12 research outputs found
Actinic Cheilitis prevalence and risk factors: a cross-sectional, multicentre study in a population aged 45 years and over in north-west Spain
Actinic cheilitis is thought to be a premalignant lesion or a superficial squamous cell carcinoma. The prevalence of actinic cheilitis in Europe is unknown. The aim of this study was to determine the prevalence of actinic cheilitis in the Galicia region (north-west Spain). Secondary objectives were the description of risk factors of actinic cheilitis. A cross-sectional multicentre study in patients ≥ 45 years of age was performed in 8 dermatology departments in Galicia region during a 1-year period. The prevalence of actinic cheilitis was 31.3%. Significant and independent risk factors of actinic cheilitis after multivariate analysis were age ≥ 60 years, Fitzpatrick skin phototype II, outdoor working for more than 25 years, and previous history of non-melanoma skin cancer. This is the first cross-sectional multicentre study of the prevalence of actinic cheilitis in Europe. Actinic cheilitis was present in almost one-third of the screened patients. Lip examination should be performed in all patients with chronic actinic damageS
Actinic cheilitis: analysis of clinical subtypes, risk factors and associated signs of actinic damage
Actinic cheilitis (AC) is a common condition that mainly
involves the lower lip, which is associated with chronic
exposure to ultraviolet (UV) radiation. AC is considered
a precursor of malignancy (1), but the rate of progression
from AC to invasive squamous cell carcinoma (SCC)
has not yet been established. An epidemiological study
previously described the prevalence of AC and its associated variables in the Galicia region (north-western
Spain); the prevalence of AC in a population aged 45
years and over was 31.3%, and multivariate analysis
showed that significant and independent risk factors for
AC were age ≥60 years, Fitzpatrick skin phototypes I
and II, working outdoors for more than 25 years, and a
history of non-melanoma skin cancer (NMSC) (2). We
report here a subanalysis of the clinical manifestations
of AC and the associations of AC with other markers of
actinic damageS