3,883 research outputs found
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Integration of Direct-Write (DW) and Ultrasonic Consolidation (UC) Technologies to Create Advanced Structures with Embedded Electrical Circuitry
In many instances conductive traces are needed in small, compact and enclosed areas.
However, with traditional manufacturing techniques, embedded electrical traces or antenna
arrays have not been a possibility. By integrating Direct Write and Ultrasonic Consolidation
technologies, electronic circuitry, antennas and other devices can be manufactured directly into a
solid metal structure and subsequently completely enclosed. This can achieve a significant
reduction in mass and volume of a complex electronic system without compromising
performance.Mechanical Engineerin
CONSUMER, WHOLESALER AND RETAILER PERCEPTIONS ABOUT SELECTED MARKETING ISSUES CONCERNING FRESH FISH AND SEAFOOD PRODUCTS
Consumer/Household Economics, Marketing,
Purposeful STEM Integration in School-Based Agricultural Education Programs
The emphasis for STEM integration in school-based agricultural education (SBAE) classrooms is imperative, resulting in a need for teacher educators to generate a positive view on the integration. Specifically, SBAE teacher aspirants need to be prepared to deliver relevant agricultural curriculum grounded in STEM. The purpose of the study was to evaluate the content knowledge and interest in STEM-related careers for secondary students enrolled in SBAE programs in Oklahoma. Pre-service SBAE teachers from Oklahoma State University were charged with delivering a sustainable bioenergy unit of instruction to their students. This study resulted in a statistically significant improvement in students’ STEM knowledge as a result of teaching the content and laboratory experiences (p \u3c .01). Mean scores increased three letter grades and almost 30 percentage points. Unfortunately, minimal differences existed in student interest in STEM as a result of the experience. Future research needs to explore the preparedness of SBAE teachers to develop, teach, and evaluate the impact in all four content areas (i.e., science, technology, engineering, and math). In addition, the results of this study should be used to guide in the evaluation of state standards compared to national SBAE standards
Regulation of B cell fate by chronic activity of the IgE B cell receptor.
IgE can trigger potent allergic responses, yet the mechanisms regulating IgE production are poorly understood. Here we reveal that IgE+ B cells are constrained by chronic activity of the IgE B cell receptor (BCR). In the absence of cognate antigen, the IgE BCR promoted terminal differentiation of B cells into plasma cells (PCs) under cell culture conditions mimicking T cell help. This antigen-independent PC differentiation involved multiple IgE domains and Syk, CD19, BLNK, Btk, and IRF4. Disruption of BCR signaling in mice led to consistently exaggerated IgE+ germinal center (GC) B cell but variably increased PC responses. We were unable to confirm reports that the IgE BCR directly promoted intrinsic apoptosis. Instead, IgE+ GC B cells exhibited poor antigen presentation and prolonged cell cycles, suggesting reduced competition for T cell help. We propose that chronic BCR activity and access to T cell help play critical roles in regulating IgE responses
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OASIS: an automated program for global investigation of bacterial and archaeal insertion sequences
Insertion sequences (ISs) are simple transposable elements present in most bacterial and archaeal genomes and play an important role in genomic evolution. The recent expansion of sequenced genomes offers the opportunity to study ISs comprehensively, but this requires efficient and accurate tools for IS annotation. We have developed an open-source program called OASIS, or Optimized Annotation System for Insertion Sequences, which automatically annotates ISs within sequenced genomes. OASIS annotations of 1737 bacterial and archaeal genomes offered an unprecedented opportunity to examine IS evolution. At a broad scale, we found that most IS families are quite widespread; however, they are not present randomly across taxa. This may indicate differential loss, barriers to exchange and/or insufficient time to equilibrate across clades. The number of ISs increases with genome length, but there is both tremendous variation and no increase in IS density for genomes >2 Mb. At the finer scale of recently diverged genomes, the proportion of shared IS content falls sharply, suggesting loss and/or emergence of barriers to successful cross-infection occurs rapidly. Surprisingly, even after controlling for 16S rRNA sequence divergence, the same ISs were more likely to be shared between genomes labeled as the same species rather than as different species.Organismic and Evolutionary Biolog
Socio-economic impact of Rift Valley fever to pastoralists and agro pastoralists in Arusha, Manyara and Morogoro regions in Tanzania
Rift Valley fever (RVF) is a viral notifiable zoonotic disease primarily of domestic ruminants that causes significant socio-economic impacts. Using the 2006–07 outbreak cases, this study aimed to establish the socio-economic impact of RVF and assessing knowledge, attitude and practice of livestock keepers towards controlling RVF in selected areas of Tanzania. Data were collected in Arusha, Manyara and Morogoro regions using questionnaires, focus group discussions and in-depth interviews with key informants. Results indicate that there was little knowledge on disease (all clinical signs scored <50%) and the difference between the three regions was statistically significant (P = 0.00459). Socio-economic impacts of RVF shown by this study included; animal and human deaths, disruption of livestock market chains, inability of pastoralists to achieve their daily demands, inability to obtain protein leading to malnutrition and monetary loss at individual and national level during control of the disease. These findings have demonstrated low knowledge of the community on RVF, thus, more education and engagement is needed in order to develop more effective and efficient control strategies
Large-Scale Outflows in Edge-on Seyfert Galaxies. III. Kiloparsec-Scale Soft X-ray Emission
We present ROSAT PSPC and HRI images of eight galaxies selected from a
distance-limited sample of 22 edge-on Seyfert galaxies. Kiloparsec-scale soft
X-ray nebulae extend along the galaxy minor axes in three galaxies (NGC 2992,
NGC 4388 and NGC 5506). The extended X-ray emission has 0.2-2.4 keV X-ray
luminosities of . The X-ray nebulae are
roughly co-spatial with the large-scale radio emission, suggesting that both
are produced by large-scale galactic outflows. Assuming pressure balance
between the radio and X-ray plasmas, the X-ray filling factor is \gapprox
10^4 times larger than the radio plasma filling factor, suggesting that
large-scale outflows in Seyfert galaxies are predominantly winds of thermal
X-ray emitting gas. We favor an interpretation in which large-scale outflows
originate as AGN-driven jets that entrain and heat gas on kpc scales as they
make their way out of the galaxy. AGN- and starburst-driven winds are also
possible explanations in cases where the winds are oriented along the rotation
axis of the galaxy disk.Comment: 24 pages, 7 ps figures, AASTEX 4.0, accepted for ApJ April 1, 199
Ignition Characterization Test Results for the LO2/Ethanol Propellant Combination
A series of contracts were issued by the Marshall Space Flight Center (MSFC) of the National Aeronautics and Space Administration (NASA) under the auspices of the Exploration Systems Mission Directorate to develop and expand the maturity of candidate technologies considered to be important for future space exploration. One such technology was to determine the viability of incorporating non-toxic propellants for Reaction Control Subsystems (RCS). Contract NAS8-01109 was issued to Aerojet to develop a dual thrust Reaction Control Engine (RCE) that utilized liquid oxygen and ethanol as the propellants. The dual thrust RCE incorporated a primary thrust level of 870 lbf, and a vernier thrust level of 10 - 30 lbf. The preferred RCS approach for the dual thrust RCE was to utilize pressure-fed liquid oxygen (LOX) and ethanol propellants; however, previous dual thrust feasibility testing incorporated GOX/Ethanol igniters as opposed to LOX/Ethanol igniters in the design. GOX/Ethanol was easier to ignite, but this combination had system design implications of providing GOX for the igniters. A LOX/Ethanol igniter was desired; however, extensive LOX/Ethanol ignition data over the anticipated operating range for the dual thrust RCE did not exist. Therefore, Aerojet designed and tested a workhorse LOX igniter to determine LOX/Ethanol ignition characteristics as part of a risk mitigation effort for the dual thrust RCE design. LOX, encompassing potential two-phase flow conditions anticipated being present in real mission applications. A workhorse igniter was designed to accommodate the hll LOX design flowrate, as well as a reduced GOX flowrate. It was reasoned that the initial LOX flow through the igniter would flash to GOX due to the latent heat stored in the hardware, causing a reduced oxygen flowrate because of a choked, or sonic, flow condition through the injection elements. As LOX flow continued, the hardware would chill-in, with the injected oxygen flow transitioning from cold GOX through two-phase flow to subcooled LOX. permitted oxygen state points to be determined in the igniter oxidizer manifold, and gas-side igniter chamber thermocouples provided chamber thermal profile characteristics. The cold flow chamber pressure (P(sub c)) for each test was determined and coupled with the igniter chamber diameter (D(sub c)) to calculate the characteristic quench parameter (P(sub c) x D(sub c)), which was plotted as a function of core mixture ratio, m. Ignition limits were determined over a broad range of valve inlet conditions, and ignition was demonstrated with oxygen inlet conditions that ranged from subcooled 210 R LOX to 486 R GOX. Once ignited at cold GOX conditions, combustion was continuous as the hardware chilled in and the core mixture ratio transitioned from values near 1.0 to over 12.5. Pulsing is required in typical RCS engines; therefore, the workhorse igniter was pulse tested to verify the ability to provide the required ignition for a pulsing RCE. The minimum electrical pulse width (EPW) of the dual thrust RCE was 0.080 seconds
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