Awaiting the support of the written description: defining the technical contribution in the emergence of early English patent law

PhDTechnology had made but tentative advances under the aegis of oral communication with merely sporadic demands for a recognisably modern patent system until the late 1700s. Fixity of craft knowledge had a problematic upbringing with guilds propagating stasis under a collectivist encirclement of skills. Emancipation from this feudalistic overhang was associated with mysteries often not tethered to a location; untied by sole-trading sometimes immigrant artisans including apothecaries, applied mathematicians and surgical practitioners, with the use of notebooks to question, record, and faithfully witness explanation and clinical experiences. These vernacular descriptions revealed an inheritable imperative to forego secrecy. Meanwhile, government attempts to administer the phenomenon of invention becoming a democratic asset required that the introducer, as well as the originator, be rewarded. The highly-skilled responded to this security, London’s allure creating a polyglot conurbation, yet one where the utility of early formats of inventive output required but vague commitments to public education. Having finally exposed the inadequacies of oral information-transfer, the parallels of the advent of printing presses and the reach of faith, stimulated access to learned communications. Later, scientific literacy created a new appreciation of vulgar knowledge; this elevation also uncovering novel entrepreneurial chattels; individual property in everyday techniques. The jigsaw next required key visionaries: those who were technologically adept while simultaneously demanding written instruments to stipulate inventive space. The reaction of the Commons was to legislate against monopolies, a response insufficient to foster patents for invention. The mosaic of language initiated a still later seismic shift in the description of scientific phenomena. Publication became the arc of progress through which new fraternities held sway as intellectual networks demanded the utensil of the hypothesis to interpret advances. Contemporaneously, the early adoption of some broad patents provided a realisation whereby, discriminating that which was truly momentous required disclosure of a full written description, the most significant part of which was to become the applicant’s patent specification.Staff Development Fund of Athlone Institute of Technology, Athlone, Irelan

The Mid-Infrared Emission of M87

We discuss Subaru and Spitzer Space Telescope imaging and spectroscopy of M87 in the mid-infrared from 5-35 um. These observations allow us to investigate mid-IR emission mechanisms in the core of M87 and to establish that the flaring, variable jet component HST-1 is not a major contributor to the mid-IR flux. The Spitzer data include a high signal-to-noise 15-35 $\mu$m spectrum of the knot A/B complex in the jet, which is consistent with synchrotron emission. However, a synchrotron model cannot account for the observed {\it nuclear} spectrum, even when contributions from the jet, necessary due to the degrading of resolution with wavelength, are included. The Spitzer data show a clear excess in the spectrum of the nucleus at wavelengths longer than 25 um, which we model as thermal emission from cool dust at a characteristic temperature of 55 \pm 10 K, with an IR luminosity \sim 10^{39} {\rm ~erg ~s^{-1}}. Given Spitzer's few-arcsecond angular resolution, the dust seen in the nuclear spectrum could be located anywhere within ~5'' (390 pc) of the nucleus. In any case, the ratio of AGN thermal to bolometric luminosity indicates that M87 does not contain the IR-bright torus that classical unified AGN schemes invoke. However, this result is consistent with theoretical predictions for low-luminosity AGNsComment: 9 pages, 7 figures, ApJ, in pres

Analysis of Bio-Obtainable Endocrine Disrupting Metals in River Water and Sediment, Sewage Influent/Effluent, Sludge, Leachate, and Concentrated Leachate, in the Irish Midlands Shannon Catchment

The application of an acid digestion and subsequent solid-phase extraction (SPE) procedure were implemented as preliminary treatments prior to quantifying the levels of potentially endocrine disrupting metals (EDMs) in a variety of solid and liquid matrices. These included (solid) river sediment, leachate sediment and sewage sludge and also (liquid) river water, landfill leachate, concentrated leachate, sewage influent, and sewage effluent, sampled in the Irish Midlands. The total concentrations of cobalt (Co), cadmium (Cd), copper (Cu), chromium (Cr), nickel (Ni), lead (Pb), zinc (Zn), and manganese (Mn), after extraction and preconcentration, were determined by atomic absorption spectroscopy (AAS). Mercury (Hg) in sediment and sludge was determined using cold-vapour atomic fluorescence spectroscopy (AFS). For sewage sludge maximum values (mg/kgdw) of 4700 Ni, 1642 Mn, 100.0 Cd, 3400 Zn, 36.70 Co, 750.0 Pb, 485.8 Cr, and 1003 Cu were determined whilst in leachate sediment, maximum values (mg/kgdw) of 32.10 Ni, 815.0 Mn, 32.78 Cd, 230.3 Zn, 26.73 Co, 3525 Pb, 124.9 Cr, and 50.13 Cu were found. Over several months, the data showed elevated levels in sewage influents, effluents, and sludges compared to a battery of adjacent river water samples and corresponding sediments. There was a definite trend for target values for sediments to be exceeded, while intervention values were only exceeded for cadmium. Overall the pattern in terms of concentration was sewage > leachate > river matrices. A nonparametric assessment of the effect of sewage treatment method on median metal levels in sludge revealed statistically significant differences at the 95% level of confidence for Co, Cr, and Hg and at the 90% level of confidence for Cd

Understanding the 8 micron vs. Pa-alpha relationship on sub-arcsecond scales in Luminous Infrared Galaxies

This work explores in detail the relation between the 8 micron and the Pa-alpha emissions for 122 HII regions identified in a sample of 10 low-z LIRGs with nearly constant metallicity (12 + log (O/H) ~ 8.8). We use Gemini/T-ReCS high-spatial resolution (<~ 0.4" ~ 120 pc for the average distance of 60 Mpc of our sample) mid-infrared imaging (at 8.7 micron or 10.3 micron) together with HST/NICMOS continuum and Pa-alpha images. The LIRG HII regions extend the L_8micron vs. L_Pa-alpha relation found for HII knots in the high-metallicity SINGS galaxies by about two orders of magnitude to higher luminosities. Since the metallicity of the LIRG sample is nearly constant, we can rule out this effect as a cause for the scatter seen in the relationship. In turn, it is attributed to two effects: age and PAH features. The L_8micron/L_Pa-alpha ratio, which varies by a factor of ten for the LIRG HII regions, is reproduced by a model with instantaneous star formation and ages ranging from ~ 4 to 7.5 Myr. The remaining dispersion around the model predictions for a given age is probably due to differential contributions of the PAH features (the 8.6 micron, in our case) to the 8 micron emission from galaxy to galaxy.Comment: 16 pages, 9 figures, accepted for publication in ApJ; paper with full-resolution figures can be found at: http://damir.iem.csic.es/extragalactic

Resolved Mid-IR Emission in the Narrow Line Region of NGC 4151

We present subarcsecond resolution mid infrared images of NGC 4151 at 10.8 micron and 18.2 micron. These images were taken with the University of Florida mid-IR camera/spectrometer OSCIR at the Gemini North 8-m telescope. We resolve emission at both 10.8 micron and 18.2 micron extending ~ 3.5" across at a P.A. of ~ 60 degrees. This coincides with the the narrow line region of NGC 4151 as observed in [OIII] by the Hubble Space Telescope. The most likely explanation for this extended mid-IR emission is dust in the narrow line region heated by a central engine. We find no extended emission associated with the proposed torus and place an upper limit on its mid-IR size of less than or equal to ~ 35 pc.Comment: accepted for publication in the Astrophysical Journal, 19 pages including 5 figure

The First Spatially Resolved Mid-IR Spectra of NGC 1068 Obtained at Diffraction-limited Resolution with LWS at Keck I Telescope

We present spatially resolved mid-IR spectra of NGC 1068 with a diffraction-limited resolution of 0.25\arcsec using the Long Wavelength Spectrometer (LWS) at the Keck I telescope. The mid-infrared image of NGC 1068 is extended along the N-S direction. Previous imaging studies have shown the extended regions are located inside the ionization cones indicating that the mid-infrared emission arises perhaps from the inner regions of the narrow-line clouds instead of the proposed dusty torus itself. The spatially resolved mid-IR spectra were obtained at two different slit position angles, +8.0 and -13.0 degrees across the elongated regions in the mid-IR. From these spectra, we found only weak silicate absorption toward the northern extended regions but strong in the nucleus and the southern extended regions. This is consistent with a model of a slightly inclined cold obscuring torus which covers much of the southern regions but is behind the northern extension. While a detailed analysis of the spectra requires a radiative transfer model, the lack of silicate emission from the northern extended regions prompts us to consider a dual dust population model as one of the possible explanations in which a different dust population exists in the ionization cones compared to that in the dusty torus. Dust inside the ionization cones may lack small silicate grains giving rise to only a featureless continuum in the northern extended regions while dust in the dusty torus has plenty of small silicate grains to produce the strong silicate absorption lines towards the nucleus and the southern extended regions.Comment: Accepted to Ap

Recreational Diving Impacts on Coral Reefs and the Adoption of Environmentally Responsible Practices within the SCUBA Diving Industry

Recreational diving on coral reefs is an activity that has experienced rapidly growing levels of popularity and participation. Despite providing economic activity for many developing coastal communities, the potential role of dive impacts in contributing to coral reef damage is a concern at heavily dived locations. Management measures to address this issue increasingly include the introduction of programmes designed to encourage environmentally responsible practices within the dive industry. We examined diver behaviour at several important coral reef dive locations within the Philippines and assessed how diver characteristics and dive operator compliance with an environmentally responsible diving programme, known as the Green Fins approach, affected reef contacts. The role of dive supervision was assessed by recording dive guide interventions underwater, and how this was affected by dive group size. Of the 100 recreational divers followed, 88 % made contact with the reef at least once per dive, with a mean (±SE) contact rate of 0.12 ± 0.01 per min. We found evidence that the ability of dive guides to intervene and correct diver behaviour in the event of a reef contact decreases with larger diver group sizes. Divers from operators with high levels of compliance with the Green Fins programme exhibited significantly lower reef contact rates than those from dive operators with low levels of compliance. The successful implementation of environmentally responsible diving programmes, which focus on influencing dive industry operations, can contribute to the management of human impacts on coral reefs

Viral factors in influenza pandemic risk assessment

The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans. To date, no pandemic emergence of a new influenza strain has been preceded by detection of a closely related precursor in an animal or human. Nonetheless, influenza surveillance efforts are expanding, prompting a need for tools to assess the pandemic risk posed by a detected virus. The goal would be to use genetic sequence and/or biological assays of viral traits to identify those non-human influenza viruses with the greatest risk of evolving into pandemic threats, and/or to understand drivers of such evolution, to prioritize pandemic prevention or response measures. We describe such efforts, identify progress and ongoing challenges, and discuss three specific traits of influenza viruses (hemagglutinin receptor binding specificity, hemagglutinin pH of activation, and polymerase complex efficiency) that contribute to pandemic risk