Síntesi de nous complexos de Coure i Ruteni amb lligands de tipus tri-N-dentats: estudi de les seves propietats magnètiques i/o electroquímiques

This doctoral dissertation is divided in two different parts. The first one deals with copper complexes and their magnetic properties. The second one describes the synthesis and characterization of a new family of ruthenium compounds containing polipyridilic ligands and other species such as chloro, oxo or aquo ligandsEl treball recopilat en aquesta tesi es troba dividit en dues seccions. La primera descriu la recerca duta a terme en el camp d’estudis magnètics sobre complexos polinuclears de coure. La segona recull la síntesi i caracterització d’una família de complexos de ruteni contenint el lligand bpea i altres lligands com el clorur, la bipiridina o el lligand aqu

Incorporation of methylene blue into mesoporous silica nanoparticles for singlet oxygen generation

Different strategies to incorporate methylene blue (MB) into silica nanoparticles are described, leading to either its monomeric or dimeric form. The supported photosensitizer displays increased ability to generate 1 O 2 with regard to MB in solution

Carboranycarboxylate Complexes as Efficient Catalysts in Epoxidation Reactions

This work presents the first examples of carboranylcarboxylate complexes as precatalysts in epoxidation reactions with the use of peracetic acid as the oxidant. The manganese [Mn(μ-H2O)(1-CH3-2-CO2-1,2-closo-C2B10H10)2]n·(H2O)n (1), [Mn2(1-CH3-2-CO2-1,2-closo-C2B10H10)4(2,2'-bpy)2] (2, bpy = bipyridine), [Mn(1-CH3-2-CO2-1,2-closo-C2B10H10)2(bpm)]n (3, bpm = bipyrimidine), and [Mn(1-CH3-2-CO2-1,2-closo-C2B10H10)2(2,2'-bpy)2] (4) complexes and the cobalt [Co2(μ-H2O)(1-CH3-2-CO2-1,2-closo-C2B10H10)4(thf)4] (6) complex, all containing the carboranylcarboxylic 1-CH3-2-CO2H-1,2-closo-C2B10H10 (LH) ligand, together with Mn3(OAc)6(2,2'-bpy)2 (5) displayed good performance with high conversions and selectivity values in short reaction times, in most cases. This work highlights that the coordination of the carboranylcarboxylic ligand to the metal ions is crucial to the performance of the complexes as catalystsThis research has been financed by the Spanish Ministerio de Economía y Competitividad (CTQ2015-66143-P; CTQ2016-75150-R) and Generalitat de Catalunya through project 2014-SGR-14

Reusable manganese compounds containing pyrazole-based ligands for olefin epoxidation reactions

We describe the synthesis of new manganese(II) and manganese(III) complexes containing the bidentate ligands 2-(3-pyrazolyl)pyridine, pypz-H, and 3(5)-(2-hydroxyphenyl)pyrazole, HOphpz-H, with formula [MnX2(pypz-H)2] (X = Cl−, 1, CF3SO3−, 2, OAc−, 3 or NO3− (4)), [MnCl2(pypz-H)(H2O)2], 5, or [MnCl- (Ophpz-H)2], 6. All the complexes have been characterized through analytical, spectroscopic and electrochemical techniques. Single X-ray structure analysis revealed a six-coordinated Mn(II) ion in complexes 15, and a five-coordinated Mn(III) ion in complex 6. Compound 5 is the first co-crystal of Mn(II) containing Cl and H2O ligands together with bidentate nitrogen ligands. The catalytic activity of complexes 16 has been tested with regard to the epoxidation of styrene and, in the case of 1, 5 and 6, other alkenes have been epoxidized using peracetic acid as oxidant in different media, among which glycerol, a green solvent never used in epoxidation reactions using peracetic acid as oxidant. The catalysts show moderate to high conversions and selectivities towards the corresponding epoxides. For complexes 1, 5 and 6, a certain degree of cis → trans isomerization is observed in the case of cis-β-methylstyrene. These observations have been explained through computational calculations. The reutilization of catalysts 1 and 6 for the epoxidation of alkenes has been evaluated in [bmim] : acetonitrile mixture (bmim = 1-butyl- 3-methylimidazolium), allowing the effective recyclability of the catalytic system and keeping high conversion and selectivity values up to 12 successive runs, in all casesThis research has been financed by MINECO of Spain through projects, CTQ2010-21532-C02-01 and CTQ2014-54306-P. EM thanks UdG for a predoctoral grant. Serveis Tècnics de Recerca (STR) from UdG are also acknowledged for technical support. AP thanks the Spanish MINECO for project CTQ2014-59832- JIN and European Commission for a Career Integration Grant (CIG09-GA-2011-293900). MS thanks EU for a FEDER fund (UNGI10-4E-801) and the Generalitat de Catalunya for project 2014SGR931 and ICREA Academia 2009 priz

Carving 1D CoII-carboranylcarboxylate system by organic solvents creating stable trinuclear molecular analogous: complete structural and magnetic studies

This work presents a straightforward methodology to achieve small linear trinuclear molecules based on the CoII-carboranylcarboxylate system obtained by carving a 1D polynuclear analogous system with the use of diethylether. The reaction of the carboranylcarboxylic ligand, 1-CH3-2-CO2H-1,2-closo-C2B10H10 (LH) with different cobalt salts leads to the polynuclear compound [Co2(μ-H2O)(1-CH3-2-CO2-1,2-closo- C2B10H10)4(THF)4], 1 and the polymeric [Co(μ-H2O)(1-CH3-2-CO2-1,2-closo-C2B10H10)2]n(H2O)n 2. This latter 1D chain has been obtained by an unprecedented synthetic strategy for the isolation of cobalt(II) compounds.[Co3(μ-H2O)2(1-CH3-2-CO2-1,2-closo-C2B10H10)6(H2O)2(C4H10O)2], 3 is formed by the dissociation of the polymeric structure that forms 2 when a mild coordinating solvent such as diethylether is added. These compounds have been characterized by analytical and spectroscopic techniques. X-ray analysis of 1 and 3 revealed that 1 presents a dinuclear structure whereas 3 is trinuclear; in both cases a six-coordinated CoII compound with water molecules bridging each of the two CoII centres has been observed. The magnetic properties of 1 and 3 show a weak antiferromagnetic behaviour, respectively, between the CoII centres mediated by two carboxylate ligands and a molecule of wate

El Treball autònom: eina de reflexió en el marc de les assignatures de grau

En diferents assignatures de primer de grau, s’han planificat activitats d’aprenentatge que tenen com a finalitat fer reflexionar a l’estudiant sobre com aprèn a partir d’un conjunt de preguntes relacionades amb: com es planifiquen, com fan el seguiment o la regulació de la posada en pràctica d’allò que han planificat i com avaluen al final els resultats aconseguits. I, a més, que siguin capaços d’aplicar aquest esquema d’actuació en qualsevol de les activitats d’aprenentatge que se’ls plantegi (activitats de laboratori, exercicis de classe, activitats de sortida de camp, exàmens, ...). En realitat, es tracta d’aconseguir responsabilitzar l’estudiant del seu aprenentatge, requeriment imprescindible per a la seva autonomi

A family of manganese complexes containing heterocyclic-based ligands with cytotoxic properties

We describe the synthesis of three new manganese (II) complexes containing the bidentate ligands 2-(1-methyl-3-pyrazolyl)pyridine (pypz-Me) and ethyl 2-(3-(pyridine-2-yl)-1H–pyrazol-1-yl)acetate (pypz-CH2COOEt), with formula [MnX2(pypz-Me)2] (X = Cl−1, CF3SO3−2) and [Mn(CF3SO3)2(pypz-CH2COOEt)2] 3. Complexes 1–3 have been characterized through analytical, spectroscopic and electrochemical techniques, as well as by monocrystal X-ray diffraction analysis. The complexes show a six-coordinated Mn(II) ion though different stereoisomers have been isolated for the three compounds. Complexes 1–3, together with the previously described compounds [MnCl2(pypz-H)2] 4, [Mn(CF3SO3)2(pypz-H)2] 5, [Mn(NO3)2(pypz-H)2] 6, [MnCl2(H2O)2(pypz-H)2] 7 (pypz-H = 2-(3-pyrazolyl)pyridine) and ([Mn(CF3SO3)2((−)-L)2] 8, ((−)-L = (−)-pinene[5,6]bipyridine), were tested in vitro for cytotoxic activity against NCI-H460 and OVCAR-8 cancer cell lines. The geometry of a specific compound does not seem to influence its activity in a significant extent. However, among the tested compounds those that display hydrophobic substituents on the pyrazole ring and triflate ions as labile ligands show the best antiproliferative properties. Specifically, compound 8 containing the pinene-bipyridine ligand presents an antiproliferative activity similar to that of cisplatin and higher than that of carboplatin, and displays selectivity for tumour cells. Its antiproliferative effect is due to the generation of ROS species that allow the compound to interact with DNAThis research has been financed by Ministerio de Economia y Competitividad (MINECO) Spain, through projects CTQ2015-66143-P and BIO2013-43517, by Universitat de Girona through projects MPCUdG2016-18 and MPCUdG2016/048 and by DGU, Generalitat de Catalunya through projects SGR2014-70 and SGR2014-14

Leyendo hasta el confín a lomos del flaco rocín, pero algo despacito que se nos cansa el pollino

El trabajo obtuvo un Premio Tomás García Verdejo a las buenas prácticas educativas en la Comunidad Autónoma de Extremadura para el curso académico 2015/2016. Modalidad BCon motivo de la celebración del 400 aniversario de la edición de la segunda parte de El Quijote (1615-2015) y del cuarto centenario de la muerte de Cervantes (1616-2016) se llevó a cabo en el IES Enrique Díez Canedo de Puebla de la Calzada (Badajoz) un proyecto que pretendía dar a conocer a la comunidad educativa la figura literaria y humana de Miguel de Cervantes, más allá del saber popular de El Quijote. Para ello se realizaron diferentes actividades, entre otras: la creación, a partir de alguna parte de El Quijote, de textos, dibujos, o figuras; lectura de partes de la obra; uso de la biblioteca escolar; difusión de las actividades a través del blog de la biblioteca o de la revista del centro; representación de obras de teatro alusivas a la obra, etc.ExtremaduraES

Tu salud la cuidas tú, y nosotros te ayudamos

El trabajo obtuvo el primer premio de la modalidad B: 'Una escuela más cooperativa y equitativa', de los Premios Joaquín Sama 2007. Se recogen páginas web de interés sobre la temática del trabajoSe describen un conjunto de actividades desarrolladas en el IES Siberia Extremeña (Talarrubias, Badajoz) para concienciar a los alumnos y a la comunidad educativa sobre los efectos nocivos del tabaco, el alcohol y otras drogas.ExtremaduraConsejería de Educación. Dirección General de Política Educativa; Calle Delgado Valencia, 6; 06800 Mérida (Badajoz); Tel. +34924006714; Fax +34924006716; [email protected]

Nosotras

El trabajo obtuvo un Premio Tomás García Verdejo a las buenas prácticas educativas en la Comunidad Autónoma de Extremadura para el curso 2017/2018. Modalidad BDesde la creación del IES Enrique Díez Canedo de Puebla de la Calzada (Badajoz) en 1995, se ha hecho un importante esfuerzo, a parte de en la transmisión de conocimientos, en la educación en valores que contribuyan a formar personas justas, rigurosas y respetuosas que sepan valorar a los demás independientemente de su condición social o de género. Con la educación en valores como piedra angular, a lo largo del curso académico 2017-2018 se desarrollaron actividades que tenían como objetivo contribuir a hacer a la mujer co-protagonista de la historia y la educación, dándole visibilidad en campos del conocimiento que habitualmente las ha mantenido en un segundo planoExtremaduraES