $4{\times}10^{18}$ eV is presented, which is based on the analysis of showers with zenith angles greater than $60^{\circ}$ detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above $5.3{\times}10^{18}$ eV, the "ankle", the flux can be described by a power law $E^{-\gamma}$ with index $\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)}$ followed by a smooth suppression region. For the energy ($E_\text{s}$) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find $E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19}$ eV.Comment: Replaced with published version. Added journal reference and DO

Energy Estimation of Cosmic Rays with the Engineering Radio Array of the Pierre Auger Observatory

The Auger Engineering Radio Array (AERA) is part of the Pierre Auger Observatory and is used to detect the radio emission of cosmic-ray air showers. These observations are compared to the data of the surface detector stations of the Observatory, which provide well-calibrated information on the cosmic-ray energies and arrival directions. The response of the radio stations in the 30 to 80 MHz regime has been thoroughly calibrated to enable the reconstruction of the incoming electric field. For the latter, the energy deposit per area is determined from the radio pulses at each observer position and is interpolated using a two-dimensional function that takes into account signal asymmetries due to interference between the geomagnetic and charge-excess emission components. The spatial integral over the signal distribution gives a direct measurement of the energy transferred from the primary cosmic ray into radio emission in the AERA frequency range. We measure 15.8 MeV of radiation energy for a 1 EeV air shower arriving perpendicularly to the geomagnetic field. This radiation energy -- corrected for geometrical effects -- is used as a cosmic-ray energy estimator. Performing an absolute energy calibration against the surface-detector information, we observe that this radio-energy estimator scales quadratically with the cosmic-ray energy as expected for coherent emission. We find an energy resolution of the radio reconstruction of 22% for the data set and 17% for a high-quality subset containing only events with at least five radio stations with signal.Comment: Replaced with published version. Added journal reference and DO