4,758 research outputs found
Clinical Outcomes of Utilization of Stress Ulcer Prophylaxis in Hospitalized, Non-ICU Patients
Goal
This study is a retrospective chart review that aims to measure the effect of stress ulcer prophylaxis in hospitalized non-ICU level patients to determine the clinical effect of the presence or absence of stress ulcer prophylaxis
Kounis syndrome – Anaphylaxis-induced acute coronary syndrome
Kounis syndrome is an underdiagnosed condition in which anaphylaxis triggers vasospastic acute coronary syndrome, either with or without underlying coronary artery disease. The prevalence of this syndrome among hospitalized patients for allergic/hypersensitivity/anaphylactic reactions in the United States is 1.1%, with a 7% rate of all-cause inpatient mortality. This article presents an anaphylaxis-induced acute coronary syndrome case in a patient with underlying coronary artery disease. The pathophysiological mechanism of anaphylactic-induced acute coronary syndrome involves the inflammatory mediators of type I hypersensitivity reactions
Benefits and Constraints of Vitrification Technologies for Cryopreservation of Bovine In Vitro Fertilized Embryos
Benefits and Constraints of Vitrification Technologies for Cryopreservation of Bovine In Vitro Fertilized Embryos
Comparative study of nonlinear properties of EEG signals of a normal person and an epileptic patient
Background: Investigation of the functioning of the brain in living systems
has been a major effort amongst scientists and medical practitioners. Amongst
the various disorder of the brain, epilepsy has drawn the most attention
because this disorder can affect the quality of life of a person. In this paper
we have reinvestigated the EEGs for normal and epileptic patients using
surrogate analysis, probability distribution function and Hurst exponent.
Results: Using random shuffled surrogate analysis, we have obtained some of
the nonlinear features that was obtained by Andrzejak \textit{et al.} [Phys Rev
E 2001, 64:061907], for the epileptic patients during seizure. Probability
distribution function shows that the activity of an epileptic brain is
nongaussian in nature. Hurst exponent has been shown to be useful to
characterize a normal and an epileptic brain and it shows that the epileptic
brain is long term anticorrelated whereas, the normal brain is more or less
stochastic. Among all the techniques, used here, Hurst exponent is found very
useful for characterization different cases.
Conclusions: In this article, differences in characteristics for normal
subjects with eyes open and closed, epileptic subjects during seizure and
seizure free intervals have been shown mainly using Hurst exponent. The H shows
that the brain activity of a normal man is uncorrelated in nature whereas,
epileptic brain activity shows long range anticorrelation.Comment: Keywords:EEG, epilepsy, Correlation dimension, Surrogate analysis,
Hurst exponent. 9 page
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Information and the gaining of understanding
It is suggested that, in addition to data, information and knowledge, the information sciences should focus on understanding, understood as a higher-order knowledge, with coherent and explanatory potential. The limited ways in which understanding has been addressed in the design of information systems, in studies of information behaviour, in formulations of information literacy, and in impact studies are briefly reviewed, and future prospects considered. The paper is an extended version of a keynote presentation given at the i3 conference in June 2015
NDUFV1 mutations in complex I deficiency: Case reports and review of symptoms.
Mitochondrial complex I (CI) deficiency is the most common oxidative phosphorylation disorder described. It shows a wide range of phenotypes with poor correlation within genotypes. Herein we expand the clinics and genetics of CI deficiency in the brazilian population by reporting three patients with pathogenic (c.640G>A, c.1268C>T, c.1207dupG) and likely pathogenic (c.766C>T) variants in the NDUFV1 gene. We show the mutation c.766C>T associated with a childhood onset phenotype of hypotonia, muscle weakness, psychomotor regression, lethargy, dysphagia, and strabismus. Additionally, this mutation was found to be associated with headaches and exercise intolerance in adulthood. We also review reported pathogenic variants in NDUFV1 highlighting the wide phenotypic heterogeneity in CI deficiency
Interaction Between Convection and Pulsation
This article reviews our current understanding of modelling convection
dynamics in stars. Several semi-analytical time-dependent convection models
have been proposed for pulsating one-dimensional stellar structures with
different formulations for how the convective turbulent velocity field couples
with the global stellar oscillations. In this review we put emphasis on two,
widely used, time-dependent convection formulations for estimating pulsation
properties in one-dimensional stellar models. Applications to pulsating stars
are presented with results for oscillation properties, such as the effects of
convection dynamics on the oscillation frequencies, or the stability of
pulsation modes, in classical pulsators and in stars supporting solar-type
oscillations.Comment: Invited review article for Living Reviews in Solar Physics. 88 pages,
14 figure
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