138 research outputs found

    Providing real-time assistance in disaster relief by leveraging crowdsourcing power

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    Crowdsourcing platforms for disaster management have drawn a lot of attention in recent years due to their efficiency in disaster relief tasks, especially for disaster data collection and analysis. Although the on-site rescue staff can largely benefit from these crowdsourcing data, due to the rapidly evolving situation at the disaster site, they usually encounter various difficulties and have requests, which need to be resolved in a short time. In this paper, aiming at efficiently harnessing crowdsourcing power to provide those on-site rescue staff with real-time remote assistance, we design and develop a crowdsourcing disaster support platform by considering three unique features, viz., selecting and notifying relevant off-site users for individual request according to their expertise; providing collaborative working functionalities to off-site users; improving answer credibility via “crowd voting.” To evaluate the platform, we conducted a series of experiments with three-round user trials and also a System Usability Scale survey after each trial. The results show that the platform can effectively support on-site rescue staff by leveraging crowdsourcing power and achieve good usability

    Early results and lessons learned from a multicenter, randomized, double-blind trial of bone marrow aspirate concentrate in critical limb ischemia

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    ObjectivesDespite advances in endovascular therapies, critical limb ischemia (CLI) continues to be associated with high morbidity and mortality. Patients without direct revascularization options have the worst outcomes. We sought to explore the feasibility of conducting a definitive trial of a bone marrow-derived cellular therapy for CLI in this “no option” population.MethodsA pilot, multicenter, prospective, randomized, double-blind, placebo-controlled trial for “no option” CLI patients was performed. The therapy consisted of bone marrow aspirate concentrate (BMAC), prepared using a point of service centrifugation technique and injected percutaneously in 40 injections to the affected limb. Patients were randomized to BMAC or sham injections (dilute blood). We are reporting the 12-week data.ResultsForty-eight patients were enrolled. The mean age was 69.5 years (range, 42-93 years). Males predominated (68%). Diabetes was present in 50%. Tissue loss (Rutherford 5) was present in 30 patients (62.5%), and 18 (37.5%) had rest pain without tissue loss (Rutherford 4). Patients were deemed unsuitable for conventional revascularization based on multiple prior failed revascularization efforts (24 [50%]), poor distal targets (43 [89.6%]), and medical risk (six [12.5%]). Thirty-four patients were treated with BMAC and 14 with sham injections. There were no adverse events attributed to the injections. Renal function was not affected. Effective blinding was confirmed; blinding index of 61% to 85%. Subjective and objective outcome measures were effectively obtained with the exception of treadmill walking times, which could only be obtained at baseline and follow-up in 15 of 48 subjects. This pilot study was not powered to demonstrate statistical significance but did demonstrate favorable trends for BMAC versus control in major amputations (17.6% vs 28.6%), improved pain (44% vs 25%), improved ankle brachial index (ABI; 32.4% vs 7.1%), improved Rutherford classification (35.3% vs 14.3%), and quality-of-life scoring better for BMAC in six of eight domains.ConclusionsIn this multicenter, randomized, double-blind, placebo-controlled trial of autologous bone marrow cell therapy for CLI, the therapy was well tolerated without significant adverse events. The BMAC group demonstrated trends toward improvement in amputation, pain, quality of life, Rutherford classification, and ABI when compared with controls. This pilot allowed us to identify several areas for improvement for future trials and CLI studies. These recommendations include elimination of treadmill testing, stratification by Rutherford class, and more liberal inclusion of patients with renal insufficiency. Our strongest recommendation is that CLI studies that include Rutherford 4 patients should incorporate a composite endpoint reflecting pain and quality of life

    Large Scale Research Project, Daidalos Evaluation Framework

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    For large scale research projects operational over a phased timeframe of 2 years or more, the need to take a step back and evaluate their stance and direction is an important activity in providing relevant feedback and recommendations to guide the project towards success in its consecutive phase. The identification of measurable goals and evaluation profile procedures to effectively work towards a useful evaluation of the project was one of the main aims of the Evaluation taskforce. As part of the scope of the evaluation work in Daidalos, a set of evaluation criteria for Daidalos phase I processes, results and impact were determined and used as a scoreboard for the evaluation and recommendation report. Evaluating criterion such as Relevance, Potential Impact, Scientific & Technical Excellence and Resource Mobilisation provided beneficial recommendations, taking stock of previous achievements and future innovative ideas ensuring that they will impact the project as planned. As a starting point these criteria were derived from the ones used by European Commission for evaluating R&D projects. The final evaluation report included the scoreboard results, and an analysis of these results along with a set of recommendations for Daidalos Phase II. Qualitative scenario evaluation activities were adopted and implemented in an attempt to capture the richness of people's experience of the Nidaros scenario in their own terms, conveying the Daidalos technology concept transfer towards end users. By providing you with an insight into the evaluation methodology used within the Daidalos project, we hope to broaden your knowledge by introducing you to the large scale Daidalos evaluation framework used by the Daidalos research project and highlight some of the managerial and organisational aspects involved during this process

    Daidalos Framework for Successful Testbed Integration

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    Daidalos Testbed integration framework required detailed planning and implementation, constantly adapting to the demanding changes of a research project as it advances from development phase to integration phase. This paper describes the various integration and validaton efforts required to deploy an operational Daidalos Testbed infrastructure, demonstrating the effort required to achieve a successful overall integration process. With such a large scale project as Daidalos with a consortium of 49 partners, the Testbed deployment, operation and management was indeed an immense task having to create and enforce Testbed processes suitable for the efficient and effective operation of the Daidalos system during integration and validation

    Using Co-Inquiry to Study Co-Inquiry: Community-University Perspectives on Research

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    In the context of a rapid development of interest in community-university research partnerships, this article argues for a greater focus on collaborative reflexivity to enhance learning from the research process and contribute toward developing sustainable and ethical research collaborations. Incorporating perspectives of community and university participants, the article offers a case study analysis of a UK-based co-inquiry action research group. This group not only studied examples of community-university research collaborations, but also reflected on its own workings as an example of collaborative research in action—scrutinizing relationships of power, responsibility, and boundaries in the group (collaborative reflexivity). This article argues that research projects might be designed with space designated for co-inquiry action research or similar inquiry groups. These co-inquiry groups would serve as replacements or supplements to more traditional steering or advisory groups

    Using co-inquiry to study co-inquiry: community-university perspectives on research collaboration

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    In the context of a rapid development of interest in community-university research partnerships, this article argues for a greater focus on collaborative reflexivity to enhance learning from the research process and contribute toward developing sustainable and ethical research collaborations. Incorporating perspectives of community and university participants, the article offers a case study analysis of a UK-based co-inquiry action research group. This group not only studied examples of community-university research collaborations, but also reflected on its own workings as an example of collaborative research in action—scrutinizing relationships of power, responsibility, and boundaries in the group (collaborative reflexivity). This article argues that research projects might be designed with space designated for co-inquiry action research or similar inquiry groups. These co-inquiry groups would serve as replacements or supplements to more traditional steering or advisory groups

    Large scale interoperability, integrating the Daidalos project

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    This paper discusses the challenges of large scale integration within the context of the massive collaborative mobile & wireless systems beyond 3G research project Daidalos. It first examines the relationship of the Daidalos architecture. It then identifies an integration model that was used for the project, with an overview of the testing processes, tools, and methodologies employed. Next, discusses the Daidalos demonstration scenario, and shows how it was used in the integration execution validation and verification activity of the project. The article closes with a discussion of the research necessary to develop these capabilities further

    Scintillation Observations and Response of The Ionosphere to Electrodynamics (SORTIE) Mission First Light

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    At low and middle latitudes, wave-like plasma perturbations are thought to provide the seeds for larger perturbations that may evolve non-linearly to produce irregularities, which in turn have deleterious effects on HF communications and global positioning systems. Unfortunately, there is currently no comprehensive atlas of measurements describing the global spatial or temporal distribution of wave-like perturbations in the ionosphere. The SORTIE mission, a CubeSat experiment with team members from ASTRA, AFRL, UTD, and Boston College, was designed to help map and further understand the wave-like plasma perturbation distributions throughout the ionosphere. The SORTIE 6U CubeSat sensor package measures key in-situ plasma parameters, and includes an ion velocity meter and a planar Langmuir probe. SORTIE will provide (1) the initial spectrum of wave perturbations which are the starting point for plasma instabilities; (2) measured electric fields which determine the magnitude of the instability growth rate near the region where plasma bubbles are generated; (3) initial observations of irregularities in plasma density which result from plasma instability growth. The SORTIE spacecraft was deployed from the ISS in February 2020 and began data collections shortly after orbit insertion. The measurements are expected to continue for at least a year. In this presentation we present the first light results of the SORTIE mission, as well as reviewing the science objectives and providing an overview of the spacecraft and instruments
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