Two-particle bosonic-fermionic quantum walk via 3D integrated photonics

Quantum walk represents one of the most promising resources for the simulation of physical quantum systems, and has also emerged as an alternative to the standard circuit model for quantum computing. Up to now the experimental implementations have been restricted to single particle quantum walk, while very recently the quantum walks of two identical photons have been reported. Here, for the first time, we investigate how the particle statistics, either bosonic or fermionic, influences a two-particle discrete quantum walk. Such experiment has been realized by adopting two-photon entangled states and integrated photonic circuits. The polarization entanglement was exploited to simulate the bunching-antibunching feature of non interacting bosons and fermions. To this scope a novel three-dimensional geometry for the waveguide circuit is introduced, which allows accurate polarization independent behaviour, maintaining a remarkable control on both phase and balancement.Comment: 4 pages, 5 figures + supplementary informatio

LaserCube optical communication terminal for nano and micro satellites

This paper presents the design and testing of LaserCube, a miniature optical communication terminal conceived for nano and microsatellites. The system architecture has been designed for both the downlink and intersatellite link version of the system. Then, a complete engineering model of LaserCube in its intersatellite link configuration has been developed and tested. It features (1) a dual stage pointing and tracking system based on a coarse pointing mechanism patented by Stellar Project, (2) an optical head with a full-duplex telecom channel with transmission and reception on the same wavelength for two-way links, (3) a transceiver section with telecom laser source and optical receiver and (4) the terminal control unit with onboard computer, actuator drivers and data interface. Experimental validation of the system is achieved through a laboratory simulation of an intersatellite link scenario with realistic dynamic disturbance coming from the host satellite attitude jitter

Database of Individual Seismogenic Sources (DISS), Version 3.2.1: A compilation of potential sources for earthquakes larger than M 5.5 in Italy and surrounding areas

Istituto Nazionale di Geofisica e VulcanologiaPublished2T. Deformazione crostale attiva3T. Sorgente sismica4T. Sismicità dell'Italia5T. Sismologia, geofisica e geologia per l'ingegneria sismica6T. Studi di pericolosità sismica e da maremoto4IT. Banche dat

MICROTREMOR MEASUREMENTS IN PALERMO, ITALY: A COMPARISON WITH MACROSEISMIC INTENSITY AND EARTHQUAKE GROUND MOTION

The city of Palermo is an appropriate test site where the efficiency of microtremors in predicting ground motion properties during earthquakes can be checked. Palermo is a densely populated city with important historical heritage and was object of previous studies. Areas of local amplification of damage were identified in downtown Palermo using historical macroseismic data. Moreover, aftershocks of the September 6, 2002, earthquake (Mw 5.9, 40 km offshore) provided a dataset of seismograms that quantify spatial variations of ground motion. The availability of more than 2000 boreholes in the city allowed a reconstruction of the 3D structure of surface geology, indicating that all the higher damage zones correspond to sediment-filled valleys. The high variability of the surface geology is mostly due to the presence of two filled river-beds of about 150 m width. In the framework of the SESAME project (Seismic EffectS assessment using Ambient Exctations, funded by the European Union), 90 microtremor measurements were performed across several profiles crossing the soft sediment bodies. The measurement points were intensified close to the valley edges (every 20 m), according to our geological reconstruction. H/V spectral ratio on ambient noise (HVSR) show significant variations along each profile: as soon as the transition stiff to soft is crossed, a typical spectral peak exceeding a factor of 3 in amplitude appears in the HVSR. The peak falls between 1 and 2 Hz and, along each profile, the peak disappears as soon as the other edge of the valley is crossed. These results indicate that microtremors are sensitive to the presence of large impedance contrasts of deep soft soil, at least in the Palermo area, with an important implication: the HVSR method seems to be able to recognize conditions potentially favourable to the occurrence of higher damage even when local geological characters are masked by the urban growth. However, we were not able to establish a quantitative correlation between microtremor properties and ground motion (or damage) amplification

Aberrant RET expression impacts on normal mammary gland post-lactation transition enhancing cancer potential

RET is a receptor tyrosine kinase with oncogenic potential in the mammary epithelium. Several receptors with oncogenic activity in the breast are known to participate in specific developmental stages. We found that RET is differentially expressed during mouse mammary gland development: RET is present in lactation and its expression dramatically decreases in involution, the period during which the lactating gland returns to a quiescent state after weaning. Based on epidemiological and pre-clinical findings, involution has been described as tumor promoting. Using the Ret/MTB doxycycline-inducible mouse transgenic system we show that sustained expression of RET in the mammary epithelium during the post-lactation transition to involution is accompanied by alterations in tissue remodeling and an enhancement of cancer potential. Following constitutive Ret expression we observed a significant increase in neoplastic lesions in the post-involuting versus the virgin mammary gland. Furthermore, we show that abnormal RET overexpression during lactation promotes factors that prime involution, including premature activation of Stat3 signaling and, using RNA-seq, an acute-phase inflammatory signature. Our results demonstrate that RET overexpression negatively affects the normal post-lactation transition.Fil: Vallone, Sabrina Aldana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Garcia Sola, Martin Emilio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Schere Levy, Carolina Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Meiss, Roberto P.. Academia Nacional de Medicina de Buenos Aires; ArgentinaFil: Hermida, Gladys Noemí. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Chodosh, Lewis A.. University of Pennsylvania; Estados UnidosFil: Kordon, Edith Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Hynes, Nancy E.. Friedrich Miescher Institute For Biomedical Research; SuizaFil: Gattelli, Albana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentin

Severe Heterotopic Ossification in the Skeletal Muscle and Endothelial Cells Recruitment to Chondrogenesis Are Enhanced by Monocyte/Macrophage Depletion

Altered macrophage infiltration upon tissue damage results in inadequate healing due to inappropriate remodeling and stem cell recruitment and differentiation. We investigated in vivo whether cells of endothelial origin phenotypically change upon heterotopic ossification induction and whether infiltration of innate immunity cells influences their commitment and alters the ectopic bone formation. Liposome-encapsulated clodronate was used to assess macrophage impact on endothelial cells in the skeletal muscle upon acute damage in the ECs specific lineage-tracing Cdh5CreER(T2):R26REYFP/dtTomato transgenic mice. Macrophage depletion in the injured skeletal muscle partially shifts the fate of ECs toward endochondral differentiation. Upon ectopic stimulation of BMP signaling, monocyte depletion leads to an enhanced contribution of ECs chondrogenesis and to ectopic bone formation, with increased bone volume and density, that is reversed by ACVR1/SMAD pathway inhibitor dipyridamole. This suggests that macrophages contribute to preserve endothelial fate and to limit the bone lesion in a BMP/injury-induced mouse model of heterotopic ossification. Therefore, alterations of the macrophage-endothelial axis may represent a novel target for molecular intervention in heterotopic ossification

A Blind Circadian Clock in Cavefish Reveals that Opsins Mediate Peripheral Clock Photoreception

Evolution during millions of years in perpetual darkness leads to mutations in non-visual opsin genes (Melanopsin and TMT opsin) and an aberrant, blind circadian clock in cavefish

Surface ruptures database related to the 26 December 2018, MW 4.9 Mt. Etna earthquake, southern Italy

We provide a database of the surface ruptures produced by the 26 December 2018 Mw 4.9 earthquake that struck the eastern flank of Mt. Etna volcano in Sicily (southern Italy). Despite its relatively small magnitude, this shallow earthquake caused about 8 km of surface faulting, along the trace of the NNW-trending active Fiandaca Fault. Detailed field surveys have been performed in the epicentral area to map the ruptures and to characterize their kinematics. The surface ruptures show a dominant right-oblique sense of displacement with an average slip of about 0.09 m and a maximum value of 0.35 m. We have parsed and organized all observations in a concise database, with 932 homogeneous georeferenced records. The Fiandaca Fault is part of the complex active Timpe faults system affecting the eastern flank of Etna, and its seismic history indicates a prominent surface-faulting potential. Therefore, this database is essential for unravelling the seismotectonics of shallow earthquakes in volcanic areas, and contributes updating empirical scaling regressions that relate magnitude and extent of surface faulting.Publishedid 422T. Deformazione crostale attivaJCR Journa