The effect of a suggestive interview on children’s memory of a repeated event: Does it matter whether suggestions are linked to a particular incident?

This study examined the impact of linking misleading information to a particular occurrence of a repeated event. Children aged 5- to 6-years took part in the same staged event four times and 16 target details varied in each occurrence (e.g., the colour of a cloak varied each time). Three days or three weeks later they were asked questions, some of which included false information, about the final occurrence. The next day, the children were required to recall what happened in the final occurrence. Compared to children whose biasing interview was not focused on any particular occurrence of the repeated event, linking the biasing interview to the final occurrence increased the number of suggested details that were reported. Interestingly, the children whose biasing interview was not focused on any occurrence were also less likely to report the false suggestions than another group of children who had only experienced the event once and whose biasing interview was linked to that single occurrence. These findings have implications for how lawyers and investigative interviewers question children about multiple incidents

The impact of experienced versus non-experienced suggestions on children’s recall of repeated events

Three experiments were conducted to test the proposition that children’s suggestibility about an occurrence of a repeated event is heightened when an interviewer suggests false details that were experienced in non-target occurrences of the event as opposed to new details that never occurred. In each experiment, children participated in a repeated event during which specific items varied each time (e.g., the children always got a sticker but the theme of the sticker was different in each occurrence). Separate biasing and memory interviews were then conducted. In Experiment 1, the interviewer merely suggested that the false details might have occurred in the event. In the remaining experiments, the suggested details were clearly linked to the target occurrence with either a contextual or temporal cue. The potential moderating effect of the child’s age (Experiment 1) and the retention interval (Experiments 1 and 2) were also examined. Consistent with the initial hypothesis, suggestions about experienced (non-target) details were more likely to be repeated by the children compared to suggestions about non-experienced details. In Experiments 2 and 3, experienced suggestions were also more likely to inhibit children’s recall of the target occurrence. The relevance and generalisability of these findings to the legal setting are discussed

Anomalous translational velocity of vortex ring with finite-amplitude Kelvin waves

We consider finite-amplitude Kelvin waves on an inviscid vortex assuming that the vortex core has infinitesimal thickness. By numerically solving the governing Biot-Savart equation of motion, we study how the frequency of the Kelvin waves and the velocity of the perturbed ring depend on the Kelvin wave amplitude. In particular, we show that, if the amplitude of the Kelvin waves is sufficiently large, the perturbed vortex ring moves backwards.Comment: 6 pages, 5 figures, v2: minor changes, v3: typos correcte

Clinical impact of early post-transplant red cell transfusions in kidney transplantation: a systematic review and meta-analysis

Introduction: Red blood cell transfusions (RBCT) represent a potentially modifiable risk factor for HLA sensitisation and adverse outcomes post transplantation. Evidence of the clinical impact of post-transplant RBCT has been infrequently reported. Herein, we performed a systematic review of available literature to assess the prevalence of RBCT post kidney transplant, and the effect of transfusion on transplant outcomes. Methods: We included studies from 2000 to July 2022, published on Medline, Embase and the Transplant Library. Results: Ten studies were analysed which included a total of 32,817 kidney transplant recipients, with a median transfusion prevalence of 40% (range 18-64%). There was significant heterogeneity between studies in terms of patient and allograft characteristics, immunological risk, and immunosuppression protocols. Analysis of unadjusted outcomes showed that post-transplant RBCTs are associated with inferior patient survival, allograft loss, rejection and donor specific antibodies. Adjusted outcomes were described where available, and supported the adverse associations seen in the unadjusted models in many studies. Discussion: This review demonstrates that RBCT post-transplant are common and maybe associated with inferior outcomes, highlighting the urgent need for high quality prospective evidence of the effect of RBCTs on transplant outcomes. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier, CRD42022348763767

Ground-state Spectrum of Light-quark Mesons

A confining, Goldstone theorem preserving, separable Ansatz for the ladder kernel of the two-body Bethe-Salpeter equation is constructed from phenomenologically efficacious $u$, $d$ and $s$ dressed-quark propagators. The simplicity of the approach is its merit. It provides a good description of the ground-state isovector-pseudoscalar, vector and axial-vector meson spectrum; facilitates an exploration of the relative importance of various components of the two-body Bethe-Salpeter amplitudes, showing that sub-leading Dirac components are quantitatively important in the isovector-pseudoscalar meson channels; and allows a scrutiny of the domain of applicability of ladder truncation studies. A colour-antitriplet diquark spectrum is obtained. Shortcomings of separable Ans\"atze and the ladder kernel are highlighted.Comment: 30 pages, LaTeX/REVTEX 3.0, no figure

Complete Genome Sequence and Comparative Metabolic Profiling of the Prototypical Enteroaggregative Escherichia coli Strain 042

Background \ud Escherichia coli can experience a multifaceted life, in some cases acting as a commensal while in other cases causing intestinal and/or extraintestinal disease. Several studies suggest enteroaggregative E. coli are the predominant cause of E. coli-mediated diarrhea in the developed world and are second only to Campylobacter sp. as a cause of bacterial-mediated diarrhea. Furthermore, enteroaggregative E. coli are a predominant cause of persistent diarrhea in the developing world where infection has been associated with malnourishment and growth retardation. \ud \ud Methods \ud In this study we determined the complete genomic sequence of E. coli 042, the prototypical member of the enteroaggregative E. coli, which has been shown to cause disease in volunteer studies. We performed genomic and phylogenetic comparisons with other E. coli strains revealing previously uncharacterised virulence factors including a variety of secreted proteins and a capsular polysaccharide biosynthetic locus. In addition, by using Biolog™ Phenotype Microarrays we have provided a full metabolic profiling of E. coli 042 and the non-pathogenic lab strain E. coli K-12. We have highlighted the genetic basis for many of the metabolic differences between E. coli 042 and E. coli K-12. \ud \ud Conclusion \ud This study provides a genetic context for the vast amount of experimental and epidemiological data published thus far and provides a template for future diagnostic and intervention strategies

Effects of a museum-based social-prescription intervention on quantitative measures of psychological wellbeing in older adults

Aims: To assess psychological wellbeing in a novel social prescription intervention for older adults called Museums on Prescription, and to explore the extent of change over time in six self-rated emotions (‘absorbed, ‘active’, ‘cheerful’, ‘encouraged’, ‘enlightened’ and ‘inspired’). Methods: Participants (n=115) aged 65-94 were referred to museum-based programmes comprising 10, weekly sessions, by healthcare and third sector organisations using inclusion criteria (e.g. socially isolated; able to give informed consent; not in employment; not regularly attending social or cultural activities) and exclusion criteria (e.g. unable to travel to the museum; unable to function in a group situation; unlikely to be able to attend all sessions; unable to take part in interviews and complete questionnaires). In a within-participants design, the Museum Wellbeing Measure for Older Adults (MWM-OA) was administered pre-post session at start- mid- and end-programme. Twelve programmes, facilitated by museum staff and volunteers, were conducted in seven museums in central London and across Kent. In addition to the quantitative measures, participants, carers where present, museum staff and researchers kept weekly diaries following guideline questions, and took part in end programme in-depth interviews. Results: Multivariate analyses of variance showed significant participant improvements in all six MWM-OA emotions, pre-post session at start- mid- and end-programme. Two emotions, ‘absorbed’ and ‘enlightened’, increased pre-post session disproportionately to the others; ‘cheerful’ attained the highest pre-post session scores whereas ‘active’ was consistently lowest. Conclusions: Museums can be instrumental in offering museum-based programmes for older adults to improve psychological wellbeing over time. Participants in the study experienced a sense of privilege, valued the opportunity to liaise with curators, visit parts of the museum closed to the public, and handle objects normally behind glass. Participants appreciated opportunities afforded by creative and co-productive activities to acquire learning and skills, and get to know new people in a different context

The shell elliptical NGC2865: evolutionary population synthesis of a kinematically distinct core

We report on the discovery of a rapidly co-rotating stellar and gas component in the nucleus of the shell elliptical NGC2865. The stellar component extends ~ 0.51/h100 kpc along the major axis, and shows depressed velocity dispersion and absorption line profiles skewed in the opposite sense to the mean velocity. Associated with it is a young stellar population with enhanced \hbeta, lowered Mg and same Fe indices relative to the underlying elliptical. Its recent star formation history is constrained by considering ``bulge+burst'' models under 4 physically motivated scenarios, using evolutionary population synthesis. Scenarios in which the nuclear component is formed over a Hubble time or recently from continuous gas inflow are ruled out. Our results argue for a gas-rich accretion or merger origin for the shells and kinematic subcomponent in NGC2865. Arguments based on stellar populations and gas dynamics suggest that one of the progenitors is likely a Sb or Sc spiral. We demonstrate that despite the age and metallicity degeneracy of the underlying elliptical, the age and metallicity of the kinematic subcomponent can be constrained. This work strengthens the link between KDCs and shells, and demonstrates that a KDC can be formed from a late merger.Comment: 26 pages, accepted for publication in MNRA

Ten principles relevant to health research among Indigenous Australian populations

Writing in the Journal about Indigenous health in 2011, Sir Michael Marmot suggested that the challenge was to conduct research, and to ultimately apply findings from that research, to enable Indigenous Australians to lead more flourishing lives that they would have reason to value.1 As committed Indigenous health researchers in Australia, we reflect Marmot’s ideal — to provide the answers to key questions relating to health that might enable Indigenous Australians to live the lives that they would choose to live.As a group, we have over 120 collective years’ experience in Indigenous health research. Over this time, particularly in recent years as ethical guidelines have come into play, there have been many examples of research done well. However, as the pool of researchers is constantly replenished, we hold persisting concerns that some emerging researchers may not be well versed in the principles of best practice regarding research among Indigenous Australian populations. Implementing any research methodology among Indigenous Australian groups will work best when the following 10 principles are met. These principles are reflected in the many documents related to working and researching with Indigenous Australians; for example, the National Health and Medical Research Council (NHMRC) ethical guidelines for research among Aboriginal and Torres Strait Islander people.2 In this article, we set out these principles in one short, accessible document