3,338 research outputs found

    Gamow-Teller strength distributions for double-beta-decaying nuclei within continuum-QRPA

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    A version of the pn-continuum-QRPA is outlined and applied to describe the Gamow-Teller strength distributions for ββ\beta\beta-decaying open-shell nuclei. The calculation results obtained for the pairs of nuclei 116^{116}Cd-Sn and 130^{130}Te-Xe are compared with available experimental data.Comment: 8 pages, 3 figures, To appear in the proceedings of "Nucleus-2007: Fundamental problems of nuclear physics, atomic power engineering and nuclear technologies" Voronezh, Russia, June 25-29, 200

    Seasonal Water "Pump" in the Atmosphere of Mars: Vertical Transport to the Thermosphere

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    We present results of simulations with the Max Planck Institute general circulation model (MPI-MGCM) implementing a hydrological cycle scheme. The simulations reveal a seasonal water "pump" mechanism responsible for the upward transport of water vapor. This mechanism occurs in high latitudes above 60∘^\circ of the southern hemisphere at perihelion, when the upward branch of the meridional circulation is particularly strong. A combination of the mean vertical flux with variations induced by solar tides facilitates penetration of water across the "bottleneck" at approximately 60 km. The meridional circulation then transports water across the globe to the northern hemisphere. Since the intensity of the meridional cell is tightly controlled by airborne dust, the water abundance in the thermosphere strongly increases during dust storms.Comment: 15 pages, 4 figure

    Phosphorene nanoribbons

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    Edge-induced gap states in finite phosphorene layers are examined using analytical models and density functional theory. The nature of such gap states depends on the direction of the cut. Armchair nanoribbons are insulating, whereas nanoribbons cut in the perpendicular direction (with zigzag and cliff-type edges) are metallic, unless they undergo a reconstruction or distortion with cell doubling, which opens a gap. All stable nanoribbons with unsaturated edges have gap states that can be removed by hydrogen passivation. Armchair nanoribbon edge states decay exponentially with the distance to the edge and can be described by a nearly-free electron model

    On origin of genetic code and tRNA before translation

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    Go to: Background Synthesis of proteins is based on the genetic code - a nearly universal assignment of codons to amino acids (aas). A major challenge to the understanding of the origins of this assignment is the archetypal "key-lock vs. frozen accident" dilemma. Here we re-examine this dilemma in light of 1) the fundamental veto on "foresight evolution", 2) modular structures of tRNAs and aminoacyl-tRNA synthetases, and 3) the updated library of aa-binding sites in RNA aptamers successfully selected in vitro for eight amino acids. Go to: Results The aa-binding sites of arginine, isoleucine and tyrosine contain both their cognate triplets, anticodons and codons. We have noticed that these cases might be associated with palindrome-dinucleotides. For example, one-base shift to the left brings arginine codons CGN, with CG at 1-2 positions, to the respective anticodons NCG, with CG at 2-3 positions. Formally, the concomitant presence of codons and anticodons is also expected in the reverse situation, with codons containing palindrome-dinucleotides at their 2-3 positions, and anticodons exhibiting them at 1-2 positions. A closer analysis reveals that, surprisingly, RNA binding sites for Arg, Ile and Tyr "prefer" (exactly as in the actual genetic code) the anticodon(2-3)/codon(1-2) tetramers to their anticodon(1-2)/codon(2-3) counterparts, despite the seemingly perfect symmetry of the latter. However, since in vitro selection of aa-specific RNA aptamers apparently had nothing to do with translation, this striking preference provides a new strong support to the notion of the genetic code emerging before translation, in response to catalytic (and possibly other) needs of ancient RNA life. Consistently with the pre-translation origin of the code, we propose here a new model of tRNA origin by the gradual, Fibonacci process-like, elongation of a tRNA molecule from a primordial coding triplet and 5'DCCA3' quadruplet (D is a base-determinator) to the eventual 76 base-long cloverleaf-shaped molecule. Go to: Conclusion Taken together, our findings necessarily imply that primordial tRNAs, tRNA aminoacylating ribozymes, and (later) the translation machinery in general have been co-evolving to ''fit'' the (likely already defined) genetic code, rather than the opposite way around. Coding triplets in this primal pre-translational code were likely similar to the anticodons, with second and third nucleotides being more important than the less specific first one. Later, when the code was expanding in co-evolution with the translation apparatus, the importance of 2-3 nucleotides of coding triplets "transferred" to the 1-2 nucleotides of their complements, thus distinguishing anticodons from codons. This evolutionary primacy of anticodons in genetic coding makes the hypothesis of primal stereo-chemical affinity between amino acids and cognate triplets, the hypothesis of coding coenzyme handles for amino acids, the hypothesis of tRNA-like genomic 3' tags suggesting that tRNAs originated in replication, and the hypothesis of ancient ribozymes-mediated operational code of tRNA aminoacylation not mutually contradicting but rather co-existing in harmony

    One ancestor for two codes viewed from the perspective of two complementary modes of tRNA aminoacylation

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    <p>Abstract</p> <p>Background</p> <p>The genetic code is brought into action by 20 aminoacyl-tRNA synthetases. These enzymes are evenly divided into two classes (I and II) that recognize tRNAs from the minor and major groove sides of the acceptor stem, respectively. We have reported recently that: (1) ribozymic precursors of the synthetases seem to have used the same two sterically mirror modes of tRNA recognition, (2) having these two modes might have helped in preventing erroneous aminoacylation of ancestral tRNAs with complementary anticodons, yet (3) the risk of confusion for the presumably earliest pairs of complementarily encoded amino acids had little to do with anticodons. Accordingly, in this communication we focus on the acceptor stem.</p> <p>Results</p> <p>Our main result is the emergence of a palindrome structure for the acceptor stem's common ancestor, reconstructed from the phylogenetic trees of Bacteria, Archaea and Eukarya. In parallel, for pairs of ancestral tRNAs with complementary anticodons, we present updated evidence of concerted complementarity of the second bases in the acceptor stems. These two results suggest that the first pairs of "complementary" amino acids that were engaged in primordial coding, such as Gly and Ala, could have avoided erroneous aminoacylation if and only if the acceptor stems of their adaptors were recognized from the same, major groove, side. The class II protein synthetases then inherited this "primary preference" from isofunctional ribozymes.</p> <p>Conclusion</p> <p>Taken together, our results support the hypothesis that the genetic code <it>per se </it>(the one associated with the anticodons) and the operational code of aminoacylation (associated with the acceptor) diverged from a common ancestor that probably began developing before translation. The primordial advantage of linking some amino acids (most likely glycine and alanine) to the ancestral acceptor stem may have been selective retention in a protocell surrounded by a leaky membrane for use in nucleotide and coenzyme synthesis. Such acceptor stems (as cofactors) thus transferred amino acids as groups for biosynthesis. Later, with the advent of an anticodon loop, some amino acids (such as aspartic acid, histidine, arginine) assumed a catalytic role while bound to such extended adaptors, in line with the original coding coenzyme handle (CCH) hypothesis.</p> <p>Reviewers</p> <p>This article was reviewed by Rob Knight, Juergen Brosius and Anthony Poole.</p

    Factors That Contribute to Resiliency in Anishinabe/Ojibwe Children Overcoming Adversity

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    The object of this research is to examine the resilience of the Native Americans from the Mille Lacs Band of Ojibwe. This group of people have faced many forms of adversity over the generations. These adversities include poverty, racism, and cultural separation just to name a few. From the perspective of ecological systems theory, family systems theory, and the strengths perspective, this study focuses on individuals that grew uP on the Mille Lacs reservation and have been recognized as being successful by their tribal community. Reflecting on their childhood, these individuals discussed three factors that contributed to their resiliency. These factors are their family relationships, the supports received from outside their family system, and a belief in self. Identifying these factors and enhancing them in others may benefit the future of individuals, families, and society
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